Patents by Inventor Michael E. Smith
Michael E. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11965029Abstract: Described herein are compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies. In particular embodiments, the disclosure provides fully human anti-ST2 antibodies and deriviatives and variants thereof. Further provided are nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives. Also, provided are methods of making and using such antibodies including methods of treating and preventing autoimmune and inflammatory disorders.Type: GrantFiled: June 4, 2021Date of Patent: April 23, 2024Assignee: Amgen Inc.Inventors: Dirk E. Smith, Ian Foltz, Chadwick T. King, Ai Ching Lim, Rutilio Clark, Michael R. Comeau, Randal R. Ketchem, Donghui Shi, Xiaoshan Min, Zhulun Wang
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Patent number: 11957893Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.Type: GrantFiled: August 25, 2020Date of Patent: April 16, 2024Assignee: Medtronic, Inc.Inventors: Brad C. Tischendorf, John E. Kast, Thomas P. Miltich, Gordon O. Munns, Randy S. Roles, Craig L. Schmidt, Joseph J. Viavattine, Christian S. Nielsen, Prabhakar A. Tamirisa, Anthony M. Chasensky, Markus W. Reiterer, Chris J. Paidosh, Reginald D. Robinson, Bernard Q. Li, Erik R. Scott, Phillip C. Falkner, Xuan K. Wei, Eric H. Bonde, David A. Dinsmoor, Duane L. Bourget, Forrest C M Pape, Gabriela C. Molnar, Joel A. Anderson, Michael J. Ebert, Richard T. Stone, Shawn C. Kelley, Stephen J. Roddy, Timothy J. Denison, Todd V. Smith
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Patent number: 11957894Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.Type: GrantFiled: August 25, 2020Date of Patent: April 16, 2024Assignee: Medtronic, Inc.Inventors: Anthony M. Chasensky, Bernard Q. Li, Brad C. Tischendorf, Chris J. Paidosh, Christian S. Nielsen, Craig L. Schmidt, David A. Dinsmoor, Duane L. Bourget, Eric H. Bonde, Erik R. Scott, Forrest C M Pape, Gabriela C. Molnar, Gordon O. Munns, Joel A. Anderson, John E. Kast, Joseph J. Viavattine, Markus W. Reiterer, Michael J. Ebert, Phillip C. Falkner, Prabhakar A. Tamirisa, Randy S. Roles, Reginald D. Robinson, Richard T. Stone, Shawn C. Kelley, Stephen J. Roddy, Thomas P. Miltich, Timothy J. Denison, Todd V. Smith, Xuan K. Wei
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Patent number: 11957609Abstract: A delivery device for controllably delivering multiple implants (e.g., intravascular implants) is described herein. The delivery device may include a lockout mechanism to prevent against inadvertent implant deployment prior to initial use. The delivery device may also include a re-sheath mechanism to allow for re-sheathing of an inner core assembly prior to removal of the delivery device from an initial deployment site. The delivery device may also further include a mechanism configured to prevent against re-sheathing of a partially-deployed implant.Type: GrantFiled: December 21, 2020Date of Patent: April 16, 2024Assignee: INTACT VASCULAR, INC.Inventors: Michael A. Longo, Chad J. Smith, Igor Tentler, Michael A. Dotsey, Evan E. Aamodt, Leif E. Malm, Kevin Y. Shin, Erin H. Morrissey, Patrick B. Nolan, Noah E. Dingler
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Publication number: 20240116972Abstract: The present disclosure is concerned with 6-aza-nucleoside prodrugs that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, yellow fever virus, tick-borne encephalitis virus, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), Middle East Respiratory Syndromes (MERS), Severe Acute Respiratory Syndrome (SARS), and coronavirus disease 2019 (COVID-19), using these compounds.Type: ApplicationFiled: November 15, 2023Publication date: April 11, 2024Inventors: Omar Moukha-Chafiq, Ashish Kumar Pathak, Shuklendu D. Karyakarte, Larry D. Bratton, Corinne E. Augelli-Szafran, Michael Diamond, Pei Yong Shi, Alec Jay Hirsch, Jessica Lee Smith, Daniel Streblow, Nicole Haese, Baoling Ying
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Patent number: 11949124Abstract: New and/or improved coatings, layers or treatments for porous substrates, including battery separators or separator membranes, and/or coated or treated porous substrates, including coated battery separators, and/or batteries or cells including such coatings or coated separators, and/or related methods including methods of manufacture and/or of use thereof are disclosed. Also, new or improved coatings for porous substrates, including battery separators, which comprise at least a matrix material or a polymeric binder, and heat-resistant particles with additional additives, materials or components, and/or to new or improved coated or treated porous substrates, including battery separators, where the coating comprises at least a matrix material or a polymeric binder, and heat-resistant particles with additional additives, materials or components are disclosed.Type: GrantFiled: January 4, 2019Date of Patent: April 2, 2024Assignee: Celgard, LLCInventors: Zhengming Zhang, Michael B. Lane, Insik Jeon, Edward Kruger, Xiang Yu, Ronnie E. Smith, Stefan Reinartz, Junqing Ma, Daniel R. Alexander
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Publication number: 20240100781Abstract: Improved battery separators, base films or membranes, batteries, cells, devices, systems, vehicles, and/or methods of making and/or using such separators, films or membranes, batteries, cells, devices, systems, vehicles, and/or methods of enhancing battery or cell charge rates, charge capacity, and/or discharge rates, and/or methods of improving batteries, systems including such batteries, vehicles including such batteries and/or systems, and/or the like; biaxially oriented porous membranes, composites including biaxially oriented porous membranes, biaxially oriented microporous membranes, biaxially oriented macroporous membranes, battery separators with improved charge capacities and the related methods and methods of manufacture, methods of use, and the like; flat sheet membranes, liquid retention media; dry process separators; biaxially stretched separators; dry process biaxially stretched separators having a thickness range between about 5 ?m and 50 ?m, preferably between about 10 ?m and 25 ?m, having impType: ApplicationFiled: December 4, 2023Publication date: March 28, 2024Inventors: Xiaomin Zhang, Gerald P. Rumierz, Karl F. Humiston, Charles E. Haire, Tyrone S. Fields, Michael A. Braswell, Ronald A. Proctor, Ronnie E. Smith
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Publication number: 20240094233Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.Type: ApplicationFiled: July 18, 2023Publication date: March 21, 2024Inventors: Jacob N. WOHLSTADTER, Manish KOCHAR, Peter J. BOSCO, Ian D. CHAMBERLIN, Bandele JEFFREY-COKER, Eric M. JONES, Gary I. KRIVOY, Don E. KRUEGER, Aaron H. LEIMKUEHLER, Pei-Ming WU, Kim-Xuan NGUYEN, Pankaj OBEROI, Louis W. PANG, Jennifer PARKER, Victor PELLICIER, Nicholas SAMMONS, George SIGAL, Michael L. VOCK, Stanley T. SMITH, Carl C. STEVENS, Rodger D. OSBORNE, Kenneth E. PAGE, Michael T. WADE, Jon WILLOUGHBY, Lei WANG, Xinri CONG, Kin NG
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Patent number: 11934161Abstract: System and method provide wireless distributed lighting control systems implementing a secure peer-to-peer, self-organizing and self-healing mesh network of actuators and system inputs. The system and method can be designed specifically for indoor and outdoor lighting where actuators include in-fixture, on-fixture and circuit control modules with ON/OFF and full range dimming capabilities, and system inputs include occupancy/vacancy sensors, daylight sensors and switches. A unique messaging protocol facilitates wireless and wired communication between actuators and system inputs, and provides web-based commissioning and monitoring of the lighting control system using a wireless access point accessible from a local network or Internet which can provide an intuitive and easy to use Graphical User Interface (GUI).Type: GrantFiled: November 30, 2021Date of Patent: March 19, 2024Assignee: HLI SOLUTIONS, INC.Inventors: Theodore E. Weber, Terrence R. Arbouw, Ronald K. Bender, Ronald J. Cummings-Kralik, Michael D. Crane, Thomas J. Hartnagel, Robert A. Martin, Peter A. Moyle, Gregory F. Smith, Stephan K. Zitz
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Patent number: 11535818Abstract: A composition, kit and method useful in a multi-stage washing method for cleaning an aluminum or aluminum alloy containers while reducing hazardous exposure of workers to toxic levels of hydrogen fluoride or ammonium bifluoride employs a stable, neutralized ammonium bifluoride-containing accelerator solution for addition to an acidic wash solution.Type: GrantFiled: November 29, 2018Date of Patent: December 27, 2022Assignee: HOUGHTON TECHNICAL CORP.Inventors: Laine Stewart, Michael E. Smith, Kimberly A. Kontra, Richard Hills
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Publication number: 20220112448Abstract: A composition, kit and method useful in a multi-stage washing method for cleaning an aluminum or aluminum alloy containers while reducing hazardous exposure of workers to toxic levels of hydrogen fluoride or ammonium bifluoride employs a stable, neutralized ammonium bifluoride-containing accelerator solution for addition to an acidic wash solution.Type: ApplicationFiled: December 20, 2021Publication date: April 14, 2022Inventors: Laine STEWART, Michael E. SMITH, Kimberly A. KONTRA, Richard HILLS
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Patent number: 10935499Abstract: Described are sensors and methods of detecting hydrogen gas. The sensor includes a polymer matrix and a dye molecule in an amount sufficient such that exposure of the polymer matrix to hydrogen gas causes a change in a spectroscopic property of the dye molecule wherein the spectroscopic property includes at least one of color, absorbance, or luminescence. The polymer matrix may further include a catalyst, such as a transition metal, sulfonated Wilkinson's catalyst, colloidal Pt, sulfonated iridium cyclooctadiene triphenylphosphine, sulfonated rhodium cyclooctadiene triphenylphosphine, sulfonated ruthenium triphenylphosphine, or combinations thereof. Embodiments of the sensor may further include a gas permeable, water impermeable membrane, an outer covering, or combinations thereof.Type: GrantFiled: September 27, 2018Date of Patent: March 2, 2021Assignee: University of CincinnatiInventors: William R. Heineman, John A. Lynch, Daniel P. Rose, Julia Kuhlmann, Daoli Zhao, Peng Zhang, Michael E. Smith
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Publication number: 20200385655Abstract: A composition, kit and method useful in a multi-stage washing method for cleaning an aluminum or aluminum alloy containers while reducing hazardous exposure of workers to toxic levels of hydrogen fluoride or ammonium bifluoride employs a stable, neutralized ammonium bifluoride-containing accelerator solution for addition to an acidic wash solution.Type: ApplicationFiled: November 29, 2018Publication date: December 10, 2020Inventors: Laine STEWART, Michael E. SMITH, Kimberly A. KONTRA, Richard HILLS
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Publication number: 20190094147Abstract: Described are sensors and methods of detecting hydrogen gas. The sensor includes a polymer matrix and a dye molecule in an amount sufficient such that exposure of the polymer matrix to hydrogen gas causes a change in a spectroscopic property of the dye molecule wherein the spectroscopic property includes at least one of color, absorbance, or luminescence. The polymer matrix may further include a catalyst, such as a transition metal, sulfonated Wilkinson's catalyst, colloidal Pt, sulfonated iridium cyclooctadiene triphenylphosphine, sulfonated rhodium cyclooctadiene triphenylphosphine, sulfonated ruthenium triphenylphosphine, or combinations thereof. Embodiments of the sensor may further include a gas permeable, water impermeable membrane, an outer covering, or combinations thereof.Type: ApplicationFiled: September 27, 2018Publication date: March 28, 2019Inventors: William R. Heineman, John A. Lynch, Daniel P. Rose, Julia Kuhlmann, Daoli Zhao, Peng Zhang, Michael E. Smith
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Publication number: 20170253420Abstract: A blood test strip dispenser is provided. The dispenser includes a body having an inner volume and an aperture extending from the inner volume through an outer surface of the body. A plurality of blood test strips are temporarily retained within the inner volume of the body of the dispenser. An actuating device operates to dispense a single blood test strip from within the inner volume through the aperture. A lifting device operates to lift the remaining blood test strips of the plurality of blood test strips after the single blood test strip has been dispensed. Lifting the remaining blood test strips aligns the top blood test strip of the remaining blood test strips with the aperture.Type: ApplicationFiled: March 2, 2017Publication date: September 7, 2017Inventor: Michael E. Smith
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Patent number: 8529214Abstract: A pump system including a pump and a sensor system for monitoring a fluid production of the pump and providing an output indicative of the fluid production. The sensor system is configured to use at least two discreet methodologies for measuring the fluid production. The pump system further includes a control system operatively coupled to the sensor system and the pump and configured to automatically vary the speed of the pump at least partially based upon the output of the sensor system.Type: GrantFiled: March 11, 2010Date of Patent: September 10, 2013Assignee: Robbins & Myers Energy Systems L.P.Inventor: Michael E. Smith
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Patent number: 8174410Abstract: An improved keyboard layout for use with information handling systems such as ultra mobile information handling systems. The improved keyboard layout eliminates the numbered function key (F1-F12) row and maps all of the functions that have traditionally been function (Fn) options on the F1-F12 row (such as brightness, volume, battery meter, etc.) to other keys.Type: GrantFiled: January 16, 2009Date of Patent: May 8, 2012Assignee: Dell Products L.P.Inventors: Erin K. Walline, Michael E. Smith, Justin Lyles
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Publication number: 20110223037Abstract: A pump system including a pump and a sensor system for monitoring a fluid production of the pump and providing an output indicative of the fluid production. The sensor system is configured to use at least two discreet methodologies for measuring the fluid production. The pump system further includes a control system operatively coupled to the sensor system and the pump and configured to automatically vary the speed of the pump at least partially based upon the output of the sensor system.Type: ApplicationFiled: March 11, 2010Publication date: September 15, 2011Applicant: ROBBINS & MYERS ENERGY SYSTEMS L.P.Inventor: Michael E. Smith
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Publication number: 20100182169Abstract: An improved keyboard layout for use with information handling systems such as ultra mobile information handling systems. The improved keyboard layout eliminates the numbered function key (F1-F12) row and maps all of the functions that have traditionally been function (Fn) options on the F1-F12 row (such as brightness, volume, battery meter, etc.) to other keys.Type: ApplicationFiled: January 16, 2009Publication date: July 22, 2010Inventors: Erin K. Walline, Michael E. Smith, Justin Lyles
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Patent number: D638418Type: GrantFiled: September 22, 2010Date of Patent: May 24, 2011Assignee: Dell Products L.P.Inventors: Weijong Sheu, Dimitre D. Mehandjiysky, Gabor Zanoni, Jan Schminke, Jason Cooper, Mark Matthews, Michael E. Smith