Abstract: The present disclosure relates to a cell-penetrating peptide, an anticancer peptide, and a pharmaceutical composition for preventing or treating cancer including the same. The cell-penetrating peptide of the present disclosure can further improve a cancer cell growth inhibitory effect of anticancer peptides, especially cancer therapeutic peptides with improved anticancer activity by cyclic structures, and thus can be effectively applied to the prevention or treatment of various cancers.

Abstract: Disclosed is a blankmask for EUV lithography. The blankmask has a reflective film formed on a substrate, a capping film containing ruthenium (Ru), an etch stop film containing tantalum (Ta) and antimony (Sb), and a phase shift film containing ruthenium (Ru). The etch stop film has a composition ratio of tantalum (Ta) and antimony (Sb) ranging from 3:7 to 7:3. The stacked structure of the phase shift film containing ruthenium (Ru) and the etch stop film containing tantalum (Ta) and antimony (Sb) results in achieving a high extinction coefficient (k) and a low refractive index (n).

Abstract: In one aspect of the present invention, there is provided a pharmaceutical formulation having a pH of 4.0 to 8.0, comprising (a) an HL161BKN antibody or a fragment thereof, (b) at least one additive selected from mannitol, sorbitol, arginine, histidine, glycine and salts thereof, (c) a buffer system selected from citrate or histidine, and (d) a surfactant. HL161BKN present in the formulation has improved stability and is non-toxic, and thus has a high potential for industrial application.

Abstract: A fusion protein contains an FGF21 mutant protein and an Fc region of an immunoglobulin. The fusion protein exhibits improved pharmacological efficacy, in vivo duration and protein stability. A pharmaceutical composition containing the fusion protein as an active ingredient may be effectively used as a therapeutic agent for diabetes, obesity, dyslipidemia, metabolic syndrome, non-alcoholic fatty liver disease or non-alcoholic steatohepatitis.

Abstract: The present disclosure relates to a biomarker for diagnosis of oral cancer, using metabolite profiling and, more specifically, to a biomarker composition containing an acyl carnitine metabolite which varies in quantity upon the onset of oral cancer, and a diagnostic method for oral cancer, using same. The present disclosure allows for the early diagnosis of oral cancer which has been conventionally difficult to diagnose due to the impossible tissue biopsy thereof, and can reduce the pain and risk burden of patients because it uses a liquid biopsy method in which a blood sample is collected and analyzed.

Abstract: Discussed is a light emitting device including a first electrode and a second electrode facing each other, a hole transport layer, a first emission layer, and an electron transport layer sequentially disposed between the first electrode and the second electrode. In the transport layer, a first material of a metal halide and a second material of an n-type inorganic compound are included. The second material is included as a dopant in the first material. The hole transport layer can contain no organic material and can be amorphous.

Abstract: An infrared adaptive transparent camouflage film includes a substrate, a graphene layer, an electrode layer and an ion gel layer. The substrate has dielectric. The graphene layer is disposed on the substrate and stacked in multiple layer. The electrode layer is disposed over the substrate and is spaced apart from the graphene layer. The ion gel layer is disposed over the graphene layer and the electrode layer, or disposed between the graphene layer and the electrode layer, to dope the graphene layer electrically.

Abstract: The present invention relates to an epitope of a thioredoxin-1 (Trx1) antigen and a use thereof, and more particularly, to the epitope, and an antibody or an antigen-binding fragment binding thereto. The epitope region of the human Trx1 antigen confirmed in the present invention may be effectively used in the development of an improved antibody to enhance the binding affinity of an anti-Trx1 antibody. In addition, the improved antibody of the present invention is effective in improvement of performance of a breast cancer diagnosis kit due to excellent binding affinity for Trx1 and very high sensitivity and specificity, compared to a conventional anti-Trx1 antibody. Further, the accuracy and reliability of breast cancer diagnosis may significantly increase because exceptionally high sensitivity and specificity are exhibited by detecting the monoclonal antibody of the present invention, which specifically binds to Trx1, rather than detecting CA15-3, another conventional breast cancer diagnostic biomarker.

Abstract: Provided are a fluorinated compound for patterning a metal or an electrode (cathode), an organic electronic element using the same, and an electronic device thereof, wherein by using the fluorinated compound as a material for patterning a metal or an electrode (cathode), it is possible to form a fine pattern of the electrode without using a shadow mask, since it is easy to manufacture a transparent display having high light transmittance, it is possible to more easily apply UDC.

Abstract: The present invention relates to an epitope of a thioredoxin-1 (Trx1) antigen and a use thereof, and more particularly, to the epitope, and an antibody or an antigen-binding fragment binding thereto. The epitope region of the human Trx1 antigen confirmed in the present invention may be effectively used in the development of an improved antibody to enhance the binding affinity of an anti-Trx1 antibody. In addition, the improved antibody of the present invention is effective in improvement of performance of a breast cancer diagnosis kit due to excellent binding affinity for Trx1 and very high sensitivity and specificity, compared to a conventional anti-Trx1 antibody. Further, the accuracy and reliability of breast cancer diagnosis may significantly increase because exceptionally high sensitivity and specificity are exhibited by detecting the monoclonal antibody of the present invention, which specifically binds to Trx1, rather than detecting CA15-3, another conventional breast cancer diagnostic biomarker.

Abstract: The present invention relates to an epitope of a thioredoxin-1 (Trx1) antigen and a use thereof, and more particularly, to the epitope, and an antibody or an antigen-binding fragment binding thereto. The epitope region of the human Trx1 antigen confirmed in the present invention may be effectively used in the development of an improved antibody to enhance the binding affinity of an anti-Trx1 antibody. In addition, the improved antibody of the present invention is effective in improvement of performance of a breast cancer diagnosis kit due to excellent binding affinity for Trx1 and very high sensitivity and specificity, compared to a conventional anti-Trx1 antibody. Further, the accuracy and reliability of breast cancer diagnosis may significantly increase because exceptionally high sensitivity and specificity are exhibited by detecting the monoclonal antibody of the present invention, which specifically binds to Trx1, rather than detecting CA15-3, another conventional breast cancer diagnostic biomarker.

Abstract: Provided is a method for preparing an acrylic acid including: dehydrating a lactic acid aqueous solution in a reaction unit to prepare a reaction product stream; passing the reaction product stream through a cooling unit and a refining unit sequentially and supplying a discharge stream from the refining unit to an acrylic acid separation column; and separating an unreacted lactic acid as a side discharge stream and separating the acrylic acid as an upper discharge stream in the acrylic acid separation column.

Abstract: Provided is a method for preparing an acrylic acid, in which a lactic acid aqueous solution is dehydrated to prepare a reaction product stream, from which by-products are removed using an extraction column, an extractant recovery column, a first separation column, a second separation column, and a refining column to prepare a high-purity acrylic acid.

Abstract: Provided is a method for preparing an acrylic acid including: supplying a lactic acid aqueous solution to a reactor and performing a dehydration reaction to prepare a reaction product including an acrylic acid; supplying a reactor discharge stream including the reaction product to a first cooling tower and supplying an upper discharge stream from the first cooling tower to a second cooling tower; supplying a first acrylic acid aqueous solution stream discharged from a lower portion of the second cooling tower to an extraction column; supplying an upper discharge stream from the extraction column and a second acrylic acid aqueous solution stream discharged from a lower portion of the first cooling tower to a distillation column; and separating the acrylic acid from a lower discharge stream from the distillation column.

Abstract: Provided are a fluorinated compound for patterning a metal or an electrode (cathode), an organic electronic element using the same, and an electronic device thereof, wherein a fine pattern of the electrode is formed by using the fluorinated compound as a material for patterning a metal or an electrode (cathode), without using a shadow mask, and it is possible to more easily apply UDC since it is easy to manufacture a transparent display having high light transmittance.

Abstract: The present disclosure relates to a method for preparing a polyalkylene carbonate. More specifically, provided is a method for preparing a polyalkylene carbonate in which after polymerization of polyalkylene carbonate, a mixture from which unreacted carbon dioxide and residual catalyst have been removed is charged into a stripper to remove the unreacted epoxide compound, and then heat-exchanged before removing the solvent to increase the temperature of the mixture stream to the maximum level, which is subjected to a heating step, following by a solvent removal step, whereby the amount of steam required in the heating step is reduced, side reactions due to unreacted epoxide compounds are prevented, and steam energy can be reduced in the solvent removal step.

Abstract: Provided are a fluorinated compound for patterning a metal or an electrode (cathode), an organic electronic element using the same, and an electronic device thereof, wherein a fine pattern of the electrode is formed by using the fluorinated compound as a material for patterning a metal or an electrode (cathode), without using a shadow mask, and it is possible to more easily apply UDC since it is easy to manufacture a transparent display having high light transmittance.

Abstract: The present invention relates to a method for preparing a polyolefin-polystyrene-based multiblock copolymer having a uniform structure and showing excellent physical properties through continuous type coordination polymerization and batch type anionic polymerization.

Abstract: The present application relates to a process for producing acrylic acid.