Abstract: A system for providing pressurized hydraulic fluid in a transmission of a motor vehicle includes a pump for providing pressurized hydraulic fluid having an inlet port and an outlet port. A bypass valve includes an inlet port in communication with the outlet port of the pump, a first outlet port in communication with the inlet port of the pump, and a second outlet port. The inlet port of the bypass valve is in communication with the second outlet port of the bypass valve when the bypass valve is in a first position and the inlet port of the bypass valve is in communication with the first outlet port of the bypass valve when the bypass valve is in a second position. A control device and accumulator are operatively associated with the bypass valve.

Abstract: A hydraulic control system for a dual clutch transmission includes a source of pressurized hydraulic fluid, first and second actuator control devices in downstream fluid communication with the source of pressurized hydraulic fluid, and first and second clutch control devices in downstream fluid communication with the source of pressurized hydraulic fluid. A first valve is in downstream fluid communication with the first and second actuator control devices. A second valve is in downstream fluid communication with the first valve, the first clutch control device and the second clutch control device, and the second valve is moveable between two positions by the first and second clutch control devices. Selective activation of combinations of the control devices allows for a pressurized fluid to engage the dual clutch and an actuator in order to shift the transmission into a desired gear ratio.

Abstract: A high efficiency hydraulic control system for a dual clutch transmission includes one or two hydraulic pumps. In a first embodiment, a single hydraulic pump provides pressurized hydraulic fluid to a pressure control valve, filter and accumulator. A first pair of variable feed solenoid valves independently and mutually exclusively provide hydraulic fluid to a respective pair of main or input clutch actuators. A second pair of variable feed solenoid valves provide hydraulic fluid to a pair of inlet ports of a first spool or logic valve. The position of the spool of the first logic valve is controlled by an on-off solenoid valve. A first pair of outlet ports of the first logic valve selectively provide hydraulic fluid to a first three area piston which selects two gear or speed ratios, for example, reverse and third gear. A second pair of outlet ports of the first logic valve selectively provide hydraulic fluid to a pair of inlet ports of a second spool or logic valve.

Abstract: A hydraulic fluid circuit for a power transmission device includes a first hydraulic circuit segment fluidly decoupled from a second hydraulic circuit segment. A hydraulic pump includes a first fluidic pumping element and a second fluidic pumping element. The first fluidic pumping element fluidly communicates with the first hydraulic circuit segment. The second fluidic pumping element fluidly communicates with the second hydraulic circuit segment. The first fluidic pumping element is controllable to a first pump operating point to achieve a preferred high fluidic flow rate in the first hydraulic circuit segment. The second fluidic pumping element is controllable to a second pump operating point to achieve a preferred high fluidic pressure in the second hydraulic circuit segment.

Abstract: A hydraulic control system for a transmission includes a motor, a sump for storing a hydraulic fluid, and a dual element pump connected to the motor. The dual element pump has at least one input port connected to the sump, a first outlet port, and a second outlet port. The dual element pump provides a first volume of hydraulic fluid to the first outlet port and provides a second volume of hydraulic fluid to the second outlet port. The first volume is greater than the second volume. The first outlet port is connected to a diversion valve. The second outlet port is connected to a high pressure hydraulic circuit. The diversion valve is operable to transmit the hydraulic fluid from the first outlet port to a low pressure hydraulic circuit and the high pressure hydraulic circuit.

Abstract: The present invention is directed to immune adjuvants containing IAP inhibitors, including Smac mimetics. The invention further provides pharmaceutical compositions and vaccines containing an IAP inhibitor and an antigen. Methods of enhancing an immune response by administration of an IAP inhibitor, methods of treating or preventing cancer, methods of treating or preventing infections, methods of treating autoimmune disorders, and methods of potentiating cytokine or antibody production are also provided.

Abstract: A torque transmitting assembly includes an actuator for engaging a torque transmitting element. A mechanism is connected to the actuator. The mechanism is operable to selectively allow fluid communication therethrough. The mechanism communicates between two separate fluid spaces located on opposite sides of the actuator. During movement of the actuator, a fluid is allowed to transfer through the mechanism between the two separate fluid spaces.

Abstract: The present invention provides a control system for a dual clutch automatic transmission having a torque converter. The transmission provides seven forward speeds or gear ratios and reverse. The control system includes a hydraulic pump, a pressure regulator assembly and control valves that provide and release pressurized hydraulic fluid to the torque converter, a pair of input clutches and eight synchronizer clutches. A first pair of control valves are high flow rate valves which are capable of rapidly engaging and disengaging the input clutches. A second pair of high flow rate valves, control valves and spool valves provide a branching control circuit which controls engagement and disengagement of the synchronizer clutches. A control valve linked to the shift lever blocks hydraulic fluid flow to the first pair of high flow rate valves to inhibit input clutch activation when the shift lever is in Park or Neutral.

Abstract: A torque transmitting assembly includes an actuator for engaging a torque transmitting element. A mechanism is connected to the actuator. The mechanism is operable to selectively allow fluid communication therethrough. The mechanism communicates between two separate fluid spaces located on opposite sides of the actuator. During movement of the actuator, a fluid is allowed to transfer through the mechanism between the two separate fluid spaces.

Abstract: A dental floss device includes a handle having a head piece and a disposable holder for a length of dental floss. The holder includes a base portion and a pair of spaced-apart jaws extending from the base and which extend to embrace the head piece of the handle when the holder is in a correct alignment configuration with respect to the handle. The device has an interlock which ensures that the holder can be interengaged with the head piece only when the holder is correctly aligned with the head piece. The interlock includes a head interlock part provided by interlock grooves and a holder interlock part provided by corresponding interlock tongues. There are two interlock grooves and corresponding interlock tongues which slidably interengage when the holder is correctly aligned with the head piece If the holder is turned so that it is not correctly aligned with the head piece, the interlock tongues of the holder prevent engagement of the holder with the head piece.

Abstract: A dental floss device 1 comprises a handle 2 having a head piece 3 and a disposable holder 4 for a length of dental floss 5. The holder 4 comprises a base portion 20 and a pair of spaced-apart jaws 21 extending from the base and which extend to embrace the head piece 3 of the handle 2 when the holder 4 is in a correct alignment configuration with respect to the handle 2. The device has an interlock which ensures that the holder 4 can be interengaged with the head piece 3 only when the holder 4 is correctly aligned with the head piece 3. The interlock comprises a head interlock part provided by interlock grooves 10 and a holder interlock part provided by corresponding interlock tongues 11. There are two interlock grooves 10 and corresponding interlock tongues 11 which slidably interengage when the holder 4 is correctly aligned with the head piece 3.

Abstract: A dental floss device includes a handle having a head piece and a disposable holder for a length of dental floss. The holder includes a base portion and a pair of spaced-apart jaws extending from the base and which extend to embrace the head piece of the handle when the holder is in a correct alignment configuration with respect to the handle. The device has an interlock which ensures that the holder can be interengaged with the head piece only when the holder is correctly aligned with the head piece. The interlock includes a head interlock part provided by interlock grooves and a holder interlock part provided by corresponding interlock tongues. There are two interlock grooves and corresponding interlock tongues which slidably interengage when the holder is correctly aligned with the head piece. If the holder is turned so that it is not correctly aligned with the head piece, the interlock tongues of the holder prevent engagement of the holder with the head piece.

Abstract: An electric motor driven pump has a regulator valve for establishing a system pressure within a predetermined pressure range. The regulator valve has three bias pressures and a spring force imposed thereon. One of the bias pressures assists the spring to increase the system pressure and the other two bias pressures either balance the spring and one bias pressure or lower the system pressure. The one bias pressure is established by an electro-hydraulic control mechanism as a function of operating parameters in a powertrain which uses the fluid pressure from the pump. One of the other bias pressures is equal to system pressure and the last bias pressure is available when a predetermined drive condition is requested in the powertrain. A first electrical switch is activated by fluid pressure from the regulator valve if the system pressure is below the demanded pressure and a second electrical switch is activated by fluid pressure from the regulator valve if the system pressure is above the demanded pressure.

Abstract: A dental floss device 1 comprises a handle 2 having a head piece 3 and a disposable holder 4 for a length of dental floss 5. The holder 4 comprises a base portion 20 and a pair of spaced-apart jaws 21 extending from the base and which extend to embrace the head piece 3 of the handle 2 when the holder 4 is in a correct alignment configuration with respect to the handle 2. The device has an interlock which ensures that the holder 4 can be interengaged with the head piece 3 only when the holder 4 is correctly aligned with the head piece 3. The interlock comprises a head interlock part provided by interlock grooves 10 and a holder interlock part provided by corresponding interlock tongues 11. There are two interlock grooves 10 and corresponding interlock tongues 11 which slidably interengage when the holder 4 is correctly aligned with the head piece 3.