Abstract: The present invention relates to a method for synthesizing templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.

Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.

Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

Abstract: A segregated area for the storage of regulated goods is subleased or otherwise acquired from the operator of a warehouse that is used to store unregulated goods. The segregated area can be manned with support personnel, and appropriately isolated or otherwise separated from the remainder of the host warehouse in accordance with applicable regulations. Upon receipt of a purchase order, regulated goods are transported, ideally along with unregulated goods, to a third party purchaser. Legal custody and control of such regulated goods is not transferred until such regulated goods are actually delivered to the ultimate purchaser.

Abstract: An A-pillar for a motor vehicle running from a vehicle roof in the direction of a vehicle floor and having a curved profile over at least one longitudinal section, has an essentially solid circumferential surface and is of essentially hollow configuration in an inner region. The A-pillar in its curved longitudinal section has a reinforcement strut which passes through a hollow cross section of the A-pillar. The reinforcement strut runs from a rear wall region of the A-pillar to a front wall region. The reinforcement strut may have an elliptical or a circular recess along an upper and a lower boundary line. The A-pillar thus achieves high strength at reduced weight.

Abstract: The invention relates to a tunnel bridge (1) of a motor vehicle with a support structure (4) featuring at least two side parts (2, 3) and ribs (5) at least at the side parts (2, 3) in which the tunnel bridge (1) is adapted to be connected to the body and/or beams (6, 7) of the motor vehicle. For the known tunnel bridges this would be detrimental. A significant improvement is achieved by a tunnel bridge (1) which is constituted as one piece made from a cast material together with the associated side parts (2, 3) and/or the connecting parts for the connection to the body and that the ribs (5) are located at the side parts (2, 3) and/or on a tunnel bridge part (8) which connects the side parts (2, 3).

Abstract: A slidable and hinged door, e.g., in a motor vehicle, in which the door is displaceable from the plane of a door opening by at least one swivel arm developed as a double hinge, and, for the sliding function, is displaceable into a plane arranged in front of it that is approximately parallel to it and is slidable in the plane arranged in front of it by a parallel guidance, may be simple to handle and to be operated by motor, at the same time as having a simple arrangement from a construction point of view. The swiveling motions and/or the swiveling possibilities for the operation of the door are able to be activated or determined within the double hinge by servomotors engaging at the first and the second hinge of the double hinge.

Abstract: A slidable and hinged door, e.g., in a motor vehicle, in which the door is displaceable from the plane of a door opening by at least one swivel arm developed as a double hinge, and, for the sliding function, is displaceable into a plane arranged in front of it that is approximately parallel to it and is slidable in the plane arranged in front of it by a parallel guidance, may be simple to handle and to be operated by motor, at the same time as having a simple arrangement from a construction point of view. The swiveling motions and/or the swiveling possibilities for the operation of the door are able to be activated or determined within the double hinge by servomotors engaging at the first and the second hinge of the double hinge.

Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.

Abstract: Nucleoside derivatives as building blocks for templated libraries are described.

Abstract: Specific peptide nucleic acid (PNA) probes for detecting a sexual transmitted disease caused by Neisseria gonorrhoeae or Chlamydia trachomatis comprising N-(2-aminoethyl)glycine units in amide linkage with the glycine nitrogen connected to naturally occurring nucleobases or non-naturally occurring nucleobases by a methylene carbonyl linker and said probes capable of hybridizing to 16S or 23S rRNA or rDNA of Neisseria gonorrhoeae or Chlamydia trachomatis are described. PNA is a very stable molecule with very high affinity for nucleic acid allowing a PNA probe to be shorter than conventional nucleic acid probes.

Abstract: PNA probes for detection of Neisseria gonorrhoeae and Chlamydia trachomatis.Specific peptide nucleic acid (PNA) probes for detecting a sexual transmitted disease caused by Neisseria gonorrhoeae or Chlamydia trachomatis comprising N-(2-aminoethyl)glycine units in amide linkage with the glycine nitrogen connected to naturally occurring nucleobases or non-naturally occurring nucleobases by a methylene carbonyl linker and said probes capable of hybridizing to 16S or 23S rRNA or rDNA of Neisseria gonorrhoeae or Chlamydia trachomatis are described.PNA is a very stable molecule with very high affinity for nucleic acid allowing a PNA probe to be shorter than conventional nucleic acid probes.

Abstract: The invention relates to a sensor-system for metal workpieces, especially cast components (casting cleansing), and a cutting sensor for its implementation, and is intended to improve deburring quality rationally and effectively. To this end, relatively coarse burrs are cut off to a predetermined height and the remaining burrs and also the relatively small ones are removed by sensor control in a single pass by a combined tool having sensor cutter and a burr pre-cutter.

Abstract: A piezoelectric precision positioning device for moving an object in three coordinate directions is described, comprising(a) an at least approximately plane-parallel cut piezoelectric disk (5),(b) an electrode arrangement (6, 7, 8, 17), provided with electrical connections (9, 10, 11, 18), on the surfaces parallel to each other, with which three independently controllable electrical fields in the piezoelectric disk (5) can be adjusted,(c) a fork-shaped clamping device (1, 2) which embraces the piezoelectric disk (5), in an electrically insulated manner with respect to the electrode arrangement (6, 7, 8, 17), at at least three pressure points (13, 14, 15, 16), which are situated symmetrically with respect to each other, on the circumferential surface such that(d) one of the electrodes (8) is situated in the open part of the fork-shaped clamping device (1, 2), in which case(e) the object (19) to be positioned is arranged in an electrically insulated manner on an electrode surface (17) in the field region of thi

Abstract: A piston pump for displacing a fluid comprises an adjustable stuffing box, at least one packing ring disposed adjacent to the stuffing box, the fluid exerting pressure on, and the stuffing box abutting against the packing ring, a stuffing box housing for holding the stuffing box, a plunger disposed within the stuffing box and in contact with the packing ring, a throttle ring, a compression spring coaxial with the plunger and disposed between the stuffing box and the throttle ring, the stuffing box engaging the throttle ring telescopically, a clearance remaining therebetween, and a limit stop for making contact with the throttle ring disposed on the stuffing box housing.