Patents by Inventor Michael Hamilton

Michael Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolopyrazine kinase inhibitors
    Patent number: 8658646
    Abstract: The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: February 25, 2014
    Assignee: Hoffmann-LaRoche Inc.
    Inventors: Shaoqing Chen, Javier de Vicente Fidalgo, Matthew Michael Hamilton, Johannes Cornelius Hermann, Joshua Kennedy-Smith, Hongju Li, Allen John Lovey, Matthew C. Lucas, Kin-Chun Thomas Luk, Stephen M. Lynch, Counde O'yang, Fernando Padilla, Ryan Craig Schoenfeld, Achyutharao Sidduri, Michael Soth, Ce Wang, Peter Michael Wovkulich, Xiaohu Zhang
  • PYRROLOPYRAZINE KINASE INHIBITORS
    Publication number: 20130059834
    Abstract: The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
    Type: Application
    Filed: August 31, 2012
    Publication date: March 7, 2013
    Inventors: Shaoqing Chen, Javier de Vicente Fidalgo, Matthew Michael Hamilton, Johannes Cornelius Hermann, Joshua Kennedy-Smith, Hongju Li, Allen John Lovey, Matthew C. Lucas, Kin-Chun Thomas Luk, Stephen M. Lynch, Counde O'yang, Fernando Padilla, Ryan Craig Schoenfeld, Achyutharao Sidduri, Michael Soth, Ce Wang, Peter Michael Wovkulich, Xiaohu Zhang
  • Adaptive traffic shaping for wireless communication systems
    Patent number: 8385199
    Abstract: Adaptive traffic shaping techniques, apparatuses, and systems can include obtaining information that associates mobile devices with wireless network areas handling wireless communications with the mobile devices and influencing data flow transmissions to the mobile devices associated with the wireless network areas based at least on the obtained information. Adaptive traffic shaping can include determining loading factors for the wireless network areas based on the associations. Techniques, apparatuses, and systems can control data flows to the mobile devices based on associated loading factors.
    Type: Grant
    Filed: January 21, 2010
    Date of Patent: February 26, 2013
    Assignee: Radisys Corporation
    Inventors: Michael Hamilton Coward, Manish Singh, Renuka Bhalerao
  • OPTIMIZING THE ACQUISITION OF GOODS
    Publication number: 20130013417
    Abstract: A facility is provided for adding, identifying, comparing, organizing, annotating, sharing and discovering goods to acquire. This facility provides users with the information and the ability to make informed goods acquisition decisions at the point of sale where they could not have done so previously. Through the system of goods organization, the user will be able to benefit from the identifiable information about the goods that they currently own when presented with new acquirable goods. Knowing the relations between the existing goods owned allows users to benefit from objective measurements of the likelihood of success or satisfaction when presented with a new acquisition target.
    Type: Application
    Filed: January 30, 2012
    Publication date: January 10, 2013
    Applicant: Ferucia LLC
    Inventors: Michael Hamilton Miller, Lisa Ann Miller, James Chia-Ming Liu, Alexander George Parakilas
  • Diacylglycerol acyltransferase inhibitors
    Patent number: 8324385
    Abstract: Provided herein are compounds of the formula (I): were RI is phenyl, R2 is hydrogen, halogen or lower alkyl, X is carbon on nitrogen, and R3 is isoquinoline, -amino, or a -4- to 6-membered heterocycloalkyl ring and pharmaceutically acceptable salts thereof, which are active as DGAT inhibitors and therefore find uses in treatment of diseases associated with abnormal metabolism of trigliceride. such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
    Type: Grant
    Filed: October 20, 2009
    Date of Patent: December 4, 2012
    Assignee: Madrigal Pharmaceuticals, Inc.
    Inventors: David Robert Bolin, Adrian Wai-Hing Cheung, Matthew Michael Hamilton, Nicholas Marcopulos, Lee Apostle McDermott, Yimin Qian
  • IRRIGATION APPARATUS
    Publication number: 20120167458
    Abstract: There is provided an irrigation apparatus. The irrigation apparatus is used to water trees.
    Type: Application
    Filed: June 11, 2010
    Publication date: July 5, 2012
    Inventors: Charles Simon James Agg, Michael Hamilton Russell
  • TREE ANCHORING KIT AND A STRAP TENSIONER FOR USE THEREWITH
    Publication number: 20120097080
    Abstract: There is provided a tree anchor system kit.
    Type: Application
    Filed: June 11, 2010
    Publication date: April 26, 2012
    Inventors: Charles Simon James Agg, Michael Hamilton Russell
  • Diacylglycerol acyltransferase inhibitors
    Patent number: 8153644
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: April 10, 2012
    Assignee: Madrigal Pharmaceuticals, Inc.
    Inventors: David Robert Bolin, Adrian Wai-Hing Cheung, Fariborz Firooznia, Matthew Michael Hamilton, Lee Aopstle McDermott, Yimin Qian, Jenny Tan, Weiya Yun
  • Diacylglycerol acyltransferase inhibitors
    Patent number: 8115011
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: February 14, 2012
    Assignee: Madrigal Pharmaceuticals, Inc.
    Inventors: David Robert Bolin, Adrian Wai-Hing Cheung, Fariborz Firooznia, Matthew Michael Hamilton, Lee Apostle McDermott, Yimin Qian, Jenny Tan, Weiya Yun
  • Diacylglycerol acyltransferase inhibitors
    Patent number: 8058299
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: November 15, 2011
    Assignee: VIA Pharmaceuticals, Inc.
    Inventors: David Robert Bolin, Adrian Wai-Hing Cheung, Fariborz Firooznia, Matthew Michael Hamilton, Lee Apostle McDermott, Yimin Qian, Jenny Tan, Weiya Yun
  • ANILINE ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS
    Publication number: 20110130438
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
    Type: Application
    Filed: October 20, 2010
    Publication date: June 2, 2011
    Inventors: David Robert Bolin, Matthew Michael Hamilton
  • Indole and indazole analogs as glycogen synthase activators
    Patent number: 7947728
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
    Type: Grant
    Filed: October 13, 2010
    Date of Patent: May 24, 2011
    Assignee: Hoffmann-La Roche Inc.
    Inventors: David Robert Bolin, Matthew Michael Hamilton, Lee Apostle McDermott, Lin Yi
  • Surgical Needle Coatings and Methods
    Publication number: 20110111116
    Abstract: The present invention provides improved medical devices for use in surgical procedures and methods for manufacturing improved medical devices. In some embodiments, the improved medical devices can include improved surgical needles that are capable of being repeatedly passed through tissue using minimal force. More particularly, the improved surgical needles can be manufactured with two or more different coatings that provide the surgical needles with both durability and lubricity for ease of repeated and successive passes through tissue. Improved methods for manufacturing the surgical needles and for providing and applying coatings to the surgical needles are also provided.
    Type: Application
    Filed: August 18, 2010
    Publication date: May 12, 2011
    Applicant: ETHICON, INC.
    Inventors: Robert Maurer, S. Neil Bar, Eric Hinrichs, Michael Hamilton, Thomas Wilkes
  • Surgical Needle Coatings and Methods
    Publication number: 20110112565
    Abstract: The present invention provides novel medical devices for use in surgical procedures and methods for manufacturing novel medical devices. In some embodiments, the novel medical devices can include surgical needles that are capable of being repeatedly passed through tissue using minimal force. More particularly, the surgical needles can be manufactured with one or more coatings that provide the surgical needles with both durability and lubricity for ease of repeated and successive passes through tissue. Novel methods for manufacturing the surgical needles and for providing and applying coatings to the surgical needles are also provided.
    Type: Application
    Filed: August 18, 2010
    Publication date: May 12, 2011
    Applicant: ETHICON, INC.
    Inventors: Robert Maurer, S. Neil Bar, Eric Hinrichs, Michael Hamilton, Thomas Wilkes
  • Surgical Needle Coatings and Methods
    Publication number: 20110112566
    Abstract: The present invention provides improved medical devices for use in surgical procedures and methods for manufacturing improved medical devices. In some embodiments, the improved medical devices can include improved surgical needles that are capable of being repeatedly passed through tissue using minimal force. More particularly, the improved surgical needles can be manufactured with two or more different coatings that provide the surgical needles with both durability and lubricity for ease of repeated and successive passes through tissue. Improved methods for manufacturing the surgical needles and for providing and applying coatings to the surgical needles are also provided.
    Type: Application
    Filed: August 18, 2010
    Publication date: May 12, 2011
    Applicant: ETHICON, INC.
    Inventors: Robert Maurer, S. Neil Bar, Eric Hinrichs, Michael Hamilton, Thomas Wilkes
  • INDOLE AND INDAZOLE ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS
    Publication number: 20110112161
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
    Type: Application
    Filed: October 13, 2010
    Publication date: May 12, 2011
    Inventors: David Robert Bolin, Matthew Michael Hamilton, Lee Apostle McDermott, Lin Yi
  • BENZISOXAZOLE ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS
    Publication number: 20110112158
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
    Type: Application
    Filed: October 13, 2010
    Publication date: May 12, 2011
    Inventors: David Robert Bolin, Matthew Michael Hamilton, Lee Apostle McDermott, Yimin Qian
  • Aniline analogs as glycogen synthase activators
    Patent number: 7939569
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
    Type: Grant
    Filed: October 20, 2010
    Date of Patent: May 10, 2011
    Assignee: Hoffmann-La Roche Inc.
    Inventors: David Robert Bolin, Matthew Michael Hamilton
  • FEEDING BOTTLE FOR BABIES
    Publication number: 20100213157
    Abstract: The invention relates to a baby feeding bottle and an assembly therefor. The baby feeding bottle includes a container and a teat unit. The teat unit includes a teat, a teat support and means for piercing a membrane arranged on the mouth of the container. The bottle further includes a teat unit and container separation resistance arrangement. The teat unit is configured so that the means for piercing the membrane pierce the membrane when the teat unit, or part thereof, is moved, in use, towards the membrane so that the baby feed is accessible through the teat.
    Type: Application
    Filed: March 19, 2008
    Publication date: August 26, 2010
    Inventor: John Michael Hamilton-Hall
  • HDD sector format with reduced vulnerability to defects and burst errors
    Patent number: 7774685
    Abstract: Modified HDD sector formats have multiple sets of preamble data. The preambles are well separated so that any defect long enough to wipe out both preambles would also overwhelm the ECC.
    Type: Grant
    Filed: August 8, 2005
    Date of Patent: August 10, 2010
    Assignee: Hitachi Global Storage Technologies Netherlands B.V.
    Inventors: Bruce Wilson, Richard Michael Hamilton New