Abstract: A bodywork structure for a passenger vehicle includes a bodywork shell construction with two longitudinal girders and a flexible crossmember device attached to the two longitudinal girders. The flexible crossmember device has a first flexible crossmember and two energy absorption elements where the two energy absorption elements are respectively fixed to the two longitudinal girders and the first flexible crossmember is connected to the two longitudinal girders via the two energy absorption elements. A support framework is disposed between the two longitudinal girders and has a second flexible crossmember that is at least indirectly connected to the two longitudinal girders and is convexly curved in a direction of the first flexible crossmember. The support framework has a load divider disposed between the first flexible crossmember and the second flexible crossmember in the longitudinal direction of the passenger vehicle and extending in the transverse direction of the passenger vehicle.

Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that specifically bind and inhibit TRENT-1 signaling, wherein the antibodies do not bind to one or more Fc?Rs and do not induce the myeloid cells to produce inflammatory cytokines. Also provided are uses of such antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of autoimmune diseases.

Abstract: An energy absorption component for a motor vehicle includes an energy absorption element that has a longitudinal element with first and second support regions that support the longitudinal element on a bumper crossmember of the motor vehicle and on a shell construction element of the motor vehicle, respectively. A strengthening element is disposed on an outside of the longitudinal element and has first and second support regions that support the strengthening element on the bumper crossmember and on the shell construction element, respectively. An end of the first support region of the strengthening element is disposed apart from an end of the first support region of the longitudinal element by a first distance and an end of the second support region of the strengthening element is disposed apart from an end of the second support region of the longitudinal element by a second distance.

Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that specifically bind and inhibit TRENT-1 signaling, wherein the antibodies do not bind to one or more Fc?Rs and do not induce the myeloid cells to produce inflammatory cytokines. Also provided are uses of such antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of autoimmune diseases.

Abstract: A system may include one or more processors disposed within a management network, where the management network has computing resources dedicated to an end-user network. The end-user network may include agent instances and one or more servers associated with the end-user network. The one or more servers are operable to: (i) receive communications to the end-user network, and (ii) assign agent instances to service the communications. The one or more processors may be configured to perform one or more tasks. These tasks may include receiving data associated with the processes of the one or more servers, where the processes relate to the end-user network. The tasks may also include determining, based on a specification, an operation to be performed by the one or more servers, where the specification is defined by the end-user network and comprises a logical directive including at least one condition that, if satisfied by the received data, define the operation.

Abstract: A system may include one or more processors disposed within a management network, where the management network has computing resources dedicated to an end-user network. The end-user network may include agent instances and one or more servers associated with the end-user network. The one or more servers are operable to: (i) receive communications to the end-user network, and (ii) assign agent instances to service the communications. The one or more processors may be configured to perform one or more tasks. These tasks may include receiving data associated with the processes of the one or more servers, where the processes relate to the end-user network. The tasks may also include determining, based on a specification, an operation to be performed by the one or more servers, where the specification is defined by the end-user network and comprises a logical directive including at least one condition that, if satisfied by the received data, define the operation.

Abstract: A front-end structure arrangement of a bodyshell of a motor vehicle includes a front-end structure which has a first longitudinal member and a second longitudinal member where the first longitudinal member and the second longitudinal member are connected to one another. An assembly carrier is fastened to the bodyshell, extends in a free space between the first longitudinal member and the second longitudinal member, and has a first side region that runs laterally along the first longitudinal member to form a first gap and has a second side region that runs laterally along the second longitudinal member to form a second gap. A first supporting element of a protective device is disposed in the first gap and runs laterally along the first longitudinal member to form a third gap between the first supporting element and the first longitudinal member. The third gap is smaller than the first gap.

Abstract: The present invention relates to devices and methods for detecting the amount (degree, extent) of material coating a medical device or substrate, in particular the present invention relates to devices and methods for detecting the amount of vaccine material coating a microarray patch.

Abstract: An electronic connector panel that mounts on a wall of a device housing. The electronic connector panel has at least two integrated electric connectors, the housings of which are interconnected by a common mounting plate. There is at least one contact member for each electric connector as well as at least one contact element per contact member. A flat sealing member with openings for both connectors may be used between the connector panel and the wall of the device.

Abstract: A container assembly is provided comprising a container body, a stopper member removably attachable to the container to seal a container aperture thereof, and a thermal insulation member removably attachable to an upper body portion of the container body. The thermal insulation member has a sidewall extending downwardly from an upper portion and defining a downwardly opening cavity within which the upper body portion and the stopper are positioned. The sidewall and the upper portion of the thermal insulation member each include an inner wall and an outer wall spaced apart from the inner wall. An insulation chamber is disposed between the inner and outer walls. The thermal insulation member includes an engagement portion adapted to engage with a corresponding engagement portion of the upper body portion to removably attach the thermal insulation member thereto.

Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that specifically bind and inhibit TREM-1 signaling, wherein the antibodies do not bind to one or more Fc?Rs and do not induce the myeloid cells to produce inflammatory cytokines. Also provided are uses of such antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of autoimmune diseases.

Abstract: The present invention relates to applicators for administering microprojection arrays to skin and methods of administering microprojection arrays.

Abstract: A method of treating a cognitive or neurodegenerative disease, comprising administering to a patient in need of such treatment an effective amount of an anti-N3pGlu Abeta antibody, an anti-Abeta antibody, or an antibody fragment that binds Amyloid beta and is covalently attached to a polyethylene glycol molecule, in combination with an effective amount of an anti-Tau antibody.

Abstract: The present invention relates to devices and methods for detecting the amount (degree, extent) of material coating a medical device or substrate, in particular the present invention relates to devices and methods for detecting the amount of vaccine material coating a microarray patch.

Abstract: A system may include one or more processors disposed within a management network. An end-user network may contain agent instances and one or more servers, where the one or more servers are operable to: (i) receive communications to the end-user network, and (ii) assign agent instances to service the communications. The one or more processors may be configured to perform one or more tasks. These tasks may include receiving, from the end-user network, data associated with the processes of the one or more servers; determining, based on a specification, operations to be performed by the one or more servers, wherein the specification is defined by the end-user network and comprises logical directives, each directive containing conditions that, if satisfied by the received data, define the operations; and providing, to the one or more servers, the operations.

Abstract: A processor that was manufactured by a manufacturer comprises privileged debug operational circuitry, a debug restriction fuse, a credential store, a credential of the manufacturer in the credential store, and debug control circuitry. The debug restriction fuse is a one-time programmable fuse. The debug control circuitry is to automatically restrict access to the privileged debug operational circuitry, based on the debug restriction fuse. The processor may also include public debug operational circuitry, a prevent-unauthorized-debug (PUD) fuse, and an undo-PUD fuse. When the PUD fuse is set and the undo-PUD fuse is clear, the debug control circuitry may respond to an attempt by a debugger to use the public debug operational circuitry by determining whether the debugger is authorized, disallowing access if the debugger is not authorized, and allowing access if the debugger is authorized. Other embodiments are described and claimed.