Abstract: The present disclosure provides for a method of monitoring the mean arterial pressure of a patient having a blood pump. The method may involve identifying a segment of time associated with diastole of the patient's cardiac cycle, determining a first parameter of the blood pump corresponding to the identified segment of time, and estimating the mean arterial pressure of the patient based at least in part on the first parameter.

Abstract: Methods and devices are provided for securing suture to tissue. In one exemplary embodiment, the implant can include an intermediate portion, a first radially expandable portion extending from the intermediate portion, and a second radially expandable portion extending from the intermediate portion. The implant can be configured to be inserted through a delivery device in a first configuration and deployed into a hole formed in tissue in a second configuration such that the intermediate portion is positioned within the hole. A suture can be inserted through a passageway of the intermediate portion positioned within the hole, and the suture can be tensioned to secure the tissue to bone.

Abstract: The present invention provides novel antibodies to human CXCR4 with high affinity to the target and the ability to act potently as antagonists. The antibodies disclosed herein bind to a diverse range of epitopes.

Abstract: The present disclosure provides for a method, control device, and implantable system, for acquiring a plurality of flow rate data points over time, each data point indicative of a flow rate of blood through the pump, calculating, based on the plurality of acquired flow rate data points, a value characterizing one or more features of a waveform formed from the plurality of flow rate data points; and determining, based on the value, the presence or absence of a suction condition in the pump.

Abstract: In one aspect, a method includes performing a mapping on bits to form a complex data symbol, applying a frequency rotation mask to the complex data symbol based on a polynomial phase, performing an inverse discrete Fourier transform (IDFT) after applying the frequency rotation mask, applying a time domain window after performing the IDFT, converting digital data to analog data after applying the time window and transmitting the analog data as an analog signal.

Abstract: The present invention provides novel antibodies to human ADORA2A.

Abstract: The present invention provides novel antibodies to human CXCR4 with high affinity to the target and the ability to act potently as antagonists. The antibodies disclosed herein bind to a diverse range of epitopes.

Abstract: Honeycomb ceramic wall flow filters exhibiting reduced plug depth variability, produced by introducing flowable ceramic plugging cements into the ends of selected channels in the honeycombs and wherein the ceramic plugging cements consist of shear-conditioned mixtures exhibiting reduced viscosity differentials.

Abstract: In one aspect, a method includes performing a mapping on bits to form a complex data symbol, applying a frequency rotation mask to the complex data symbol based on a polynomial phase, performing an inverse discrete Fourier transform (IDFT) after applying the frequency rotation mask, applying a time domain window after performing the IDFT, converting digital data to analog data after applying the time window and transmitting the analog data as an analog signal.

Abstract: A system for delivering an expandable implant into the vasculature of a patient, including an elongated core element having a proximal end accessible exterior to the patient and a distal end including at least one feature for engaging a proximal portion of the implant in a collapsed state. The system further includes an expansion limiter having an inner diameter and a length sufficient to cover the proximal portion of the implant and to retain the proximal portion in the collapsed state, and at least one elongated member having a distal end connected to the expansion limiter and a proximal end accessible exterior to the patient to enable proximal movement of the expansion limiter to release the implant.

Abstract: Methods and devices are provided for securing suture to tissue. In one exemplary embodiment, the implant can include an intermediate portion, a first radially expandable portion extending from the intermediate portion, and a second radially expandable portion extending from the intermediate portion. The implant can be configured to be inserted through a delivery device in a first configuration and deployed into a hole formed in tissue in a second configuration such that the intermediate portion is positioned within the hole. A suture can be inserted through a passageway of the intermediate portion positioned within the hole, and the suture can be tensioned to secure the tissue to bone.

Abstract: A system for delivering an expandable implant into the vasculature of a patient, including an elongated core element having a proximal end accessible exterior to the patient and a distal end including at least one feature for engaging a proximal portion of the implant in a collapsed state. The system further includes an expansion limiter having an inner diameter and a length sufficient to cover the proximal portion of the implant and to retain the proximal portion in the collapsed state, and at least one elongated member having a distal end connected to the expansion limiter and a proximal end accessible exterior to the patient to enable proximal movement of the expansion limiter to release the implant.

Abstract: Honeycomb ceramic wall flow filters exhibiting reduced plug depth variability, produced by introducing flowable ceramic plugging cements into the ends of selected channels in the honeycombs and wherein the ceramic plugging cements consist of shear-conditioned mixtures exhibiting reduced viscosity differentials.

Abstract: Analytes and ligands for detecting animal byproduct in agricultural samples such as animal feed to minimize the transmission of prion pathogens into food products consumed by humans. The analyte is a component of rendered animal byproduct such as meat and bone meal (MBM). An antibody specific for the analyte is produced by immunizing an animal with MBM or an immunogenic component of MBM that is found in rendered animal product.

Abstract: Analytes and ligands for detecting animal byproduct in agricultural samples such as animal feed to minimize the transmission of prion pathogens into food products consumed by humans. The analyte is a component of rendered animal byproduct such as meat and bone meal (MBM). An antibody specific for the analyte is produced by immunizing an animal with MBM or an immunogenic component of MBM that is found in rendered animal product.