Abstract: The present invention relates to a process for making a compound of formula (I) as described herein Formula (I) comprising reducing a compound of formula (II) as described herein with hydrogen in the presence of a palladium catalyst and a solvent wherein the solvent is a polar, aprotic solvent or a C3-C10 alcohol Formula (II). The present invention further relates to a hydrochloride salt and a monohydrochloride salt of the compound of formula (I) as described herein and to a process for making the same Formula (I).

Abstract: The present invention relates to pharmaceutical combinations comprising a compound of formula I or a pharmaceutically acceptable salt thereof and cyclo(-Tyr-His-Ala-Cys-Ser-Ala-DPro-Dab-Arg-Tyr-Cys-Tyr-Gln-Lys-DPro-Pro-) having a disulfide bond between Cys4 and Cys1 11 or a pharmaceutically acceptable salt thereof and their use in a method for the prevention, delay of progression or treatment of cancer in a subject.

Abstract: A frictional damper is designed with a tubular housing having a longitudinal axis, with a tappet, which is displaceable in the housing along the longitudinal axis and is led out at an open end of the housing, with a frictional element lying against the tappet and with a cap attached to the open end of the housing with axial prestressing relative to the longitudinal axis.

Abstract: A tenter-clip carriage for a stretching system comprises a longitudinal direction (LR) and a transverse direction and a clip body having a clamping device. The tenter-clip carriage comprises fastening portions in order to fasten the tenter-clip carriage to a partial chain portion of a conveyor chain arrangement of the stretching system. The tenter-clip carriage comprises at least one stabilising roller or at least one stabilising sliding element. The at least one stabilising roller or the at least one stabilising sliding element is, by means of a guide device: a) held directly on the tenter-clip carriage; or b) held indirectly on the tenter-clip carriage via a pin that connects two chain segments of the partial chain portion of the conveyor chain arrangement to one another and, specifically, unaffected by the feed and drive forces acting on the tenter-clip carriage or the partial chain portion to move the tenter-clip carriage and/or the partial chain portion.

Abstract: A method of forming an electrical contact and a method of forming a chip package are provided. The methods may include arranging a metal contact structure including a non-noble metal and electrically contacting the chip, arranging a packaging material, and a protective layer including or essentially consisting of a portion formed at an interface between a portion of the metal contact structure and the packaging material, wherein the protective layer may include a noble metal, wherein the portion of the protective layer may include a plurality of regions free from the noble metal, and wherein the regions free from the noble metal may provide an interface between the packaging material and the non-noble metal of the metal contact structure.

Abstract: In various embodiments, a method of forming an electrical contact is provided. The method may include depositing, by atomic layer deposition, a passivation layer over at least a region of a metal surface, wherein the passivation layer may include aluminum oxide, and electrically contacting the region of the metal surface with a metal contact structure, wherein the metal contact structure may include copper.

Abstract: An assembly press for producing an insulating glass element with two panes includes: two press elements arranged opposite each other with a working chamber defined by a spacing therebetween, the spacing being adjustable in a first direction to press together the panes; and a conveying device to transport the panes into and out of the working chamber in a second direction perpendicular to the first direction, at least one of the press elements being adjustable in a third direction perpendicular to the first and second directions. The conveying device comprises first and second drivable conveying elements respectively including first and second support mechanisms to respectively support lower faces of the two panes during transport in a first and second transport planes. The first and second conveying elements are adjustable independently of each other such that the transport planes are located at different positions in the third direction.

Abstract: An electrically driven trolley combination for an aircraft cabin with an independently usable, manually movable trolley and an electrical operating apparatus. The trolley has a base section, a main section extending from the base section, and wheels with the trolley supported on a cabin floor by the wheels and manually movable over the cabin floor being pushed or pulled. The electrical operating apparatus can be detachably coupled to the trolley and has a frame, a driveable rolling device on the frame and by which the electrical operating apparatus can be supported on a cabin floor and rolled, a coupling apparatus on the frame for detachably coupling the electrical operating apparatus to the trolley and having an engagement section and a movement section, the engagement section being selectively movable between a first position and a second position by the movement section, an electrical drive device, and a control device.

Abstract: Disclosed is a method that includes: providing semiconductor dies, each of the semiconductor dies having a thinner active region surrounded by a thicker inactive region so that each of the semiconductor dies has a first cavity vertically aligned with the thinner active region and laterally surrounded by the thicker inactive region; providing a metal carrier having connection parts secured to the metal carrier, each of the connection parts dimensioned to fit within the first cavity of one of the semiconductor dies; inserting each of the connection parts of the metal carrier into the respective first cavity of the corresponding semiconductor die; after the inserting, attaching the metal carrier to the semiconductor dies; and after the attaching, singulating the metal carrier so that each of the connection parts of the metal carrier remains attached to the corresponding semiconductor die.

Abstract: A method for ascertaining a setpoint value for a manipulated variable for activating a low-pressure pump in a fuel supply system for an internal combustion engine, including a high-pressure accumulator and a high-pressure pump including a volume control valve, the low-pressure pump being activated in such a way that a pressure provided by the low-pressure pump is reduced across multiple intake phases, in which fuel delivered by the low-pressure pump is sucked in by the high-pressure pump via the volume control valve, the volume control valve being at least temporarily held in a closed position during each of the multiple intake phases, in which it may be opened from a side facing the low-pressure pump, and the setpoint value being ascertained, taking into account an activating value of the manipulated variable, in which a drop in the delivery rate of the high-pressure pump is detected.

Abstract: A method for ascertaining a setpoint value for a manipulated variable for the actuation of a low-pressure pump in a fuel-supply system for an internal combustion engine having a high-pressure accumulator and a high-pressure pump, the high-pressure pump being operated in a full delivery mode, and the low-pressure pump being actuated so that a pressure provided by the low-pressure pump is reduced, and the setpoint value at which a dip in a delivery quantity of the high-pressure pump is detected is ascertained while taking into account an actuation value of the manipulated variable.

Abstract: A fuel distributor, which is in particular used as a fuel distribution rail for mixture-compressing, spark-ignited internal combustion engines, including a base body, at which at least one high-pressure inlet and multiple high-pressure outlets are provided. An insert element is furthermore provided that is situated in an interior of the base body. In the interior, the insert element separates an inflow area, which extends from the high-pressure inlet to the high-pressure outlets, at least essentially from a damping area. The insert element is designed as a thin-walled insert element that forms a divider extending through the interior at least from the high-pressure inlet to the high-pressure outlets.

Abstract: A heat exchanger for a fuel cell system, in particular in a vehicle, includes a gas section for at least one gas and one cooling fluid section for cooling the at least one gas, a housing, and a cooler matrix which is arranged in the housing and in which the cooling fluid section is configured, where the cooler matrix forms a multiplicity of cavities which produce the gas section, at least one gas inlet on the housing, at least one partition in the cooler matrix for dividing the gas section into at least two flows, with the result that the two flows can be cooled by way of the same cooling fluid section, and at least two gas outlets on the housing, where each flow opens into a dedicated gas outlet.

Abstract: An accommodation system for an accommodation space for storing rollable containers in a vehicle. After a front container, which is arranged at the insertion opening, has been removed in the conventional manner, it is possible, through the use of the accommodation system, to remove the rear container which is arranged considerably spaced apart from the insertion opening in the interior of the accommodation space. For this purpose, a rail system is provided in the floor region of the accommodation space. A transfer plate is movable on the rail system in the floor region of the accommodation space and can assume a storage position and a removal position for the rear container.

Abstract: A stowage and removal system is provided for a receiving space for container storage in a vehicle. It has a rail system in a bottom region of the receiving space, on which a transfer plate can be moved and which can assume a storage position and an entry and removal position for the container. The container storage position is provided with its rear wall in a region of the receiving space rear wall. The entry and removal position is provided in the region of a push-in opening, lying opposite the rear wall, for pushing in and removing a container into or from the receiving space.

Abstract: A stowage and removal system for an accommodation space for storing rollable containers in a vehicle is provided. It preferably has a rail system in the floor region of the accommodation space, on which rail system a transfer plate is movable, which transfer plate can assume a storage position and an insertion and removal position for the container. The storage position of the container is provided with its rear wall in the region of the rear wall of the accommodation space. The insertion and removal position is provided in the region of an insertion opening, arranged oppositely in relation to the rear wall, for the insertion and removal of a container into the accommodation space.

Abstract: A fuel cell having an anode-cathode stack includes at least one active surface layer formed by a first channel structure with a first and at least one second channel for conducting a first fluid over the at least one active surface layer of the anode-cathode stack. A first distributor structure for distributing the first fluid into the first and the at least one second channel of the channel structure is provided. The first distributor structure is configured with a first surface region assigned to the first channel and with a second surface region assigned to the second channel. The two surface regions are configured with a flow resistance of differing magnitude for the first fluid distributed in the first distributor structure.

Abstract: The present description provides a water-reducible or water-dispersible coating system that can be used to form a durable, corrosion-resistant protective coating on a wide range of substrates. The coating system includes an alkyd resin prepared from a polyester feedstock that includes post-consumer recycled PET and a waste cooking oil feedstock. Methods for preparing the coating system and articles coated with the coating system are also described.

Abstract: A piston housing unit includes a housing with a longitudinal axis, a piston rod that is displaceable, in particular along the longitudinal axis and/or around the longitudinal axis, a guide/damping unit for guiding and damping the displacement of the piston rod.

Abstract: A piston housing unit comprises a housing with a longitudinal axis, a piston rod that is displaceable, in particular along the and/or around the longitudinal axis, a guide/damping unit for guiding and damping the displacement of the piston rod.