Patents by Inventor Michael Barry
Michael Barry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11959090Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: April 28, 2021Date of Patent: April 16, 2024Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Daniel J Altier, Jennifer Kara Barry, Ryan Michael Gerber, Steven D Gruver, Lu Liu, Ute Schellenberger, Jun-Zhi Wei, Weiping Xie, Nasser Yalpani, Genhai Zhu
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Patent number: 11957400Abstract: A surgical device for examination and treatment of a target area. The surgical device includes a shaft portion that extends along a longitudinal axis and that is configured to be inserted into a patient's body, a surgical tool provided within the outer sheath and configured to be movable along the longitudinal axis, and an optical assembly provided at a distal end of the inner shaft, the optical assembly including a light source and an imaging sensor.Type: GrantFiled: April 26, 2023Date of Patent: April 16, 2024Assignee: American Endoscopic Innovations, LLCInventors: James Barry, Israel Franco, Michael Grasso, III, Thomas Ruegg
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Patent number: 11952386Abstract: The present invention relates to compounds of formula I: in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.Type: GrantFiled: February 23, 2021Date of Patent: April 9, 2024Assignee: NOVARTIS AGInventors: Christine Hiu-Tung Chen, Zhuoliang Chen, Michael Dore, Jorge Garcia Fortanet, John William Giraldes, Rajesh Karki, Mitsunori Kato, Matthew J. LaMarche, Lawrence Blas Perez, Martin Sendzik, Troy Douglas Smith, Bakary-Barry Toure, Sarah Williams
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Patent number: 11944770Abstract: An expandable introducer sheath with an interlock dilator. The present technology provides an expandable sheath with a step feature inside its distal opening, and a dilator with an interlock that includes a catch surface configured to engage with the step feature and resist further relative movement so that the body of the dilator is prevented from exiting the distal end of the expandable sheath. This interlocking engagement may allow the dilator to be used to extend and maintain tension on the expandable sheath during insertion into a patient, and then to be retracted from the expandable sheath by pulling the dilator in the opposite direction. The present technology also provides a dilator hub with a spring mechanism configured to achieve and maintain a desired tension on the expandable sheath and to prevent overextension of the expandable sheath when the dilator is being inserted into the expandable sheath.Type: GrantFiled: April 6, 2023Date of Patent: April 2, 2024Assignee: Abiomed, Inc.Inventors: Christopher N. Korkuch, Robert Fishman, Michael Thomas Finnegan, Charles DeLorenzo, Andrew Gentile, Anne Gabrielle McLoughlin, Robert Swierczek, Matthew D'Agostino, Jonathan Barry
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Patent number: 11943876Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.Type: GrantFiled: October 23, 2018Date of Patent: March 26, 2024Assignee: DexCom, Inc.Inventors: Jason Halac, John Charles Barry, Becky L. Clark, Chris W. Dring, John Michael Gray, Kris Elliot Higley, Jeff Jackson, David A. Keller, Ted Tang Lee, Jason Mitchell, Kenneth Pirondini, David Rego, Ryan Everett Schoonmaker, Peter C. Simpson, Craig Thomas Gadd, Kyle Thomas Stewart, John Stanley Hayes
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Patent number: 11931047Abstract: An osteotomy procedure may be performed to correct a misalignment of a bone, such as a bunion deformity. In some examples, the osteotomy procedure involves making a spherical-shaped cut transecting a first metatarsal, thereby forming a first metatarsal portion having a spherical-shaped projection and a second metatarsal portion having a spherical-shaped recess. The method further involves moving the second metatarsal portion in at least two planes relative to the first metatarsal portion, thereby adjusting an anatomical alignment of the second metatarsal portion.Type: GrantFiled: August 2, 2021Date of Patent: March 19, 2024Assignee: Treace Medical Concepts, Inc.Inventors: F. Barry Bays, Joe W. Ferguson, Carlos Eduardo Gil, Tyler Hissong, Danielle Peterson, Sean F. Scanlan, Michael Stedham, Justin Valentine
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Publication number: 20240076688Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: October 17, 2023Publication date: March 7, 2024Applicant: PIONEER HI-BRED INTERNATIONAL, INCInventors: JENNIFER KARA BARRY, CATHERINE J CLARK, RYAN MICHAEL GERBER, AMY LUM, JOHN P MATHIS, AZALEA S ONG, BROOKE PETERSON-BURCH, THOMAS CHAD WOLFE, WEIPING XIE, NASSER YALPANI, XIAOHONG ZHONG
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Publication number: 20240070481Abstract: Various embodiments are provided for configuring optimization problems from one or more sources in a computing environment by a processor. A knowledge graph may be generated from a knowledge domain and one or more data sources. One or more graph pattens may be applied to match one or more entities in the knowledge graph with one or more atomic optimization templates. An optimization problem configured from the one or more atomic optimization templates and a plurality of data may be executed.Type: ApplicationFiled: August 26, 2022Publication date: February 29, 2024Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Michael BARRY, Joern PLOENNIGS, John SHEEHAN, Claudio GAMBELLA
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Publication number: 20240070461Abstract: A method and system for activity classification. A pressure sensor receives input data resulting from physical activity of a subject performing an activity. The input data includes pressure data from at least one pressure sensor, and may include other data acquired through other types of sensors. A deep learning neural network is applied to the input data for identifying the activity. The neural network is trained with reference to training data from a training database. The training data may include empirical data from a database of previous data of corresponding activities, synthesized data prepared from the empirical data or simulated data. The training data may include data from physical activity of the subject being monitored by the system. Different aspects of the neural network may be trained with reference to the training data, and some aspects may be locked or opened depending on the application and the circumstances.Type: ApplicationFiled: November 6, 2023Publication date: February 29, 2024Inventors: CHUN HING CHENG, JULIA BREANNE EVERETT, MICHAEL TODD PURDY, TRAVIS MICHAEL STEVENS, DAVID ALLAN VIBERG, DALE BARRY YEE
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Publication number: 20240026307Abstract: This invention relates to methods and materials for nucleic acid delivery, vaccination, and/or treating cancer. More specifically, methods and materials for nucleic acid delivery, vaccination, and/or treating cancer using one or more recombinant adenoviruses (Ads) as an oncolytic agent are provided.Type: ApplicationFiled: July 17, 2023Publication date: January 25, 2024Inventor: Michael A. BARRY
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Publication number: 20240018546Abstract: This document relates to adenovirus vectors and methods and materials related to using adenovirus vectors. For example, viruses, nucleic acid molecules encoding viruses, cell lines containing viral vectors, and methods for using viruses to deliver nucleic acid to cells in vitro or in vivo are provided. Methods and materials for using adenovirus vectors to induce immune responses and to treat cancer also are provided.Type: ApplicationFiled: September 15, 2023Publication date: January 18, 2024Applicant: Mayo Foundation for Medical Education and ResearchInventors: Michael A. Barry, Eric Weaver
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Publication number: 20230365943Abstract: This invention relates to methods and materials for nucleic acid delivery, vaccination, and/or treating cancer. More specifically, methods and materials for nucleic acid delivery, vaccination, and/or treating cancer using one or more recombinant adenoviruses (Ads) as an oncolytic agent are provided.Type: ApplicationFiled: July 18, 2023Publication date: November 16, 2023Inventor: Michael A. BARRY
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Patent number: 11796382Abstract: An apparatus for sensing acoustic energy in a borehole penetrating the earth includes an optical interrogator and a sensing optical fiber having a length Ls optically coupled to the optical interrogator and configured to sense the acoustic energy to provide sensed acoustic data. The apparatus also includes a reference optical fiber having a length Lr optically coupled to the optical interrogator to provide reference data, wherein the optical interrogator corrects the sensed acoustic data using the reference data to provide corrected sensed acoustic data.Type: GrantFiled: November 21, 2019Date of Patent: October 24, 2023Assignee: BAKER HUGHES OILFIELD OPERATIONS LLCInventors: William Albert Johnston, Alexander Michael Barry
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Patent number: 11795477Abstract: This document relates to adenovirus vectors and methods and materials related to using adenovirus vectors. For example, viruses, nucleic acid molecules encoding viruses, cell lines containing viral vectors, and methods for using viruses to deliver nucleic acid to cells in vitro or in vivo are provided. Methods and materials for using adenovirus vectors to induce immune responses and to treat cancer also are provided.Type: GrantFiled: February 14, 2022Date of Patent: October 24, 2023Assignee: Mayo Foundation for Medical Education and ResearchInventors: Michael A. Barry, Eric Weaver
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Publication number: 20230279428Abstract: This document provides adenovirus vectors and methods and materials related to using adenovirus vectors. For example, adenoviruses for delivering nucleic acid encoding one or more immunogens (e.g., one or more immunogens associated with a pathogen causing an infection) to cells within a mammal such that the mammal produces an effective immune response against the immunogen(s) are provided.Type: ApplicationFiled: August 17, 2021Publication date: September 7, 2023Inventor: Michael A. Barry
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Patent number: 11746334Abstract: This invention relates to methods and materials for nucleic acid delivery, vaccination, and/or treating cancer. More specifically, methods and materials for nucleic acid delivery, vaccination, and/or treating cancer using one or more recombinant adenoviruses (Ads) as an oncolytic agent are provided.Type: GrantFiled: November 21, 2019Date of Patent: September 5, 2023Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventor: Michael A. Barry
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Patent number: 11678347Abstract: A method may be provided. One or more packets from a client may be received, in a block based modulation environment, at one or more switchable antennas of an access point. The access point may have a plurality of switchable antennas. Each switchable antenna may have an antenna state. The plurality of switchable antennas may be switched among such that at least five of the antenna states are sampled. Angle of arrival of the client may be calculated based on the at least five of the antenna states.Type: GrantFiled: January 8, 2021Date of Patent: June 13, 2023Assignee: Cisco Technology, Inc.Inventors: Matthew Aaron Silverman, Ardalan Alizadeh, Michael Barry DeLong, Guru Prasanna Gopalakrishnan
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Patent number: 11485767Abstract: This invention provides methods and materials for treating cancer. The invention encompasses methods and materials for delivering programmed death-ligand 1 (PD-L1) binding compounds and/or compositions containing one or more monovalent or multivalent programmed death-ligand 1 (PD-L1) binding compounds which are administered to a mammal having cancer to treat the mammal. In some cases, a multivalent PD-L1 binding compound can include two or more programmed cell death protein 1 (PD-1) polypeptides (and/or fragments thereof having the ability to bind PD-L1). This invention also provides methods and materials for making multivalent PD-L1 binding compounds and methods and materials for making nucleic acid molecules that encode PD-L1 binding compounds.Type: GrantFiled: April 28, 2020Date of Patent: November 1, 2022Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventor: Michael A. Barry
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Publication number: 20220225317Abstract: A method may be provided. One or more packets from a client may be received, in a block based modulation environment, at one or more switchable antennas of an access point. The access point may have a plurality of switchable antennas. Each switchable antenna may have an antenna state. The plurality of switchable antennas may be switched among such that at least five of the antenna states are sampled. Angle of arrival of the client may be calculated based on the at least five of the antenna states.Type: ApplicationFiled: January 8, 2021Publication date: July 14, 2022Applicant: Cisco Technology, Inc.Inventors: Matthew Aaron Silverman, Ardalan Alizadeh, Michael Barry DeLong, Guru Prasanna Gopalakrishnan
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Publication number: 20220170046Abstract: This document relates to adenovirus vectors and methods and materials related to using adenovirus vectors. For example, viruses, nucleic acid molecules encoding viruses, cell lines containing viral vectors, and methods for using viruses to deliver nucleic acid to cells in vitro or in vivo are provided. Methods and materials for using adenovirus vectors to induce immune responses and to treat cancer also are provided.Type: ApplicationFiled: February 14, 2022Publication date: June 2, 2022Applicant: Mayo Foundation for Medical Education and ResearchInventors: Michael A. Barry, Eric Weaver