Abstract: An indicator assembly according to certain embodiments generally includes a mounting bracket, a follower, a transmission ring, and an indicator plate. The follower is rotatably mounted to the mounting bracket, and is configured to receive a tailpiece of an input device. The transmission ring is rotatably mounted to the mounting bracket, and is engaged with the follower. The indicator plate is slidably mounted to the mounting bracket for movement between a first indicator plate position and a second indicator plate position to selectively place a first indicium of the indicator plate within a reference area. The transmission ring is operably connected with the indicator plate such that movement of the transmission ring between a first transmission ring position and a second transmission ring position drives the indicator plate between the first indicator plate position and the second indicator plate position.

Abstract: Systems and methods automate the design and execution of randomized experiments. Portions of a field are planted using an agricultural vehicle configured to randomly vary planting parameters when planting a portion of the field. A resulting crop outcome across each portion or sub-portion of the field is observed. A training set of data is generated that includes the varied planting parameters and the associated crop outcomes for each portion of the field. A machine-learned model is trained using the training set of data and is configured to predict a crop outcome for a portion of the field based on historical and forecast conditions and a set of planting parameters applied to a portion of the field. For subsequent iterations, for a target portion of the field, the machine-learned model can be applied to identify a set of planting parameters for planting the target portion of the field to optimize a desired crop outcome.

Abstract: A smart valve gas shut-off system for use in a building to detect the presence of natural gas and to shut off the supply of gas leading to the appliance from where the gas was detected. The smart valve gas shut-off system uses a sensor to detect the natural gas and a sensor alarm, in the form of a light indicator or other indicator, that while the sensor is in the alarm state, the valve controlling the supply of gas to the appliance is disabled as well as the reset button, meaning the valve that controls the flow of gas cannot be opened.

Abstract: A portable pump is provided for negative pressure wound therapy for drawing a vacuum from a wound site via a tube. The pump includes an inlet configured to attach the tube from the wound site; a canister in fluid communication with the inlet for collecting fluids drained from the wound site; and a manually-actuated pump mechanism for creating the vacuum. The pump mechanism includes a vacuum chamber in fluid communication with the canister; a piston disposed in the vacuum chamber; and a pump handle coupled to the piston to move the piston in the vacuum chamber between first and second positions to create the vacuum. The pump handle moving between a retracted position and an extended position. The piston is in the first position when said pump handle is in the retracted position and is in the second position when said pump handle is in the extended position.

Abstract: Compositions and methods are disclosed for targeting the clustered protocadherins for therapeutic effect. More specifically, compositions and methods are disclosed to modify select isoforms in the ?, ?, and ? cluster to promote tissue regeneration or to target and reduce tumor burden in diverse cancer types. The methods have application in veterinary and human medicine.

Abstract: In one aspect, the disclosure relates to the use of poly(diethylenepolyamine) derivatives for the extraction of metals, in particular rare-earth metals. In another aspect the disclosure relates to articles and methods for extracting rare-earth metals.

Abstract: A method and computer-readable recording media using a self-describing module for updating data in a medical monitoring device. The self-describing module includes a metadata block (MDB) that includes at least identification (ID) data and corresponding configuration data. The medical monitoring device includes a plurality of sub-systems. Associating ID data from the MDB with ID data of the plurality of sub-systems of the medical monitoring device, and then updating configuration data of at least one sub-system with the configuration data in the MDB based on the result of the association.

Abstract: The present disclosure concerns Bcl-xL inhibitors having low cell permeability, antibody drug conjugates (ADCs) comprising the inhibitors, synthons useful for synthesizing the ADCs, compositions comprising the inhibitors or ADCs, and various methods of using the inhibitors and ADCs.

Abstract: A stent delivery system including an elongate shaft of a medical device, a stent selectively coupled to a distal portion of the elongate shaft, and a coupling mechanism for selectively coupling the stent to the elongate shaft by inserting a tab on one of the stent or the elongate shaft into an opening in the other of the stent or the elongate shaft. The tab may be deflected from a first position to a second position to disengage the tab from the opening.

Abstract: An internal component and external interface arrangement for a cylindrical compact computing system is described that includes at least a structural heat sink having triangular shape disposed within a cylindrical volume defined by a cylindrical housing. A computing engine having a generally triangular shape is described having internal components that include a graphics processing unit (GPU) board, a central processing unit (CPU) board, an input/output (V/O) interface board, an interconnect board, and a power supply unit (PSU).

Abstract: A graphical user interface (GUI) for designing and monitoring an industrial automation system presents an alert based on a condition of an object corresponding to a respective industrial automation device displayed on the GUI. The GUI generates one or more suggestions for resolving the alert, including referencing a historical data set, parsing the historical data set to identify one or more previous instances in which the condition of the object occurred and was successfully resolved, and identifying one or more respective remedial actions taken in each of the one or more identified previous instances to resolve the condition. The GUI presents the one or more remedial actions as the one or more suggestions for resolving the alert, receives an input selecting one of the one or more remedial actions, and implements the selected remedial action.

Abstract: A method of treating non-petroleum or renewable feedstock containing lignins is carried out by introducing a lignin-containing feedstock into a reactor at a flow velocity of from 20 ft/sec to 100 ft/sec. The feedstock is heated within the reactor to a temperature of from 700° F. to 1100 OF to convert the lignin-containing feedstock into a reactor product. The reactor product is cooled to form a cooled reactor product. At least one of gases, metals, and water are separated and removed from the cooled reactor product to form a final product. The final product has a lignin content that is reduced by 10% to 100% by weight of the initial lignin incorporated into the feedstock.

Abstract: A method includes identifying at least one excursion corresponding to sensor data obtained from a manufacturing system, initiating an excursion screening process to screen the at least one excursion using an excursion screening model, wherein the excursion screening model is trained to classify the at least one excursion, and causing a screening output resulting from the screening process to be displayed on a user device.

Abstract: A method of encouraging a user to increase their wager on a play by play wagering platform by determining the likelihood the user will increase their wager based upon their wager history and proposing an increase amount based upon their likelihood of increasing their wager such that a higher likelihood of increase results in a higher proposed increase amount and a lower likelihood results in a lower proposed increase amount.

Abstract: A content access device and system may allow portable remote devices to be paired with a variety of different devices, allowing remote control through a network connection. Content access devices may expose application program interfaces, allowing incoming network traffic to control operation of the device much in the same way that a local infrared remote would. Routing content commands through an external application server may also yield other benefits, such as allowing more customized selection of information and advertising content to users based on their viewing history.

Abstract: Disclosed is a system for qualifying medical images submitted by user for diagnostic analysis comprising: an image input module, configured to receive one or more image input by a user; an image protocol conformation module, configured to receive the one or more images from the image input module, and further configured to analyze each of the one or more images for conformity with a predefined protocol and wherein images that do not conform to the predefined protocol are flagged as non-conforming images; an image output module, configured to identify to the user each of the one or more images flagged as non-conforming and prompting the user to resubmit a new image for each of the non-conforming images; and an image resubmission module, configured to receive the user resubmitted image and provide the resubmitted image to the image protocol conformation module.

Abstract: Haptic feedback from a robotic surgical tool can be adjusted based on intra-operative assessment of the accuracy of a pre-operative surgical navigational plans. Navigational reference points are identified in at least one pre-operative image. At least one haptic response is identified for interactions between at least one robotic surgical tool and at least one navigational reference point. At least one intra-operative image is compared to the pre-operative image to determine the relative position of at least two corresponding navigational reference points in the images. The reference points' relative position determines a confidence level in the accuracy of the pre-operative navigational reference point. The haptic response is adjusted in timing, location, type, or amplitude based upon the confidence level. Tolerances and surgical navigation plan may also be updated and altered based on the confidence level.

Abstract: Methods, system, and kits are provided for sample identification, and, more specifically, for designing, and/or making, and/or using sample discriminating codes or barcodes for identifying sample nucleic acids or other biomolecules or polymers. For example, a plurality of flowspace codewords may be generated, the codewords comprising a string of characters. A location for at least one padding character within the flowspace codewords may be determined. The padding character may be inserted into the flowspace codewords at the determined location. After the inserting, a plurality of the flowspace codewords may be selected based on satisfying a predetermined minimum distance criteria, wherein the selected codewords correspond to valid base space sequences according to a predetermined flow order. And the barcode sequences corresponding to the selected codewords may be manufactured.

Abstract: Provided are systems and methods that allow for brightfield imaging in a flow cytometer, allowing for collection of fluorescence and high-quality image date. The disclosed technology also gives rise to an illumination pattern that allows a user to create different oblique or structured illumination profiles within a static system. With the disclosed approach, a user can illuminate a sample from a first direction (e.g., with laser illumination configured to give rise to one or more of fluorescence information and scattering information), collect scattering information from a second direction, collect fluorescence information from a third direction, and capture an image of the sample from a fourth direction. (Two or more of the foregoing can be accomplished simultaneously.) Also as described elsewhere herein, an illumination used to illuminate the sample for visual image capture can be communicated to the same through a lens that also collects fluorescence from the sample.