Patents by Inventor Michael Harter

Michael Harter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydrobenzo[d]azepin-2-one derivatives and the use thereof for treating cardiovascular diseases
    Patent number: 7662956
    Abstract: The present application relates to novel tetrahydrobenzo[d]azepin-2-one derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, especially of dyslipidaemias, arteriosclerosis, restenosis and ischaemias.
    Type: Grant
    Filed: February 1, 2005
    Date of Patent: February 16, 2010
    Assignee: Bayer Shering Pharma AG
    Inventors: Nils Griebenow, Timo Flessner, Michael Härter, Martin Raabe, Anja Buchmüller, Hilmar Bischoff, Peter Ellinghaus, Peter Kolkhof
  • ARYL-SUBSTITUTED HETEROCYCLES, AND USE THEREOF
    Publication number: 20100029651
    Abstract: The invention relates to aryl-substituted heterocycles, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.
    Type: Application
    Filed: May 25, 2007
    Publication date: February 4, 2010
    Inventors: Michael Härter, Tobias Wunberg, Swen Allerheiligen, Marcus Bauser, Ulrich Rester, Stefan heitmeier
  • Tricyclic benzazepine derivatives and their use
    Publication number: 20090215743
    Abstract: The present application relates to novel tricyclic benzazepine derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, especially of dyslipidaemias, arteriosclerosis, restenosis and ischaemias.
    Type: Application
    Filed: December 31, 2004
    Publication date: August 27, 2009
    Applicant: Bayer HealthCare AG
    Inventors: Elisabeth Woltering, Michael Härter, Timo Flessner, Mario Jeske, Nils Griebenow, Frank Süssmeier, Hilmar Bischoff, Martin Raabe, Anja Buchmüller, Peter Kolkhof, Peter Ellinghaus, Olaf Weber
  • Isophthalic acid derivatives
    Patent number: 7498460
    Abstract: The present invention relates to isophthalic acid derivatives, to a process for their preparation and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular of cardiovascular disorders.
    Type: Grant
    Filed: November 28, 2003
    Date of Patent: March 3, 2009
    Assignee: Bayer Healthcare AG
    Inventors: Michael Härter, Jens Ergüden, Frank Wunder, Hanna Tinel, Johannes Köbberling, Eva-Maria Becker, Klaus Münter, Karl-Heinz Schlemmer, Raimund Kast, Peter Kolkhof, Gunter Karig, Lars Bärfacker, Walter Hübsch, Joachim Schuhmacher, Susanne Zuleger, Arnel Concepcion, Haruka Shimizu
  • Phenyl Acetamides
    Publication number: 20080176898
    Abstract: The present invention relates to phenylacetamides, to a process for their preparation and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, especially of cardiovascular disorders.
    Type: Application
    Filed: April 14, 2005
    Publication date: July 24, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Michael Harter, Frank Wunder, Lars Barfacker, Gunter Karig, Walter Hubsch, Hanna Tinel, Eva-Maria Becker
  • Methods for treating heart failure, thromboembolic disorders, and pulmonary fibrosis
    Patent number: 7329777
    Abstract: This invention relates to methods for treating heart failure, thromboembolic disorders, and pulmonary fibrosis, comprising administering an effective amount of a compound of formula (I) in which the several variables are as defined in the specification and claims.
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: February 12, 2008
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Harter, Michael Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
  • Tetrahydrobenzo(D)Azepin-2-One Derivatives and the Use Thereof for Treating Cardiovascular Diseases
    Publication number: 20070287698
    Abstract: The present application relates to novel tetrahydrobenzo[d]azepin-2-one derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, especially of dyslipidaemias, arteriosclerosis, restenosis and ischaemias.
    Type: Application
    Filed: February 1, 2005
    Publication date: December 13, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Nils Griebenow, Timo Flessner, Michael Harter, Martin Raabe, Anja Buchmuller, Hilmar Bischoff, Peter Ellinghaus, Peter Kolkhof
  • Substituted aminodicarboxylic acid derivatives having pharmaceutical properties
    Publication number: 20070179139
    Abstract: The invention relates to compounds of formula (I) and their salts and stereoisomers in which the variables are as defined in the description and claims, for producing medicaments used in the treatment of cardiovascular and other diseases. Such compounds, processes for preparing them, compositions containing them, and methods of using them are claimed.
    Type: Application
    Filed: October 10, 2006
    Publication date: August 2, 2007
    Applicant: Bayer Aktiengesellschaft
    Inventors: Cristina Alonso-Alija, Michael Harter, Michael Hahn, Josef Pernerstorfer, Stefan Weigand, Johannes-Peter Stasch, Frank Wunder
  • Biphenyl and biphenyl-analogous compounds as integrin antagonists
    Patent number: 7094911
    Abstract: The present invention relates to biphenyl and biphenyl-analogous compounds, their preparation and use as pharmaceutical compositions, as integrin antagonists and in particular for the production of pharmaceutical compositions for the treatment and prophylaxis of cancer, arteriosclerosis, restenosis, osteolytic disorders such as osteoporosis and ophthalmic diseases. The compounds according to the invention have the formula (1) wherein R1, R2, U, V, A, B, W, R3, C and R4 have the meaning as defined in the claims.
    Type: Grant
    Filed: October 31, 2002
    Date of Patent: August 22, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Markus Albers, Klaus Urbahns, Andrea Vaupel, Michael Härter, Delf Schmidt, Beatrix Stelte-Ludwig, Christoph Gerdes, Elke Stahl, Jörg Keldenich, Ulf Brueggemeier, Klemens Lustig
  • Isophtalic acid derivatives
    Publication number: 20060154912
    Abstract: The present invention relates to isophthalic acid derivatives, to a process for their preparation and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular of cardiovascular disorders.
    Type: Application
    Filed: November 28, 2003
    Publication date: July 13, 2006
    Inventors: Michael Harter, Jens Erguden, Frank Wunder, Hanna Tinel, Johannes Kobberling, Eva-Maria Becker, Klaus Munter, Karl-Heinz Schlemmer, Raimund Kast, Peter Kolkhof, Gunter Karig, Lars Barfacker, Walter Hubsch, Joachim Schuhmacher, Susanne Zuleger, Arnel Concepcion, Haruka Shimizu
  • Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases
    Patent number: 7067694
    Abstract: Compounds of the general formula (I) wherein R1 represents halogen, R2 and R3 represent H or halogen, and R4 represents C3-8-cycloalkyl or optionally substituted phenyl, pharamceutical compositions containing such materials, and methods of using such materials in the treatment of various diseases are disclosed and claimed.
    Type: Grant
    Filed: February 18, 2002
    Date of Patent: June 27, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Härter, Michael G. Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
  • Novel halogen-substituted aminodicarboxylic acid derivatives
    Publication number: 20060111444
    Abstract: This invention relates to methods for treating cardiovascular disorders selected from heart failure, thromboembolic disorders, venous diseases, and fibriotic disorders other than fibrosis of the liver, comprising administering an effective amount of a compound of formula (I) wherein the several variables are as defined in the specification and claims.
    Type: Application
    Filed: August 22, 2005
    Publication date: May 25, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Michael Harter, Michael Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
  • Novel aminodicarboxylic acid derivatives
    Publication number: 20050288366
    Abstract: This invention relates to methods for treating cardiovascular disorder selected from heart failure, thromboembolic disorders, venous diseases, and fibrotic disorders other than fibrosis of the liver, comprising administering an effective amount of a compound of formula (I) in which the several variables are as defined in the specification and claims.
    Type: Application
    Filed: August 22, 2005
    Publication date: December 29, 2005
    Applicant: Bayer Aktiengesellschaft
    Inventors: Michael Harter, Michael Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
  • Side-chain halogenated amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases
    Patent number: 6939989
    Abstract: Compounds of the general formula (I) wherein R1 represents halogen, R2 represent H or halogen, and R3 represents C3-8-cycloalkyl, C3-8-cycloalkenyl, or optionally substituted phenyl, pharmaceutical compositions containing such material, and methods of using such materials in the treatment of various diseases are disclosed and claimed.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: September 6, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Härter, Michael Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
  • Derivatives of dicarboxylic acid having pharmaceutical properties
    Patent number: 6939990
    Abstract: The invention relates to compounds of the general formula (I) wherein R1 represents H, halogen, or OCF3; R2 and R3 each represents H or halogen; R4 represents C1-6-alkyl, C3-8-cycloalkyl, CF3, OCF3, F, Cl, OMe, or optionally substituted phenyl; V represents O, CH2O, OCF2, or O—C1-6-alkyl-O; and W represents CH2 or CH2CH2. A process for making such compounds, pharmaceutical compositions containing them, and methods of treatment of various conditions using them are also disclosed and claimed.
    Type: Grant
    Filed: February 18, 2002
    Date of Patent: September 6, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Härter, Michael Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
  • Substituted alkyl uracils and thereof
    Publication number: 20050159431
    Abstract: The invention relates to novel compounds of formula (I), to a method for the production thereof, and to their use as medicament active ingredients for the prophylaxis and/or treatment of diseases.
    Type: Application
    Filed: January 3, 2003
    Publication date: July 21, 2005
    Applicant: Bayer Healthcare AG
    Inventors: Barbara Albrecht, Michael Gerisch, Michael Harter, Thomas Krahn, Felix Oehme, Karl-Heinz Schlemmer, Henning Steinhagen
  • Substituted amino dicarboxylic acid derivatives
    Publication number: 20040176446
    Abstract: The invention relates to compounds of formula (I), to salts and stereoisomers thereof, to their production and to their use for producing medicaments used for treating cardiovascular diseases.
    Type: Application
    Filed: April 12, 2004
    Publication date: September 9, 2004
    Inventors: Cristina Alonso-Alija, Michael Harter, Michael Hahn, Josef Pernerstorfer, Stefan Weigand, Johannes-Peter Stasch, Frank Wunder
  • Novel derivatives of dicarboxylic acid having pharmaceutical properties
    Publication number: 20040110840
    Abstract: The invention relates to compounds of formula (I), to a method for their production and to their use as medicaments.
    Type: Application
    Filed: August 29, 2003
    Publication date: June 10, 2004
    Inventors: Michael Harter, Michael Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
  • Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases
    Publication number: 20040092593
    Abstract: The invention relates to compounds of formula (I), to methods for their production and to the use thereof as medicaments.
    Type: Application
    Filed: August 26, 2003
    Publication date: May 13, 2004
    Inventors: Michael Harter, Michael G. Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
  • Side-chain halogenated amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases
    Publication number: 20040082658
    Abstract: The invention relates to COOH compounds of formula (I), to a method for their production and to the use thereof as medicaments.
    Type: Application
    Filed: August 26, 2003
    Publication date: April 29, 2004
    Inventors: Michael Harter, Michael Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder