Abstract: A method for processor-implemented method includes receiving an integrated circuit (IC) troubleshooting query for an IC. The IC troubleshooting query is received from a user. The method also includes performing natural language processing and machine learning to cluster the IC troubleshooting query into one of a number of semantically similar troubleshooting categories. The method further includes retrieving resolution data from an expert system library, based on a mapping between categories of user solutions and a topic of the IC troubleshooting query. The method also includes generating a recommendation in response to the IC troubleshooting query, based on the resolution data. The method outputs the recommendation to the user.

Abstract: A method for labeling a data set by a coding model includes generating multiple sets of related initial labels based on processing a data set with a group of initial labels. The method also includes determining a quantity of occurrences, within the data set, of each one of the group of initial labels and each related initial label of the multiple sets of related initial labels. The method further includes determining, for each initial label of the group of initial labels, a breadth score based on the number of occurrences of each related initial label. The method still further includes updating one or more of the group of initial labels based on respective breadth scores satisfying a label updating condition. The method also includes labeling the data set based on the group of initial labels and the multiple sets of related initial labels.

Abstract: Methods, systems, and apparatuses that enable a Service Layer (SL) to support analysis of internet of things (IoT) data and enable shared access to information generated by the analysis. An analytics management service may allow SL entities to configure analytics functions for many different IoT sources of data and organize the results in a customizable manner. The SL may support coordinating the analysis of IoT data from multiple independent sources and organizing the results of the analysis.

Abstract: Methods and systems are described for providing conditional access to a service. One or more tasks may be associated with a user profile. The one or more tasks may be indicated as required to be completed to access the service. The one or more tasks may have associated deadlines. If a task is not completed by the deadline, then any device associated with the user profile may be blocked from access to the service.

Abstract: The present invention relates to multimers of polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. The invention also describes the multimerization of polypeptides through various chemical linkers and hinges of various lengths and rigidity using different sites of attachments within polypeptides. In particular, the invention describes multimers of peptides which are high affinity binders of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly the spike protein S1 of SARS-CoV-2. The invention also includes pharmaceutical compositions comprising said polypeptides and to the use of said polypeptides in suppressing or treating a disease or disorder mediated by infection of SARS-CoV-2 or for providing prophylaxis to a subject at risk of infection of SARS-CoV-2.

Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of the COVID-19 nucleocapsid protein (N-protein). The invention also includes pharmaceutical compositions comprising said polypeptides and to the use of said polypeptides in suppressing or treating a disease or disorder mediated by the COVID-19 nucleocapsid protein (N-protein), such as infection of COVID-19 or for providing prophylaxis to a subject at risk of infection of COVID-19.

Abstract: An integrated multi-layered lighting system includes a first board having a first component area and a first light area, a second board coupled to and offset from the first board, the second board having a first opening overlapping the first light area of the first board in a plan view, and a second component area overlapping the first component area of the first board in a plan view, a plurality of light emitting diodes (LEDs) coupled to the first board and positioned in the first light area corresponding to the first opening of the second board, and a light driver configured to drive the plurality of LEDs and including a plurality of first components coupled to the first board and positioned in the first component area and a plurality of second components coupled to the second board and positioned in the second component area.

Abstract: Methods, system, and apparatuses may support end-to-end (E2E) quality of service (QoS) through the use of service layer (SL) sessions. For example, an application can communicate with a targeted device based on application specified schedule, latency, jitter, error rate, throughput, level of security, and cost requirements.

Abstract: Methods and devices to capture and analyze aerosolized particles in exhaled air including protein biomarkers and their truncated proteoforms characteristic of tuberculosis to enable rapid detection of diseases. Methods and systems to selectively capture aerosolized particles using a packed bed column. The captured particles are eluted using one or more solvents and analyzed using devices including MALDI-TOFMS.

Abstract: Provided are organometallic compounds comprising a chelating tetradentate ligand with at least four cyclic structures located around a central Pt or Pd atom that can be used as light-emitters. Also provided are formulations comprising these organometallic compounds. Further provided are organic light emitting devices (OLEDs) and related consumer products that utilize these organometallic compounds.

Abstract: The present disclosure relates to bifunctional compounds, which find utility as modulators of SMARCA2 or BRM (target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a ligand that binds to the Von Hippel-Lindau E3 ubiquitin ligase, and on the other end a moiety which binds the target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

Abstract: Techniques are generally described for fusing sensor data of different modalities using a transformer. In various examples, first sensor data may be received from a first sensor and second sensor data may be received from a second sensor. A first feature representation of the first sensor data may be generated using a first machine learning model and a second feature representation of the second sensor data may be generated using a second machine learning model. In some examples, a modified first feature representation of the first sensor data may be generated based at least in part on a self-attention mechanism of a transformer encoder. The modified first feature representation may be generated based at least in part on the first feature representation and the second feature representation. A computer vision task may be performed using the modified first feature representation.

Abstract: The present invention provides a compound having the structure: wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R4 is H, OH, or halogen; B is a substituted or unsubstituted heterobicycle, pyridazine, pyrazole, pyrazine, thiadiazole, or triazole, wherein the heterobicycle is other than chloro substituted indole; and the pyrazole, when substituted, is substituted with other than trifluoromethyl, or a pharmaceutically acceptable salt thereof.

Abstract: A light driver includes a pulse generator circuit configured to generate a pulsed signal based on a rectified input line voltage, a dimming detection circuit configured to determine whether phase-cut dimming is present at an input of the light driver based on the pulsed signal and to generate a phase-cut detection signal, and an input selection circuit configured to apply a first voltage or a second voltage to a reference input of a power factor correction (PFC) circuit of the light driver based on the phase-cut detection signal.

Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that specifically bind and inhibit TREM-1 signaling, wherein the antibodies do not bind to one or more Fc?Rs and do not induce the myeloid cells to produce inflammatory cytokines. Also provided are uses of such antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of autoimmune diseases.

Abstract: Systems, devices, media, and methods are presented for releasing an application feature in incremental stages while monitoring the application for anomalies. The feature includes a package of code and an action setting. The methods in some implementations include identifying active devices on which the application has been installed, monitoring the application according to a set of metrics, activating the feature by changing its action setting for a first segment of the active devices, pausing the feature if an anomaly is detected among the set of metrics, and generating a repair ticket. As long as no anomaly is detected, the activating step proceeds for subsequent segments of the active devices, iteratively, until the release is completed. A feature rank may be used to process and release a plurality of features in order of priority.

Abstract: Methods of forming interconnects and electronic devices are described. Methods of forming interconnects include forming a tantalum nitride layer on a substrate; forming a ruthenium layer on the tantalum nitride layer; and exposing the tantalum nitride layer and ruthenium layer to a plasma comprising a mixture of hydrogen (H2) and argon (Ar) to form a tantalum doped ruthenium layer thereon. Apparatuses for performing the methods are also described.

Abstract: An online concierge system allows users to order items within discrete time intervals later than a time when an order was received or for short-term fulfillment when the order was received. To account for a number of shoppers available to fulfill orders during different discrete time intervals and numbers of orders for fulfillment during different discrete time intervals, the online concierge system specifies a target rate for orders fulfilled later than a specified discrete time interval and a threshold from the target rate. A trained machine learning model periodically predicts a percentage of orders being fulfilled late, with an order associated with a predicted percentage when the order was received. The online concierge system increases a price of orders associated with predicted percentages greater than the threshold from the target rate. The increased price of an order is determined from a price elasticity curve and the predicted percentage.

Abstract: Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.

Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of Nectin-4. The invention also includes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups, to pharmaceutical compositions comprising said peptide ligands and drug conjugates and to the use of said peptide ligands and drug conjugates in preventing, suppressing or treating a disease or disorder mediated by Nectin-4.