Abstract: A disposable puncture device guide for use with an ultrasound probe is described. The puncture device guide includes a fixed portion configured to attach directly or indirectly to the probe body and a deflection portion connected to the fixed portion by at least one living hinge. The deflection portion comprises at least one groove configured support a puncture device therein. Outward pressure on the at least one groove causes the deflection portion to rotate outwardly relative to the fixed portion to support the puncture device throughout a range of angles.

Abstract: The present invention relates to a vaccine composition comprising an influenza Type A hemagglutinin stabilized stem nanoparticle (HA-ss-np); an aluminum hydroxide; a synthetic oligodeoxynucleotide adjuvant containing at least one CpG motif (CpG ODN); and a phosphate salt, wherein the HA-ss-np is not substantially adsorbed to the aluminum hydroxide, and wherein at least a portion of the CpG ODN is adsorbed to the aluminum hydroxide in the composition. The present disclosure also provides a method of inducing an immunological response against an influenza virus in a subject in need thereof, comprising administering an immunologically effective amount of the vaccine composition described herein.

Abstract: Described herein, are devices and methods that introduce polymeric additives in catalyst layer ink formulations that mitigate catalyst layer cracking and increase electrochemical performance in electrochemical fuel cells, including hydrogen fuel cells.

Abstract: An interchangeable mouthpiece for an inhalator, in particular for an electronic cigarette product, a conventional cigarette product or a medical inhaler, comprises a housing which forms an interior space and has an air inlet opening and an air outlet opening, an adapter by means of which the mouthpiece is connectable to a mouth-side end of the inhalator so that the air inlet opening is flow-coupled to the inhalator in a connected state, and a data acquisition device which at least comprises a sensor, a data memory, a processor and an energy storage unit, with a flow channel being formed in the interior of the housing as a result of a separation and flow-connecting the air inlet opening to the air outlet opening, and with the data acquisition device being configured to store, in the data memory, a data record comprising at least an operational parameter depending on a fluidic condition within the flow channel.

Abstract: According to embodiments, a substantially coaxial arrangement of a camera, a light source, and an ultrasonic sensor can be positioned in an housing of a system that can be deployed from the tool port of a standard bronchoscope. Illumination from the light source facilitates positioning of the system by an operator using information from the camera. The ultrasonic system can determine when an object to be biopsied is adjacent to a biopsy needle.

Abstract: A multi-stage process for the production of an ISO 8217 compliant Product Heavy Marine Fuel Oil from ISO 8217 compliant Feedstock Heavy Marine Fuel Oil involving a Reaction System composed of one or more reactor vessels selected from a group reactor wherein said one or more reactor vessels contains one or more reaction sections configured to promote the transformation of the Feedstock Heavy Marine Fuel Oil to the Product Heavy Marine Fuel Oil. The Product Heavy Marine Fuel Oil has a Environmental Contaminate level has a maximum sulfur content (ISO 14596 or ISO 8754) between the range of 0.05 mass % to 1.0 mass. A process plant for conducting the process for conducting the process is disclosed that can utilize a modular reactor vessel.

Abstract: A method of separating plastic material from battery materials can include: a) receiving battery materials in an immersion comminuting apparatus; b) by carrying out at least a first size reduction of the battery materials under immersion to create a primary-reduced metal material, primary-reduced plastic material and liberating a first amount of a black mass material; c) extracting at least a primary plastics slurry from the primary comminuting apparatus, wherein the primary plastics slurry comprises a mixture of the primary-reduced plastic material, a portion of the primary-reduced metal material and a portion of the black mass material liberated by the immersion comminuting apparatus; and d) carrying out a further, second size reduction of the plastic slurry using a non-immersion comminuting apparatus that is downstream from the immersion comminuting apparatus.

Abstract: A telescoping mast assembly with stop device. The telescoping mast assembly includes multiple pillars, one or more of which is able to be moved between an extended position and a retracted position. The stop device is mountable to the telescoping mast assembly and functions to prevent the rapid movement of the telescoping mast assembly from the extended position to the retracted position. The stop device includes a pin coupled to a pulley and is movable between an engaged position, in which the stop device restricts the movement a pillar, and a disengaged position in which the stop device does not restrict the movement of the pillar.

Abstract: Methods, devices and systems are disclosed for inter-app communications between software applications on a mobile communications device. In one aspect, a computer-readable medium on a mobile computing device comprising an inter-application communication data structure to facilitate transitioning and distributing data between software applications in a shared app group for an operating system of the mobile computing device includes a scheme field of the data structure providing a scheme id associated with a target software app to transition to from a source software app, wherein the scheme id is listed on a scheme list stored with the source software app; and a payload field of the data structure providing data and/or an identification where to access data in a shared file system accessible to the software applications in the shared app group, wherein the payload field is encrypted.

Abstract: The techniques herein are directed generally to a “zero-knowledge” data management network. Users are able to share verifiable proof of data and/or identity information, and businesses are able to request, consume, and act on the data-all without a data storage server or those businesses ever seeing or having access to the raw sensitive information (where server-stored data is viewable only by the intended recipients, which may even be selected after storage). In one embodiment, source data is encrypted with a source encryption key (e.g., source public key), with a rekeying key being an encrypting combination of a source decryption key (e.g., source private key) and a recipient's public key. Without being able to decrypt the data, the storage server can use the rekeying key to re-encrypt the source data with the recipient's public key, to then be decrypted only by the corresponding recipient using its private key, accordingly.

Abstract: A headrest storage pocket for use in a vehicle headrest seat is disclosed. The headrest storage pocket for use in a vehicle seat comprises a pocket made of a webbing, wherein that pocket is attached to a rear surface of the headrest of the vehicle seat. The headrest storage pocket also comprises an elastic band attached to a top edge of the pocket, wherein the pocket having a first side edge, a second side edge and a bottom edge. The first side edge, second side edge and bottom edge are secured to the rear surface of the headrest via at least one sewn seam. The headrest storage pocket may allow for storage of objects in the back rear surface of the vehicle headrest thus preventing the objects from being thrown around the interior compartment of the vehicle during driving thereof and keeping the objects in an easy to reach area of the vehicle.

Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter di of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.

Abstract: The disclosure provides at least one entity chosen from compounds of Formula I, a tautomer thereof, a deuterated derivative of that compound or tautomer, and a pharmaceutically acceptable salt of any of the foregoing, compositions comprising the same, and methods of using the same, including uses in treating APOL1-mediated diseases, including pancreatic cancer, focal segmental glomerulosclerosis (FSGS), and/or non-diabetic kidney disease (NDKD).

Abstract: Embodiments of negative pressure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, a system includes a pump assembly, canister, and a wound dressing configured to be positioned over a wound. The pump assembly, canister, and the wound dressing can be fluidically connected to facilitate delivery of negative pressure to a wound. The pump assembly can present graphical user interface screens for controlling and monitoring delivery of negative pressure. The system can be configured to efficiently deliver negative pressure and to detect and indicate presence of certain conditions, such as low pressure, high pressure, leak, canister full, and the like. Monitoring and detection of operating condition can be performed by measuring one or more operational parameters, such as pressure, flow rate, and the like.

Abstract: The present disclosure concerns a composition for an implantable pharmaceutical composition prepared from components consisting only of calcium sulfate ?-hemihydrate in combination with two antibiotics, vancomycin and gentamicin, for the treatment of infection in bone and soft tissue.

Abstract: A laser perforation system, including a drive roller, a tensioner roller spaced apart from the drive roller, a thin film belt arranged around both the drive roller and tensioner roller, the thin film belt including a front surface facing radially outward and a rear surface facing radially inward, a backstop arranged radially within the thin film belt, and a laser head arranged proximate the front surface, the laser head operatively arranged to direct a laser at the thin film belt to create holes therein.

Abstract: An apparatus and method for transferring a fluid sample from a fluid sample collection apparatus to a liquid sample analyzer. The apparatus includes a barrel having a first end, a second end, a sidewall extending between the first end and the second end, and an inner surface defining an internal chamber. The first end has an inlet opening and the second end having an outlet opening. The first end of the barrel has a barrel connection portion engageable with a portion of the fluid sample collection apparatus and the second end of the barrel has a tubular portion configured to engage with the liquid sample analyzer so a combination of the fluid sample collection apparatus and the barrel is attachable to the liquid sample analyzer with no additional support.

Abstract: A pipeline pig system is adapted to clean a pipe before applying a chemical to an interior wall of the pipe. The pipeline pig system includes a cleaning pig and an applicator pig. The applicator pig is configured to follow behind the cleaning pig as the cleaning pig and applicator pig move in a lateral direction through the pipe. Examples of chemicals include one or more of a corrosion inhibitor, a biocide, a paraffin inhibitor, an asphaltene inhibitor, a surface wetting agent, a cleaning compound, an iron chelator, a solvent, a dispersant, a surfactant, an internal film forming material, and a drag reducer.

Abstract: The present disclosure provides autonomous vehicle systems and methods that include or otherwise leverage a motion planning system that generates constraints as part of determining a motion plan for an autonomous vehicle (AV). In particular, a scenario generator within a motion planning system can generate constraints based on where objects of interest are predicted to be relative to an autonomous vehicle. A constraint solver can identify navigation decisions for each of the constraints that provide a consistent solution across all constraints. The solution provided by the constraint solver can be in the form of a trajectory path determined relative to constraint areas for all objects of interest. The trajectory path represents a set of navigation decisions such that a navigation decision relative to one constraint doesn't sacrifice an ability to satisfy a different navigation decision relative to one or more other constraints.