Patents by Inventor Michael F. Holick

Michael F. Holick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vitamin D glycosides and a method of use
    Patent number: 4410515
    Abstract: A synthetic compound which is biologically active in maintaining calcium and phosphorous metabolism in animals, of the formula I ##STR1## wherein the double bond between positions C-22 and C-23 is single or double; R.sup.2 is hydrogen, CH.sub.3 or CH.sub.2 CH.sub.3 ; X is selected from the group consisting of hydrogen and --OR.sup.1, where R.sup.1 is hydrogen or a straight or branched chain glycosidic residue containing 1-20 glycosidic units per residue; with the proviso that at least one of the R.sup.1 is a glycosidic residue.
    Type: Grant
    Filed: April 1, 1981
    Date of Patent: October 18, 1983
    Assignee: Massachusetts General Hospital
    Inventors: Sally A. Holick, Michael F. Holick
  • Sunscreening agent
    Patent number: 4338293
    Abstract: A sunscreening composition which comprises a sunscreening amount of a .DELTA..sup.5,7 steroidal diene and a topical carrier, with the proviso that the .DELTA..sup.5,7 steroidal diene is not a precursor to a biologically active vitamin D compound.
    Type: Grant
    Filed: February 25, 1981
    Date of Patent: July 6, 1982
    Assignee: Massachusetts General Hospital
    Inventor: Michael F. Holick
  • Administration of biologically active vitamin D.sub.3 and vitamin D.sub.2 materials
    Patent number: 4335120
    Abstract: A process for administering biologically active vitamin D.sub.3 and vitamin D.sub.2 materials into the blood system of a subject by providing the biologically active vitamin D.sub.3 or D.sub.2 material to the skin whereby the skin releases the biologically active vitamin D.sub.3 or D.sub.2 material into the blood system in a controlled and prolonged manner.
    Type: Grant
    Filed: November 3, 1980
    Date of Patent: June 15, 1982
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael F. Holick, Milan R. Uskokovic
  • Sunscreen compositions containing .DELTA..sup.5,7 steroidal dienes
    Patent number: 4310511
    Abstract: A sunscreening composition which comprises a sunscreening amount of an opacifying agent and a therapeutic amount of a .DELTA..sup.5,7 steroidal diene which is non-hydroxylated at any of positions 1; 1,25; 1,24,25 or 1,25,26 thereof.
    Type: Grant
    Filed: October 2, 1980
    Date of Patent: January 12, 1982
    Assignee: Massachusetts General Hospital
    Inventor: Michael F. Holick
  • Administration of biologically active vitamin D.sub.3 and vitamin D.sub.2 materials
    Patent number: 4230701
    Abstract: A process for administering biologically active vitamin D.sub.3 and vitamin D.sub.2 materials into the blood system of a subject by providing the biologically active vitamin D.sub.3 or D.sub.2 material to the skin whereby the skin releases the biologically active vitamin D.sub.3 or D.sub.2 material into the blood system in a controlled and prolonged manner.
    Type: Grant
    Filed: March 21, 1979
    Date of Patent: October 28, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael F. Holick, Milan R. Uskokovic