Abstract: The invention relates to antibodies to the tumor-associated antigen CD33 and to the use thereof for immunotargeting CD33-positive cells. The antibodies according to the invention are suitable for use in the field of medicine, pharmaceuticals, and biomedical research. According to the invention, the aim is achieved by means of novel anti-CD33 antibodies comprising the complementary determining regions (CDRs) defined in the claim. The antibodies according to the invention are characterized by a high affinity for human CD33, of the order of magnitude of 1010 mol/l. The CDR sequences according to the invention are suitable in particular for producing recombinant fragments (such as scFv fragments or bispecific antibodies) and for immunotargeting, due to the high affinity thereof.

Abstract: A bogie for a locomotive comprising a bogie frame and at least one wheel set including two wheels, a wheel set gear, a wheel set shaft and a wheel set gear housing. A push/pull rod acts on one side of the bogie frame and on the other side of locomotive frame and transfers forces between the two. The gear housing of the wheel set exhibits a recess for the feeding through of the push/pull rod, the recess being bordered by walls which are integral with the remaining housing walls.

Abstract: The present invention relates to a rotary elastic coupling fitted with an inner ring and with an outer ring surrounding the inner ring around the periphery by forming an annular slit. An elastomer is provided in the annular slit, which is vulcanised or glued to the inner ring and to the outer ring and fills up the annular slit substantially or completely. The annular slit is meander-shaped around the periphery of the coupling so that radially outward protrusions of the inner ring undercut radially inward protrusions of the outer ring. Around the periphery of the coupling, a relief opening is provided in the elastomer on both sides of the protrusions of the inner ring and on both sides of the protrusions of the outer ring.

Abstract: The invention relates to a bogie for a locomotive with a bogie frame with at least one wheel set, comprising two wheels, a wheel set gear, a wheel set shaft and a wheel set gear housing; with a push/pull rod, which acts on one side on the bogie frame and on the other side on the locomotive frame and transfers forces between these two. The invention is characterized by the following features: the gear housing of the wheel set exhibits a recess for the feeding through of the push/pull rod; the recess is bordered by walls which are integral with the remaining housing walls.

Abstract: A method for limiting motor-vehicle rollback includes steps in which: the drive direction of the vehicle belonging to the engaged gear step, i.e., transmission step, is determined; the direction of movement of the vehicle is determined; and in the case when the direction of movement is opposite the drive direction, a braking intervention is implemented independently of the driver at the wheels of at least one axle.