Patents by Inventor Michael C. Chen
Michael C. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180023108Abstract: The invention relates to the use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of synthesizing nucleic acids, and to the use of kits comprising said enzymes in a method of nucleic acid synthesis. The invention also relates to the use of terminal deoxynucleotidyl transferases and 3?-blocked nucleotide triphosphates in a method of template independent nucleic acid synthesis.Type: ApplicationFiled: February 10, 2016Publication date: January 25, 2018Inventors: Michael C. CHEN, Radu A. LAZAR, Jiahao HUANG, Gordon R. MCINROY
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Publication number: 20180016609Abstract: The invention relates to a method of nucleic acid synthesis comprising the use of 3?-O-azidomethyl blocked nucleotide triphosphates which comprises the step of adding a capping group to any uncleaved 3?-O-azidomethyl groups and to the use of kits comprising said capping groups in a method of nucleic acid synthesis. The invention also relates to capped nucleotide triphosphates and 3?-O-azidomethyl capping groups.Type: ApplicationFiled: March 3, 2016Publication date: January 18, 2018Inventors: Michael C. Chen, Radu A. Lazar, Jiahao Huang, Gordon R. McInroy
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Patent number: 8052691Abstract: The invention relates to a device for attaching fixation elements to bone, having a longitudinal member with a channel extending therein adapted for receiving at least one fixation element. A shaft extends within the channel and is positioned coaxially within at least a portion of the longitudinal member and at least a portion of the shaft is retained within the longitudinal member and a distal end of the shaft is configured and adapted to contact at least a portion of the fixation element received within the longitudinal member. A spring is positioned adjacent the shaft for resiliently biasing the shaft in an axial direction and the shaft is moveable with respect to the longitudinal member to drive the fixation element into bone.Type: GrantFiled: November 18, 2004Date of Patent: November 8, 2011Assignee: Synthes USA, LLCInventors: Ralph Fritz Zwirnmann, Michael C. Chen
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Publication number: 20110007637Abstract: In one embodiments, a method includes determining a current connection status of a first wireless device with respect to one or more second wireless devices configured to communicate wirelessly by a particular wireless communication protocol. The current connection status of the first wireless device potentially being that the first wireless device has scanned for and found one or more available ones of the second wireless devices to connect wirelessly to but has not yet having established a wireless connection to any one of them or potentially being that the first wireless device is currently attempting to establish a wireless connection to one of the available ones of the second wireless devices.Type: ApplicationFiled: July 7, 2009Publication date: January 13, 2011Applicant: Cisco Technology, Inc.Inventors: Michael C. Chen, Gregory S. Mercurio, Eric M. Trehus
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Patent number: 7606926Abstract: A system and method are disclosed in which an initiating caller using a station connected to a data network receives advertisement information while waiting for a call to complete between the station and the receiving party. The station connects with a server that can access a database storing a plurality of advertisement information. The station includes a user interface, which allows the caller to interact with the station, and a flow controller, which monitors the bandwidth available to receive information from the server system.Type: GrantFiled: November 12, 2004Date of Patent: October 20, 2009Assignee: Cisco Technology, Inc.Inventors: Michael C. Chen, Jan Fandrianto, Steve Toteda
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Patent number: 7585669Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.Type: GrantFiled: May 14, 2007Date of Patent: September 8, 2009Assignee: Synergy America, Inc.Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
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Publication number: 20080199952Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.Type: ApplicationFiled: May 14, 2007Publication date: August 21, 2008Applicant: Synergy America, Inc.Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
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Patent number: 7217791Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.Type: GrantFiled: November 6, 2003Date of Patent: May 15, 2007Assignee: Synergy America, Inc.Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
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Patent number: 7147641Abstract: The invention relates to a device for attaching fixation elements to bone, having a longitudinal member with a channel extending therein adapted for receiving at least one fixation element. A shaft extends within the channel and is positioned coaxially within at least a portion of the longitudinal member and at least a portion of the shaft is retained within the longitudinal member and a distal end of the shaft is configured and adapted to contact at least a portion of the fixation element received within the longitudinal member. The longitudinal member is moveable with respect to the shaft to drive the fixation element into bone.Type: GrantFiled: May 30, 2001Date of Patent: December 12, 2006Inventor: Michael C. Chen
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Patent number: 7092380Abstract: A method and system are disclosed in which an Internet subscriber can establish real-time voice conversations over the Internet. By performing a call negotiation scheme to identify and locate the other calling party, an Internet telephone can establish a voice communication channel over the Internet to a telephony or computer device.Type: GrantFiled: April 5, 2000Date of Patent: August 15, 2006Assignee: Cisco Technology, Inc.Inventors: Michael C. Chen, Jan Fandrianto, Chun-Chau Lin, Michael P. Sadikun, Budi Sutardja, Ramah Sutardja
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Patent number: 7027456Abstract: A system and method is disclosed for providing dynamic multimedia jitter buffer adjustment for packet-switched networks. The system temporarily stores an amount of incoming data, which is dynamically adjustable, for an amount of time before sending the data out in a more even stream. The system includes a decoder clock, a jitter buffer, a network jitter statistics collector, and a jitter buffer controller. The decoder clock indicates the arrival-time of the data at the system, while the network jitter statistics collector collects the playback-time of that data. By comparing the arrival-time and the playback-time, the jitter buffer controller determines whether the data arrived on schedule. Accordingly, the depth of the jitter buffer can be adjusted to accommodate the late or early arriving data.Type: GrantFiled: February 22, 2005Date of Patent: April 11, 2006Assignee: Cisco Technology, Inc.Inventor: Michael C. Chen
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Patent number: 6859460Abstract: A system and method is disclosed for providing dynamic multimedia jitter buffer adjustment for packet-switched networks. The system temporarily stores an amount of incoming data, which is dynamically adjustable, for an amount of time before sending the data out in a more even stream. The system includes a decoder clock, a jitter buffer, a network jitter statistics collector, and a jitter buffer controller. The decoder clock indicates the arrival-time of the data at the system, while the network jitter statistics collector collects the playback-time of that data. By comparing the arrival-time and the playback-time, the jitter buffer controller determines whether the data arrived on schedule. Accordingly, the depth of the jitter buffer can be adjusted to accommodate the late or early arriving data.Type: GrantFiled: May 31, 2000Date of Patent: February 22, 2005Assignee: Cisco Technology, Inc.Inventor: Michael C. Chen
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Patent number: 6857024Abstract: A system and method are disclosed in which an initiating caller using a station connected to a data network receives advertisement information while waiting for a call to complete between the station and the receiving party. The station connects with a server that can access a database storing a plurality of advertisement information. The station includes a user interface, which allows the caller to interact with the station, and a flow controller, which monitors the bandwidth available to receive information from the server system.Type: GrantFiled: August 21, 2000Date of Patent: February 15, 2005Assignee: Cisco Technology, Inc.Inventors: Michael C. Chen, Jan Fandrianto, Steve Toteda
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Publication number: 20040213803Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.Type: ApplicationFiled: November 6, 2003Publication date: October 28, 2004Inventors: Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
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Patent number: 6809168Abstract: The co-polymerization reaction of one or more olefin monomers, such as propylene, with &agr;,&ohgr;-diene units and the resulting copolymers are provided. More specifically, the copolymer may have from 90 to 99.999 weight percent of olefins and from 0.001 to 2.000 weight percent of &agr;,&ohgr;-dienes. The copolymer may have a weight average molecular weight in the range from 50,000 to 2,000,000, a crystallization temperature in the range from 115° C. to 135° C. and a melt flow rate in the range from 0.1 dg/min to 100 dg/min. These copolymers may be employed in a wide variety of applications, the articles of which include, for example, films, fibers, such as spunbonded and meltblown fibers, fabrics, such as nonwoven fabrics, and molded articles. The copolymer may further include at least two crystalline populations.Type: GrantFiled: April 2, 2003Date of Patent: October 26, 2004Assignee: ExxonMobil Chemical Patents Inc.Inventors: Pawan Kumar Agarwal, Weiqing Weng, Aspy K. Mehta, Armenag H. Dekmezian, Main Chang, Rajan K. Chudgar, Olivier Jean Georjon, Chon-Yie Lin, Michael C. Chen, Galen C. Richeson, Palanisamy Arjunan
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Patent number: 6784269Abstract: This invention relates to propylene homopolymer compositions obtained from metallocene catalysis wherein the polymer has a molecular weight distribution (Mw/Mn) in the range of from 4.0 to 20.0. The propylene homopolymer composition may be prepared in a multiple stage polymerization process using the same metallocene component in at least two stages. The composition may comprise isotactic homopolymer in one embodiment, and have a hexane extractables of less than 2 wt % in one embodiment. The composition is useful in making films.Type: GrantFiled: June 20, 2002Date of Patent: August 31, 2004Assignee: ExxonMobil Chemical Patents Inc.Inventors: Chon Y. Lin, Michael C. Chen, Aspy K. Mehta, Rajan K. Chudgar
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Publication number: 20040087749Abstract: The co-polymerization reaction of one or more olefin monomers, such as propylene, with &agr;,&ohgr;-diene units and the resulting copolymers are provided. More specifically, the copolymer may have from 90 to 99.999 weight percent of olefins and from 0.001 to 2.000 weight percent of &agr;,&ohgr;-dienes. The copolymer may have a weight average molecular weight in the range from 50,000 to 2,000,000, a crystallization temperature in the range from 115° C. to 135° C. and a melt flow rate in the range from 0.1 dg/min to 100 dg/min. These copolymers may be employed in a wide variety of applications, the articles of which include, for example, films, fibers, such as spunbonded and meltblown fibers, fabrics, such as nonwoven fabrics, and molded articles. The copolymer may further include at least two crystalline populations.Type: ApplicationFiled: April 2, 2003Publication date: May 6, 2004Inventors: Pawan Kumar Agarwal, Weiqing Weng, Aspy K. Mehta, Armenag H. Dekmezian, Main Chang, Rajan K. Chudgar, Armenag H. Dekmezian, Olivier Jean Georjon, Chon-Yie Lin, Michael C. Chen, Galen C. Richeson, Palanisamy Arjunan
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Publication number: 20030125750Abstract: The invention relates to a device for attaching fixation elements to bone, having a longitudinal member with a channel extending therein adapted for receiving at least one fixation element. A shaft extends within the channel and is positioned coaxially within at least a portion of the longitudinal member and at least a portion of the shaft is retained within the longitudinal member and a distal end of the shaft is configured and adapted to contact at least a portion of the fixation element received within the longitudinal member. A spring is positioned adjacent the shaft for resiliently biasing the shaft in an axial direction and the shaft is moveable with respect to the longitudinal member to drive the fixation element into bone.Type: ApplicationFiled: November 5, 2002Publication date: July 3, 2003Inventors: Ralph Fritz Zwirnmann, Michael C. Chen
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Patent number: 6583227Abstract: This invention relates generally to crystalline propylene polymers, to methods for their production and to methods for their use in film applications. Specifically, this invention relates to crystalline propylene polymers comprising both propylene homopolymer and propylene copolymer. The compositions are prepared using metallocene catalyst systems comprising at least two metallocenes in a polymerization process that involves the sequential or parallel polymerization of propylene homopolymer and copolymer using propylene with a small amount of comonomer, preferably ethylene. The polymerization is catalyzed by a dual metallocene catalyst system. The resulting polymers have a broad, bimodal molecular weight distribution. The resulting polymers are excellent for use in the production of biaxially oriented films or non-oriented films.Type: GrantFiled: March 6, 2001Date of Patent: June 24, 2003Assignee: ExxonMobil Chemical Patents Inc.Inventors: Aspy K. Mehta, Michael C. Chen, James J. McAlpin, Anthony N. Speca, Kelly Tormaschy, Chon Y. Lin
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Patent number: 6576306Abstract: This invention relates generally to crystalline propylene polymers, to methods for their production and to methods for their use in film applications. Specifically, this invention relates to crystalline propylene polymers comprising both propylene homopolymer and propylene copolymer. The compositions are prepared using metallocene catalyst systems comprising at least two metallocenes in a polymerization process that involves the sequential or parallel polymerization of propylene homopolymer and copolymer using propylene with a small amount of comonomer, preferably ethylene. The polymerization is catalyzed by a dual metallocene catalyst system. The resulting polymers have a broad, bimodal molecular weight distribution. The resulting polymers are excellent for use in the production of biaxially oriented films or non-oriented films.Type: GrantFiled: March 6, 2001Date of Patent: June 10, 2003Assignee: ExxonMobil Chemical Patents Inc.Inventors: Aspy K. Mehta, Michael C. Chen, James J. McAlpin, Anthony N. Speca, Kelly Tormaschy, Chon Y. Lin