Abstract: A method for qualifying a specimen prepared on one or more hematoxylin and eosin (H&E) slides by assessing an expected yield of nucleic acids for tumor cells and providing associated unstained slides for subsequent nucleic acid analysis is provided.

Abstract: The present invention generally relates to an image guided variable spot stimulation-based electrophysiology assessment device for different biomedical applications. Specifically, the invention relates to application of the device to perform image-guided functional assessment upon variable spot optical stimulation of light-activatable biological specimens to determine changes in the functional health during disease progression and therapy. More specifically, the invention relates to the application of the device in the diagnosis of visual and neurological disorders.

Abstract: Provided are nanonets comprising a) a surfactant aggregate having an average aggregate diameter; and b) a polymer having an average particle diameter which average particle diameter is the same or smaller than the average aggregate diameter, wherein the nanonet has a diameter larger than the average particle diameter. Also provided are kits therefor and methods for sequestering non-water moieties from aqueous solutions using nanonets.

Abstract: Provided are nanonets comprising a) a surfactant aggregate having an average aggregate diameter; and b) a polymer having an average particle diameter which average particle diameter is the same or smaller than the average aggregate diameter, wherein the nanonet has a diameter larger than the average particle diameter. Also provided are kits therefor and methods for sequestering non-water moieties from aqueous solutions using nanonets.

Abstract: Provided are sequestering agents for sequestering non-water moieties from an aqueous solution. The sequestering agents may comprise a detergent; and a polymer operable to stabilize formation of a detergent micelle thereby causing the detergent and polymer to self-assemble into a nanonet upon exposure to the aqueous solution. Also provided are kits therefore and methods for use of the sequestering agents and kits.

Abstract: A method for qualifying a specimen prepared on one or more hematoxylin and eosin (H&E) slides by assessing an expected yield of nucleic acids for tumor cells and providing associated unstained slides for subsequent nucleic acid analysis is provided.

Abstract: Provided are compositions comprising: (a) compound of formula (I): and (b) a compound of formula II: These compositions are NanoNets™ and generally comprise a surfactant of formula (I) and a polymer of formula (II). These NanoNets™ may be used in the treatment of aqueous solutions and more particularly may be used for the removal of boron from aqueous solutions.

Abstract: Autonomous driving systems and methods for a vehicle include a driver intent determination system configured to determine a driver intent for which of two different lanes the driver intends the vehicle to follow during a lane split scenario and a controller configured to operate the vehicle according to an autonomous driving feature whereby the controller automatically controls steering of the vehicle, determine which of the two different lanes are supported for the autonomous driving feature, determine which of the two different lanes that the vehicle will follow during the lane split scenario based at least on the determined driver intent and which of the two different lanes are supported for the autonomous driving feature to obtain a target lane, and automatically control at least the steering system of the vehicle to follow the target lane.

Abstract: A computing system includes a processor; an electronic network; and a memory having stored thereon computer-executable instructions that, when executed, cause the computing system to: process segmented tile images by: (i) predicting a respective biomarker classification, and (ii) predicting a respective tissue classification; determine, based on (i) and (ii), a predicted presence of biomarkers; and transmit the predicted presence. A non-transitory computer-readable medium includes computer-executable instructions that, when executed by a processor, cause a computer to: process segmented tile images by: (i) predicting a respective biomarker classification, and (ii) predicting a respective tissue classification; determine, based on (i) and (ii), a predicted presence of biomarkers; and transmit the predicted presence.

Abstract: There is disclosed vision quantification systems and methods designed to evaluate functional vision. Specifically, the systems are designed with the intent to track a subject's vision using mobility and dexterity assessments. More specifically, at least one aspect of the invention relates to the design and application of the systems in the functional vision assessments in patients with low vision.

Abstract: The present invention generally relates to an image guided variable spot stimulation-based electrophysiology assessment device for different biomedical applications. Specifically, the invention relates to application of the device to perform image-guided functional assessment upon variable spot optical stimulation of light-activatable biological specimens to determine changes in the functional health during disease progression and therapy. More specifically, the invention relates to the application of the device in the diagnosis of visual and neurological disorders.

Abstract: A centrifugal blower is described herein. The centrifugal blower may be a belt-driven geared centrifugal blower. The centrifugal blower may comprise an impeller, an inlet, and an outlet. The impeller pulls air in through the inlet, compresses and speeds up the air, and directs the air out the outlet. A motor may power a pulley system coupled to the belt that, in turn, drives a gear set. The gear set then drives the impeller. A mounting frame for the centrifugal blower may comprise a plurality of mounting holes for increasing the airflow to the gear set for cooling there. A belt tensioner may be coupled to the pulley system for setting a preload in the pulley system. An adjustment system for adjusting the tension provided by the belt tensioner is disclosed.

Abstract: An indoor, stationary, bicycle training device that provides advantages over conventional designs of exercise bicycles is provided. The stationary bicycle may include a tilting/pivoting mechanism to orient the indoor bicycle to simulate descending or climbing. The indoor bicycle may include flexible and resilient frame elements to support the indoor training device to move side-to-side under some riding situations thereby simulating the side-to-side swaying motion of an outdoor bicycle under the same riding situations. The indoor bicycle may include several combinations of frame adjustments to provide configurable dimensions of the indoor bicycle to adjust the frame to properly fit the rider, which may be adjusted based on corresponding dimensions of a user's outdoor bicycle. Still other aspects of the stationary bicycle device may aid in creating an “outdoor” feeling while using the device.

Abstract: A system for identifying biomarkers in a digital image of a Hematoxylin and Eosin-stained slide of a target tissue includes a processor and an electronic network; and a memory having stored thereon computer-executable instructions that, when executed by the one or more processors, cause the computing system to: process segmented tile images determine a predicted biomarker presence; and transmit the predicted presence. A non-transitory computer-readable medium includes a set of computer-executable instructions that, when executed by one or more processors, cause a computer to: process segmented tile images; determine a predicted biomarker presence; and transmit the predicted presence. A computer-implemented method includes processing segmented tile images; determining a predicted biomarker presence; and transmitting the predicted presence.

Abstract: A centrifugal blower is described herein. The centrifugal blower may be a belt-driven geared centrifugal blower. The centrifugal blower may comprise an impeller, an inlet, and an outlet. The impeller pulls air in through the inlet, compresses and speeds up the air, and directs the air out the outlet. A motor may power a pulley system coupled to the belt that, in turn, drives a gear set. The gear set then drives the impeller. A mounting frame for the centrifugal blower may comprise a plurality of mounting holes for increasing the airflow to the gear set for cooling there. A belt tensioner may be coupled to the pulley system for setting a preload in the pulley system. An adjustment system for adjusting the tension provided by the belt tensioner is disclosed.

Abstract: The present invention generally relates to an image-guided laser irradiation device for targeted ablation, stimulation, molecular delivery and therapy. Specifically, the invention relates to application of the device in therapies needing precise and targeted removal of a sample, or delivery of impermeable molecules for therapeutic outcome. More specifically, the invention relates to the application of the device in the therapy of visual disorders.

Abstract: An electrical system for a vehicle includes a main battery system configured to provide power for starting/cranking an engine of the vehicle, an auxiliary battery system configured to provide power for powering a set of accessory loads of the vehicle during starting/cranking of the engine, and a solid-state device disposed therebetween and including a solid-state switch configured to close/open to connect/disconnect the main and auxiliary battery systems to/from each other and intelligence circuity configured to monitor voltages in the main and auxiliary battery systems or current flowing therethrough and, based on the monitoring, commanding the solid-state switch to open to isolate the other of the main and auxiliary battery systems, wherein the isolated one of the main and auxiliary battery systems is configured to provide a degraded but operational operation of an L2+ autonomous driving feature of the vehicle.