Patents by Inventor Michael A. North
Michael A. North has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140239093Abstract: A traveling sprinkler system comprising: a sphere shaped surface; at least one wheel over a circumference of the sphere shaped surface, where the at least one wheel divides the sphere into a first half and a second half; a plurality of holes on both the first half and the second half of the sphere shaped surface; a water hose receptacle, where the water hose receptacle receives a flow of water from a water hose; and wheel gears within the sphere, where the flow of water transfers over the wheel gears to enable the movement of the at least one wheel and the flow of water transfers through the plurality of holes creating a sprinkling action.Type: ApplicationFiled: February 22, 2013Publication date: August 28, 2014Inventors: Michael North, Dehlia Dodd
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Patent number: 8399647Abstract: The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin ?5?1 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies or antigen binding portions thereof are also provided. The disclosure also provides methods for treating various cancers using the anti-?5?1 antibodies or antigen binding portions thereof described herein.Type: GrantFiled: September 20, 2011Date of Patent: March 19, 2013Assignees: Pfizer Inc., Bristol-Myers Squibb CompanyInventors: Steven L. Bender, Gerald F. Casperson, Dana D. Hu-Lowe, Xin Jiang, Gang Li, Michael A. North, Jianying Wang, Grant Wickman, Peter Brams, Haichun Huang, Brigitte Devaux, Haibin Chen, Dawn M. Tanamachi, Kristopher Toy, Lan Yang, Tim W. Sproul, Mark Yamanaka
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Patent number: 8345258Abstract: An optical device for characterizing a test surface combines a Fizeau interferometer with a polarization frequency-shifting element. Two substantially collinear, orthogonally polarized beams having respective frequencies differing by a predetermined frequency shift are generated by the polarization frequency-shifting element and projected into the Fizeau optical cavity to produce a pair of test beams and a pair of reference beams, wherein the beams in each pair have orthogonal polarization states and have frequencies differing by the predetermined frequency shift. A second, substantially equal frequency shift is introduced in the Fizeau cavity on either one of the pairs of test and reference beams, thereby generating a four-beam collinear output that produces an interferogram without tilt or short-coherence light. The invention may also be implemented by reversing the order of the Fizeau cavity and the polarization frequency-shifting element in the optical train.Type: GrantFiled: February 6, 2010Date of Patent: January 1, 2013Assignee: 4 D Technology CorporationInventors: James E. Millerd, Michael North-Morris
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Publication number: 20120009622Abstract: The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin ?5?1 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies or antigen binding portions thereof are also provided. The disclosure also provides methods for treating various cancers using the anti-?5?1 antibodies or antigen binding portions thereof described herein.Type: ApplicationFiled: September 20, 2011Publication date: January 12, 2012Inventors: Steven L. Bender, Gerald F. Casperson, Dana D. Hu-Lowe, Xin Jiang, Gang Li, Michael A. North, Jianying Wang, Grant Wickman, Peter Brams, Haichun Huang, Brigitte Devaux, Haibin Chen, Dawn M. Tanamachi, Kristopher Toy, Lan Yang, Tim W. Sproul, Mark Yamanaka
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Publication number: 20110319634Abstract: Dimeric aluminium catalysts of formula I: and their use in catalysing the synthesis of cyclic carbonates from epoxides and carbon dioxide.Type: ApplicationFiled: March 17, 2010Publication date: December 29, 2011Applicant: UNIVERSITY OF NEWCASTLE UPON TYNEInventor: Michael North
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Publication number: 20110165170Abstract: The present disclosure provides isolated antibodies, particularly human antibodies, or antigen binding portions thereof, that bind to osteopontin with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies or antigen binding portions thereof are also provided. The disclosure also provides methods for treating various cancers using the anti-osteopontin antibodies or antigen binding portions thereof described herein.Type: ApplicationFiled: August 19, 2010Publication date: July 7, 2011Applicant: Pfizer Inc.Inventors: Trisha Ann Haubrich, Justin Thomas Bingham, Jitesh Pranial Jani, Alessandra Blasina, Kathrin Ladetzki-Baehs, Michael Tesar, Justin Guy Chapman, Dirk Ponsel, Michael A. North
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Publication number: 20110015409Abstract: A dimeric aluminium(salen) catalyst of formula I: wherein: Y-Q is CRC1?N or CRC1RC2—NRN1, where RC1, RC2 and RN1 are independently selected from H, halo, optionally substituted C1-20 alkyl, optionally substituted C5-20 aryl, ether and nitro; each of the substituents R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, and R16, is independently selected from H, halo, optionally substituted C1-20 alkyl, optionally substituted C5-20 aryl, optionally substituted C3-20 heterocyclyl, ether and nitro; X1 and X2 are independently either (i) a C2-5 alkylene chain, which is optionally substituted by one or more groups selected from C1-4 alkyl and C5-7 aryl, or a C1-3 bisoxyalkylene chain, which is optionally substituted by one or more groups selected from C1-4 alkyl and C5-7 aryl or (ii) represent a divalent group selected from C5-7 arylene, C5-7 cyclic alkylene and C3-7 heterocyclylene, which may be optionally substituted; (i) (a) at least one of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13,Type: ApplicationFiled: March 6, 2009Publication date: January 20, 2011Applicant: UNIVERSITY OF NEWCASTLE UPON TYNEInventor: Michael North
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Publication number: 20100330078Abstract: The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin ?5?1 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies or antigen binding portions thereof are also provided. The disclosure also provides methods for treating various cancers using the anti-?5?1 antibodies or antigen binding portions thereof described herein.Type: ApplicationFiled: February 4, 2009Publication date: December 30, 2010Inventors: STEVEN L. BENDER, GERALD F. CASPERSON, DANA D. HU-LOWE, XIN JIANG, GANG LI, MICHAEL A. NORTH, JIANYING WANG, GRANT WICKMAN, PETER BRAMS, HAICHUN HUANG, BRIGITTE DEVAUX, HAIBIN CHEN, DAWN M. TANAMACHI, KRISTOPHER TOY, LAN YANG, TIM W. SPROUL, MARK YAMANAKA
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Publication number: 20100134801Abstract: An optical device for characterizing a test surface combines a Fizeau interferometer with a polarization frequency-shifting element. Two substantially collinear, orthogonally polarized beams having respective frequencies differing by a predetermined frequency shift are generated by the polarization frequency-shifting element and projected into the Fizeau optical cavity to produce a pair of test beams and a pair of reference beams, wherein the beams in each pair have orthogonal polarization states and have frequencies differing by the predetermined frequency shift. A second, substantially equal frequency shift is introduced in the Fizeau cavity on either one of the pairs of test and reference beams, thereby generating a four-beam collinear output that produces an interferogram without tilt or short-coherence light. The invention may also be implemented by reversing the order of the Fizeau cavity and the polarization frequency-shifting element in the optical train.Type: ApplicationFiled: February 6, 2010Publication date: June 3, 2010Applicant: 4D TECHNOLOGY CORPORATIONInventors: JAMES E. MILLERD, MICHAEL NORTH-MORRIS
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Publication number: 20100130752Abstract: A process for the production of cyclic carbonates comprising contacting an epoxide with carbon dioxide in the presence of a dimeric aluminium(salen) catalyst, and a co-catalyst capable of supplying Y?, where Y is selected from Cl, Br and I, where the dimeric aluminium(salen) catalyst is of formula I:Type: ApplicationFiled: April 25, 2008Publication date: May 27, 2010Applicant: UNIVERSITY OF NEWCASTLE UPON TYNEInventor: Michael North
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Patent number: 7675628Abstract: An optical device for characterizing a test surface combines a Fizeau interferometer with a polarization frequency-shifting element. Two substantially collinear, orthogonally polarized beams having respective frequencies differing by a predetermined frequency shift are generated by the polarization frequency-shifting element and projected into the Fizeau optical cavity to produce a pair of test beams and a pair of reference beams, wherein the beams in each pair have orthogonal polarization states and have frequencies differing by the predetermined frequency shift. A second, substantially equal frequency shift is introduced in the Fizeau cavity on either one of the pairs of test and reference beams, thereby generating a four-beam collinear output that produces an interferogram without tilt or short-coherence light. The invention may also be implemented by reversing the order of the Fizeau cavity and the polarization frequency-shifting element in the optical train.Type: GrantFiled: September 7, 2007Date of Patent: March 9, 2010Assignee: 4D Technology CorporationInventors: James E. Millerd, Michael North-Morris
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Patent number: 7524082Abstract: A cable includes a waveguide with a lighting system removeably attached to it. The lighting system includes a plurality of light emitters extending along the waveguide and connected together with conductive lines. The lighting system also includes light emitter connectors which can be engaged with a power source to activate the light emitters. The activation of the light emitters is useful in cable tracing because it indicates where the waveguide extends.Type: GrantFiled: February 16, 2007Date of Patent: April 28, 2009Inventor: Todd Michael North
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Publication number: 20080198618Abstract: A cable includes a waveguide with a lighting system removeably attached to it. The lighting system includes a plurality of light emitters extending along the waveguide and connected together with conductive lines. The lighting system also includes light emitter connectors which can be engaged with a power source to activate the light emitters. The activation of the light emitters is useful in cable tracing because it indicates where the waveguide extends.Type: ApplicationFiled: February 16, 2007Publication date: August 21, 2008Inventor: Todd Michael North
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Publication number: 20080086364Abstract: An agent-based computer model having consumer agents, retailer agents, and manufacturer agents represents the major participants in consumer packaged goods markets.Type: ApplicationFiled: October 5, 2007Publication date: April 10, 2008Inventors: June Hahn, Michael North
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Publication number: 20080062428Abstract: An optical device for characterizing a test surface combines a Fizeau interferometer with a polarization frequency-shifting element. Two substantially collinear, orthogonally polarized beams having respective frequencies differing by a predetermined frequency shift are generated by the polarization frequency-shifting element and projected into the Fizeau optical cavity to produce a pair of test beams and a pair of reference beams, wherein the beams in each pair have orthogonal polarization states and have frequencies differing by the predetermined frequency shift. A second, substantially equal frequency shift is introduced in the Fizeau cavity on either one of the pairs of test and reference beams, thereby generating a four-beam collinear output that produces an interferogram without tilt or short-coherence light. The invention may also be implemented by reversing the order of the Fizeau cavity and the polarization frequency-shifting element in the optical train.Type: ApplicationFiled: September 7, 2007Publication date: March 13, 2008Applicant: 4D TECHNOLOGY CORPORATIONInventors: James E. Millerd, Michael North-Morris
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Publication number: 20080031761Abstract: A rotor for a screw vacuum pump has a threaded body in which a central cavity is formed. A coolant is supplied to the cavity from a supply line provided in a shaft attached to the body. A coolant flow guide, which may be either separate from or at least partially integral with the shaft, is located within the cavity. The flow guide has an outer surface adjacent, preferably in contact with, the body to enable heat to be transferred from the rotor to the guide. The guide also has an inner surface defining a bore, and defines at least in part a plurality of axially extending channels radially spaced from and in fluid communication with the bore. In use, coolant flows into the cavity through the bore of the guide, and out from the cavity through the axially extending channels, extracting heat from the guide as it flows both into and out from the cavity. The discharged coolant is conveyed from the channels into a discharge line located within the shaft.Type: ApplicationFiled: August 17, 2005Publication date: February 7, 2008Inventor: Michael North
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Patent number: 7326312Abstract: The process for laying a non-full width course of fiber composite tape in a part is designed to ensure that all of the scrap portion of the tape surrounding the non-full width course is deposited in the scrap area and not in the part. An extra cut is made in tape downstream of the non-full width course, between the non-full width course and next course. After the tape head attempts to lay the scrap in the scrap area in the forward direction, the tape head makes a pass in the scrap area with the tape feed and the tape head moving in the reverse direction, and the scrap is laid beginning from the portion of the tape having the extra cut, and progressing to the non-full width course. The method may be used to remove scrap from around non-full width courses having any shape.Type: GrantFiled: September 9, 2004Date of Patent: February 5, 2008Assignee: MAGUS Intellectual Property GmbHInventors: Ralph John Rust, Michael North Grimshaw, James Richard Hecht
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Patent number: 7314844Abstract: A process for cyanating an aldehyde is provided. The process comprises reacting the aldehyde with: i) a cyanide source which does not comprise a Si—CN bond or a C—(C?O)—CN moiety; and ii) a substrate susceptible to nucleophilic attack not comprising a halogen leaving group; in the presence of a chiral catalyst. Preferably, the chiral catalyst is a chiral vanadium or titanium catalyst. The cyanide source is preferably an alkali metal cyanide and the substrate susceptible to nucleophilic attack not comprising a halogen leaving group is a carboxylic anhydride.Type: GrantFiled: April 26, 2005Date of Patent: January 1, 2008Assignees: King's College London, Nesmeyanov Institute of Organoelement CompoundsInventors: Michael North, Yuri Belokon
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Publication number: 20070065444Abstract: The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to the extracellular domain (ECD) of activin receptor-like kinase-1 (ALK-1) and that function to abrogate the ALK-1/TGF-beta-1/Smad1 signaling pathway. The invention also relates to heavy and light chain immunoglobulins derived from human anti-ALK-1 antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human anti-ALK-1 antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.Type: ApplicationFiled: September 6, 2006Publication date: March 22, 2007Applicants: Amgen Fremont Inc., Pfizer Inc.Inventors: Michael North, Karin Amundson, Vahe Bedian, Shelley Belouski, Dana Hu-Lowe, Xin Jiang, Shannon Karlicek, Sirid Kellermann, James Thomson, Jianying Wang, Grant Wickman, Jingchuan Zhang
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Patent number: 7121269Abstract: The present invention discloses an air-entrainment mechanism for carbureted engine. The mechanism includes a plunger valve controlled by a solenoid. The solenoid is powered by a battery with a switch electrically coupled thereto. The plunger valve is interconnected to the carburetor to allow additional air entrainment. The solenoid is coupled to the valve for opening and closing the valve. The switch electrically couples the solenoid to the battery to activate the solenoid for movement of the valve. The switch disclosed herein includes a temperature sensor and an engine-running sensor. The switch is then closeable when the temperature sensor detects an engine temperature within a predetermined range as long as the engine is not already running.Type: GrantFiled: April 16, 2004Date of Patent: October 17, 2006Inventor: Michael North