Patents by Inventor Michael Barry

Michael Barry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210011098
    Abstract: A magnetometer containing a crystal sensor with solid-state defects senses the magnitude and direction of a magnetic field. The solid-state defects in the crystal sensor absorb microwave and optical energy to transition between several energy states while emitting light intensity indicative of their spin states. The magnetic field alters the spin-state transitions of the solid-state defects by amounts depending on the solid-state defects' orientations with respect to the magnetic field. The optical read out, reporting the spin state of an ensemble of solid-state defects from one particular orientation class, can be used to lock microwave signals to the resonances associated with the spin-state transitions. The frequencies of the locked microwave signals can be used to reconstruct the magnetic field vector.
    Type: Application
    Filed: July 6, 2020
    Publication date: January 14, 2021
    Inventors: Linh M. Pham, Kerry Alexander Johnson, Carson Arthur TEALE, Hannah A. CLEVENSON, Danielle Ann Braje, Christopher Michael MCNALLY, John Francis BARRY
  • Patent number: 10876125
    Abstract: There is provided a non-PCR based method for construction of a DNA recombination fragment with necessary flanking regions homologous to a desired site of genetic manipulation within a target DNA required for recombination-based manipulation of said target DNA, comprising the steps of: A) identifying a desired site of insertion for a genetic element in said target DNA; B) locating an endogenous, native, half-site of a selected restriction endonuclease present upstream of the site within the DNA to be targeted for genetic manipulation and thereby defining the 5? extent of an upstream homology region; C) locating an endogenous, native, half-site of the same selected restriction endonuclease present downstream of the site within the DNA to be targeted for genetic manipulation and thereby defining the 3? extent of a downstream homology region; D) synthesising a flanking region cassette resulting in juxtapositioning of the upstream and downstream half-sites thereby causing formation of complete restriction site for
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: December 29, 2020
    Assignees: UNIVERSITY OF PLYMOUTH, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Michael Jarvis, Aisling Murphy, Peter Barry
  • Patent number: 10863944
    Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: December 15, 2020
    Assignee: DexCom, Inc.
    Inventors: John Michael Gray, Jennifer Blackwell, Paul V. Neale, Justen Deering England, Andrew Joncich, Cameron Brock, Peter C. Simpson, Thomas Metzmaker, Neel Narayan Shah, Mark Douglas Kempkey, Patrick John Castagna, Warren Terry, Jason Halac, Christian Michael Andre George, Daniel E. Apacible, John Charles Barry, Maria Noel Brown Wells, Kenneth Pirondini, Andrew Michael Reinhardt, Jason C. Wong, Remy E. Gagnon, David DeRenzy, Randall Scott Koplin, Alan Baldwin, Young Woo Lee, David A. Keller, Louise Emma van den Heuvel, Carol Wood Sutherland
  • Publication number: 20200339654
    Abstract: This invention provides methods and materials for treating cancer. The invention encompasses methods and materials for delivering programmed death-ligand 1 (PD-L1) binding compounds and/or compositions containing one or more monovalent or multivalent programmed death-ligand 1 (PD-L1) binding compounds which are administered to a mammal having cancer to treat the mammal. In some cases, a multivalent PD-L1 binding compound can include two or more programmed cell death protein 1 (PD-1) polypeptides (and/or fragments thereof having the ability to bind PD-L1). This invention also provides methods and materials for making multivalent PD-L1 binding compounds and methods and materials for making nucleic acid molecules that encode PD-L1 binding compounds.
    Type: Application
    Filed: April 28, 2020
    Publication date: October 29, 2020
    Inventor: Michael A. BARRY
  • Publication number: 20200329324
    Abstract: A micro-electromechanical system (MEMS) transducer assembly includes a transducer including a condenser microphone, an integrated circuit electrically connected to the transducer to receive an output voltage from the transducer, wherein the integrated circuit comprises a test signal generator configured to induce a test acoustic response in the transducer, and an evaluation circuit configured to compare the test acoustic response to a baseline acoustic response to identify a fault in the transducer.
    Type: Application
    Filed: June 26, 2020
    Publication date: October 15, 2020
    Inventors: Peter V. Loeppert, Venkataraman Chandrasekaran, Daryl Barry, Michael Pedersen, Dean Badillo
  • Patent number: 10746016
    Abstract: Downhole fiber optic interrogation systems are described. The systems include a fiber optic control system, a first sensing system, a second sensing system, an optical fiber disposed within a well, and an optical switch arranged between the optical fiber and the first and second sensing systems, wherein the fiber optic control system performs time division multiplex control of the optical switch wherein the first sensing system is operably connected to the optical fiber and the second sensing system is not connected to the optical fiber, and further controls the optical switch such that the second sensing system is operably connected to the optical fiber and the first sensing system is not connected to the optical fiber.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: August 18, 2020
    Assignee: BAKER HUGHES, A GE COMPANY, LLC
    Inventors: Alexander Michael Barry, William Albert Johnston, Ian Mitchell
  • Publication number: 20200255865
    Abstract: This document relates to adenovirus vectors and methods and materials related to using adenovirus vectors. For example, viruses, nucleic acid molecules encoding viruses, cell lines containing viral vectors, and methods for using viruses to deliver nucleic acid to cells in vitro or in vivo are provided. Methods and materials for using adenovirus vectors to induce immune responses and to treat cancer also are provided.
    Type: Application
    Filed: April 30, 2020
    Publication date: August 13, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Michael A. Barry, Eric Weaver
  • Patent number: 10729720
    Abstract: Embodiments are directed to a stable composition comprising stabilized hydrogen peroxide and 2-propanol and applicators configured to store, dispense, and apply such stable compositions. Such compositions may be used to treat skin conditions such as warts, condyloma accuminatum, molluscum contagiosum, acrochordons, seborrheic keratosis, or a combination thereof. Some embodiments also describe take home compositions, in office compositions, over-the-counter compositions, and kits for the use of such compositions.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: August 4, 2020
    Assignee: ACLARIS THERAPEUTICS, INC.
    Inventors: Stuart D. Shanler, Christopher Powala, Christopher Phillips, Brian Beger, Charles Rodney Greenaway Evans, Sian Tiong Lim, Marc Barry Brown, Michael A. Botta, Thomas Nagler
  • Publication number: 20200242199
    Abstract: Various embodiments are provided for managing and interacting with a conversational agent in an internet of things (IoT) environment by a processor. One or more graph patterns may be extracted from a knowledge graph generated from a sensor list containing one or more IoT sensors. One or more conversation patterns and conversation dialogs may be learned from the sensor list and graph patterns. The conversational agent may be automatically configured with the one or more graph patterns, the one or more conversational patterns and conversation dialogs, sensor data and analytics from the one or more IoT sensors according to one or more queries to engage in a conversation dialog with a user.
    Type: Application
    Filed: January 30, 2019
    Publication date: July 30, 2020
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Joern PLOENNIGS, William LYNCH, Fabio LORENZI, Michael BARRY
  • Patent number: 10712408
    Abstract: A magnetometer containing a crystal sensor with solid-state defects senses the magnitude and direction of a magnetic field. The solid-state defects in the crystal sensor absorb microwave and optical energy to transition between several energy states while emitting light intensity indicative of their spin states. The magnetic field alters the spin-state transitions of the solid-state defects by amounts depending on the solid-state defects' orientations with respect to the magnetic field. The optical read out, reporting the spin state of an ensemble of solid-state defects from one particular orientation class, can be used to lock microwave signals to the resonances associated with the spin-state transitions. The frequencies of the locked microwave signals can be used to reconstruct the magnetic field vector.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: July 14, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: Linh M. Pham, Carson Arthur Teale, Hannah A. Clevenson, Kerry Alexander Johnson, Christopher Michael McNally, John Francis Barry, Danielle Ann Braje
  • Publication number: 20200218974
    Abstract: A method and system for activity classification. A pressure sensor receives input data resulting from physical activity of a subject performing an activity. The input data includes pressure data from at least one pressure sensor, and may include other data acquired through other types of sensors. A deep learning neural network is applied to the input data for identifying the activity. The neural network is trained with reference to training data from a training database. The training data may include empirical data from a database of previous data of corresponding activities, synthesized data prepared from the empirical data or simulated data. The training data may include data from physical activity of the subject being monitored by the system. Different aspects of the neural network may be trained with reference to the training data, and some aspects may be locked or opened depending on the application and the circumstances.
    Type: Application
    Filed: August 22, 2018
    Publication date: July 9, 2020
    Applicant: KINETYX SCIENCES INC.
    Inventors: CHUN HING CHENG, JULIA BREANNE EVERETT, MICHAEL TODD PURDY, TRAVIS MICHAEL STEVENS, DAVID ALLAN VIBERG, DALE BARRY YEE
  • Patent number: 10705163
    Abstract: Here we present a solid-state spin sensor with enhanced sensitivity. The enhanced sensitivity is achieved by increasing the T2* dephasing time of the color center defects within the solid-state spin sensor. The T2* dephasing time extension is achieved by mitigating dipolar coupling between paramagnetic defects within the solid-state spin sensor. The mitigation of the dipolar coupling is achieved by applying a magic-angle-spinning magnetic field to the color center defects. This field is generated by driving a magnetic field generator (e.g., Helmholtz coils) with phase-shifted sinusoidal waveforms from current source impedance-matched to the magnetic field generator. The waveforms may oscillate (and the field may rotate) at a frequency based on the precession period of the color center defects to reduce color center defect dephasing and further enhance measurement sensitivity.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: July 7, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: John F. Barry, Danielle A. Braje, Erik R. Eisenach, Christopher Michael McNally, Michael F. O'Keeffe, Linh M. Pham
  • Publication number: 20200213652
    Abstract: The non-linear content scheduling and encoding (recording) system provides a highly automated file-based video-on-demand (VOD) publishing workflow. The system includes content-provider scheduling and broadcast programming for encoding, editing, and distribution of video assets (e.g., episodes). The invention effectively scales VOD production and allows broadcasters to use the same schedule and sources as their traditional playout operation to quickly and efficiently produce VOD deliverables with all the correct metadata. The systems of the invention process content at significantly faster rates than traditional, real-time VOD generation. The systems provide program management and incorporate traffic system ad components within fully integrated VOD publishing. The systems enable automatic retrieval of sources for VOD generation from generic storage, video servers, non-linear editing systems, archiving systems, content delivery systems, data or video tapes, as well as from live video sources.
    Type: Application
    Filed: March 10, 2020
    Publication date: July 2, 2020
    Applicant: SCRIPPS NETWORKS INTERACTIVE, INC.
    Inventors: Graham COLE, Kevin BARRY, Michael DONOVAN, Tim HARTY
  • Publication number: 20200208170
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Application
    Filed: March 5, 2020
    Publication date: July 2, 2020
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: JENNIFER KARA BARRY, RYAN MICHAEL GERBER, LU LIU, AMY LUM, ERIC SCHEPERS, NASSER YALPANI, GENHAI ZHU
  • Patent number: 10699520
    Abstract: A wagering game system and its operations are described herein. In some embodiments, the operations can include detecting that one or more wearable computers are within a proximity range to a wagering game machine. In some examples, the operations further include determining one or more characteristics associated with the one or more wearable computers in response to the detecting that the one or more wearable computers are within the proximity range to the wagering game machine. In some examples, the operations further include providing a feature associated with a wagering game based on the one or more characteristics of the one or more wearable computers.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: June 30, 2020
    Assignee: SG Gaming, Inc.
    Inventors: Michael R. Bytnar, Michael Vincent Dicillo, Patrick M. Gustafson, Jeremy Michael Hornik, Gary John Oswald, Richard Barry Robbins, Nickey C. Shin, Jesse M. Smith, Simon Edward Sunblade, Jamie W. Vann, Muthu Velu, Matthew J. Ward, Steven J. Zoloto, Dale Robert Buchholz, Mark B. Gagner, Craig Joe Sylla
  • Patent number: 10690552
    Abstract: A system and method to determine temperature include an optical fiber and at least two pulse laser sources to transmit light pulses with at least two wavelengths into the optical fiber. The system also includes an optical path length modulator to modulate the optical path length of the optical fiber as the light pulses are transmitted into the optical fiber. At least two photodetectors detect backscatter reflected in the optical fiber, and a processor determines the temperature based on the backscatter.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: June 23, 2020
    Assignee: BAKER HUGHES, A GE COMPANY, LLC
    Inventors: Ian Mitchell, Alexander Michael Barry, William Albert Johnston
  • Publication number: 20200196065
    Abstract: A transducer assembly comprises an acoustic transducer comprising a transducer substrate having a first aperture defined at a first location of the transducer substrate, an acoustic transducer diaphragm disposed on the transducer substrate over the first aperture, and an acoustic transducer back plate disposed on the transducer substrate axially spaced apart from the acoustic transducer diaphragm over the first aperture. The transducer assembly also includes a vibration transducer comprising the transducer substrate having a second aperture defined at a second location thereof, a vibration transducer diaphragm disposed on the transducer substrate over the second aperture, a vibration transducer back plate disposed on the transducer substrate axially spaced apart from the vibration transducer back plate over the second aperture, and an anchor coupled to one of the vibration transducer diaphragm or the vibration transducer back plate, the anchor disposed in the second aperture and suspended freely therewithin.
    Type: Application
    Filed: December 11, 2019
    Publication date: June 18, 2020
    Applicant: Knowles Electronics, LLC
    Inventors: Michael Pedersen, John Albers, Daryl Barry, Venkataraman Chandrasekaran, Sarmad Qutub, Joshua Watson
  • Publication number: 20200181168
    Abstract: The present invention relates to compounds of formula I: in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Application
    Filed: May 21, 2019
    Publication date: June 11, 2020
    Inventors: Christine Hiu-Tung Chen, Zhuoliang Chen, Michael Dore, Jorge Garcia Fortanet, John William Giraldes, Rajesh Karki, Mitsunori Kato, Matthew J. LaMarche, Lawrence Blas Perez, Martin Sendzik, Troy Douglas Smith, Bakary-Barry Toure, Sarah Williams
  • Publication number: 20200157510
    Abstract: This invention relates to methods and materials for nucleic acid delivery, vaccination, and/or treating cancer. More specifically, methods and materials for nucleic acid delivery, vaccination, and/or treating cancer using one or more recombinant adenoviruses (Ads) as an oncolytic agent are provided.
    Type: Application
    Filed: November 21, 2019
    Publication date: May 21, 2020
    Inventor: Michael A. BARRY
  • Patent number: 10653721
    Abstract: Embodiments are directed to a stable composition comprising stabilized hydrogen peroxide and 2-propanol and applicators configured to store, dispense, and apply such stable compositions. Such compositions may be used to treat skin conditions such as warts, condyloma accuminatum, molluscum contagiosum, acrochordons, seborrheic keratosis, or a combination thereof. Some embodiments also describe take home compositions, in office compositions, over-the-counter compositions, and kits for the use of such compositions.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: May 19, 2020
    Assignee: ACLARIS THERAPEUTICS, INC.
    Inventors: Stuart D. Shanler, Christopher Powala, Christopher Phillips, Brian Beger, Charles Rodney Greenaway Evans, Sian Tiong Lim, Marc Barry Brown, Michael A. Botta, Thomas Nagler