Abstract: The present disclosure provides polymer conjugates comprising a polymer and an agent the agent linked to the polymer via a linking group containing a cleavable moiety.

Abstract: Systems and apparatus for receiving golf balls include an apparatus including: a body having an ingress and an egress for golf balls passing through the body, wherein each of the golf balls includes a radio frequency identification tag; at least one antenna of a radio frequency identification reader, the at least one antenna arranged with respect to the body to receive information from the golf balls for identification of the golf balls; and multiple protrusions located within the body, the multiple protrusions being positioned with respect to each other in a Galton configuration that both (i) impedes the golf balls from passing through the body without being read by the radio frequency identification reader, and (ii) allows the golf balls to pass through the body without jamming therein.

Abstract: A method for delivering one or more oral care active agents to a mammal's mouth using a nonwoven web of filaments and/or fibers containing one or more oral care active agents that are releasable from the filaments and/or fibers is provided.

Abstract: The present invention relates to novel compounds and methods for the manufacture of inhibitors of deubiquitylating enzymes (DUBs). In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase 30 or ubiquitin specific peptidase 30 (USP30).

Abstract: A representative spacecraft system includes a launch vehicle elongated along a launch vehicle axis and having at least one stage carrying a corresponding rocket engine. The representative system further includes an annular support structure carried by the at least one stage and positioned to support a cargo spacecraft having a service module and a cargo module. The cargo module of the cargo spacecraft is positioned along the launch vehicle axis in a direction distal from the support structure, and at least a portion of the service module of the cargo spacecraft positioned within an annulus of the support structure.

Abstract: Freshening composition having at least 70% by weight of the freshening composition of water, a perfume, wherein the perfume includes at least 60% by weight of the perfume, Perfume Raw Materials (“PRMs”) having C log P greater than 1; and at least 0.0015% by weight of the freshening composition of an alkoxylated aromatic.

Abstract: Clustering a plurality of client devices running an application as a function of a data structure such that the plurality of client devices are each assigned a cluster. Client devices having similar performance metrics are assigned the same cluster. An operation of the application is modified as a function of the performance metrics of the client device. The modification of application operation is performed by turning certain features of the application on and off using a rule based on device cluster.

Abstract: Disclosed is a mobile event streaming system that receives customer application lifecycle and user events including a message, event source and a destination then processes data for consumption by one or more customers, generating a secure data stream and sending the processed data over the generated data stream. An example system for receiving, processing, and delivering customer application lifecycle and user engagement data includes a server system having at least one processor, memory and a network interface where the memory stores program instructions for receiving, storing, processing and transmitting messages via the network interface. The mobile event streaming system may be a distributed content delivery service wherein the content delivered via the service is processed. Processing the data comprises the addition of metadata, one or more identifiers such as user, and event identifiers including predictions of future user engagement to enable real-time data consumption by customers.

Abstract: A system for identifying irregularities in behaviors of a non-human animal, the system comprising a processing circuitry configured to: provide a behavioral baseline including first information on regular behaviors of the non-human animal over a given period of time when no irregularities occur; obtain data on a series of consecutively identified behaviors of the non-human animal identified over a second period of time; perform an action upon the data not complying with the behavioral baseline, thereby indicating an irregularity in the non-human animal behavior.

Abstract: A wing lock and deployment apparatus for an air launched vehicle includes a driver acted on by a single linear actuation event. The disclosed wing lock and deployment apparatus is capable of unlocking deployable wings of an air launched vehicle, deploying deployable wings of the air launched vehicle from a stored position, and locking deployable wings of the air launched vehicle in a deployed position in sequential order with the one single linear actuation event.

Abstract: Systems and methods for providing a communications and relative positioning capability using frequency-modulated continuous-wave radar installed on multiple mobile and/or stationary objects, providing secure/reliable determination of signal origin from a select one of a plurality of geographically mobile machines, equipment, devices, or systems and subsequent selective establishment/facilitation of direct/deterministic/reliable communication therewith.

Abstract: A method and apparatus for authenticating a user commerce account associated with a merchant of a commerce platform are described. The method may include initiating authentication of the user commerce account associated with the merchant of the commerce platform from a commerce platform user interface of a user device, the user commerce account established for a user of the merchant. The method may also include sending an electronic message to a mobile device associated with the user account at the commerce platform, wherein the electronic message comprises an authentication code, and receiving the authentication code from the commerce platform user interface. Furthermore, the method may include generating an authentication key for the mobile device in response to matching the received authentication code with the sent authentication code and receiving a cookie provided from the commerce platform to the mobile device.

Abstract: This disclosure relates to combination therapies targeting two or all of PD-1, TIM-3, and LAG-3 using antibodies specific for these targets in patients who are in need of enhanced immunity. Also included in the disclosure are compositions useful in the therapies. The therapies are useful in treating diseases such as cancers.

Abstract: Therapeutic modalities are provided involving the use of specific repertoirs of PRR ligands to ameliorate immune dysregulation in a perioperative period. In effect, innate immune system signaling is provoked in the perioperative period so as to facilitate a targeted immune response following surgery. Subjects may accordingly be treated with immunogenic formulations tailored to a specific target tissue to treat a subject during the perioperative period surrounding surgery to remove a solid tumor, where the target tissue is the site of the tumor or a characteristic site of metastasis for the cancer.

Abstract: A gesture-based wake process for an AR system is described herein. The AR system places a hand-tracking input pipeline of the AR system in a suspended mode. A camera component of the hand-tracking input pipeline detects a possible visual wake command being made by a user of the AR system. On the basis of detecting the possible visual wake command, the AR system wakes the hand-tracking input pipeline and places the camera component in a fully operational mode. If the AR system, using the hand-tracking input pipeline, verifies the possible visual wake command as an actual wake command, the AR system initiates execution of an AR application.

Abstract: A mechanism for generating a partially denoised image. A residual noise image, obtained by processing an image using a convolutional neural network, is weighted. The blending or combination of the weighted residual noise image and the (original) image generates the partially denoised image.

Abstract: A data processing apparatus includes control flow prediction circuitry that generates a control flow prediction in respect of a group of one or more instructions. Storage circuitry used by the control flow prediction circuitry stores data in association with groups of instructions used to generate the control flow prediction for each of the groups of instructions. Control flow prediction update circuitry inserts new data into the storage circuitry in association with a new group of one or more instructions in dependence on one or more conditions being met when a miss occurs for the group of one or more instructions in the storage circuitry.

Abstract: Systems and methods are provided herein for minimizing retinal exposure to flash during image gathering for diagnosis. In an embodiment, a system captures a plurality of retinal images of different retinal regions. The system determines that a first portion of a first image does not meet a criterion while a second portion of the first image does meet the criterion, identifies a portion of the retina depicted in the first portion that does not meet the criterion, and determines whether the portion of the retina is depicted in a third portion of a second image and whether the third portion meets the criterion. Responsive to determining that the third portion meets the criterion, the system performs the diagnosis. Responsive to determining that the portion of the retina is not depicted in the second image, the system captures an additional image of the retinal region.

Abstract: A vacuum exhaust system includes a plurality of turbo pumps that evacuate a plurality of vacuum chambers. A plurality of chamber valves are positioned between the turbo pumps and the plurality of vacuum chambers. A plurality of branch channels are each connected to a corresponding exhaust of the plurality of turbo pumps and a main channel is formed from a confluence of the branch channels. A booster vacuum pump is connected to the main channel. A backing vacuum pump is connected to an exhaust of the booster vacuum pump. A plurality of bypass channels, each having a valve, provide a fluid communication path between at least some of the plurality of vacuum chambers and the booster vacuum pump.

Abstract: A system for dispensing flame retardant foam on the exterior of a structure. The structure has an opening that enables distribution of flame retardant foam onto the roof. The system includes a foam distribution system having a foam expansion chamber and a roof plenum for delivery through the roof opening. Foam solution and compressed air are combined in a conduit and supplied to the foam expansion chamber. The structure may have at least one wall. In that case, the system may have a wall plenum for delivery of flame retardant foam from the foam expansion chamber through a first wall-associated opening. Each such wall will have an opening associated with the wall that enables distribution of flame retardant foam onto that wall.