Abstract: Described herein are methods of treatment of stroke and traumatic brain injury comprising administration of a CRAC channel inhibitor.

Abstract: Described herein are methods of treatment of stroke and traumatic brain injury comprising administration of a CRAC channel inhibitor.

Abstract: Techniques for optimizing window move actions for a remoted application are provided, where the remoted application has an application window running within a remote desktop of a server system, and where the application window is made accessible to a user of a client system in the form of a client-side application window displayed in a client desktop of the client system. In one embodiment, the client system can receive from the server system a notification that the application window has begun moving in the remote desktop, and can determine that the user is currently entering one or more input commands for moving the client-side application window in the client desktop. The client system can further send a command to the server system for stopping the movement of the application window in the remote desktop, such that the application window is fixed in a stationary position.

Abstract: Techniques for optimizing window move actions for a remoted application are provided, where the remoted application has an application window running within a remote desktop of a server system, and where the application window is made accessible to a user of a client system in the form of a client-side application window displayed in a client desktop of the client system. In one embodiment, the client system can receive from the server system a notification that the application window has begun moving in the remote desktop, and can determine that the user is currently entering one or more input commands for moving the client-side application window in the client desktop. The client system can further send a command to the server system for stopping the movement of the application window in the remote desktop, such that the application window is fixed in a stationary position.

Abstract: Described herein are methods of treatment of stroke and traumatic brain injury comprising administration of a CRAC channel inhibitor.

Abstract: A flexible compression apparatus for seating the bead of a tubeless tire onto a rim and a method of using the apparatus. The flexible compression including: a circular spiral flexible band having a first terminal edge wound on an exterior surface of the flexible band and a second terminal edge wound on an inner surface of the flexible band; one or more straps in contact with the exterior surface of the flexible band and running parallel to the flexible band, said one or more straps each having a secured end and a terminal end, wherein the secured end of the one or more straps is affixed to the flexible band; and one or more tightening mechanisms for receiving the terminal end(s) of the strap(s).

Abstract: Compositions and methods related to the amelioration of pancreatitis through the pharmaceutical manipulation of calcium signaling are disclosed. Such compositions and methods may be used to ameliorate symptoms of acute or chronic pancreatitis or to reduce the chance or severity of pancreatitis in an individual at risk of the condition. In other embodiments, disclosed herein are compositions and methods related to the amelioration of viral diseases through the pharmaceutical manipulation of calcium signaling. In further embodiments, disclosed herein are compositions and methods related to the amelioration of Th17-induced diseases through the pharmaceutical manipulation of calcium signaling.

Abstract: Systems and methods for optimizing hardware resource utilization when processing variable-precision data are provided. Application data objects are processed using either a central processing unit (CPU) or the relatively lower precision data processing requirements of a dedicated math processing unit, e.g., a graphics processing unit (GPU), based on a level of precision determined for each application data object. The level of precision is used to calculate at least one bounding value for each application data object. The bounding value is compared to a selected precision threshold in order to determine whether the application data object can be processed by the GPU at a relatively lower level of precision without an undesirable loss of computational precision.

Abstract: Aspects described herein are concerned with automatically validating spatial features of a spatial dataset. One solution is built upon a database server which performs a decomposition of the features' geometries into line segments, after which, sets of line segments are compared to detect errors in the dataset. The decomposition of features geometries into line segments results in a reduction of processing time with a simultaneous increase of precision. The method not only generates new intermediate database structures for detection of topological errors but is also complemented by a clearance process that can lead to the automatic repair of topological errors. The clearance process identifies topological errors and provides modifications to the previously identified line segments such that a modified set of line segments overcomes the conditions that led to the error state. The changes to the data set can be applied automatically after displaying them as an overlay for a predefined amount of time.

Abstract: Systems and methods for optimizing hardware resource utilization when processing variable-precision data are provided. Application data objects are processed using either a central processing unit (CPU) or the relatively lower precision data processing requirements of a dedicated math processing unit, e.g., a graphics processing unit (GPU), based on a level of precision determined for each application data object. The level of precision is used to calculate at least one bounding value for each application data object. The bounding value is compared to a selected precision threshold in order to determine whether the application data to object can be processed by the GPU at a relatively lower level of precision without an undesirable loss of computational precision.

Abstract: A valve assembly includes a plenum having first, second, and third air source ports, a flapper valve assembly pivotally movable between a first position, where the first air source port is closed by the flapper valve assembly and the second and third air source ports are open and in fluid communication, and a second position, where the second air source port is closed by the flapper valve assembly and the first and third air source ports are open and in fluid communication and a method of controlling fluid flow via a valve assembly.

Abstract: A valve assembly includes a plenum having first, second, and third air source ports, a flapper valve assembly pivotally movable between a first position, where the first air source port is closed by the flapper valve assembly and the second and third air source ports are open and in fluid communication, and a second position, where the second air source port is closed by the flapper valve assembly and the first and third air source ports are open and in fluid communication and a method of controlling fluid flow via a valve assembly.

Abstract: Techniques for optimizing window move actions for a remoted application are provided, where the remoted application has an application window running within a remote desktop of a server system, and where the application window is made accessible to a user of a client system in the form of a client-side application window displayed in a client desktop of the client system. In one embodiment, the client system can receive from the server system a notification that the application window has begun moving in the remote desktop, and can determine that the user is currently entering one or more input commands for moving the client-side application window in the client desktop. The client system can further send a command to the server system for stopping the movement of the application window in the remote desktop, such that the application window is fixed in a stationary position.

Abstract: There is provided a fiber optic scribing tool having a self-contained internal light source. The internal light source is coupled via one or more optical fibers to a rear edge of a transparent or translucent scribing blade removably inserted in a chuck of the illuminated fiber optic scribing tool. Typically an LED light source is used. An internal power source is disposed within a chuck receiver, for example one or more disposable or rechargeable batteries. If rechargeable batteries are selected, a connector is provided on an external surface of the scribing tool to allow the internal battery(s) to be recharged. A switch is provided to selectively turn the light source on and off. In alternate configurations, a clip-on external light source is provided for adding to an existing prior art fiber optic scribing tool. In another embodiment, a stop is positioned on a lower surface of the scribing blade.

Abstract: The present invention provides T cell receptors (TCRs) having the property of binding to SLLMWITQC-HLA-A*0201, the SLLMWITQC SEQ NO:126 peptide being derived from the NY-ESO-1 protein which is expressed by a range of tumour cells. The TCRs have a KD for the said peptide-HLA complex of less than or equal to 1 ?M and/or have an off-rate (koff) of 1×10?3 S?1 or slower.

Abstract: A reaction container has contains an amount of a water reactive material and a volume of water within the confined space of its interior. The water reactive material, which contains aluminum, is formed as two separate and spaced apart portions. The water is located between the two portions of the water reactive material. A detonation mechanism, which is configured to mix the amount of water reactive material and the volume of water, is provided in communication with each portion of the water reactive material. The volume of water and the aluminum in the water reactive material are stoichiometrically balanced.

Abstract: A white light emitting lamp is disclosed comprising a solid state ultra violet (UV) emitter that emits light in the UV wavelength spectrum. A conversion material is arranged to absorb at least some of the light emitting from the UV emitter and re-emit light at one or more different wavelengths of light. One or more complimentary solid state emitters are included that emit at different wavelengths of light than the UV emitter and the conversion material. The lamp emits a white light combination of light emitted from the complimentary emitters and from the conversion material, with the white light having high efficacy and good color rendering. Other embodiments of white light emitting lamp according to the present invention comprises a solid state laser instead of a UV emitter. A high flux white emitting lamp embodiment according to the invention comprises a large area light emitting diode (LED) that emits light at a first wavelength spectrum and includes a conversion material.

Abstract: One embodiment of the present invention is a seedling container having seedling compartment(s). Frangible tear-off strip(s) divide seedling compartment(s) into top portion(s) and bottom portion(s). Pulling on pull tab(s) of frangible strip(s) permits removal of frangible strip(s) from seedling compartment(s) so as to permit bottom portion(s) to be conveniently removed from top portion(s). Seedling plug(s) retained by rim-like top portion(s) may thus be conveniently transplanted without creating excessive mess or damage to seedling(s).

Abstract: A wound dressing applicator (10) for applying hydrocolloid dressings, compositions for tissue regeneration and the like to a patient's skin. Known wound dressing applicators do not effectively protect against contamination of the wound dressing and/or can be fiddly and difficult to operate and be rendered unusable by unwanted premature separation of the various layers of material adhered to one another. The present applicator comprises a rigid body (20) having a rigid body enclosure (30) for receiving a wound dressing, and an ejector (40) for ejecting the wound dressing from the rigid body enclosure and onto a patient's wound. This enables effective and aseptic handling of a wound dressing and application of the wound dressing onto a patient's wound.

Abstract: A method of underwater communication between a link initiator and a link receptor, by transmitting a link acquisition waveform from the initiator to the receptor, and establishing communications channel parameters from such a received waveform. Data is then transmitted according to these parameters, which may include range, direction, frequency band and Doppler, with greater efficiency and robustness.