Patents by Inventor Michael A. Brehm
Michael A. Brehm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8125709Abstract: The present invention is directed to a controllable microscope illumination within a microscope system by which all essential contrasting methods in microscopy can be realized. The illumination device according to the invention comprises a plurality of individual light sources which can be regulated with respect to brightness, wherein these individual light sources are formed as unit cells and form a luminous surface by a periodic arrangement. In an advantageous arrangement, imaging optics are associated with each individual light source in order to magnify the image of the source surface of the individual light source so that the images of the source surfaces of adjacent individual light sources touch. Illumination variants for all of the essential contrasting methods in microscopy can be generated by way of the proposed solution. The proposed LED illumination is electronically switchable, can be regulated with respect to brightness, supplies all colors, is long-lasting and economical.Type: GrantFiled: June 22, 2006Date of Patent: February 28, 2012Assignee: Carl Zeiss MicroImaging GmbHInventors: Lutz Hoering, Andreas Nolte, Michael Brehm, Mario Sondermann
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Patent number: 8115164Abstract: A calibration device for managing a variety of performance tests and/or calibration tasks in a laser scanning microscope. The calibration device, which has focusing optics and a test structure arranged in the focal plane of the focusing optics, with structural elements detectable in reflected and/or transmitted light aligned to each other in a common mounting, can be switched into the microscope beam path in a laser scanning microscope, so that the pupil of the focusing optics coincides with the objective pupil of the laser scanning microscope or lies in a plane conjugated to it.Type: GrantFiled: January 29, 2009Date of Patent: February 14, 2012Assignee: Carl Zeiss MicroImaging GmbHInventors: Ralf Netz, Wolfgang Bathe, Joerg Steinert, Werner Kleinschmidt, Ingo Fahlbusch, Michael Brehm
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Patent number: 7706076Abstract: An optical system for arranging between a light source and a field diaphragm in an illumination beam path of a microscope comprises n imaging optical elements with focal lengths fi and Abbe numbers ?i (i=1, . . . , n). The following relationship is met for the optical system: ? i = 1 n ? h i f i · v i ? 0.07 , where hi is one half of the bundle diameter of a bundle of light rays proceeding from a point of the light source at the entrance to the imaging optical element i.Type: GrantFiled: September 21, 2005Date of Patent: April 27, 2010Assignee: Carl Zeiss MicroImaging GmbHInventors: Michael Brehm, Rolf Wartmann
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Publication number: 20100014157Abstract: The invention is directed to a multispectral illumination device for a microscope or for a reader. According to the invention, the illumination device comprises at least three receptacle positions for lighting modules and at least one receptacle position for coupling modules, the mechanical devices for connecting the lighting modules or coupling modules at the receptacle positions to the illumination device being designed in such a way that the lighting modules or coupling modules can be easily changed. Further, the receptacle positions are arranged in such a way that, with suitable selection of the lighting modules and coupling modules, all individual spectra of the lighting modules in a total spectrum are available simultaneously at the output of the illumination device.Type: ApplicationFiled: October 6, 2007Publication date: January 21, 2010Inventors: Andress Nolte, Matthias Kramer, Michael Brehm, Christian Boeker
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Publication number: 20090224694Abstract: The present invention is directed to a controllable microscope illumination within a microscope system by which all essential contrasting methods in microscopy can be realized. The illumination device according to the invention comprises a plurality of individual light sources which can be regulated with respect to brightness, wherein these individual light sources are formed as unit cells and form a luminous surface by a periodic arrangement. In an advantageous arrangement, imaging optics are associated with each individual light source in order to magnify the image of the source surface of the individual light source so that the images of the source surfaces of adjacent individual light sources touch. Illumination variants for all of the essential contrasting methods in microscopy can be generated by means of the proposed solution. The proposed LED illumination is electronically switchable, can be regulated with respect to brightness, supplies all colors, is long-lasting and economical.Type: ApplicationFiled: June 22, 2006Publication date: September 10, 2009Inventors: Lutz Höring, Andreas Nolte, Michael Brehm, Mario Sondermann
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Publication number: 20090224174Abstract: A calibration device for managing a variety of performance tests and/or calibration tasks in a laser scanning microscope. The calibration device, which has focusing optics and a test structure arranged in the focal plane of the focusing optics, with structural elements detectable in reflected and/or transmitted light aligned to each other in a common mounting, can be switched into the microscope beam path in a laser scanning microscope, so that the pupil of the focusing optics coincides with the objective pupil of the laser scanning microscope or lies in a plane conjugated to it.Type: ApplicationFiled: January 29, 2009Publication date: September 10, 2009Inventors: Ralf Netz, Wolfgang Bathe, Joerg Steinert, Werner Kleinschmidt, Ingo Fahlbusch, Michael Brehm
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Publication number: 20090225408Abstract: An optical system for arranging between a light source and a field diaphragm in an illumination beam path of a microscope comprises n imaging optical elements with focal lengths fi and Abbe numbers ?i (i=1, . . . , n). The following relationship is met for the optical system: ? i = 1 n ? h i f i · v i ? 0.07 , where hi is one half of the bundle diameter of a bundle of light rays proceeding from a point of the light source at the entrance to the imaging optical element i.Type: ApplicationFiled: September 21, 2005Publication date: September 10, 2009Inventors: Michael Brehm, Rolf Wartmann
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Patent number: 7430075Abstract: A condenser arrangement for brightfield illumination and/or darkfield illumination for optical microscopes comprises in a housing basic optics having at least one lens, at least one front optics which can be inserted into the illumination beam path in front of the basic optics, and means for inserting the front optics into the illumination beam path of the microscope. A first swiveling arm and a second swiveling arm are swivelably arranged at the housing of the condenser. The first swiveling arm carries first front optics with a high aperture for brightfield illumination and the second swiveling arm carries second front optics for darkfield illumination. The two swiveling arms are arranged at a defined distance from the shared basic optics of the condenser in direction of the optical axis of the illumination beam path. An aperture iris diaphragm is provided on the object side in front of the basic optics and is opened when the cardioid optics are inserted.Type: GrantFiled: July 29, 2005Date of Patent: September 30, 2008Assignee: Carl Zeiss MicroImaging GmbHInventors: Peter Dietrich, Michael Brehm, Heino Heise
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Publication number: 20080049313Abstract: The invention is directed to illumination optics for an optical device for observing a sample, particularly for TIRF microscopy (Total Internal Reflection Fluorescence Microscopy), wherein the sample is positioned on the side of a carrier glass remote of the illumination optics and the illumination light exiting from the illumination optics is shaped into an illumination beam bundle which encloses an angle not equal to 90° with the normal to the surface of the carrier glass. According to the invention, the illumination optics of the type mentioned above comprise at least two optically active elements which influence the shape and direction of the illumination beam bundle and which are arranged outside of the detection beam path that guides light coming from the sample to a detector. The optically active elements are preferably constructed as annular lenses and are arranged concentrically around the detection beam path.Type: ApplicationFiled: August 24, 2007Publication date: February 28, 2008Inventors: Michael Brehm, Werner Kleinschmidt, Jan Thirase
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Publication number: 20070041109Abstract: The invention is directed to a darkfield illumination system and is applicable in transmitted light microscopy and in incident light microscopy. A combination with a first, segmented mirror and a second, aspherical mirror is proposed for the purpose of uniform illumination of the large object fields occurring at low magnifications.Type: ApplicationFiled: March 10, 2004Publication date: February 22, 2007Inventors: Michael Brehm, Ingo Fahlbusch, Heino Heise, Werner Kleinschmidt, Anke Vogelsang
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Patent number: 7042638Abstract: The invention is directed to a device for coupling light into the beam path of a microscope. Laser light is directed to the preparation in the field diaphragm plane through an in-coupling light-conducting fiber constructed as a slide. The invention is particularly suitable for the TIRF method.Type: GrantFiled: July 3, 2003Date of Patent: May 9, 2006Assignee: Carl Zeiss Jena GmbHInventors: Matthias Gonschor, Carsten Hoyer, Michael Brehm
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Publication number: 20060023301Abstract: A condenser arrangement for brightfield illumination and/or darkfield illumination for optical microscopes comprises in a housing basic optics having at least one lens, at least one front optics which can be inserted into the illumination beam path in front of the basic optics, and means for inserting the front optics into the illumination beam path of the microscope. A first swiveling arm and a second swiveling arm are swivelably arranged at the housing of the condenser. The first swiveling arm carries first front optics with a high aperture for brightfield illumination and the second swiveling arm carries second front optics for darkfield illumination. The two swiveling arms are arranged at a defined distance from the shared basic optics of the condenser in direction of the optical axis of the illumination beam path. An aperture iris diaphragm is provided on the object side in front of the basic optics and is opened when the cardioid optics are inserted.Type: ApplicationFiled: July 29, 2005Publication date: February 2, 2006Inventors: Peter Dietrich, Michael Brehm, Heino Heise
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Publication number: 20040047032Abstract: The invention is directed to a device for coupling light into the beam path of a microscope. Laser light is directed to the preparation in the field diaphragm plane through an in-coupling light-conducting fiber constructed as a slide. The invention is particularly suitable for the TIRF method.Type: ApplicationFiled: July 3, 2003Publication date: March 11, 2004Inventors: Matthias Gonschor, Carsten Hoyer, Michael Brehm
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Patent number: 6381306Abstract: A system and method for generating service quality statistics for a communications network is disclosed. Network monitors capture messages in a communications network, such as an SS7 network, and correlate related messages into records. The records are filtered using a call detail record profile to create call detail records which are provided to an statistics server. The statistics server generates certain statistics for the message records and stores the statistics to a database. A report application recalls the statistics from the database and presents statistics in a reporting format configured by the user. The reports indicate the statistical performance of network providers for selected called or calling telephone numbers or for selected services.Type: GrantFiled: June 8, 1998Date of Patent: April 30, 2002Assignee: Inet Technologies, Inc.Inventors: Gerald Ray Lawson, Chad Daniel Harper, Grant Michael Brehm, Gaurang S. Kalyanpur
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Patent number: 6359976Abstract: A system and method for monitoring service quality using Call Detail Records (CDR) in a communications network, such as a Signaling System No. 7 (SS7) network, is disclosed. Network monitors capture substantially all signaling units in the SS7 network generate a complete record for all calls, transactions and other communications over the network. Users configure CDR profiles that are used to filter the records. A CDR application filters the records by parsing out signaling unit components that have been selected by the user in the CDR profile. The selected message components are then formatted into a CDR record, which is sent to an external system that generates certain statistics for the message records and stores the statistics to a database. A report application recalls the statistics from the database and presents statistics in a reporting format configured by the user.Type: GrantFiled: September 14, 1999Date of Patent: March 19, 2002Assignee: Inet Technologies, Inc.Inventors: Gaurang S. Kalyanpur, Chad Daniel Harper, Grant Michael Brehm, Chunchun Jonina Chan
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Patent number: 4298556Abstract: A fiber reinforcement is positioned on the female part of a matched die, and a reactive foaming mixture of polyol and isocyanate is placed on the reinforcement, the male part of the die set being then closed on the female part so as to compress the reinforcement and holding the die parts together while the mixture's foaming reaction occurs. So that the reinforcement can comprise finer than usual individual fiber thicknesses and be compressed more than usual by closing of the die while still filling all the voids between the fibers of the reinforcement with the foam produced by the mixture's reaction, from 5 to 30% by weight of a neutral ester having a boiling temperature higher than the foaming reaction temperature of the mixture, is initially added to the mixture before it is placed on the reinforcement and prior to closing of the die.Type: GrantFiled: December 13, 1979Date of Patent: November 3, 1981Assignee: Firma Carl FreudenbergInventors: Peter W. Rutsch, Michael Brehm
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Patent number: 4132754Abstract: In the production of a polyurethane foam by supplying two or more components to a machine, mixing said components, extruding the mixture to form a foaming mass, subsequently discontinuing supply and extrusion, rinsing the machine, and subsequently resuming supply and extrusion, the improvement which comprises effecting said rinsing with a rinsing agent having the approximate weight compositionWater: 70-80 partsSorbitol: 25-18 partsEmulsifier: 5-2 partsType: GrantFiled: February 11, 1977Date of Patent: January 2, 1979Assignee: Firma Carl FreudenbergInventors: Kurt Weber, Michael Brehm