Abstract: A method for an online mapping system includes localizing a location of an ego vehicle relative to an offline feature map. The method also includes querying surrounding features of the ego vehicle based on the offline feature map. The method further includes generating a probabilistic map regarding the surrounding features of the ego vehicle queried from the offline feature map.

Abstract: The present invention includes a method for the use of N-acetylcysteine (NAC), N-acetylcysteine amide (NAC A) or (2R,2R?)-3,3?-disulfanediylbis(2-acetamidopropanamide) (diNACA) for the prevention and treatment of radiation dermatitis, radiation damage to the skin, xeroderma pigmentosa or protect patients with xeroderma pigmentosa from skin damage caused by exposure to the sun or other radiation, bioweapons, chemical burns, heat burns, contact damage caused by friction, contact dermatitis, hypersensitivity reactions and skin wrinkles and dehydration, skin lightening, skin whitening, and/or skin improvement in a human that comprises administering to the human a therapeutically effective amount of NAC, NACA or diNACA.

Abstract: A cover sheet (7) for a photovoltaic panel (4), the cover sheet (7) comprising a transparent substrate (8) and a coating (9) on the substrate (8), the coating (9) being such that the cover sheet (8) is more reflective to light of a first range of wavelengths in the infrared spectrum than to a second range of wavelengths in the visible spectrum; in which the coating (9) comprises alternating layers of first (11, 13) and second (12, 14) materials, with the first material (11, 13) having a higher refractive index than the second material (12, 14) and being a transparent conducting oxide such as indium tin oxide (ITO). Methods of manufacture including annealing the first material and/or depositing it at elevated temperatures are also discussed.

Abstract: The present invention includes a method for the use of N-acetylcysteine amide (NACA) or (2R,2R?)-3,3?-disulfanediyl bis(2-acetamidopropanamide) (diNACA) for prevention and treatment of radiation pneumonitis and treatment of pulmonary function in Cystic Fibrosis (CF), chronic obstructive pulmonary disease (COPD), or bronchitis in a human that comprises administering to the human a therapeutically effective amount of NACA or diNACA sufficient to treat, reduce the symptoms, or prevent radiation pneumonitis and treatment of pulmonary function in Cystic Fibrosis (CF), chronic obstructive pulmonary disease (COPD), bronchitis, or respiratory disorder due to oxidative stress, and diNACA for the reduction of mucus viscosity and/or elasticity.

Abstract: The present invention includes methods for making and isolating N-acetylcysteine amide, (2R,2R?)-3,3?-disulfanediyl bis(2-acetamidopropanamide, diNACA), intermediates and derivatives thereof comprising: contacting cystine with an alcohol and a chlorinating reagent to form an organic solution containing L-cystine dimethylester dihydrochloride; combining dried or undried L-cystine dimethylester dihydrochloride with a triethylamine, an acetic anhydride, and an acetonitrile to form a di-N-acetylcystine dimethylester; mixing dried di-N-acetylcystine dimethylester with ammonium hydroxide to form a di-N-acetylcystine amide (diNACA); and separating dried di-N-acetylcystine dimethylester into N-acetylcysteine amide with dithiothreitol, triethylamine and an alcohol.

Abstract: A headgear for a respiratory mask has first and second straps configured to be connected to each other by first and second buckles. The straps are configured to overlap in a region that contacts the rear of a user's head. The overlapping regions of the first and second straps can be positioned in a bifurcated configuration to improve stability on a user's head. The first and second buckles can feature a glider end through which one of the first and second straps can slide and a strap attachment end to which the other strap is permanently connected. In some embodiments, the first and second buckles have two components that are pivotally connected to allow adjustment of the headgear size whilst in a bifurcated configuration.

Abstract: A mask frame, comprises a central conduit connection aperture and lateral arms having a 3-D curvature. The lateral arms extend: outwardly from a center of the frame, rearwardly, towards the patients ears, and upwardly, along a vector passing from below the nose to a point between the temple the top of the ear. The lateral arms “twist” along their length, such that a bottom margin of an end of each lateral arm is positioned further away from a notional vertical plane passing through the centre of the conduit connection aperture than a top margin. Also provided is an anti-rotation feature which limits or prevents rotation between straps of a headgear, and the mask frame. Further provided is a buckle for a closed loop headgear the buckle being formed with a plurality of openings and posts configured to form an angled headgear strap path through the buckle through which part of a headgear strap loop can pass.

Abstract: The present invention relates in general to the field of compositions and methods for using N-acetylcysteine amide (NACA) or (2R,2R?)-3,3?-disulfanediyl bis(2-acetamidopropanamide) (diNACA) for treating cystinosis. This present invention also relates to the general field of using NAC, NACA or diNACA to treat ophthalmic, ocular or corneal effects of cystinosis. This present invention also relates to the general field of using NAC, NACA, diNACA, cysteamine (or cysteamine salts, e.g., the hydrochloride salt or other salts) or any other cystine-depleting agent for treating ophthalmic, ocular or corneal effects of cystinosis by administration in an ophthalmic or ocular insert.

Abstract: The disclosure relates to a method for operating a system that includes at least one suction device and at least one hand-held power tool. The method includes establishing a communications link between the suction device and the hand-held power tool by means of at least one suction device communication unit and at least one hand-held power tool communication unit, and transmitting at least one communication signal by means of the communications link from the hand-held power tool, in particular the hand-held power tool communication unit, to the suction device, in particular the suction device communication unit. When the suction device is switched on, at least one start signal is sent to the hand-held power tool, the hand-held power tool being activatable only if the start signal is received by the hand-held power tool.

Abstract: Systems and methods for localization of a subject vehicle may include: a plurality of sensors to gather data regarding features in an environment of the subject vehicle; a feature map module to generate a feature map using data gathered from one or more of the plurality of sensors; a feature raster module to generate a feature raster image from the feature map; a score computation module to register a plurality of transformations of the feature raster image with a map feature raster image, to generate a cost function for the registrations of the plurality of transformations, and to determine the transformation with the lowest cost function; and the score computation module using the transformation with the lowest cost function to determine localization of the subject vehicle.

Abstract: A respiratory mask system comprising a mask interface comprising a frame for a headgear assembly. The frame comprises a body comprising a first surface and a substantially opposing second surface. The body further comprises a gas inlet and optionally an outlet vent. The gas inlet may be substantially elliptical in shape. The frame may comprise a recessed region for receiving a yoke of a headgear assembly to attach the headgear to the mask interface. The respiratory mask system may also comprise a yoke for attaching to the frame.

Abstract: A headgear for a respiratory mask has first and second straps configured to be connected to each other by first and second buckles. The straps are configured to overlap in a region that contacts the rear of a user's head. The overlapping regions of the first and second straps can be positioned in a bifurcated configuration to improve stability on a user's head. The first and second buckles can feature a glider end through which one of the first and second straps can slide and a strap attachment end to which the other strap is permanently connected. In some embodiments, the first and second buckles have two components that are pivotally connected to allow adjustment of the headgear size whilst in a bifurcated configuration.

Abstract: A mask assembly including a mask frame with a central conduit connection aperture and lateral arms having a 3-D curvature. The lateral arms extend: outwardly from a center of the frame, rearwardly, towards the patients ears, and upwardly, along a vector passing from below the nose to a point between the temple the top of the ear. The mask assembly can include an anti-rotation feature which limits or prevents rotation between straps of a headgear, and the mask frame. The mask assembly can include a buckle for a closed loop headgear, the buckle being formed with a plurality of openings and posts configured to form an angled headgear strap path through the buckle through which part of a headgear strap loop can pass.

Abstract: The present invention includes methods for making and isolating N-acetylcysteine amide, (2R,2R?)-3,3?-disulfanediyl bis(2-acetamidopropanamide, diNACA), intermediates and derivatives thereof comprising: contacting cystine with an alcohol and a chlorinating reagent to form an organic solution containing L-cystine dimethylester dihydrochloride; combining dried or undried L-cystine dimethylester dihydrochloride with a triethylamine, an acetic anhydride, and an acetonitrile to form a di-N-acetylcystine dimethylester; mixing dried di-N-acetylcystine dimethylester with ammonium hydroxide to form a di-N-acetylcystine amide (diNACA); and separating dried di-N-acetylcystine dimethylester into N-acetylcysteine amide with dithiothreitol, triethylamine and an alcohol.

Abstract: A respiratory mask system comprising a mask interface comprising a frame for a headgear assembly. The frame comprises a body comprising a first surface and a substantially opposing second surface. The body further comprises a gas inlet and optionally an outlet vent. The gas inlet may be substantially elliptical in shape. The frame may comprise a recessed region for receiving a yoke of a headgear assembly to attach the headgear to the mask interface. The respiratory mask system may also comprise a yoke for attaching to the frame.

Abstract: The present invention includes a method for using diNACA as a prodrug to deliver diNACA, NACA and NAC to a mammal for therapeutic purposes to prevent or treat diseases or disorders involving oxidative stress. The method includes any disease that involves the therapeutic use of NACA or NAC as a therapeutic agent. Also, compositions and methods for the prevention, reduction or treatment of corneal endothelial cell loss in a patient that comprise providing the patient with an amount of at least one, alone or in combination, of N-acetylcysteine amide (NACA) or (2R,2R?)-3,3?-disulfanediyl bis(2-acetamidopropanamide) (diNACA) (diNACA) to prevent or reduce the corneal endothelial cell loss or to prevent or treat presbyopia. DiNACA can be used to prevent or treat cataracts.

Abstract: A headgear assembly can include a pair of opposing, semi-rigid side arms. Each side arm can be pivotally coupled to an interface at a single location. Each side arm can extend from the single location across the user's cheeks and above the user's ears in use. The headgear assembly can include a top strap coupled to the pair of opposing, semi-rigid side arms, the top strap configured to extend around the top of a user's head. The headgear assembly can include a rear strap coupled to the pair of opposing, semi-rigid side arms, the rear strap configured to extend around the rear of a user's head. The headgear assembly can include a chin strap coupled to the pair of opposing, semi-rigid side arms, the chin strap configured to extend around the user's chin.

Abstract: The disclosure relates to a circular saw, in particular a hand-held circular saw, having a housing and a drive unit, at least some sections of which are arranged in the housing and with which a tool holder for an exchangeable saw blade is associated. The drive unit is designed to rotationally drive the exchangeable saw blade about an associated axis of rotation. In the circular saw, a blade guard is associated with the exchangeable saw blade. The blade guard is mounted in the housing for rotation about the associated axis of rotation and extends around a cutting point of the exchangeable saw blade at least during a sawing operation in such a way that contact with the cutting point can be at least substantially prevented.

Abstract: A headgear system and/or an interface assembly incorporating a headgear system that, in some configurations, is configured to transform from elasticated or “stretchy” behavior to “inelastic” behavior at least in response to normal or expected forces encountered during the intended therapy. In some configurations, upon fitment to the head of a user, the system automatically adjusts toward or to an appropriate size. A headgear portion or assembly for use in combination with a breathing apparatus in some configurations is at least substantially inelastic and is three dimensional in shape. The headgear portion or assembly can comprise a plastic core and a textile casing. The headgear, or part thereof, may also have integrally moulded labels, connectors, adjustment mechanisms and/or grips.

Abstract: A headgear portion or assembly for use in combination with a breathing apparatus in some configurations is at least substantially inelastic and is three dimensional in shape. The headgear portion or assembly can comprise a plastic core and a textile casing. The headgear, or part thereof, may also have integrally moulded labels, connectors, adjustment mechanisms and/or grips.