Abstract: Provided is a process for producing acrylic acid, the process comprising: (step 1) preparing a first aqueous lactic acid solution by diluting a lactic acid raw material with water; (step 2) heat exchanging the first aqueous lactic acid solution to form a vaporized second lactic acid vapor and an unvaporized third aqueous lactic acid solution; (step 3) including the unvaporized third aqueous lactic acid solution in the aqueous solution of the step 1; and (step 4) supplying and absorbing an absorption liquid to the vaporized second lactic acid vapor to form an absorbed fourth aqueous lactic acid solution and an unabsorbed fifth lactic acid vapor, wherein the absorption liquid is water or an aqueous lactic acid solution.

Abstract: Provided is a process for producing acrylic acid, the process including supplying a lactic acid raw material to an upper portion of a distillation tower; supplying water to a lower portion of the distillation tower; supplying a first lactic acid vapor vaporized in the distillation tower to a reactor; and supplying a second aqueous lactic acid solution not vaporized in the distillation tower to a middle portion of the distillation tower. The process uses a distillation tower instead of a vaporizer, and is capable of preventing formation of a lactic acid oligomer during vaporization of an aqueous lactic acid solution, and, by introducing a concentrated lactic acid raw material to the distillation tower as it is, is capable of producing acrylic acid without a separate dilution device.

Abstract: The present invention relates to a pharmaceutical composite composition for prevention or treatment of diabetes mellitus and at least one disease selected from metabolic diseases associated therewith. The pharmaceutical composition according to the present invention exhibits excellent effects of lowering blood glucose levels, body weight, and blood lipid levels. Therefore, the composition can be advantageously used for preventing or treating diabetes mellitus and at least one disease selected from metabolic diseases associated therewith.

Abstract: Provided is a method for producing acrylic acid, the method including: preparing a reaction product containing acrylic acid by supplying lactic acid to a reactor and performing a dehydration reaction; supplying a reactor discharge stream containing the reaction product to a cooling tower and condensing the result to transfer a lower discharge stream including a condensate to an acrylic acid purification unit and supplying a non-condensate discharged as an upper discharge stream to a distillation tower; and, in the distillation tower, circulating the lower discharge stream containing acrylic acid to the cooling tower, and removing acetaldehyde from the upper discharge stream.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating nonalcoholic fatty liver disease. The pharmaceutical composition according to the present invention exhibits excellent effects of improving lipid metabolism, reducing fat accumulation in liver tissues and inhibiting histological damage caused by inflammation and fibrosis of liver tissues, and thus can be effectively used as a use of preventing or treating nonalcoholic fatty liver disease.

Abstract: The present disclosure is broadly concerned with the field of cancer immunotherapy. For example, the present invention generally relates to an immune cell comprising a genetically engineered antigen receptor that specifically binds to a target antigen and a genetic disruption agent that reduces or is capable of reducing the expression in the immune cell of two genes that weaken the function of the immune cell.

Abstract: Provided are a method for preparing an oligomer and an apparatus for preparing an oligomer. The method for preparing an oligomer includes performing an oligomerization reaction by feeding a feed stream containing a monomer to a reactor; feeding a first discharge stream of the reactor to a first separation device, and feeding a second discharge stream of the reactor to a second separation device; feeding a lower discharge stream of the second separation device to a third separation device; feeding an upper discharge stream containing the monomer of the third separation device to a monomer dissolution device and dissolving the upper discharge stream in a solvent fed to the monomer dissolution device; and feeding a discharge stream of the monomer dissolution device to the reactor.

Abstract: Provided are a method for preparing an oligomer and an apparatus for preparing the same. The method for preparing an oligomer including: supplying a feed stream including a monomer to a reactor to perform an oligomerization reaction; supplying a first discharge stream from the reactor to a first separation device and supplying a second discharge stream from the reactor to a second separation device; recovering the monomer as an upper discharge stream from the second separation device and supplying a lower discharge stream from the second separation device to a third separation device; and supplying an upper discharge stream from the third separation device to the second separation device.

Abstract: The present invention relates to a method for purifying N-substituted maleimide. More particularly, the present invention adopts an evaporation apparatus, which can previously remove impurities having higher boiling points than the N-substituted maleimide after removing an organic solvent from an N-substituted maleimide resulting solution, thereby achieving effects of minimizing the pressure loss and polymerization loss, and obtaining high-purity N-substituted maleimide.

Abstract: A method and an apparatus for preparing an oligomer, the method including supplying a feed stream including a monomer to a reactor to perform an oligomerization reaction, recovering unreacted monomer, and dissolving the recovered unreacted monomer in a solvent in a monomer dissolution device and supplying a discharge stream from the monomer dissolution device to the reactor. The method and the apparatus provide reduced investment costs and improved economic feasibility as there is no need to use a refrigerant at a very low temperature or install a separate compressor to recover and reuse the unreacted monomer in an oligomer production process.

Abstract: Provided are a method for preparing an oligomer and an apparatus for preparing an oligomer. The method for preparing an oligomer includes performing an oligomerization reaction by feeding a feed stream containing a monomer to a reactor; feeding a first discharge stream of the reactor to a first separation device, and feeding a second discharge stream of the reactor to a second separation device; feeding a lower discharge stream of the second separation device to a third separation device; feeding an upper discharge stream containing the monomer of the third separation device to a monomer dissolution device and dissolving the upper discharge stream in a solvent fed to the monomer dissolution device; and feeding a discharge stream of the monomer dissolution device to the reactor.

Abstract: Provided are a method for preparing an oligomer and an apparatus for preparing the same. The method for preparing an oligomer including: supplying a feed stream including a monomer to a reactor to perform an oligomerization reaction; supplying a first discharge stream from the reactor to a first separation device and supplying a second discharge stream from the reactor to a second separation device; recovering the monomer as an upper discharge stream from the second separation device and supplying a lower discharge stream from the second separation device to a third separation device; and supplying an upper discharge stream from the third separation device to the second separation device.

Abstract: A method and an apparatus for preparing an alpha-olefin. The method includes supplying a feed stream including a gaseous ethylene monomer to a monomer dissolution device to dissolve the feed stream in a solvent and form a liquid ethylene monomer, and supplying a feed stream including the liquid ethylene monomer as a discharge stream to a reactor, thereby removing heat of dissolution of the gaseous ethylene monomer outside of the reactor, and decreasing an amount of a refrigerant used in an alpha-olefin production process to improve economic feasibility.

Abstract: The present invention pertains to a pharmaceutical composition for preventing or treating non-alcoholic fatty liver disease, the composition containing G protein coupled receptor 119 (GPR119) ligand as an active ingredient. The pharmaceutical composition according to the present invention exhibits the excellent effects of improving lipid metabolism, reducing fat accumulation in liver tissues, and preventing histological damage caused by inflammation and fibrosis in liver tissues, and can thus be useful in preventing or treating non-alcoholic fatty liver disease.

Abstract: A method and an apparatus for preparing an oligomer, the method including supplying a feed stream including a monomer to a reactor to perform an oligomerization reaction, recovering unreacted monomer, and dissolving the recovered unreacted monomer in a solvent in a monomer dissolution device and supplying a discharge stream from the monomer dissolution device to the reactor. The method and the apparatus provide reduced investment costs and improved economic feasibility as there is no need to use a refrigerant at a very low temperature or install a separate compressor to recover and reuse the unreacted monomer in an oligomer production process.

Abstract: The present invention relates to an energy saving method for separating an unreacted monomer, by which an unreacted monomer may be easily recovered from a mixture solution including an unreacted monomer, and a separation system which is capable of performing the method.

Abstract: The present invention relates to a method for purifying N-substituted maleimide. More particularly, the present invention adopts an evaporation apparatus, which can previously remove impurities having higher boiling points than the N-substituted maleimide after removing an organic solvent from an N-substituted maleimide resulting solution, thereby achieving effects of minimizing the pressure loss and polymerization loss, and obtaining high-purity N-substituted maleimide.

Abstract: The present disclosure relates to a method for preparing a polyalkylene carbonate. More specifically, provided is a method for preparing a polyalkylene carbonate in which after polymerization of polyalkylene carbonate, a mixture from which unreacted carbon dioxide and residual catalyst have been removed is charged into a stripper to remove the unreacted epoxide compound, and then heat-exchanged before removing the solvent to increase the temperature of the mixture stream to the maximum level, which is subjected to a heating step, following by a solvent removal step, whereby the amount of steam required in the heating step is reduced, side reactions due to unreacted epoxide compounds are prevented, and steam energy can be reduced in the solvent removal step.

Abstract: A method and an apparatus for preparing an alpha-olefin. The method includes supplying a feed stream including a gaseous ethylene monomer to a monomer dissolution device to dissolve the feed stream in a solvent and form a liquid ethylene monomer, and supplying a feed stream including the liquid ethylene monomer as a discharge stream to a reactor, thereby removing heat of dissolution of the gaseous ethylene monomer outside of the reactor, and decreasing an amount of a refrigerant used in an alpha-olefin production process to improve economic feasibility.