Abstract: An indoor, stationary, bicycle training device that provides advantages over conventional designs of exercise bicycles is provided. The stationary bicycle may include a tilting/pivoting mechanism to orient the indoor bicycle to simulate descending or climbing. The indoor bicycle may include flexible and resilient frame elements to support the indoor training device to move side-to-side under some riding situations thereby simulating the side-to-side swaying motion of an outdoor bicycle under the same riding situations. The indoor bicycle may include several combinations of frame adjustments to provide configurable dimensions of the indoor bicycle to adjust the frame to properly fit the rider, which may be adjusted based on corresponding dimensions of a user's outdoor bicycle. Still other aspects of the stationary bicycle device may aid in creating an “outdoor” feeling while using the device.

Abstract: Provided are sequestering agents for sequestering non-water moieties from an aqueous solution. The sequestering agents may comprise a detergent; and a polymer operable to stabilize formation of a detergent micelle thereby causing the detergent and polymer to self-assemble into a nanonet upon exposure to the aqueous solution. Also provided are kits therefore and methods for use of the sequestering agents and kits.

Abstract: A generalizable and interpretable deep learning model for predicting biomarker status and biomarker metrics from histopathology slide images is provided.

Abstract: An indoor, stationary, bicycle training device that provides advantages over conventional designs of exercise bicycles is provided. The stationary bicycle may include a tilting/pivoting mechanism to orient the indoor bicycle to simulate descending or climbing. The indoor bicycle may include flexible and resilient frame elements to support the indoor training device to move side-to-side under some riding situations thereby simulating the side-to-side swaying motion of an outdoor bicycle under the same riding situations. The indoor bicycle may include several combinations of frame adjustments to provide configurable dimensions of the indoor bicycle to adjust the frame to properly fit the rider, which may be adjusted based on corresponding dimensions of a user's outdoor bicycle. Still other aspects of the stationary bicycle device may aid in creating an “outdoor” feeling while using the device.

Abstract: An actuator for imparting steering movement to a tiller of a propulsion unit of a marine vessel comprises an absolute position sensor operable to sense a steering position and a relative position sensor operable to sense a position of the motor. A steering control unit calibrates the relative position sensor based on a signal of the absolute position sensor. Calibration of the relative position sensor based on a signal of the absolute position sensor initializes an accumulative position which accumulates a relative position as the actuator moves over time.

Abstract: Provided are nanonets comprising a) a surfactant aggregate having an average aggregate diameter; and b) a polymer having an average particle diameter which average particle diameter is the same or smaller than the average aggregate diameter, wherein the nanonet has a diameter larger than the average particle diameter. Also provided are kits therefor and methods for sequestering non-water moieties from aqueous solutions using nanonets.

Abstract: A generalizable and interpretable deep learning model for predicting biomarker status and biomarker metrics from histopathology slide images is provided.

Abstract: Provided are sequestering agents for sequestering non-water moieties from an aqueous solution. The sequestering agents may comprise a detergent; and a polymer operable to stabilize formation of a detergent micelle thereby causing the detergent and polymer to self-assemble into a nanonet upon exposure to the aqueous solution. Also provided are kits therefore and methods for use of the sequestering agents and kits.

Abstract: A method for qualifying a specimen prepared on one or more hematoxylin and eosin (H&E) slides by assessing an expected yield of nucleic acids for tumor cells and providing associated unstained slides for subsequent nucleic acid analysis is provided.

Abstract: An electric actuator for a marine steering system comprises a housing and an output shaft reciprocatingly received by the housing. There is a rotor disposed within the housing. The rotor is coupled to the output shaft of the electric actuator. Rotation of the rotor causing the output shaft of the electric actuator to reciprocate relative to the housing. There is a motor disposed within the housing. The motor has an output shaft coupled to the rotor. A longitudinal axis of the output shaft of the motor is parallel with a longitudinal axis of the output shaft of the electric actuator. There is also a drive mechanism disposed within the housing. The drive mechanism couples the output shaft of electric actuator to the rotor. The drive mechanism is on a plane radial to a longitudinal axis of the output shaft of the motor. There is an actuator position sensor disposed on the rotor for sensing a position of the rotor. The actuator position sensor senses an actual steering position based on a position of the rotor.

Abstract: A method for predicting an expected yield of nucleic acid from tumor cells within a dissection boundary on a hematoxylin and eosin (H&E) slide is provided.

Abstract: A method for determining tumor block sufficiency for generating one or more hematoxylin and eosin (H&E) slides by assessing an expected yield of nucleic acids for tumor cells and determining a number of H&E slide for satisfying a desired total nucleic yield is provided.

Abstract: A method for qualifying a specimen prepared on one or more hematoxylin and eosin (H&E) slides by assessing an expected yield of nucleic acids for tumor cells and providing associated unstained slides for subsequent nucleic acid analysis is provided.

Abstract: A generalizable and interpretable deep learning model for predicting biomarker status and biomarker metrics from histopathology slide images is provided.

Abstract: A generalizable and interpretable deep learning model for predicting biomarker status and biomarker metrics from histopathology slide images is provided.

Abstract: Scaffold peptides and methods of making and using same. The scaffold peptides have a general structure from the N-terminus to the C-terminus, AH1-linker-AH2. AH1 and AH2 each comprise an alpha helical structure and may fold against each other about the linker to form a bi-helical structure. The scaffold peptide includes alternating polar and non-polar regions. The non-polar regions of the scaffold peptide interact with the hydrophobic regions of the proteins to solubilize same in aqueous solutions without the presence of detergent. In some embodiments, the scaffold peptides are used for hydrophobic protein purification, isolation and/or stabilization.