Abstract: The present invention relates to a method for reducing polysorbate degradation by low amounts of citric acid in a protein formulation and a protein formulation with low amounts of citric acid having reduced polysorbate degradation.

Abstract: A granular catalyst may be used for hydrolyzing amino nitriles and/or amino amides to amino acids or derivatives thereof. A process for preparing such a catalyst and a method for preparing an amino acid or derivative thereof may include contacting a solution or suspension including an amino nitrile and/or an amino amide with water in the presence of such a catalyst or in the presence of a catalyst obtained by such a process.

Abstract: An ultrashort-pulse compressor includes (a) one or more bulk-optics intersecting a propagation path of an ultrashort-pulsed laser beam multiple times to spectrally broaden a pulse of the laser beam during each of multiple passes through the bulk-optic(s), (b) one or more dispersive optics for compressing a duration of the pulse after each of the multiple passes, and (c) a plurality of focusing elements for focusing the laser beam between the multiple passes. Propagation distances between the bulk-optic(s) and the focusing elements are detuned from imaging such that a spot size of the laser beam, at the bulk-optic(s), is greater at each successive one of the multiple passes. As the laser beam propagates through this compressor, each laser pulse is alternatingly spectral broadened and temporally compressed. The increasing spot size of the laser, for each pass, helps prevent optical damage, run-away self-focusing, and other undesirable outcomes.

Abstract: A method is for inserting a further data block into a first ledger, the first ledger including data blocks. In an embodiment, the method includes receiving a further medical dataset via an interface; determining the further data block via a calculation unit. The further data block includes the further medical dataset and a further link information. The further link information includes a hash of at least one of the data blocks of the first ledger. Finally, in an embodiment the method includes inserting the further data block into the first ledger via the calculation unit.

Abstract: A method, system, and computer program product for predictive maintenance. A method may include receiving operation data associated with one or more injection systems, wherein the operation data includes one or more operation parameters associated with one or more operations of the one or more injection systems: determining one or more prediction scores for the one or more injection systems based on the operation data, wherein the one or more prediction scores include one or more predictions of one or more operation failures or misuses for the one or more injection systems; and providing maintenance data associated with the one or more operation failures or misuses, wherein the maintenance data is based on the one or more prediction scores.

Abstract: The present teachings relate to a method for improving a production process for manufacturing a chemical product at an industrial plant comprising at least one equipment and one or more computing units, and the product being manufactured by processing at least one input material, which method comprises: providing at least one desired performance parameter related to the chemical product, determining a set of control settings for controlling the production of the chemical product: wherein the control settings are determined using a scorer module configured to select at least one historical object identifier from a memory storage, wherein the historical object identifier has appended to it historical process parameters and/or operational settings that were used for manufacturing past one or more chemical products. The present teachings also relate to a system for improving the production process, a use and a software program.

Abstract: A visualisation system for visualising the processing of a chemical product uses at least two processing units. The visualisation system contains a communication interface, a profiling module, and a user interface. The communication interface is configured for communicating with the processing units to receive a respective value of processing parameters for processing the chemical product. The profiling module is configured for providing a reference profile including a respective reference value for processing parameters for a reference chemical product and for providing a profile for the chemical product. The profile includes a respective deviation value of processing parameters for the chemical product determined based on a difference between the respective value of the processing parameters for processing the chemical product and the respective reference value.

Abstract: The present teachings relate to a method for improving a production process for manufacturing a chemical product using at least one input material at an industrial plant, the industrial plant comprising a plurality of physically separated equipment zones, the method comprising: providing, via an interface, an upstream object identifier comprising input material data; receiving, at a computing unit, real-time process data from one or more of the equipment zones; determining, via the computing unit, a subset of the real-time process data based on the upstream object identifier and a zone presence signal; computing, via the computing unit, at least one zone-specific performance parameter of the chemical product related to the upstream object identifier based on the subset of the real-time process data and historical data; determining, in response to at least one of the performance parameters, a target equipment zone where the input material and/or chemical product is to be sent.

Abstract: The present teachings relate to a method for monitoring a production process for manufacturing a chemical product at an industrial plant, the method comprising: providing an up-stream object identifier comprising input material data, receiving real-time process data from one or more of the equipment zones; determining a subset of the real-time process data based on the upstream object identifier and a zone presence signal; computing at least one zone-specific performance parameter of the chemical product related to the up-stream object identifier based on the subset of the real-time process data and historical data; appending, to the upstream object identifier, the at least one zone-specific performance parameter. The present teachings also relate to a system for monitoring a production process, a dataset, use, a method for generating the dataset and a software program for the same.

Abstract: A method can be used for controlling a downstream production process for manufacturing an article at a downstream industrial plant, by processing at least one thermoplastic polyurethane (“TPU”) and/or expanded thermoplastic polyurethane (“ETPU”) material using the downstream production process. The method involves providing, at a downstream computing unit, a set of downstream control settings for controlling the production of the article. The downstream control settings are determined based on a downstream object identifier; at least one desired downstream performance parameter related to the article; and downstream historical data. The set of downstream control settings is usable for manufacturing the article at the downstream industrial plant. A corresponding system for downstream production, use, and software product are provided.

Abstract: A suction nozzle (23) for a hollow jet suction box (14) is used for sucking liquid jets (4). The jet suction box has on a box casing (18) at least one slot casing opening (20) to a box interior space (17). The suction nozzle (23, 23?) has a nozzle body (24), arrangeable above the casing opening (20), with a slot suction opening (25), which passes through the nozzle body in a flow direction (23?). The suction opening extends from an inlet side (26) at a free end to an outlet side (27), arrangeable at the casing opening. The nozzle body has a mobile sealing element (29, 29?) adjacent the suction opening and laterally defining the slot-like suction opening and a resilient expansion device (33), which acts on the sealing element (29, 29?) and pushes the sealing element outward, away from the outlet side, against the suction flow direction.

Abstract: The present teachings relate to a method for improving a production process for manufacturing a chemical product at an industrial plant comprising at least one equipment and one or more computing units, and the product being manufactured by processing at least one input material, which method comprises: receiving real-time process data from the equipment; determining a subset of the real-time process data; computing at least one state related to the input material and/or the equipment. The present teachings also relate to a system for improving the production process, a use, and a software program.

Abstract: A method for assessing the state of damage of a semiconductor module that is subject to operational loading, in particular a semiconductor module of a drive system converter, that includes at least one semiconductor component arranged on or in a support structure. It is possible not only to estimate a spent service life for the entire semiconductor module, but also to detect unexpected or undesirable loading states and thus a premature reduction of the remaining service life of the semiconductor module. Continuous load assessments are thus possible already during the operation of the semiconductor module and allow interventions to be made in good time.

Abstract: The present teachings relate to a method for monitoring and/or controlling a production process for manufacturing at least one industrial product at an industrial plant comprising at least one equipment by processing at least one input, the method comprising: receiving, via an input inter-face, real-time process data from the equipment; determining, via the computing unit, a subset of the real-time process data; providing as output data the subset of the real-time process data. The present teachings also relate to a system, a use, and a software product.

Abstract: Described herein is a two-part condensation curable adhesive composition suitable for adhering a front lens having an inner surface coated with an anti-haze coating to a lamp body to create a sealed lamp unit. In general, once cured in place, residual ingredients from the adhesive composition or by-products of cure reactions thereof do not visibly inhibit functionality of the anti-haze coating of the sealed lamp unit.

Abstract: The present teachings relate to a method for digitally tracking a chemical product manufactured at an industrial plant comprising at least one equipment; and, the product being manufactured by processing, via the equipment, at least one input material using a production process, which method comprises: providing, via an interface, an object identifier comprising input material data; wherein the input material data is indicative of one or more property of the input material, receiving, via the interface, process data from the equipment; the process data being indicative of the process parameters and/or equipment operating conditions that the input material is processed under, appending, to the object identifier, at least a part of the process data. The present teachings also relate to a system for digitally tracking a chemical product and a software product.

Abstract: The present teachings relate to a method for controlling a production process, for manufacturing a chemical product, comprising: providing an upstream object identifier comprising input material data and at least one desired performance parameter related to the chemical product; determining a set of process and/or operation parameters based on the upstream object identifier and the at least one desired performance parameter; determining zone-specific control settings for each of the equipment zones based on the determined set of process and/or operation parameters and historical data; providing the zone-specific control settings for controlling the production of the chemical product related to the upstream object identifier. The present teachings also relate to a system for controlling a production process, a use of the control settings, and a software product for implementing the method steps disclosed herein.

Abstract: The present teachings relate to a method for controlling a downstream production process for manufacturing a chemical product using at least one precursor material, the method comprising: providing a set of downstream control settings for controlling the production of the chemical product, wherein the downstream control settings are determined based on: a downstream object identifier; the downstream object identifier comprising precursor data; at least one desired downstream performance parameter related to the chemical product; downstream historical data; and wherein the set of downstream control settings is usable for manufacturing the chemical product at the downstream industrial plant. The present teachings also relate to a system, a use and a software product.

Abstract: A telephoto lens having an entrance pupil of between 80 and 110 mm includes a lens head and a focusing component. The lens head, as a first optical assembly, consists of four lens elements with a refractive power sequence that alternates in the light direction. The focusing component is a second optical assembly made of at least two lens elements and has a relative aperture of between 1:4.5 and 1:7.

Abstract: A method and system perform quantum-assisted finite elements-based, design optimization of an object to minimize a shape-specific quantity by manipulating the shape of the object using a processing unit, for example, a Quantum Processing Unit (QPU). As a result, a shape-specific quantity, such as an approximation of sound pressure at a specific position around an object, can be minimized by manipulating the object shape using the QPU.