Abstract: A catheter device for implanting a medical implant such as a prosthetic heart valve has a handle configured to control/steer multiple sheaths of the catheter device. A handle includes a grip portion, a rotatable deployment knob and a traveler. An outer sheath is connected to the traveler and the deployment knob is operatively connected to the traveler such that the traveler and thereby the outer sheath are moved along the longitudinal axis with respect to the inner sheath. The handle includes a rotatable axial positioning knob and a rotatable deflection knob. The deployment knob is arranged proximally to the axial positioning knob.

Abstract: The invention relates to a method for operating a fuel injection system (1) for supplying a combustion engine of a vehicle with fuel, in which method the fuel is conveyed at high pressure with the aid of a high-pressure pump (2), fed to a high-pressure accumulator (3), and injected into a cylinder of the combustion engine with the aid of at least one injector connected to the high-pressure accumulator (3). In order to detect any damage to the drive of the high-pressure pump (3), according to the invention a) the pressure (P) in the high-pressure accumulator (3) is measured and, on the basis of the measured values, a pressure drop (?P) in the high-pressure accumulator (3) caused by an injection into a cylinder is determined, b) a maximum pressure gradient is determined during a pressure build-up phase following the injection, c) the determined pressure drop (?P) and the determined maximum pressure gradient are put into proportion.

Abstract: The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for neutralization activity against a plurality of HIV-1 species, cloning a memory B cell that exhibits broad neutralization activity; and rescuing a monoclonal antibody from that memory B cell culture. The resultant monoclonal antibodies may be characterized by their ability to selectively bind epitopes from the Env proteins in native or monomeric form, as well as to inhibit infection of HIV-1 species from a plurality of clades. Compositions containing human monoclonal anti-HIV antibodies used for prophylaxis, diagnosis and treatment of HIV infection are provided. Methods for generating such antibodies by immunization using epitopes from conserved regions within the variable loops of gp120 are provided. Immunogens for generating anti-HIV1 bNAbs are also provided. Furthermore, methods for vaccination using suitable epitopes are provided.

Abstract: A system, method, and computer-readable medium are disclosed for performing a data center connectivity management operation. The connectivity management operation includes: providing a data center asset with a connectivity management system client; establishing a secure communication channel between the connectivity management system client and a connectivity management system; exchanging information between the connectivity management system client and the connectivity management system via the secure communication channel between the connectivity management system client and the connectivity management system, the information including a provisioning request; and, providing provisioning information to the data center asset via the secure communication channel.

Abstract: A method for autoconfiguration of a plurality of nodes in a linear network allows extracting the address and position of each node. The method includes applying an identifier field for transmitting to the bus the bit sequence of the identifier of a chosen node. Then for at least for the first node to the last but one node, a field comprising a predetermined bit sequence is applied. The field comprises dominant bits, so a current is transmitted. Then, a further field is applied for transmitting any stored direction bit associated to that node and obtained in any previous iteration. The iteration continues by choosing a node different from a node chosen in any previous cycle, starting the communication, until all nodes are identified.

Abstract: A method for autoconfiguration of a plurality of nodes in a linear network allows extracting the address and position of each node. The nodes are identified by a unique identifier. The method comprises choosing a node in a network and extracting its identifier, and for the first node to the last but one node, transmitting a current in the network from the chosen node, and reading the direction of the current flowing through at least the nodes not chosen in previous iteration cycles. The identifier is linked with the direction of the current for said not chosen nodes, obtaining the position of said not chosen nodes relative to the chosen node. These steps are repeated by choosing a different node not chosen before. Autoconfiguration is finished when the identifier of each node is extracted, and the physical position of each node is determined.

Abstract: A vehicle includes a primary axle, a secondary axle, and a powertrain. The powertrain has an engine coupled to the primary axle and selectively coupled to the secondary axle. The vehicle also includes a clutch associated with the secondary axle. A controller is programmed to, responsive to (i) a request to shift from two-wheel drive to four-wheel drive and (ii) a current engine-torque command exceeding a torque limit associated with the clutch, override the current engine-torque command to reduce a torque of the engine below the torque limit, and, responsive to the torque of the engine being less the torque limit, command engagement of the clutch.

Abstract: A safety related light system includes: one light source, a first control circuit, and a second control circuit. One of the first control circuit or the second control circuit is selectively enabled to operate in a drive mode to operate the one light source.

Abstract: A system and method for controlling a torque transfer clutch of a vehicle. A first data source indicates if the clutch is in AWD or 4×4 mode. An integrator system monitors energy transferred across the clutch. A temperature data source measures or calculates the clutch temperature. In a first case, the integrator accumulates data of the energy across the clutch during a monitoring period that is compared to a maximum accumulated energy value and initiates a powertrain torque dependent transfer point learn routine. In a second case, the controller responds to energy accumulator cycle data in a single monitoring cycle that is compared to a maximum cycle data value. In a third case, the controller responds to clutch temperature data and compares the temperature data to a maximum temperature value. The second and third cases initiate a non-powertrain torque dependent transfer point learn routine.

Abstract: The present disclosure refers to an implant needle (1) for introducing an implant into a body of a patient, comprising a receiving portion configured to receive an implant and provided in a hollow needle main body (2), and a taper-shaped tip portion (3). The taper-shaped tip portion (3) is further comprising: a first slant surface (14a) contiguous to a first outer peripheral surface (15) of the hollow needle main body (2), wherein the first slant surface (14a) is provided as a first non-cutting edge; a second slant surface (16a) contiguous to a second outer peripheral surface (17) of the hollow needle main body (2), wherein the second slant surface (16a) is provided as a second non-cutting edge; and a pair of sharpened surfaces (9a, 9b) symmetric with respect to an edge point (10) and a longitudinal axis (13) of the needle main body (2), wherein the sharpened surfaces (9a, 9b) are both provided with a cutting edge.

Abstract: Embodiments disclosed herein include headphone devices with spatially diverse antennas employing multiple operational modes and antenna switching policies. The headphone device may identify a current mode of operation and wirelessly communicate with at least one external device based at least in part on the current mode of operation. Further, operating in a first mode of operation, the headphone device may cause switching circuitry to selectively couple a first antenna to the common port in accordance with a first antenna switching policy. While operating in the second mode of operation, the headphone device may cause circuitry to selectively couple a second antenna to the common port in accordance with a second antenna switching policy that is different from the first antenna switching policy.

Abstract: A relative guide device (1) for a steering arrangement (31) is arranged on the wheel-carrier side for the spatial guidance and maintenance of the relative spatial orientation of the steering arrangement (31) with respect to a vehicle body (40). At least one telescopic movement apparatus (2) for movably connecting the steering arrangement (31) is arranged on the wheel-carrier side to the vehicle body (40). A steering force transmission device (30) transmits a steering force to a wheel (R) of a vehicle having a relative guide device (1), and to a wheel suspension (50) for a vehicle.

Abstract: Embodiments disclosed herein include headphone devices with spatially diverse antennas employing multiple operational modes and antenna switching policies. The headphone device may identify a current mode of operation and wirelessly communicate with at least one external device based at least in part on the current mode of operation. Further, operating in a first mode of operation, the headphone device may cause switching circuitry to selectively couple a first antenna to the common port in accordance with a first antenna switching policy. While operating in the second mode of operation, the headphone device may cause circuitry to selectively couple a second antenna to the common port in accordance with a second antenna switching policy that is different from the first antenna switching policy.

Abstract: An electrochemical sensor is disclosed. The sensor has a substrate having a proximal part and an elongated distal part. Electrodes are formed on the distal part. The working electrode forms a conductive trace and multiple electrode pads are arranged along and connected by conductive trace. The electrode pads include a corrosive conductive layer covered by a non-corrosive conductive layer. The corrosive conductive layer is a metal less noble or as noble as Ag, and the non-corrosive conductive is a metal more noble than Ag. An insulating layer on the substrate has openings in the areas of the electrode pads. A protective measure for the corrosive conductive layer can be provided, such as having the insulating layer at least partially overlap the electrode pad edges, or providing at least one of the electrode pads with an elongated shape along the smaller dimension of the distal part.

Abstract: An industrial truck having at least one hydraulic mast lift cylinder, which is connected to a hydraulic block via a hydraulic arrangement that limits a lowering speed of the mast lift cylinder. The hydraulic arrangement is formed to limit the lowering speed in a load-dependent manner to at least two maximum values. A first maximum value is given for the lowering speed at the nominal load while a second maximum value is given for the lowering speed with a load that is smaller than the nominal load, i.e., wherein the first maximum value is less than the second maximum value.

Abstract: A relative guide device (1) for a steering arrangement (31) is arranged on the wheel-carrier side for the spatial guidance and maintenance of the relative spatial orientation of the steering arrangement (31) with respect to a vehicle body (40). At least one telescopic movement apparatus (2) for movably connecting the steering arrangement (31) is arranged on the wheel-carrier side to the vehicle body (40). A steering force transmission device (30) transmits a steering force to a wheel (R) of a vehicle having a relative guide device (1), and to a wheel suspension (50) for a vehicle.

Abstract: Embodiments disclosed herein include headphone devices with spatially diverse antennas employing multiple operational modes and antenna switching policies. The headphone device may identify a current mode of operation and wirelessly communicate with at least one external device based at least in part on the current mode of operation. Further, operating in a first mode of operation, the headphone device may cause switching circuitry to selectively couple a first antenna to the common port in accordance with a first antenna switching policy. While operating in the second mode of operation, the headphone device may cause circuitry to selectively couple a second antenna to the common port in accordance with a second antenna switching policy that is different from the first antenna switching policy.

Abstract: A medical device (110) for detecting at least one analyte in a body fluid, a method of using a medical device (110) and a method for assembling a medical device are disclosed.

Abstract: A medical sensor assembly comprises a flexible plaster adapted for adhesion on the skin of a patient and a sensor configured for transdermal measuring a physiological parameter, wherein the sensor has a measuring part insertable into the skin and a contact part for providing a signal connection to a measuring unit. It is proposed that the plaster has a flap which is adhered to an intermediate section of the sensor between the measuring part and the contact part.

Abstract: Embodiments disclosed herein include headphone devices with spatially diverse antennas employing multiple operational modes and antenna switching policies. The headphone device may identify a current mode of operation and wirelessly communicate with at least one external device based at least in part on the current mode of operation. Further, operating in a first mode of operation, the headphone device may cause switching circuitry to selectively couple a first antenna to the common port in accordance with a first antenna switching policy. While operating in the second mode of operation, the headphone device may cause circuitry to selectively couple a second antenna to the common port in accordance with a second antenna switching policy that is different from the first antenna switching policy.