Patents by Inventor Michael Howell

Michael Howell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12233067
    Abstract: The present disclosure relates to topical treatment of vitiligo using ruxolitinib, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 8, 2022
    Date of Patent: February 25, 2025
    Assignee: Incyte Corporation
    Inventors: Kathleen Butler, Jim Lee, Kang Sun, Fiona Kuo, Michael Howell
  • Publication number: 20240417399
    Abstract: Disclosed herein are small molecule aryl hydrocarbon receptor (AhR) modulator compositions, pharmaceutical compositions, the use and preparation thereof.
    Type: Application
    Filed: October 13, 2022
    Publication date: December 19, 2024
    Inventors: Michael Howell, Steven Bruce Cohen, Elizabeth Paige Stout, Venkata Rami Reddy Macherla, Phil S. Baran, Eduardo Esquenazi, Tamara Schwent, Farhana Barmare
  • Publication number: 20240417400
    Abstract: The present application is directed towards the provision of compounds of formula I, pharmaceutical compositions and methods of treatment thereof. Also disclosed are methods of treating a disease comprising the compounds of formula II. The compounds of the invention are modulators of aryl hydrocarbon receptor (AhR) and find use in the treatment of dermatologic, respiratory, oncologic, autoimmune or immunologic disease.
    Type: Application
    Filed: October 13, 2022
    Publication date: December 19, 2024
    Inventors: Michael Howell, Steven Bruce Cohen, Elizabeth Paige Stout, Venkata Rami Reddy Macherla, Phil S. Baran, Eduardo Esquenazi, Tamara Schwent
  • Publication number: 20240409648
    Abstract: The present invention relates to anti-IL-36R binding compounds, in particular new anti-IL-36R antibodies and therapeutic and diagnostic methods and compositions for using the same.
    Type: Application
    Filed: August 27, 2024
    Publication date: December 12, 2024
    Inventors: Su-Ellen BROWN, Keith CANADA, Lukasz CHLEWICKI, Michael HOWELL, Detlev MENNERICH, Joseph Robert WOSKA, JR.
  • Publication number: 20240347148
    Abstract: A client device presents a user interface including a macro entry field for defining a macro indicator from a plurality of macro indicators and transmits the macro indicator. A server stores a database of macro-based diagnoses, each macro-based diagnosis associated with one or more elements of an accession, and one or more specimens associated with the accession. The server also receives the macro indicator from the client device, retrieves an initial diagnosis from the database of macro-based diagnoses responsive to the macro indicator, and transmits the initial diagnosis. The client device, receives the initial diagnosis, pre-populates one or more text boxes on the user interface with information from the initial diagnosis, and enables the user to edit the pre-populated one or more text boxes.
    Type: Application
    Filed: June 24, 2024
    Publication date: October 17, 2024
    Inventors: Gregg LAHTI, Matthew HOPPES, Michael HOWELL, Brandon SLEATER
  • Patent number: 12020784
    Abstract: A client device presents a user interface including a macro entry field for defining a macro indicator from a plurality of macro indicators and transmits the macro indicator. A server stores a database of macro-based diagnoses, each macro-based diagnosis associated with one or more elements of an accession, and one or more specimens associated with the accession. The server also receives the macro indicator from the client device, retrieves an initial diagnosis from the database of macro-based diagnoses responsive to the macro indicator, and transmits the initial diagnosis. The client device, receives the initial diagnosis, pre-populates one or more text boxes on the user interface with information from the initial diagnosis, and enables the user to edit the pre-populated one or more text boxes.
    Type: Grant
    Filed: March 15, 2023
    Date of Patent: June 25, 2024
    Assignee: Cerebrum Holding Corporation
    Inventors: Gregg Lahti, Matthew Hoppes, Michael Howell, Brandon Sleater
  • Publication number: 20240191309
    Abstract: Described herein are methods, systems, and compositions for non-invasively diagnosing or detecting a skin disease or disorder. Diagnosing or detecting a non-melanoma skin cancer (e.g., squamous cell carcinoma or basal cell carcinoma) as provided herein comprises detecting and/or comparing gene expression levels of identified genes. Methods, systems, and compositions are also described for differentiation of non-melanoma skin cancer (NMSC) from other diseases, such as actinic keratosis (AK).
    Type: Application
    Filed: April 12, 2022
    Publication date: June 13, 2024
    Inventors: John William WHITAKER, Michael HOWELL, Rizi AI, James ROCK, Loren CLARKE, Lien Thi VO, Emad BAHRAMI SAMANI, John Daniel DOBAK, III, Jordan MCGHEE, Zuxu YAO
  • Publication number: 20240167102
    Abstract: Disclosed herein are methods of assessing response to therapies. Also described herein are methods for using the methods described herein for assessing response to therapies for treating skin diseases or skin conditions.
    Type: Application
    Filed: March 1, 2022
    Publication date: May 23, 2024
    Inventors: Michael HOWELL, Zuxu YAO, James ROCK, Burkhard JANSEN
  • Patent number: 11972845
    Abstract: A client device presents a user interface including a macro entry field for defining a macro indicator from a plurality of macro indicators and transmits the macro indicator. A server stores a database of macro-based diagnoses, each macro-based diagnosis associated with one or more elements of an accession, and one or more specimens associated with the accession. The server also receives the macro indicator from the client device, retrieves an initial diagnosis from the database of macro-based diagnoses responsive to the macro indicator, and transmits the initial diagnosis. The client device, receives the initial diagnosis, pre-populates one or more text boxes on the user interface with information from the initial diagnosis, and enables the user to edit the pre-populated one or more text boxes.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: April 30, 2024
    Assignee: Cerebrum Holding Corporation
    Inventors: Gregg Lahti, Matthew Hoppes, Michael Howell, Brandon Sleater
  • Patent number: 11935631
    Abstract: A client device presents a user interface including a macro entry field for defining a macro indicator from a plurality of macro indicators and transmits the macro indicator. A server stores a database of macro-based diagnoses, each macro-based diagnosis associated with one or more elements of an accession, and one or more specimens associated with the accession. The server also receives the macro indicator from the client device, retrieves an initial diagnosis from the database of macro-based diagnoses responsive to the macro indicator, and transmits the initial diagnosis. The client device, receives the initial diagnosis, pre-populates one or more text boxes on the user interface with information from the initial diagnosis, and enables the user to edit the pre-populated one or more text boxes.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: March 19, 2024
    Assignee: Cerebrum Holding Corporation
    Inventors: Gregg Lahti, Matthew Hoppes, Michael Howell, Brandon Sleater
  • Publication number: 20230364095
    Abstract: The present disclosure relates to topical treatment of vitiligo using ruxolitinib, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 16, 2021
    Publication date: November 16, 2023
    Applicant: INCYTE CORPORATION
    Inventors: Kathleen BUTLER, Jim LEE, Kang SUN, Fiona KUO, Michael HOWELL
  • Publication number: 20230355628
    Abstract: The present disclosure relates to topical treatment of vitiligo using ruxolitinib, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 8, 2022
    Publication date: November 9, 2023
    Inventors: Kathleen BUTLER, Jim LEE, Kang SUN, Fiona KUO, Michael HOWELL
  • Publication number: 20230293431
    Abstract: The present disclosure relates to topical treatment of vitiligo using ruxolitinib, or a pharmaceutically acceptable salt thereof based on results from long term clinical studies.
    Type: Application
    Filed: February 28, 2023
    Publication date: September 21, 2023
    Inventors: Kathleen BUTLER, Jim Lee, Kang SUN, Fiona KUO, Michael HOWELL
  • Publication number: 20230293528
    Abstract: This disclosure relates to methods of reducing itch in patients with atopic dermatitis and treating patients with atopic dermatitis by administering a topical 0.75% or 1.5% ruxolitinib cream two times per day.
    Type: Application
    Filed: October 28, 2022
    Publication date: September 21, 2023
    Inventors: Michael Kuligowski, Kang Sun, Michael Howell, May Grace E. Venturanza, Jim Lee
  • Publication number: 20230215522
    Abstract: A client device presents a user interface including a macro entry field for defining a macro indicator from a plurality of macro indicators and transmits the macro indicator. A server stores a database of macro-based diagnoses, each macro-based diagnosis associated with one or more elements of an accession, and one or more specimens associated with the accession. The server also receives the macro indicator from the client device, retrieves an initial diagnosis from the database of macro-based diagnoses responsive to the macro indicator, and transmits the initial diagnosis. The client device, receives the initial diagnosis, pre-populates one or more text boxes on the user interface with information from the initial diagnosis, and enables the user to edit the pre-populated one or more text boxes.
    Type: Application
    Filed: March 15, 2023
    Publication date: July 6, 2023
    Inventors: Gregg Lahti, Matthew Hoppes, Michael Howell, Brandon Sleater
  • Publication number: 20230143893
    Abstract: The present application provides a method of isolating highly purified and characterized exosomes from tissue and cellular sources for the purpose of regenerative medicine as well as a composition including an exosome or an exosomal compound or component. The composition is used for the therapeutic treatment of various physiological damages and diseases, including skin or cutaneous damages/diseases, cardiovascular diseases, ophthalmic diseases, neurological diseases, viral diseases, and cancer among other damages and diseases.
    Type: Application
    Filed: March 23, 2021
    Publication date: May 11, 2023
    Inventors: Travis H. Bird, Tammy Luttrell, Michael Howell, Samantha Rosenberry
  • Patent number: 11602536
    Abstract: The present disclosure relates to topical treatment of vitiligo using ruxolitinib, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: March 14, 2023
    Assignee: Incyte Corporation
    Inventors: Kathleen Butler, Jim Lee, Kang Sun, Fiona Kuo, Michael Howell
  • Patent number: 11590138
    Abstract: The present disclosure relates to topical treatment of vitiligo using ruxolitinib, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 8, 2022
    Date of Patent: February 28, 2023
    Assignee: Incyte Corporation
    Inventors: Kathleen Butler, Jim Lee, Kang Sun, Fiona Kuo, Michael Howell
  • Patent number: 11590137
    Abstract: This disclosure relates to methods of reducing itch in patients with atopic dermatitis and treating patients with atopic dermatitis by administering a topical 0.75% or 1.5% ruxolitinib cream two times per day.
    Type: Grant
    Filed: March 28, 2022
    Date of Patent: February 28, 2023
    Assignee: Incyte Corporation
    Inventors: Michael Kuligowski, Kang Sun, Michael Howell, May Grace E. Venturanza, Jim Lee
  • Patent number: D1007323
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: December 12, 2023
    Assignee: WD-40 MANUFACTURING COMPANY
    Inventors: Jeffrey T. Cole, Christopher Michael Howell, John W. Freudenberg, Ryan Paul Davidson, Michael J. Starzman, Joseph G. Peschke, Paul Mierzwa