Patents by Inventor Michael F. Holick

Michael F. Holick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140309201
    Abstract: Methods for enhancing the ability of an individual, exposed to sunlight, to produce vitamin D via the skin. Pharmaceutical compositions comprising provitamin D and at least one of lumisterol and tachysterol and analogs and derivatives thereof are also disclosed.
    Type: Application
    Filed: June 30, 2014
    Publication date: October 16, 2014
    Inventor: Michael F. HOLICK
  • Publication number: 20130172847
    Abstract: Methods for enhancing the ability of an individual, exposed to sunlight, to produce vitamin D via the skin. Pharmaceutical compositions comprising provitamin D and at least one of lumisterol and tachysterol and analogs and derivatives thereof are also disclosed.
    Type: Application
    Filed: September 25, 2012
    Publication date: July 4, 2013
    Inventor: Michael F. HOLICK
  • Publication number: 20120041524
    Abstract: Methods for enhancing the ability of an individual, exposed to sunlight, to produce vitamin D via the skin. Pharmaceutical compositions comprising provitamin D and at least one of lumisterol and tachysterol and analogs and derivatives thereof are also disclosed.
    Type: Application
    Filed: July 13, 2011
    Publication date: February 16, 2012
    Inventor: Michael F. Holick
  • Publication number: 20090082451
    Abstract: The present invention is directed to the use of thyroid hormone conversion inhibitors to treat hyperproliferative skin disorders, preferably their use in topical admixtures.
    Type: Application
    Filed: August 30, 2005
    Publication date: March 26, 2009
    Applicant: Trustees of Boston University
    Inventors: Joshua D. Safer, Michael F. Holick
  • Publication number: 20080221071
    Abstract: Methods for enhancing the ability of an individual, exposed to sunlight, to produce vitamin D via the skin. Pharmaceutical compositions comprising provitamin D and at least one of lumisterol and tachysterol and analogs and derivatives thereof are also disclosed.
    Type: Application
    Filed: May 19, 2008
    Publication date: September 11, 2008
    Inventor: Michael F. Holick
  • Patent number: 7217696
    Abstract: Disclosed are glycosides, orthoester glycosides and glycuronamides of fluoxetine and analogs thereof to treat conditions and diseases such as depression.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: May 15, 2007
    Assignee: A & D Bioscience, Inc.
    Inventors: Michael F Holick, Halasya Ramanathan
  • Patent number: 6916791
    Abstract: Androgen glycosides provide free, circulatory androgen on oral administration as they are subject to less, first pass breakdown by the liver.
    Type: Grant
    Filed: May 30, 2003
    Date of Patent: July 12, 2005
    Assignee: Strakan Limited
    Inventors: Michael F. Holick, John Kanis
  • Publication number: 20040087559
    Abstract: Methods for inhibiting, preventing, or treating cancer cell growth are disclosed. In one embodiment, the method comprises the step of administering to a patient an effective amount of a metabolic precursor of 1,25-dihydroxyvitamin D, or an analog or a derivative thereof, to increase levels of the metabolic precursor available to a target cell. In a preferred embodiment, the metabolic precursor is 25-hydroxyvitamin D.
    Type: Application
    Filed: October 28, 2003
    Publication date: May 6, 2004
    Inventors: Gary G. Schwartz, Balakrishna L. Lokeshwar, Tai C. Chen, Lyman W. Whitlatch, Michael F. Holick
  • Publication number: 20040022838
    Abstract: Methods are disclosed for the regulation of cell differentiation and proliferation, e.g., for treating hyperproliferative skin disorders, such as psoriasis, for enhancing wound healing, for stimulating hair growth and inhibiting hair growth, by topical administration of parathyroid hormone (PTH), parathyroid related peptide (PTHrP), or fragment, analog or derivative thereof, and salts thereof, encapsulated by liposomes.
    Type: Application
    Filed: May 28, 2003
    Publication date: February 5, 2004
    Inventor: Michael F. Holick
  • Publication number: 20040013719
    Abstract: Methods are disclosed for the regulation of cell differentiation and proliferation, e.g., for treating hyperproliferative skin disorder, such as psoriasis, and skin cancer for enhancing wound healing, for stimulating hair growth and inhibiting hair growth, by administration of nucleic acid molecules encoding parathyroid hormone (PTH), parathyroid related peptide (PTHrP), or fragment, analog or derivative thereof, and salts thereof, encapsulated by particular liposomes or incorporated into a porous biocompatable matrix.
    Type: Application
    Filed: July 23, 2003
    Publication date: January 22, 2004
    Inventor: Michael F. Holick
  • Publication number: 20030220308
    Abstract: Methods for enhancing the ability of an individual, exposed to sunlight, to produce vitamin D via the skin. Pharmaceutical compositions comprising provitamin D and at least one of lumisterol and tachysterol and analogs and derivatives thereof are also disclosed.
    Type: Application
    Filed: May 22, 2003
    Publication date: November 27, 2003
    Inventor: Michael F. Holick
  • Publication number: 20030216328
    Abstract: Androgen glycosides provide free, circulatory androgen on oral administration as they are subject to less, first pass breakdown by the liver.
    Type: Application
    Filed: May 30, 2003
    Publication date: November 20, 2003
    Applicant: Strakan Limited, a Bermuda Corporation
    Inventors: Michael F. Holick, John Kanis
  • Patent number: 6630453
    Abstract: Androgen glycosides provide free, circulatory androgen on oral administration as they are subject to less, first pass breakdown by the liver.
    Type: Grant
    Filed: May 4, 2000
    Date of Patent: October 7, 2003
    Assignee: Strakan Limited
    Inventors: Michael F. Holick, John Kanis
  • Patent number: 6455714
    Abstract: Biotin, fluorescent and chemiluminescent labeled vitamin D compounds are disclosed as well as their use in assays for the presence of vitamin D, its metabolites and vitamin D analogs in biological fluids.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: September 24, 2002
    Assignee: A & D BioScience, Inc.
    Inventors: Michael F. Holick, Rahul Ray
  • Publication number: 20020107411
    Abstract: Biotin, fluorescent and chemiluminescent labeled vitamin D compounds are disclosed as well as their use in assays for the presence of vitamin D, its metabolites and vitamin D analogs in biological fluids.
    Type: Application
    Filed: March 19, 2001
    Publication date: August 8, 2002
    Inventors: Michael F. Holick, Rahul Ray
  • Publication number: 20020002140
    Abstract: Glycosides and orthoester glyco side derivatives of bisphosphonate compounds useful for treating and/or preventing hypercalcaemia of malignancy, Paget's disease, osteoporosis, metastatic cancer in bone and soft tissue and periodontal disease have markedly enhanced intestinal absorption and enhanced bioavailability.
    Type: Application
    Filed: January 16, 2001
    Publication date: January 3, 2002
    Inventors: Michael F. Holick, Halasya Ramanathan, George M. Blackburn
  • Publication number: 20010041676
    Abstract: Serum levels of therapeutically useful glucocorticosteroids are substantially increased by oral administration of the corresponding glycoside or orthoester glycoside.
    Type: Application
    Filed: January 16, 2001
    Publication date: November 15, 2001
    Inventors: Michael F. Holick, Halasya Ramanathan
  • Patent number: 6291693
    Abstract: Kit comprising biotin, fluorescent and chemiluminescent labeled vitamin D compounds are disclosed. The disclosed kit may be used in assays for the presence of vitamin D, its metabolites and vitamin D analogs in biological fluids.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: September 18, 2001
    Assignee: A & D BioScience, Inc.
    Inventors: Michael F. Holick, Rahul Ray
  • Patent number: 6229030
    Abstract: Kit comprising biotin, fluorescent and chemiluminescent labeled vitamin D compounds are disclosed. The disclosed kit may be used in assays for the presence of vitamin D, its metabolites and vitamin D analogs in biological fluids.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: May 8, 2001
    Assignee: A & D BioScience, Inc.
    Inventors: Michael F. Holick, Rahul Ray
  • Patent number: 6066618
    Abstract: Disclosed are methods of inhibiting proliferation and enhancing differentiation of a mammalian cell, inducing proliferation of a mammalian cell, enhancing wound healing, and stimulating hair growth using a peptide which has a 10% or greater homology to a region of human parathryoid hormone or human hypercalcemic factor.
    Type: Grant
    Filed: November 13, 1998
    Date of Patent: May 23, 2000
    Inventor: Michael F. Holick