Abstract: An electronic chip is disclosed. In one example, the electronic chip comprises a substrate comprising a central portion and an edge portion around at least part of the central portion. An active region is arranged in the central portion. A crack guiding structure combined with a crack stop structure is provided, both being arranged in the edge portion.

Abstract: The invention relates to a nanostructured delivery system comprising at least one polymer and/or at least one lipid and at least one polymethine dye, for use in treating a subject suffering from an adenocarcinoma comprising adenocarcinoma cells with a gene expression alteration in one or more SLCO genes. Therein, the at least one polymethine dye mediates targeted transport of the nanostructured delivery system into said adenocarcinoma cells. The invention relates further to a pharmaceutical composition comprising the nanostructured delivery system. The invention also relates to a method for targeted transport into neoplastic tissue using the nanostructured delivery system and to a use of the nanostructured delivery system or of the pharmaceutical composition of the invention for detection by fluorescence based on the accumulation of said system or composition in neoplastic tissues or cells.

Abstract: The subject disclosure presents systems and computer-implemented methods for determining an acoustic time-of-flight (TOF) of sound waves through a sample material with greater accuracy and in a more repeatable fashion, by invoking one or more of an envelope generation for an error function, fitting a non-linear curve to an ultrasound frequency sweep, or performing a clustered piece-wise linear regression on individual linear parts of the ultrasonic frequency sweep. The systems and methods are useful for, among other things, monitoring diffusion of fluids through porous materials, such as tissue samples.

Abstract: A portion of a vertical structure is determined for inspection by an unmanned aerial vehicle. A flight plan including safe locations around the vertical structure is determined. Each of the safe locations is associated with a respective column of waypoints. The unmanned aerial vehicle navigates according to the flight plan by navigating to a first safe location of the safe locations, navigating vertically along a first column associated with the first safe location, activating sensors to obtain respective sensor information at at least some of the waypoints associated with the first safe location, navigating to a second safe location of the safe locations, navigating vertically along a second column associated with the second safe location, and activating the sensors to obtain respective sensor information at at least some of the waypoints associated with the second safe location.

Abstract: Various shaped abrasive particles are disclosed. Each shaped abrasive particle includes a body having at least one major surface and a side surface extending from the major surface.

Abstract: The present invention relates to an oral thin film comprising a polymer matrix in the form of a solidified foam having voids, wherein the polymer matrix contains at least one active pharmaceutical ingredient, at least one first polymer which comprises a water-soluble polymer and at least one second polymer which comprises a mucoadhesive polymer having a number-average molecular weight of equal to or greater than 100,000 g/mol, a method for producing the oral thin film, and the use of such an oral thin film as a medicament.

Abstract: A hub bearing assembly includes a housing with a vertical bore, a bearing outer ring disposed within the bore and coupled with the housing and a bearing inner ring disposed within the bearing outer ring and having a central bore configured to receive a portion of the shaft. A set of rolling elements are disposed between the bearing outer and inner rings. An upper seal is disposed within the housing bore externally of the outer ring and includes an annular elastomeric seal body and a garter spring biasing a seal lip radially inwardly. A lower seal is disposed between the bearing outer and inner rings. Either the bearing inner ring is sized such that upper seal is disposed about the bearing inner ring or the hub bearing assembly further comprises an annular spacer disposed within the upper seal and adjacent to the upper axial end of the bearing inner ring.

Abstract: A tenter-clip carriage for a stretching system comprises a longitudinal direction (LR) and a transverse direction and a clip body having a clamping device. The tenter-clip carriage comprises fastening portions in order to fasten the tenter-clip carriage to a partial chain portion of a conveyor chain arrangement of the stretching system. The tenter-clip carriage comprises at least one stabilising roller or at least one stabilising sliding element. The at least one stabilising roller or the at least one stabilising sliding element is, by means of a guide device: a) held directly on the tenter-clip carriage; or b) held indirectly on the tenter-clip carriage via a pin that connects two chain segments of the partial chain portion of the conveyor chain arrangement to one another and, specifically, unaffected by the feed and drive forces acting on the tenter-clip carriage or the partial chain portion to move the tenter-clip carriage and/or the partial chain portion.

Abstract: Systems and methods for processing emergency communications are provided. A system may receive an emergency communication initiated by an emergency communicator. The system may detect a data field action in response to an emergency receiver entering a data input based on the emergency communication. The system may capture a timestamp of when the data field action occurred. The system may generate a communication snippet based on the action timestamp and a snippet length. The communication snippet may be configured to provide context from the emergency communication to the data input. The system may transmit the communication snippet and the data input to an emergency responder.

Abstract: The present invention relates to pharmaceutical combinations comprising a compound of formula T or a pharmaceutically acceptable salt thereof and cyclo(-Tyr-His-Ala-Cys-Ser-Ala-DPro-Dab-Arg-Tyr-Cys-Tyr-Gln-Lys-DPro-Pro-) having a disulfide bond between Cys4 and Cys11 or a pharmaceutically acceptable salt thereof and their use in a method for the prevention, delay of progression or treatment of cancer in a subject.

Abstract: Systems and methods for processing emergency communications are provided. A system may receive an emergency communication initiated by an emergency communicator. The system may detect a data field action in response to an emergency receiver entering a data input based on the emergency communication. The system may capture a timestamp of when the data field action occurred. The system may generate a communication snippet based on the action timestamp and a snippet length. The communication snippet may be configured to provide context from the emergency communication to the data input. The system may transmit the communication snippet and the data input to an emergency responder.

Abstract: A carrier component for a vehicle application, formed by two half-shells that are welded to one another at contact sides. When assembling the two half-shells for joining same at the contact sides, in a position in which the two half-shells are arranged above one another, the point of contact of the lower half-shell protrudes in relation to the external closed side of the other half-shell. The point of contact of one of the two half-shells protrudes inward in relation to the internal closed side of the other half-shell. A method for producing a carrier component from two half-shells is also disclosed.

Abstract: The present invention relates to new uses and dosage regimens of inhibitors of the Notch signalling pathway such as 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine for the treatment of tumours.

Abstract: Systems and methods for processing emergency communications are provided. A system may receive an emergency communication initiated by an emergency communicator. The system may detect a data field action in response to an emergency receiver entering a data input based on the emergency communication. The system may capture a timestamp of when the data field action occurred. The system may generate a communication snippet based on the action timestamp and a snippet length. The communication snippet may be configured to provide context from the emergency communication to the data input. The system may transmit the communication snippet and the data input to an emergency responder.

Abstract: A method for changing software data of a field device is disclosed. In an embodiment, the field device has, in or on a housing, a device code that can be optically detected using a mobile device. An embodiment of the method includes detecting a first device code with a reader unit of the mobile device, accessing primary device data of the field device by the mobile device, and converting the primary device data to secondary device data. The embodiment further includes detecting a second device code and subsequently transmitting the secondary device data to the field device. The second device code may be the same as or different from the first device code. The disclosed embodiments furthermore comprise an associated system.

Abstract: A frictional damper is designed with a tubular housing having a longitudinal axis, with a tappet, which is displaceable in the housing along the longitudinal axis and is led out at an open end of the housing, with a frictional element lying against the tappet and with a cap attached to the open end of the housing with axial prestressing relative to the longitudinal axis.

Abstract: The organic small molecule 4,4?,4?,4??-(5,5-dimethoxycyclopenta-1,3-diene-1,2,3,4-tetrayl)tetrakis(N,N-bis(4-methoxyhenyl)aniline (CPDA 1), shows electrochemical properties very close to spiro-OMeTAD indicating a high compatibility with PSC systems for its use as a hole transport material (HTM). The implementation of the cyclopentadiene dimethyl acetale core helps to red shift the absorption onset of the films as well as provide a flexible spatial configuration of the molecule, which is essential for optimum film forming properties. Transient and steady state emission analysis as well as hole mobility measurements indicate that the new HTM allows a better charge extraction, transport and separation than the spiro-OMeTAD reference compound. PSCs based on the new CPDA 1 show a PCE close to 23% with lower hysteresis than its analogue. Stability studies performed under ambient, heated and humid conditions all showed that CPDA 1 is over-performing spiro-OMeTAD.

Abstract: Methods and systems are provided for controlling an EGR valve and VGT vanes during engine braking. In one example, a method may include during an engine braking event in an engine, coordinating adjustments of both of a cross-sectional area of an inlet of a turbine and an opening of a valve of an exhaust gas recirculation (EGR) system to achieve a desired braking power and to maintain an exhaust system temperature above a threshold temperature during the engine braking event.

Abstract: Methods and systems are provided for controlling an EGR valve and VGT vanes during engine braking. In one example, a method may include during an engine braking event in an engine, coordinating adjustments of both of a cross-sectional area of an inlet of a turbine and an opening of a valve of an exhaust gas recirculation (EGR) system to achieve a desired braking power and to maintain an exhaust system temperature above a threshold temperature during the engine braking event.

Abstract: An accommodation system for an accommodation space for storing rollable containers in a vehicle. After a front container, which is arranged at the insertion opening, has been removed in the conventional manner, it is possible, through the use of the accommodation system, to remove the rear container which is arranged considerably spaced apart from the insertion opening in the interior of the accommodation space. For this purpose, a rail system is provided in the floor region of the accommodation space. A transfer plate is movable on the rail system in the floor region of the accommodation space and can assume a storage position and a removal position for the rear container.