Abstract: An optical imaging system includes a first lens having a positive refractive power, a second lens, a third lens having a convex object-side surface, a fourth lens, and a fifth lens sequentially disposed from an object side of the optical imaging system toward an imaging plane. A thickness of the fourth lens is greater than a thickness of the fifth lens; a radius of curvature of an object-side surface of the second lens is greater than a radius of curvature of the object-side surface of the third lens; a radius of curvature of an image-side surface of the third lens is greater than a radius of curvature of an image-side surface of the fourth lens; and 0.40<BFL/f is satisfied, where BFL is a distance from an image-side surface of the fifth lens to the imaging plane, and f is a focal length of the optical imaging system.

Abstract: A camera module including a first lens group having a plurality of lenses and disposed fixedly on an optical axis, and a second lens group having a plurality of lenses and movable in an optical axis direction, wherein the first lens group and the second lens group are disposed in sequence from an object side. A distance on the optical axis from an object-side surface of a lens of the second lens group, disposed closest to the object side, to an image-side surface of a lens of the second lens group, disposed closest to an image side is shorter than a distance on the optical axis from an object-side surface of a lens of the first lens group, disposed closest to the object-side, to an image-side surface of a lens of the first lens group, disposed closest to the image side.

Abstract: The present application relates to a respiratory syncytial virus subtype A (RSV-A) recombinant F protein, a polynucleotide encoding the RSV-A recombinant F protein, a nucleic acid construct comprising the polynucleotide, an expression vector comprising the nucleic acid construct, a host cell into which the polynucleotide, the nucleic acid construct, or the expression vector is transformed or transfected, a stabilized trimer formed from the RSV-A recombinant F protein, an immunogenic composition comprising any of the foregoing, and use of any of the forgoing in the preparation of a vaccine for the prevention and/or treatment of respiratory syncytial virus infections. The RSV-A recombinant F protein comprises at least one epitope specific to the pre-fusion F protein, and can form a stable, pre-fusion conformation of F protein trimer. Furthermore, the RSV-A recombinant F protein can be expressed stably in a uniform form and with a significantly increased yield.

Abstract: The present application relates to a respiratory syncytial virus subtype B (RSV-B) recombinant F protein, a polynucleotide encoding the RSV-B recombinant F protein, a nucleic acid construct comprising the polynucleotide, an expression vector comprising the nucleic acid construct, a host cell into which the polynucleotide, the nucleic acid construct, or the expression vector is transformed or transfected, a stabilized trimer formed from the RSV-B recombinant F protein, an immunogenic composition comprising any of the foregoing, and use of any of the forgoing in the preparation of a vaccine for the prevention and/or treatment of respiratory syncytial virus infections. The RSV-B recombinant F protein comprises at least one epitope specific to the pre-fusion F protein, and can form a stable, pre-fusion conformation of F protein trimer. Furthermore, the RSV-B recombinant F protein can be expressed stably in a uniform form and with a significantly increased yield.

Abstract: A camera module is provided. The camera module includes a first lens module including at least one lens disposed in a first optical axis direction, a reflective module including a reflective member and configured to rotate with respect to two rotation axes which are perpendicular each other, and a second lens module including at least one lens disposed in a second optical axis direction and configured to move in the second optical axis direction. The first lens module is configured to be coupled to the reflective module and is configured to rotate together with the reflective module with respect to the two rotation axes which are perpendicular to each other.

Abstract: A camera module includes a lens module including a plurality of lenses having refractive power, a first optical path folding unit disposed on the object side of the lens module and configured to refract or reflect incident light in an optical axis direction of the lens module. Among the lenses constituting the lens module, an effective radius of a lens closest to the first optical path folding unit may have substantially the same size as an effective radius of an exit surface of the first optical path folding unit.

Abstract: An optical imaging system includes a reflective member having a reflective surface for changing a path of light; a first lens group, disposed on a front side of the reflective member, comprising one or more lenses; and a second lens group, disposed on a rear side of the reflective member, comprising a plurality of lenses. Each of the first lens group and the second lens group has positive refractive power. An object-side surface of a frontmost lens disposed closest to an object side, among the one or more lenses of the first lens group, is convex. 0.5<fG1/fG2<2.5 is satisfied, where fG1 is a focal length of the first lens group, and fG2 is a focal length of the second lens group.

Abstract: Described herein are methods such as multi-omic methods for assessing a disease such as cancer. The multi-omic methods may integrate proteomic, transcriptomic, genomic, lipidomic, or metabolomic data. The method screening diseases or disease states. Also described herein are methods for screening for diseases or disease states from biological samples. The methods may include assessing whether a nodule, mass, or cyst is cancerous.

Abstract: Described herein are methods for screening for a disease state. The method may include obtaining multiple data sets and identifying the disease state based on a combination of the data sets. The data sets may include biomolecule measurements obtained by multiple methods, such as through the use of particles and reference biomolecules.

Abstract: An imaging lens system includes an optical path folding member including a forwardmost reflective surface disposed closest to an object side, a rearmost reflective surface disposed closest to an imaging plane, and a rear reflective surface disposed to form an acute angle with the rearmost reflective surface and configured to reflect light reflected by the rearmost reflective surface to the imaging plane, and a first lens group disposed on an object side of the forwardmost reflective surface or an image side of the forwardmost reflective surface, wherein an angle between a first virtual plane including the forwardmost reflective surface and a second virtual plane including the rearmost reflective surface is 15 to 27 degrees.

Abstract: A camera module includes a first lens barrel including a first support portion supporting a lens accommodated in the first lens barrel on an object side of the first lens barrel, and a second lens barrel including a second support portion supporting a lens accommodated in the second lens barrel on an image side of the second lens barrel, wherein the first lens barrel and the second lens barrel are configured to be coupled to each other by a protrusion and a groove.

Abstract: A camera module includes a lens module including a plurality of lenses having refractive power, a first optical path folding unit disposed on the object side of the lens module and configured to refract or reflect incident light in an optical axis direction of the lens module. Among the lenses constituting the lens module, an effective radius of a lens closest to the first optical path folding unit may have substantially the same size as an effective radius of an exit surface of the first optical path folding unit.

Abstract: A lens assembly includes a first D-cut lens and a lens barrel surrounding a portion of a side surface of the first D-cut lens. The side surface of the first D-cut lens includes a linear portion, and the lens barrel is configured to expose at least a portion of the linear portion of the first D-cut lens in a direction perpendicular to an optical axis.

Abstract: An imaging lens system includes an optical path folding member including a forwardmost reflective surface disposed closest to an object side, a rearmost reflective surface disposed closest to an imaging plane, and a rear reflective surface disposed to form an acute angle with the rearmost reflective surface and configured to reflect light reflected by the rearmost reflective surface to the imaging plane, and a first lens group disposed on an object side of the forwardmost reflective surface or an image side of the forwardmost reflective surface, wherein an angle between a first virtual plane including the forwardmost reflective surface and a second virtual plane including the rearmost reflective surface is 15 to 27 degrees.

Abstract: A lens module includes a lens barrel, including a first lens and a second lens arranged along an optical axis, and a spacer disposed between the first lens and the second lens along the optical axis, and defining a hole corresponding to the optical axis and an opening that is open in a direction intersecting the optical axis.

Abstract: A camera module includes a lens module including a plurality of lenses having refractive power, a first optical path folding unit disposed on the object side of the lens module and configured to refract or reflect incident light in an optical axis direction of the lens module. Among the lenses constituting the lens module, an effective radius of a lens closest to the first optical path folding unit may have substantially the same size as an effective radius of an exit surface of the first optical path folding unit.

Abstract: An imaging lens system is provided. The imaging lens system includes a lens group including a plurality of lenses; and an optical path conversion member disposed between the lens group and an imaging plane. The lens group may include a first lens, a second lens, a third lens, and a fourth lens sequentially disposed from an object side toward the imaging plane. The optical path conversion member may reflect light emitted from the lens group two or more times to increase a rear focal length of the lens group (or a distance from an image-side surface of a lens disposed on a rearmost side of the lens group to the imaging plane).

Abstract: A spacer is provided. The spacer includes an opening through which light passes and an internal surface that forms the opening, wherein the internal surface includes a first internal surface having a first curvature portion having a first predetermined curvature and a second internal surface disposed to face the first internal surface in a first direction, perpendicular to an optical axis direction, and having a second curvature portion having a second predetermined curvature, a distance between the first internal surface and the second internal surface is less than a distance between surfaces facing each other in the second direction, intersecting the first direction, and the first curvature portion and the second curvature portion are provided as a pair, corresponding to each other, to form an arc of a circle inscribed on the first internal surface and the second internal surface.

Abstract: An optical imaging system includes a first lens group, a reflective member, and a second lens group sequentially arranged along an optical axis. Each of the first lens group and the second lens group includes a plurality of lenses. The first lens group has positive refractive power. An effective diameter of a first lens, among the plurality of lenses in the first lens group, is largest among the plurality of lenses in the first and second lens groups, and 0<DL1P/TTL<0.25 is satisfied, where DL1P is a distance, on the optical axis, from an object-side surface of the first lens in the first lens group to a first surface of the reflective member, and TTL is a distance, on the optical axis, from the object-side surface of the first lens in the first lens group to an imaging surface.

Abstract: A lens module includes a lens barrel, including a first lens and a second lens arranged along an optical axis, and a spacer disposed between the first lens and the second lens along the optical axis, and defining a hole corresponding to the optical axis and an opening that is open in a direction intersecting the optical axis.