Abstract: Provided are a piperidine derivative compound, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for the prevention or treatment of diseases related to autotaxin activity, comprising same as an active ingredient, in which the piperidine derivative compound exhibits excellent inhibitory activity against autotaxin, and thus can be effectively used in the treatment and prevention of diseases related to autotaxin inhibition, such as fibrotic diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, metabolic diseases, cancer and cancer metastasis, ocular diseases, cholestatic form and other forms of chronic pruritus, and acute or chronic organ transplant rejection.

Abstract: An inhaler includes a housing having one surface, the other surface opposite to the one surface, and a plurality of side surfaces connecting the one surface and the other surface, a mouthpiece which is disposed on the one side of the housing, a reservoir which is disposed inside the housing and stores an inhalable composition, a nozzle which extends from the mouthpiece to the reservoir, and a needle valve which is movably disposed inside the nozzle, when a suction force is not applied to the mouthpiece, the needle valve is maintained in a first state in which the nozzle is closed, and when a suction force is applied through the mouthpiece, the needle valve is switched into a second state in which the nozzle is opened.

Abstract: Disclosed herein are acylated active agents and methods of their use, e.g., for modulating an autoimmunity marker or for treating an autoimmune disorder.

Abstract: Provided are a piperidine derivative compound, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for the prevention or treatment of diseases related to autotaxin activity, comprising same as an active ingredient, in which the piperidine derivative compound exhibits excellent inhibitory activity against autotaxin, and thus can be effectively used in the treatment and prevention of diseases related to autotaxin inhibition, such as fibrotic diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, metabolic diseases, cancer and cancer metastasis, ocular diseases, cholestatic form and other forms of chronic pruritus, and acute or chronic organ transplant rejection.

Abstract: Provided is an organic electroluminescence device including a first electrode, an organic layer on the first electrode, and a second electrode on the organic layer, wherein the organic layer includes a polycyclic compound represented by Formula 1. The organic electroluminescence device including a polycyclic compound represented by Formula 1 thereby exhibits high luminous efficiency.

Abstract: An aerosol-generating device includes a receiver for receiving a medium receiving rod in a replaceable manner, an atomizer that generates aerosol, and a power supply for providing power required to heat the atomizer, and a medium included in the medium receiving rod is transferred by the aerosol passing through the medium receiving rod.

Abstract: A display device includes a first pixel including a first emission area formed to emit light having a first color in a third direction, a second pixel including a second emission area formed to emit light having a second color different from the first color, a first partition wall in which a first opening overlapping the first emission area in a plan view is defined, a second partition wall in which a second opening overlapping the second emission area in the plan view is defined, and a first layer covering the first partition wall and the second partition wall. The first partition may be provided with a first height in the third direction. The second partition wall may be provided with a second height different from the first height.

Abstract: A display device including: a substrate; a plurality of light-emitting elements on the substrate; and a touch sensing layer disposed on the plurality of light-emitting elements, wherein the touch sensing layer includes: a first touch conductive layer; a first insulating layer disposed on the first touch conductive layer; and a second touch conductive layer disposed on the first insulating layer, and wherein the first insulating layer includes a light-converting material that converts light into near-infrared light.

Abstract: The aerosol-generating device includes a receiver for receiving a medium receiving rod in a replaceable manner, an atomizer that generates aerosol, and a power supply for transmitting power required to heat the atomizer, wherein the aerosol generated in the atomizer passes through the medium receiving rod received in the receiver such that a medium is transferred from medium pulp included in a filter segment of the medium receiving rod by heat of the aerosol.

Abstract: In an embodiment, an ionomer includes a partial structure represented by: wherein z is an integer of 1 to 10.

Abstract: Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.

Abstract: An optical filter includes a near-infrared absorbing layer including a first material, the first material being configured to absorb light in a first wavelength spectrum belonging to a near-infrared wavelength spectrum. The optical filter includes a compensation layer adjacent to the near-infrared absorbing layer, the compensation layer including a second material different from the first material. The optical filter includes a metamaterial structure spaced apart from the near-infrared absorbing layer via the compensation layer, the metamaterial structure being configured to absorb or reflect light in a second wavelength spectrum at least partially overlapped with the first wavelength spectrum.

Abstract: Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.

Abstract: A compound is represented by Formula 1 below: wherein R1 to R4 are each independently a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a fluoro-substituted alkyl group having 1 to 6 carbon atoms, or a fluorine atom, wherein at least one among R1 to R4 is a fluorine atom, A is a divalent linking group, M1 and M2 are each independently potassium or sodium, and n and m are each independently an integer of 1 to 10.

Abstract: The present invention relates to mouse antibodies that bind to angiopoietin-2 (Ang2), humanized anti-Ang2 antibodies derived therefrom, and the use thereof. The anti-Ang2 antibodies have a dual function of activating the Tie2 receptor together with neutralizing Ang2. The anti-Ang2 antibodies show the property of normalizing abnormal and pathological blood vessels, and thus exhibits therapeutic efficacy against various diseases and disorders associated with abnormal blood vessels. The present invention further provides an angiogenesis inhibitor and a composition for treatment of diseases associated with abnormal Ang2 expression and Tie2 dysregulation, which comprise the antibody as an active ingredient, and a composition for diagnosing diseases associated with Ang2 inhibition and Tie2 activation, which comprises the antibody.

Abstract: Disclosed are a combination structure including a nanostructure array including a plurality of nanostructures with a smaller dimension than the near-infrared wavelength are repeatedly arranged and a light absorption portion adjacent to the nanostructure array and including a near-infrared absorbing material configured to absorb light in at least a portion of near-infrared wavelength regions, an optical filter, an image sensor, a camera module, and an electronic device including the same.

Abstract: A combination structure includes an in-plane pattern of unit cells, wherein the each unit cell includes nanostructures each having a dimension that is smaller than a near-infrared wavelength and a light-absorbing layer adjacent to the nanostructures and including a near-infrared absorbing material configured to absorb light in at least a portion of a near-infrared wavelength spectrum. The nanostructures are define a nanostructure array in the unit cells, and a wavelength width at 50% transmittance of a transmission spectrum in the near-infrared wavelength spectrum of the combination structure is wider than a wavelength width at 50% transmittance of a transmission spectrum in the near-infrared wavelength spectrum of the nanostructure array.

Abstract: Disclosed are an optical structure, and a camera module and an electronic device including the same. The optical structure includes a transparent substrate; a first moisture-proof layer disposed on the transparent substrate and including a first organic material having moisture-proof properties; and a first near-infrared absorbing layer disposed between the transparent substrate and the first moisture-proof layer and including a copper complex, wherein the first organic material having moisture-proof properties has a water vapor transmission rate (WVTR) of less than or equal to about 100 g/m2/day measured at a thickness of 100 ?m.

Abstract: An optical filter includes a light absorbing layer and a conductive nanodisk. The light absorbing layer includes a near-infrared absorbing material configured to absorb light of a first wavelength spectrum within a near-infrared wavelength spectrum. The conductive nanodisk is configured to absorb or reflect light of a second wavelength spectrum within the first wavelength spectrum. An image sensor includes the optical filter, a camera module includes the optical filter, and an electronic device includes the optical filter.

Abstract: A combination structure includes an in-plane pattern of unit cells, wherein the each unit cell includes nanostructures each having a dimension that is smaller than a near-infrared wavelength and a light-absorbing layer adjacent to the nanostructures and including a near-infrared absorbing material configured to absorb light in at least a portion of a near-infrared wavelength spectrum. The nanostructures are define a nanostructure array in the unit cells, and a wavelength width at 50% transmittance of a transmission spectrum in the near-infrared wavelength spectrum of the combination structure is wider than a wavelength width at 50% transmittance of a transmission spectrum in the near-infrared wavelength spectrum of the nanostructure array.