Abstract: Woven irrigation tubing comprising a woven, extrusion coated & laminated tube formed of a high density polyethylene (HDPE) outer layer, a low density polyethylene (LDPE) middle layer and a linear low density polyethylene (LLDPE) inner layer. The finished tubing is treated for ultraviolet resistance. The tubing is tied off at a distal end with a proximal end connected to a pressurized irrigation source. Watering holes are created in the tubing at spaced intervals and the resulting water streams are directed into parallel plowed furrows. The tubing is completely recyclable. The tubing is formed by manufacturing tape for the woven outer tubing cover, stretching the tape along its length to strengthen it, weaving the outer layer from the tape, flattening the woven outer layer, extrusion coating each surface of the outer layer with LDPE, laminating the LLDPE inner layer to the LDPE, reversing and winding the tubing for storage and distribution.

Abstract: This invention relates to methods and compositions for assessing or monitoring an amount of donor-specific fraction cell-free DNA from a transplant subject and comparing to specific threshold values for making treatment management decisions.

Abstract: This invention relates to methods and compositions for assessing an amount of total cell-free DNA, such as from a transplant subject. The methods and composition provided herein can be used to determine risk of complications following transplantation, including infection, cardiac arrest, and death, in a subject.

Abstract: A smart-home device may include a temperature sensor, energy-consuming subsystems, and processors programmed to receive a temperature measurement from the temperature sensor for an ambient environment surrounding the temperature sensor; receive inputs from the energy-consuming subsystems that indicate power-consuming activities of the energy-consuming subsystems; providing the inputs from the energy-consuming subsystems to a model that is trained to calculate an effect of the power-consuming activity of the energy-consuming subsystems on the temperature measurement from the temperature sensor; and calculating an estimate of the temperature of the ambient environment by compensating the temperature measurement from the temperature sensor with using the effect of the power-consuming activity of the energy-consuming subsystems.

Abstract: Provided herein are compositions comprising a lipid nanoparticle (LNP) formulation comprising a LNP having encapsulated therein a barcoded mRNA (b-mRNA), and methods for using the same. Such methods include analyzing in vivo delivery of a composition.

Abstract: Systems and methods for monitoring mobile devices in a controlled environment are provided. One or more mobile devices may be accessible through a communication port of the mobile device. One or more monitoring devices may be configured to monitor the one or more mobile devices. A processor in communication with the one or more monitoring devices may control the monitoring devices and receive signals from the monitoring devices. A server in communication with the mobile devices may create a communication channel with each of the mobile devices, with each communication channel accessible through a network for use by software developers and testers. Thus, monitoring and detection of malfunctions or other abnormalities of the mobile devices is achieved, and remediation may be performed.

Abstract: Modulating and optimizing operation parameters such as power usage of wireless networks include determining a baseline reference level for a network demand at a base station in a network during a first time interval. The transmission power of the base station corresponding to the baseline reference level is determined, and the network demand at the base station in the network is forecasted during a second time interval. A difference between the projected network demand and the baseline reference level at the second time is determined. The transmission power of the base station is adjusted by a predetermined increment during the second time interval based at least on the difference.

Abstract: Woven irrigation tubing comprises a woven, extrusion coated & laminated tube formed of a high density polyethylene (HDPE) outer layer, a low density polyethylene (LDPE) middle layer and a linear low density polyethylene (LLDPE) inner layer. The finished tubing is treated for ultraviolet resistance. The tubing is tied off at a distal end with a proximal end connected to a pressurized irrigation source. Watering holes are created in the tubing at spaced intervals and the resulting water streams are directed into parallel plowed furrows. The tubing is completely recyclable. The tubing is formed by manufacturing tape for the woven outer tubing cover, stretching the tape along its length to strengthen it, weaving the outer layer from the tape, flattening the woven outer layer, extrusion coating each surface of the outer layer with LDPE, laminating the LLDPE inner layer to the LDPE, reversing and winding the tubing for storage and distribution.

Abstract: Systems and methods are provided for using automated mobile computing device testing to ensure that a given targeted message is actually appearing in an intended manner for various types of intended recipients. The intended content or format of a target message to be presented by each of a plurality of mobile computing devices may be based on characteristics of each device. The targeted message may be sent to each device, and an indication of the actual content and/or format of the targeted message as presented by each device may be received and compared to the intended content or format of the targeted message for each device. Errors associated with the targeted message may be detected based on any discrepancies between the intended content and/or format of the targeted message for each device and the actual content or format of the targeted message as presented by each device.

Abstract: This invention relates to methods and compositions for assessing an amount of total cell-free DNA, such as from a transplant subject. The methods and composition provided herein can be used to determine risk of complications following transplantation, including infection, cardiac arrest, and death, in a subject.

Abstract: A smart-home device may include an energy-storage element that stores energy harvested from an environmental system; a power wire connector and a return wire connector; and switching elements configured to operate in a first state where the switching elements create a connection between the power and the return; and a second state where the switching elements interrupt the connection between the power and return. The smart-home device may also include a circuit that controls the switching elements, where the circuit is configured to detect a zero-crossing of a current received through the power wire connector; wait for a first time interval after the zero-crossing is detected; after an expiration of the first time interval, enable active power stealing for a second time interval; and after an expiration of the second time interval, disable active power stealing.

Abstract: This invention relates to methods and compositions for assessing an amount of total cell-free DNA, such as from a subject having a pro-inflammatory response, such as a pro-inflammatory response associated with an infection, such as a COVID-19 infection. This invention also relates to compositions and methods for treating subjects having or suspected of having a pro-inflammatory response, such as a pro-inflammatory response associated with an infection, such as a COVID-19 infection. In embodiments, there is a risk of an inappropriate or detrimental pro-inflammatory response, such as in a subject with a COVID-19 infection. The methods and composition provided herein can be used to determine severity and risk of complications in a subject. The methods and composition provided herein can also be used to assess the effectiveness of a therapy in a subject, such as a COVID-19 subject.

Abstract: A method of powering a controller using an intermediate device with power from an environmental system may include receiving current from a power wire from the environmental system; passing the current from the power wire to a second command wire from the controller; monitoring the current flowing between the power wire and the second command wire while the current is below a threshold indicative of an amount of current used to power the controller from the environmental system; detecting when the current flowing between the power wire and the second command wire exceeds the threshold indicating that the controller is sending a command to the environmental system to perform the function; and sending a command to environmental system using a first command wire from the environmental system after detecting that the current exceeds the threshold.

Abstract: Systems and methods are provided for using automated mobile computing device testing to ensure that a given targeted message is actually appearing in an intended manner for various types of intended recipients. The intended content or format of a target message to be presented by each of a plurality of mobile computing devices may be based on characteristics of each device. The targeted message may be sent to each device, and an indication of the actual content and/or format of the targeted message as presented by each device may be received and compared to the intended content or format of the targeted message for each device. Errors associated with the targeted message may be detected based on any discrepancies between the intended content and/or format of the targeted message for each device and the actual content or format of the targeted message as presented by each device.

Abstract: Systems and methods relating to detection and remediation of underperforming third party processes are disclosed. Such systems and methods include implementing web page performance profiling by loading a target web page in a selected testing environment and acquiring data related to performance metrics of third party processes in the selected testing environment. The techniques may be applied to manage third party embedded processes on a client website and implementing a corrective action to remediate the impacting events before the underperforming third party processes are further accessed, thus improving website performance.

Abstract: A smart-home device may include a plurality of wire connectors configured to receive a plurality of signals from an environmental system; a plurality of diodes configured to receive the plurality of signals from the plurality of wire connectors, wherein at least two of the plurality of diodes have different voltage drops; and a power-stealing circuit that is configured to receive outputs of the plurality of diodes and to steal power through one of the plurality of wire connectors that is determined at least in part by the different voltage drops.

Abstract: A method of powering a controller using an intermediate device with power from an environmental system may include receiving current from a power wire from the environmental system; passing the current from the power wire to a second command wire from the controller; monitoring the current flowing between the power wire and the second command wire while the current is below a threshold indicative of an amount of current used to power the controller from the environmental system; detecting when the current flowing between the power wire and the second command wire exceeds the threshold indicating that the controller is sending a command to the environmental system to perform the function; and sending a command to environmental system using a first command wire from the environmental system after detecting that the current exceeds the threshold.

Abstract: The present invention relates to lipids and compositions thereof. In various aspects of the invention, the compositions are lipid nanoparticle compositions used to deliver various nucleic acid molecules and/or therapeutic agents to selected targets, such as cells for gene delivery, and/or to prevent or treat diseases or disorders in a subject in need thereof.

Abstract: The present invention relates to lipid nanoparticles (LNP) or compositions thereof for delivery of mRNA molecules encoding CAR, nucleic acid molecule, and/or therapeutic agents to selected targets, such as cells. Thus, in various aspects, the present invention also provides methods of preventing or treating diseases or disorders in a subject in need thereof using the said LNPs or compositions thereof.

Abstract: Methods and systems are disclosed for coordinating content selection across devices. A user device may transmit a request for webpage content and in response, may receive response communications that include the webpage content, embedded content, and a script. The user device may retrieve a device identifier initially generated by a remote system from a locally stored data object. The user device can detect, using the script, whether at least part of the embedded content is being presented within a portion of the webpage that is displayed on a screen of the user device. The user device may then transmit a report communication to a remote ID-graph system that includes the device identifier and an indication as to whether the at least part of the embedded content was presented within the portion of the webpage that was displayed on the screen of the user device.