Abstract: A system and processes for the accurate measurement and control of image color values on a printing press with or without the presence of a color bar. More particularly, a universal closed loop color control system and processes for controlling the color quality of color images printed on a substrate online or offline, with or without a color bar printed on the substrate. The system may be run in a “Color Bar Mode” and scan simple rectangular color patches corresponding to each ink key in the print units, or can run in “Gray Spot Mode” and maintain overall target ink density values on the substrate as well as gray balance if the job has critical half tone images, or if the color bar is obtrusive on the job.

Abstract: The invention provides a compound of Formula (Ia), (Ib), (Ic), (Id), (Ie), (If), (Ig), (Ih), (Ii), (Ij), (Ik), or (Il) as defined herein, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

Abstract: A medical appliance for the treatment of obstructive sleep apnea in a patient, the appliance comprising: a securing device configured to be removably affixed to the patient's jaw; and a biasing member which is insertable behind the soft palate and/or the base of the patient's tongue, thereby providing for the flow of air in the nasopharyngeal airway; wherein the securing device is connected to the biasing member to allow insertion and/or removal of the biasing member from the nasopharyngeal airway.

Abstract: A topical sustained release delivery system for delivery of antifungal agents to the finger or toenails achieving high penetration through the nails by combining the antifungal agent with a keratolytic agent and a humectant. The pharmaceutical sustained release topical preparation is provided in a varnish or spray form for treating the nail and surrounding tissues, where the active ingredient is an antifungal agent, a keratolytic agent or combination thereof. The composition may further include an antibacterial, an antiviral, an antipsoriatic agents, or combinations thereof.

Abstract: A topical sustained release delivery system for delivery of antifungal agents to the finger or toenails achieving high penetration through the nails by combining the antifungal agent with a keratolytic agent and a humectant. The pharmaceutical sustained release topical preparation is provided in a varnish or spray form for treating the nail and surrounding tissues, where the active ingredient is an antifungal agent, a keratolytic agent, or preferably a combination of an antifungal and a keratolytic agent. The composition may further comprise an antibacterial, an antiviral, an antipsoriatic agents, or combinations thereof.

Abstract: A method and system providing a client with user interface information are described. The method and system implement a set of application program interfaces for providing user interface information to a client through an accessibility system. The accessibility system includes a mechanism for transferring user interface information from a provider side to the client side and a logical tree for selectively revealing user interface information. The application program interface system includes client side application program interfaces for assisting the client in obtaining user interface information. The client side application program interfaces include an automation class, a logical element class, a raw element class, control pattern classes, and an input class. The provider side application program interfaces include a provider automation class, a provider automation interface, a raw element interface, and control pattern provider interfaces.

Abstract: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

Abstract: The present invention related generally to thermoplastic films, and, more particularly, to low haze thermoplastic films with high thickness uniformity, methods for manufacturing low haze thermoplastic films with high thickness uniformity, and manufacturing systems for forming the same.

Abstract: A system and processes for the accurate measurement and control of image color values on a printing press with or without the presence of a color bar. More particularly, a barless color control system and processes for controlling the color quality of color images printed on a substrate online or offline, with or without a color bar printed on the substrate. The system provides an efficient and inexpensive method for barless closed loop color control and the processes are conducted without pixel-by-pixel comparisons.

Abstract: A universal console (UC) platform for a UC device is provided. The user sets up or initializes the UC by describing his or her preferences and disabilities. The UC digests and stores this user information. Later, as the user encounters various devices and applications to be controlled, and indicates a desire to control a particular device, the device to be controlled or other source sends a canonical user interface (UI) description of the device's UI to the UC. The canonical UI description adheres to an abstract format to describe in high-level terms the functionality of the device's UI. From the canonical UI representation, the UC device is capable of recognizing (1) the action-commands to which the device responds including parameters and (2) the decisions, selections, and input the user needs to provide for the console to determine which action-commands to send and the values of the action-command parameters.

Abstract: The present invention provides a gastro-retentive diagnostic assembly (GRDA) for use in determining a condition of a subject's gastrointestinal tract (GI tract), comprising a folded single or multi-layered device comprising a diagnostic utility, such as a contrasting agent, the device prior to folding being essentially planar, and included in a delivery system for oral intake, the delivery system being adapted to release the device once in the stomach, whereupon release said device unfolds into an unfolded shape that results in the retention of the device in the stomach. Further provided are methods of determining a condition of a subject's GI tract by the use of the GRDA of the invention, as well as uses of a single or multi-layered device comprising a diagnostic utility when in a folded or unfolded shape, and method of preparing the GRDA of the invention.

Abstract: The present invention is directed to novel aminopyrrolidines of formula I pharmaceutically acceptable salts thereof, metabolites thereof, isomers thereof, stereoisomers thereof or pro-drugs thereof, wherein the variables are as defined herein. The compounds of formula (I) are useful as chemokine receptor antagonists and as such would be useful in treating certain conditions and diseases, especially inflammatory conditions and diseases and proliferative disorders and conditions, for example, cancers.

Abstract: Novel compounds of Formula (I) or pharmaceutically acceptable salts thereof, metabolites thereof, isomers thereof, enantiomers thereof or prodrugs thereof of Formula (I) wherein the substituents are as defined herein, which are useful as therapeutic agents.

Abstract: Human prostate cancer (CaP) cells secrete biological activities that recruit cells to differentiate into the osteoblast lineage. Conditioned medium (CM) produced by metastatic human CaP cells (DuCaP and VCaP) induced commitment and differentiation of mesenchymal stem cells (MSC) into osteoblasts. CaP-CM induces cellular condensation into tissue-like aggregates. In turn, these tissue-like aggregates secrete and mineralize a bone matrix, forming bone outside the body (ex vivo). Thus, conditioned media and/or proteins isolated therefrom may be used to facilitate bone formation in fracture repair and bone diseases.

Abstract: A synthetic roofing shingle or tile is provided, in which a core material is formed, of generally less expensive material, and with a skin material provided, disposed on a plurality of surfaces of the shingle or tile, with the skin material being generally of greater expense and having desirable weather-withstanding qualities.

Abstract: A rolling case for a massage table comprises a substantially durable storage compartment which is sufficiently large to receive a folded massage table. In an exemplary embodiment, the storage compartment includes a bolster pillow pocket and a main pocket on the front side of the compartment. The storage compartment is affixed to a base member which includes a leg assembly and a rolling mechanism. A telescopic handle mechanism is attached to the base member.

Abstract: The invention relates to synchronous drug delivery composition comprising a polymeric matrix which comprises hydrogel blended with a hydrophobic polymer, so as to form an erodible matrix, a drug, and, optionally, an agent which enhances intestinal drug absorption and/or an agent which inhibits intestinal drug degradation, wherein erosion of the erodible matrix, permits synchronous release of the drug, the hydrogel and the intestinal drug absorption agent and/or the agent which inhibits intestinal drug degradation.

Abstract: A system and processes for the accurate measurement and control of image color values on a printing press with or without the presence of a color bar. More particularly, a barless color control system and processes for controlling the color quality of color images printed on a substrate online or offline, with or without a color bar printed on the substrate. The system provides an efficient and inexpensive method for barless closed loop color control and the processes are conducted without pixel-by-pixel comparisons.

Abstract: A system for the accurate measurement and control of image color density on an operating printing press. The method and apparatus control the printing of a multicolored image by controlling the amount of each of the inks used to print an image based on the color densities of each of the inks detected in printed images. The process includes controlling the positioning and linear movement of a strobe and a digital video camera across a substrate having images printed thereon; illuminating the images with a strobe; selecting and acquiring the images via a digital video camera and producing a digitized representation thereof; selecting a portion of the images; measuring and analyzing the color intensity of the selected portion of the images and producing reflective density values thereof, and storing said reflective density values in a first memory; comparing the reflective density values for the portion of the images to standard density values in a second memory for the portion of the images.

Abstract: A synthetic roofing shingle or tile is provided, in which a core material is formed, of generally less expensive material, and with a skin material provided, disposed on a plurality of surfaces of the shingle or tile, with the skin material being generally of greater expense and having desirable weather-withstanding qualities.