Patents by Inventor Michael Dwyer

Michael Dwyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240090499
    Abstract: Described herein is a preservative composition, which includes polylysine, and a medium chain fatty acid (C6-C14) or a 1-monoglyceride derivative thereof. The preservative composition is able to confer both bacterial resistance and fungal resistance without substantially including non-naturally derived products. Also described are methods of improving microbial resistance in food, beverage, cosmetic products and/or pharmaceutical products, and cosmetic compositions including the preservative composition described herein.
    Type: Application
    Filed: September 15, 2023
    Publication date: March 21, 2024
    Inventors: Tianxiang Wang, Paul Stettnisch, Rosa Dwyer, Michael Ingrassia
  • Publication number: 20240074785
    Abstract: A handle apparatus comprising void regions or attachment devices that accommodate the shape of surgical devices and imaging units such that the device is held securely and mechanically fixed to the imaging unit within the handle assembly.
    Type: Application
    Filed: November 3, 2023
    Publication date: March 7, 2024
    Inventors: Nabil Dib, Brad Knight, Charmaine Dwyer, Michael Nagel, Lowry Barfield
  • Patent number: 11339721
    Abstract: A system and method for supplying compressed air from an auxiliary power unit to a main engine starter motor. The inlet guide vanes are controlled using either first or second inlet guide vane control logic and the surge control valve is controlled using either first or second surge control valve control logic. When the first inlet guide vane control logic is used, the inlet guide vanes are positioned based on a demand signal, when the second inlet guide vane control logic is used, the inlet guide vanes are positioned based on a demand schedule, when the first surge control valve logic is used, the surge control valve can be commanded to repeatedly move to only a fully-closed position and a fully-open position, and when the second surge control valve logic is used, the surge control valve can be commanded to the fully-closed position only when maximum flow is commanded.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: May 24, 2022
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Harold Riley, Michael Dwyer
  • Publication number: 20200149476
    Abstract: A system and method for supplying compressed air from an auxiliary power unit to a main engine starter motor. The inlet guide vanes are controlled using either first or second inlet guide vane control logic and the surge control valve is controlled using either first or second surge control valve control logic. When the first inlet guide vane control logic is used, the inlet guide vanes are positioned based on a demand signal, when the second inlet guide vane control logic is used, the inlet guide vanes are positioned based on a demand schedule, when the first surge control valve logic is used, the surge control valve can be commanded to repeatedly move to only a fully-closed position and a fully-open position, and when the second surge control valve logic is used, the surge control valve can be commanded to the fully-closed position only when maximum flow is commanded.
    Type: Application
    Filed: November 14, 2018
    Publication date: May 14, 2020
    Applicant: HONEYWELL INTERNATIONAL INC.
    Inventors: Harold Riley, Michael Dwyer
  • Patent number: 10646494
    Abstract: The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A?, R2 R3 and R5 are as defined herein. The present invention also relates to compositions comprising at least one Heterocycle-Substituted Tetracyclic Compound, and methods of using the Heterocycle-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: May 12, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Wensheng Yu, Ling Tong, Joseph A. Kozlowski, Craig A. Coburn, De-Yi Yang, Deyou Sha, Jae-Hun Kim, Michael Dwyer, Kartik M Keertikar, Bin Hu, Bin Zhong, Jinglai Hao, Dahai Wang
  • Publication number: 20190175602
    Abstract: The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A?, R2 R3 and R5 are as defined herein. The present invention also relates to compositions comprising at least one Heterocycle-Substituted Tetra-cyclic Compound, and methods of using the Heterocycle-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.
    Type: Application
    Filed: August 14, 2017
    Publication date: June 13, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Wensheng Yu, LING Tong, Joseph A. Koziowski, Craig: A Coburn, De-yi J. Yang, Deyou Sha, Jae-Hun. Kim, Michael Dwyer, Kartik M. Keertikar, Bin Hu, Bin Zhong, Jinglai Hao, Dahai Wang
  • Patent number: 9567906
    Abstract: An aircraft engine system includes a main engine having a main engine speed; a starter coupled to the main engine and configured to drive the main engine with compressed air; and an auxiliary power unit (APU) system coupled to the starter and configured to provide the compressed air to the starter. The APU system includes an APU with a compressor to generate the compressed air, and an APU electronic control unit (ECU) coupled to the APU, the APU ECU configured to receive the engine speed of the main engine and to control operation of the APU to modify an amount of the compressed air to the starter based on the main engine speed.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: February 14, 2017
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Thomas Nesdill, Michael Dwyer, John Arenare, Cecilia Lam
  • Publication number: 20160257697
    Abstract: Thiophene-substituted tetracyclic compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein A, A?, R2, R3, R4 and R5 are as defined herein. The compositions comprising at least one thiophene-substituted tetracyclic compound, and methods of using the thiophene-substituted tetracyclic compounds for treating or preventing HCV infection in a patient are also provided.
    Type: Application
    Filed: December 31, 2013
    Publication date: September 8, 2016
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Ling Tong, Wensheng Yu, Joseph A. Kozlowski, Lei Chen, Oleg Selyutin, Seong Heon Kim, Michael Dwyer, Bin Hu, Bin Zhong, Dahai Wang, Jinglai Hao, Changmao Shen, Zhixin Lei, Weijun Wang
  • Publication number: 20150167553
    Abstract: An aircraft engine system includes a main engine having a main engine speed; a starter coupled to the main engine and configured to drive the main engine with compressed air; and an auxiliary power unit (APU) system coupled to the starter and configured to provide the compressed air to the starter. The APU system includes an APU with a compressor to generate the compressed air, and an APU electronic control unit (ECU) coupled to the APU, the APU ECU configured to receive the engine speed of the main engine and to control operation of the APU to modify an amount of the compressed air to the starter based on the main engine speed.
    Type: Application
    Filed: December 13, 2013
    Publication date: June 18, 2015
    Inventors: Thomas Nesdill, Michael Dwyer, John Arenare, Cecilia Lam
  • Patent number: 8987242
    Abstract: The present invention provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: March 24, 2015
    Assignees: Merck Sharp & Dohme Corp., Mochida Pharmaceuticals Co., Ltd.
    Inventors: Samuel Chackalamannil, Tin-Yau Chan, Mariappan V. Chelliah, Martin C. Clasby, Michael Dwyer, William J. Greenlee, Tomokazu Hirabayashi, Santhosh Neelamkavil, Hidemitsu Nishida, Fumihiko Saitoh, Unmesh Shah, Yan Xia
  • Patent number: 8642582
    Abstract: The present invention provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
    Type: Grant
    Filed: December 3, 2009
    Date of Patent: February 4, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Hidemitsu Nishida, Fumihiko Saitoh, Tomokazu Hirabayashi, Samuel Chackalamannil, Tin-Yau Chan, Mariappan V. Chelliah, Martin C. Clasby, Michael Dwyer, William J. Greenlee, Yan Xia
  • Patent number: 8609676
    Abstract: The present invention relates to novel heterocyclic compounds of Formulae (I): (Chemical formula should be inserted here as it appears on abstract in paper form) Formula (I) as disclosed herein, or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are pharmaceutical compositions comprising said compounds, and methods for using said compounds for treating or preventing a thromboembolic disorder.
    Type: Grant
    Filed: August 3, 2010
    Date of Patent: December 17, 2013
    Assignee: Merck Sharp & Dohme, Corp.
    Inventors: Mariappan V. Chelliah, Samuel Chackalamannil, William J. Greenlee, Keith Eagan, Zhuyan Guo, Martin C. Clasby, Yan Xia, Charles L. Jayne, Michael Dwyer, Kartik M. Keertikar, Tin-Yau Chan, Li Wang
  • Publication number: 20120136016
    Abstract: The present invention relates to novel heterocyclic compounds of Formulae (I): (Chemical formula should be inserted here as it appears on abstract in paper form) Formula (I) as disclosed herein, or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are pharmaceutical compositions comprising said compounds, and methods for using said compounds for treating or preventing a thromboembolic disorder.
    Type: Application
    Filed: August 3, 2010
    Publication date: May 31, 2012
    Inventors: Mariappan V. Chelliah, Samuel Chackalamannil, William J. Greenlee, Keith Eagen, Zhuyan Guo, Martin C. Clasby, Yan Xia, Charles L. Jayne, Michael Dwyer, Kartick M. Keertikar, Tin-Yau Chan, Li Wang
  • Publication number: 20110213029
    Abstract: There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
    Type: Application
    Filed: May 6, 2011
    Publication date: September 1, 2011
    Applicants: Schering Corporation, Pharmacopeia Drug Discovery
    Inventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jianhua Chao, Younong Yu, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Purakkattle J. Biju, Kingsley H. Nelson, JR., Laura L. Rokosz, Gaifa Lai, James P. Jakway, Minglang Wu, Evan A. Hecker, Daniel Lundell, Jay S. Fine
  • Patent number: 7964646
    Abstract: There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
    Type: Grant
    Filed: August 8, 2006
    Date of Patent: June 21, 2011
    Assignees: Schering Corporation, Pharmacopeia Drug Discovery
    Inventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jianhua Chao, Younong Yu, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Purakkattle J. Biju, Kingsley H. Nelson, Jr., Laura L. Rokosz, Gaifa Lai
  • Publication number: 20110135650
    Abstract: The present invention provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
    Type: Application
    Filed: June 1, 2010
    Publication date: June 9, 2011
    Inventors: Samuel CHACKALAMANNIL, Tin-Yau CHAN, Mariappan V. CHELLIAH, Martin C. CLASBY, Michael DWYER, William J. GREENLEE, Tomokazu HIRABAYASHI, Santhosh NEELAMKAVIL, Hidemitsu NISHIDA, Fumihiko SAITOH, Unmesh SHAH, Yan XIA
  • Patent number: 7947720
    Abstract: There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
    Type: Grant
    Filed: January 13, 2009
    Date of Patent: May 24, 2011
    Assignees: Schering Corporation, Pharmacopeia Drug Discovery
    Inventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jianhua Chao, Younong Yu, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Purakkattle J. Biju, Kingsley H. Nelson, Jr., Laura L. Rokosz
  • Publication number: 20110059958
    Abstract: The present invention provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
    Type: Application
    Filed: December 3, 2009
    Publication date: March 10, 2011
    Inventors: Hidemitsu Nishida, Fumihiko Saitoh, Tomokazu Hirabayashi, Samuel Chackalamannil, Tin-Yau Chan, Mariappan V. Chelliah, Martin C. Clasby, Michael Dwyer, William J. Greenlee, Yan Xia
  • Patent number: 7765386
    Abstract: An embodiment of the present invention is a technique to perform floating-point operations for vector processing. An input queue captures a plurality of vector inputs. A scheduler dispatches the vector inputs. A plurality of floating-point (FP) pipelines generates FP results from operating on scalar components of the vector inputs dispatched from the scheduler. An arbiter and assembly unit arbitrates use of output section and assembles the FP results to write to the output section.
    Type: Grant
    Filed: September 28, 2005
    Date of Patent: July 27, 2010
    Assignee: Intel Corporation
    Inventors: David D. Donofrio, Michael Dwyer
  • Publication number: 20100009736
    Abstract: A word game and method of playing the word game comprising providing a main word or phrase (“Theme Word”), and a group of existing words (“Puzzle Words”), wherein each letter from the Theme Word is used once to form a different word (“Solved Word”) when added to a Puzzle Word. In an embodiment, multiple letters from the Theme Word may be added to a single Puzzle Word to form a single Solved Word. The letters from the Theme Word may be added anywhere to the Puzzle Word in order to form a new Solved Word. In an embodiment, the order of the letters in Puzzle Word may not be changed. In another embodiment the letter from the Theme Word may not be added to the end of the Puzzle Word. The game will be considered solved when all of the letters of the Theme Word have been successfully combined once with a Puzzle Word such that each letter has been used with a Puzzle Word to form a Solved Word.
    Type: Application
    Filed: July 10, 2008
    Publication date: January 14, 2010
    Inventor: Michael Dwyer