Abstract: Techniques are provided for authorizations in a virtual computing infrastructure using a federation token service. The techniques may include receiving a request for a launch plan from a user for launching instances in a plurality of sites, determining object permissions required for actions to be performed to launch one or more of the instances at each site of the plurality of sites, contacting an authorization caching service to obtain authorization tokens for each of the determined object permissions required for the actions, receiving the authorization tokens for each of the determined object permissions required for the actions, and forwarding the request to each site of the plurality of sites with an authentication token and the authorization tokens for each of the determined object permissions required for the actions to be performed to launch the one or more of the instances at each site of the plurality of sites.

Abstract: A method includes using an illumination device to illuminate an object with electromagnetic radiation produced by a radiation source, and using a detector device to capture a respective intensity distribution in a diffraction image produced by the object in a plurality of measurement steps. The measurement steps differ from one another with respect to the illumination setting set by the illumination device. The method also includes determining at least one characteristic variable that is characteristic for the object on the basis of an iteratively performed comparison between the measurement values obtained within the scope of the measurement steps and model-based simulated values. The model-based simulated values are ascertained on the basis of a multiple layer model, in which the object is modeled by a multiple layer structure made of layers that are respectively separated from one another by an interface, wherein a location-dependent reflectivity is assigned to the interfaces.

Abstract: Provided herein are antibodies that bind to the alpha subunit of an IL-7 receptor (IL-7R?). Also provided are uses of these antibodies in therapeutic applications, such as treatment of inflammatory diseases. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain regions of the antibodies, and vectors comprising the polynucleotides.

Abstract: The present invention provides a method of treating a tau-mediated cognitive or neurodegenerative disease, comprising administering to a patient in need of such treatment an effective amount of an anti-Tau antibody and an effective amount of an OGA inhibitor.

Abstract: A method of treating a cognitive or neurodegenerative disease, comprising administering to a patient in need of such treatment an effective amount of an anti-N3pGlu Abeta antibody, an anti-Abeta antibody, or an antibody fragment that binds Amyloid beta and is covalently attached to a polyethylene glycol molecule, in combination with an effective amount of an anti-Tau antibody.

Abstract: Techniques are provided for authorizations in a virtual computing infrastructure using a federation token service. The techniques may include receiving a request for a launch plan from a user for launching instances in a plurality of sites, determining object permissions required for actions to be performed to launch one or more of the instances at each site of the plurality of sites, contacting an authorization caching service to obtain authorization tokens for each of the determined object permissions required for the actions, receiving the authorization tokens for each of the determined object permissions required for the actions, and forwarding the request to each site of the plurality of sites with an authentication token and the authorization tokens for each of the determined object permissions required for the actions to be performed to launch the one or more of the instances at each site of the plurality of sites.

Abstract: A system may include one or more processors disposed within a management network. An end-user network may contain agent instances and one or more servers, where the one or more servers are operable to: (i) receive communications to the end-user network, and (ii) assign agent instances to service the communications. The one or more processors may be configured to perform one or more tasks. These tasks may include receiving, from the end-user network, data associated with the processes of the one or more servers; determining, based on a specification, operations to be performed by the one or more servers, wherein the specification is defined by the end-user network and comprises logical directives, each directive containing conditions that, if satisfied by the received data, define the operations; and providing, to the one or more servers, the operations.

Abstract: Various aspects of upper arm prosthetic system for a human subject having a body and a partial arm are described. According to one aspect, the system may comprise any one or more of a force amplification apparatus, a terminal unit apparatus, and/or an adjustable elbow apparatus. Each apparatus may be body-powered and/or comprise 3D printable structures. Related upper arm prosthetic apparatus, kits, methods, and systems also are described.

Abstract: A predictive maintenance system and method for a dental handpiece includes a condition sensor for sensing a condition of the handpiece to obtain sensor data and providing wired communication of the sensor data and a device identifier from the handpiece to a delivery unit. The system is configured to store sensor data, a device identifier and a time stamp in data logging equipment to obtain a usage history for the handpiece. The system determines a maintenance condition of the handpiece based on the sensor data and/or the usage history of the handpiece. In response to a severity of the maintenance condition, the system provides a preventative maintenance indication of a future failure for the handpiece or stops operation of the handpiece.

Abstract: A handpiece maintenance system and method identifies a dental handpiece and operates in a diagnostic cycle to power the handpiece and determine predictive maintenance condition thereof. The handpiece maintenance system includes a temperature sensor and/or an acceleration sensor to measure the conditions of the handpiece during the diagnostic cycle. The predictive maintenance condition of the handpiece is based on data from the diagnostic cycle and other stored data for the identified handpiece. A system is also configured to determine a predictive maintenance condition of the handpiece based on sensor data read from a handpiece and historical usage data thereof.

Abstract: A bodywork structure for a passenger vehicle includes a bodywork shell construction with two longitudinal girders and a flexible crossmember device attached to the two longitudinal girders. The flexible crossmember device has a first flexible crossmember and two energy absorption elements where the two energy absorption elements are respectively fixed to the two longitudinal girders and the first flexible crossmember is connected to the two longitudinal girders via the two energy absorption elements. A support framework is disposed between the two longitudinal girders and has a second flexible crossmember that is at least indirectly connected to the two longitudinal girders and is convexly curved in a direction of the first flexible crossmember. The support framework has a load divider disposed between the first flexible crossmember and the second flexible crossmember in the longitudinal direction of the passenger vehicle and extending in the transverse direction of the passenger vehicle.

Abstract: A system may include one or more processors disposed within a management network. An end-user network may contain agent instances and one or more servers, where the one or more servers are operable to: (i) receive communications to the end-user network, and (ii) assign agent instances to service the communications. The one or more processors may be configured to perform one or more tasks. These tasks may include receiving, from the end-user network, data associated with the processes of the one or more servers; determining, based on a specification, operations to be performed by the one or more servers, wherein the specification is defined by the end-user network and comprises logical directives, each directive containing conditions that, if satisfied by the received data, define the operations; and providing, to the one or more servers, the operations.

Abstract: A system may include one or more processors disposed within a management network. An end-user network may contain agent instances and one or more servers, where the one or more servers are operable to: (i) receive communications to the end-user network, and (ii) assign agent instances to service the communications. The one or more processors may be configured to perform one or more tasks. These tasks may include receiving, from the end-user network, data associated with the processes of the one or more servers; determining, based on a specification, operations to be performed by the one or more servers, wherein the specification is defined by the end-user network and comprises logical directives, each directive containing conditions that, if satisfied by the received data, define the operations; and providing, to the one or more servers, the operations.

Abstract: A system for magnetic resonance imaging a subject is provided. The system includes a magnet assembly and a controller. The controller is in electronic communication with the magnet assembly and operative to: perform an inversion recovery pulse on the subject via the magnet assembly; acquire an ultrashort echo from the subject via the magnet assembly using a hybrid encoding scheme; and generate an image of the subject based at least in part on the ultrashort echo.

Abstract: The high voltage drive for the transducer of an ultrasonic transducer probe is provided by an active supply that monitors the high voltage supplied to the transducer by means of feedback, and responds to a decline in voltage during high voltage transmission by coupling charge from a capacitor to the high voltage supply line of the probe, thereby preventing a precipitous decline in the high voltage. Preferably the active supply and the capacitor are located in the probe connector enclosure.

Abstract: Generally, a variable fan speed control in an HVAC system is described. Such methods and systems to control fan speed can in turn improve efficiency of the HVAC system by minimizing power consumption, for example of the compressor. The control scheme is based on various operating conditions of compressor load and ambient air temperature, which are used to determine an optimum fan speed.

Abstract: The present invention relates to devices and methods for coating microprojection or microneedle arrays including arrays that contain vaccine formulations, more specifically to multivalent vaccine formulations where components of the multivalent vaccine might be incompatible.

Abstract: A method and system to provide multi-layered access control for healthcare datasets are disclosed. The method comprises defining an information policy for each of healthcare datasets, wherein the information policy comprises information access permissions. Further, an organization policy is defined for each of the healthcare datasets, wherein the organization policy comprises license permissions for organizations accessing the healthcare datasets. Thereafter, a user account master policy is defined for each of the healthcare datasets, wherein the user account master policy comprises account permissions assigned to users of the organizations. Subsequently, a master user policy is generated for each of the users based on the information policy, the organization policy, the user account master policy, or a combination thereof, wherein the master user policy comprises access control permissions to provide each of the users access to the healthcare datasets.

Abstract: Provided herein are antibodies that bind to the alpha subunit of an IL-7 receptor (IL-7R?). Also provided are uses of these antibodies in therapeutic applications, such as treatment of inflammatory diseases. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain regions of the antibodies, and vectors comprising the polynucleotides.