Patents by Inventor Michael Friedman

Michael Friedman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11238150
    Abstract: A medical device with limited computational capability includes medical hardware, a first register to store a static, substantially unique identifier of the medical device, a second register to store a static encryption key, an interface to receive and transmit data over a short-range communication link, and processing hardware. The processing hardware is configured to apply the static encryption key to the identifier of the medical device to generate an encrypted identifier, transmit the encrypted identifier of to another device via the interface, receive an encrypted identifier of the other device, decrypt the encrypted identifier of the other device using the static encryption key to determine an identifier of the other device, generate a dynamic encryption key using the identifier of the medical device and the identifier of the other device, and apply the dynamic encryption key to medical data transmitted between the medical device and the other device.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: February 1, 2022
    Assignee: AMGEN INC.
    Inventors: Huaying Yang, Andrew Dean, Ferry Tamtoro, Keng-Tong See, Michael Friedman, Desheng Yin, Huixing Jin, Edward Nielsen
  • Publication number: 20210315803
    Abstract: Provided herein are compositions of injectable antibiotics for veterinary use. The compositions are characterized by forming a gel at animal physiological temperature, said gel being characterized by a stable and repeatable release profile of the antibiotic. The compositions comprise high loading of drug in poloxamer solutions with addition of a co-solvent, and preferably with an addition of a cellulose derivative at least partially soluble in organic solvents. Methods of treatment of veterinary infections are also provided.
    Type: Application
    Filed: September 5, 2019
    Publication date: October 14, 2021
    Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Michael FRIEDMAN, David KIRMAYER, Zakhar NUDELMAN, Amnon HOFFMAN, Eran LAVY, Ayala BAR-HAI, Irith GATI
  • Patent number: 11103378
    Abstract: A medical appliance for the treatment of obstructive sleep apnea in a patient, the appliance comprising: a securing device configured to be removably affixed to the patient's jaw; and a biasing member which is insertable behind the soft palate and/or the base of the patient's tongue, thereby providing for the flow of air in the nasopharyngeal airway; wherein the securing device is connected to the biasing member to allow insertion and/or removal of the biasing member from the nasopharyngeal airway.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: August 31, 2021
    Assignee: Lumen Devices, LLC
    Inventors: John N. Irwin, Michael Friedman, J. Christopher Flaherty
  • Patent number: 11052043
    Abstract: A composition which comprises a biologically active agent and a polymer that exhibits a reverse thermal gelation at a physiological temperature, in a carrier, and in which the active agent is in an undissolved form is disclosed herein. Further disclosed herein are methods utilizing the compositions for treating subjects, including non-human subjects, as well as kits for preparing and using a composition. The composition is preferably a sustained release formulation, and is particularly useful for treating animals, where single-dose treatment is desired.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: July 6, 2021
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Michael Friedman, Amnon Hoffman, Eran Lavy
  • Publication number: 20210085514
    Abstract: A medical apparatus for the treatment of one or more sleep disorders such as obstructive sleep apnea in a patient is provided. The apparatus has an elongate member with a middle portion, a first fixation element and a second fixation element. The middle portion applies a force to a segment of a patient's airway.
    Type: Application
    Filed: April 17, 2020
    Publication date: March 25, 2021
    Inventors: J. Christopher Flaherty, John T. Garibotto, William J. Gorman, John N. Irwin, III, Michael Friedman
  • Publication number: 20200367632
    Abstract: A clipping device for securing an attached device is provided. The attached device is clipped to a clip target, such as a pocket edge, holster, utility webbing, belt strap, or other element commonly used to secure an attached device using a clipping device. A clip in the clipping device is configured to maintain tension against a clipping surface. To secure the device, the clip target is inserted between the clip and the clipping surface. The clipping device includes an integrated finger trap configured to facilitate manipulation of the attached device when the attached device is unclipped from the clip target. The attached device can be a smartphone and the clipping device can include a case for the smartphone as part of its structure.
    Type: Application
    Filed: May 19, 2020
    Publication date: November 26, 2020
    Applicant: Westa LLC
    Inventors: Michael Friedman, Craig Dennis
  • Patent number: 10843013
    Abstract: The present invention discloses liquid precursor compositions adapted for application on a hard surface in the oral cavity, comprising at least one therapeutic agent suitable for the treatment of oral disorders, at least one acidic-pH sensitive polymer, at least one hydrophobic polymer, and a pharmaceutically acceptable volatile carrier, wherein a weight ratio between said at least one hydrophobic polymer and said at least one acidic-pH sensitive polymer is larger than 1. The invention also discloses formulations formed of the solidification of these compositions, and methods for treating oral disorders by applying these compositions on hard surfaces in the oral cavity or to be placed in the oral cavity.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: November 24, 2020
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEWBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Michael Friedman, Doron Steinberg, Irith Gati
  • Publication number: 20200164145
    Abstract: A drug delivery device includes a housing, a drug delivery assembly disposed within the housing along a longitudinal axis, and a cap defining a shell. At least one electronic component, a power source, and a switch assembly are at least partially disposed in and coupled to the cap. The switch assembly is movable along a plane orthogonal to the longitudinal axis of the drug delivery assembly to cause the power source to provide power to the electronic component. The device further includes an activation mechanism at least partially disposed in the cap. Upon urging the cap along the longitudinal axis in a direction away from the housing, the activation mechanism engages the switch assembly and causes the switch assembly to move, thereby causing the power source to provide power to the at least one electronic component.
    Type: Application
    Filed: June 22, 2018
    Publication date: May 28, 2020
    Inventors: Sung Keun Chang, Flarold Dean, IV, Michael Friedman, Gordon Johnston, Neal Johnston
  • Patent number: 10660787
    Abstract: A medical apparatus for the treatment of one or more sleep disorders such as obstructive sleep apnea in a patient is provided. The apparatus has an elongate member with a middle portion, a first fixation element and a second fixation element. The middle portion applies a force to a segment of a patient's airway.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: May 26, 2020
    Assignee: Lumen Devices, LLC
    Inventors: J. Christopher Flaherty, John T. Garibotto, William J. Gorman, John N. Irwin, III, Michael Friedman
  • Publication number: 20200138621
    Abstract: A medical appliance for the treatment of one or more sleep disorders such as obstructive sleep apnea in a patient, the appliance comprising: a biasing member for inserting behind and exerting a force upon the patient's soft palate or tongue, wherein the biasing member is inserted in a reduced or minimized form and then expanded or firms once in place to exert the force. The appliance may be nasally inserted or be placed through the mouth. In a particular configuration, both the soft palate and tongue are biased to prevent obstruction of the flow of air in the nasopharyngeal airway.
    Type: Application
    Filed: September 9, 2019
    Publication date: May 7, 2020
    Inventors: Michael Friedman, John N. Irwin, III, William J. Gorman, John T. Garibotto, J. Christopher Flaherty
  • Patent number: 10632393
    Abstract: A mobile device (e.g., wireless wheeled vehicle) that includes one or more propulsion mechanisms (e.g., one or more drive wheels) and a member (e.g., a mechanized tail). The propulsion mechanism(s) are operable to propel the mobile device across a driving surface. The member is positionable to maintain or change an orientation of the mobile device with respect to the driving surface. The member has a base portion opposite a free end portion. The base portion is pivotably mounted to a portion of the mobile device. The base portion is pivotable to move the free end portion toward and away from the driving surface.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: April 28, 2020
    Assignee: Petronics Inc.
    Inventors: David Jun, Michael Friedman, David Cohen, Dario Aranguiz, Russell Jones
  • Patent number: 10485792
    Abstract: The present invention discloses a method of treating a head and neck cancer or preventing the development of pre-malignant lesions to this cancer, by administering locally to the oral cavity, a sustained release drug delivery system comprising a drug for the treatment of this cancer or for the prevention of said lesions, and at least one polymer, such that said system is attached to a surface in the oral cavity and remains attached thereto for at least 1 hour, accompanied by release of the drug and maintaining an effective therapeutic concentration thereof in the cavity, for at least 1 hour. Further are disclosed a sustained release drug delivery system and a liquid precursor varnish composition to this system.
    Type: Grant
    Filed: August 25, 2010
    Date of Patent: November 26, 2019
    Assignees: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED, YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Michael Friedman, Rakefet Czernimski, Silvio Gutkind, Doron Steinberg, Irith Gati, Zakhar Nudelman
  • Patent number: 10441457
    Abstract: A medical appliance for the treatment of one or more sleep disorders such as obstructive sleep apnea in a patient, the appliance comprising: a biasing member for inserting behind and exerting a force upon the patient's soft palate or tongue, wherein the biasing member is inserted in a reduced or minimized form and then expanded or firms once in place to exert the force. The appliance may be nasally inserted or be placed through the mouth. In a particular configuration, both the soft palate and tongue are biased to prevent obstruction of the flow of air in the nasopharyngeal airway.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: October 15, 2019
    Assignee: Lumen Devices LLC
    Inventors: Michael Friedman, John N. Irwin, III, William J. Gorman, John T. Garibotto, J. Christopher Flaherty
  • Publication number: 20190298649
    Abstract: Provided herein injectable implant compositions useful for acceleration of bone fracture healing, treatment of dental or oral pathologies, and controlled drug delivery.
    Type: Application
    Filed: September 19, 2017
    Publication date: October 3, 2019
    Inventors: Michael FRIEDMAN, David KIRMAYER, Rami MOSHEIFF, Jacob RACHMILEWITZ, Amal KHOURY, Doron STEINBERG
  • Publication number: 20190135836
    Abstract: This invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers, and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
    Type: Application
    Filed: December 21, 2018
    Publication date: May 9, 2019
    Inventors: Michael Friedman, Phil Cox, Kristine E. Frank, Michael Z. Hoemann, Augustine Osuma, Noel S. Wilson, Xiangdong Xu, Kevin Cusack, Raymond Huntley, J. Martin Herold
  • Patent number: 10273238
    Abstract: The disclosure provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the disclosure are useful for treating immunological and oncological conditions.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: April 30, 2019
    Assignee: AbbVie Inc.
    Inventors: Eric C. Breinlinger, Andrew Burchat, Justin Dietrich, Michael Friedman, David Ihle, David Kinsman, Kelly Mullen, Augustine Osuma, Anil Vasudevan, Noel S. Wilson
  • Publication number: 20190099523
    Abstract: The present invention discloses a liquid precursor composition adapted for application on a on a desired surface, this composition comprising: a. at least one therapeutic agent suitable for the treatment or prevention of a disorder or pathological condition, wherein said disorder or pathological condition excludes oral disorders, b. at least one acidic-pH sensitive polymer, c. at least one hydrophobic polymer, and d. a pharmaceutically acceptable volatile solvent, wherein a weight ratio between the at least one hydrophobic polymer and the at least one acidic-pH sensitive polymer is larger than 1.
    Type: Application
    Filed: October 9, 2018
    Publication date: April 4, 2019
    Inventors: Michael Friedman, Doron Steinberg, Eran Lavy
  • Publication number: 20190029923
    Abstract: Methods, systems and apparatuses are provided for producing delivery devices, preferably for oral intake of an agent. In the broadest aspect, the method comprises assembling one or more layers comprising one or more materials with an agent or an agent-releasing formulation to form an intergraded, preferably laminated device; folding said integrated delivery device to form a folded integrated delivery device; and at least partially enclosing said folded delivery device to a form suitable for oral delivery. Preferably, the integrated device comprise a first external layer of a first material; a frame of a second material mounted on the first external layer; an agent-releasing formulation housed within the frame; and a second external layer of the first material mounted on the frame.
    Type: Application
    Filed: October 1, 2018
    Publication date: January 31, 2019
    Applicant: INTEC PHARMA LTD.
    Inventors: Moshe TSABARI, Avner BALSHEY, Erez YOFE, Michael FRIEDMAN
  • Patent number: RE47221
    Abstract: The invention provides compounds of Formula (I) and Formula (II) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: February 5, 2019
    Assignee: AbbVie Inc.
    Inventors: Neil Wishart, Kristine E. Frank, Michael Friedman, Dawn M. George, Kent D. Stewart, Grier A. Wallace
  • Patent number: D905014
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: December 15, 2020
    Inventor: Michael Friedman