Patents by Inventor Michael J. Hawkins

Michael J. Hawkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphonic acid compounds as inhibitors of serine proteases
    Patent number: 7459461
    Abstract: The present invention is directed to phosphonic acid compounds useful as serine protease inhibitors, compositions thereof and methods for treating inflammatory and serine protease mediated disorders.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: December 2, 2008
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Michael N. Greco, Harold R. Almond, Lawrence de Garavilla, Michael J. Hawkins, Michael J. Humora, Yun Qian, Donald Gilmore Walker, Sergio Cesco-Cancian, Christopher Norman Nilsen, Mitul N. Patel, Kirk Leonard Sorgi, Eugene Powell
  • Substituted heterocyclic acyl-tripeptides useful as thrombin receptor modulators
    Patent number: 7312306
    Abstract: The invention is directed to substituted heterocyclic acyl-tripeptides useful as thrombin receptor modulators, their use in wound healing and preventing platelet aggregation. Pharmaceutical compositions comprising the substituted heterocyclic acyl-tripeptides of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: December 25, 2007
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: David F. McComsey, Bruce E. Maryanoff, Michael J. Hawkins
  • Aminopyrrolidine sulfonamides as serine protease inhibitors
    Patent number: 6890939
    Abstract: The present invention is directed to compounds useful as selective serine protease or dual-serine protease inhibitors, compositions thereof and methods for treating serine protease or dual-serine protease mediated disorders.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: May 10, 2005
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Michael N. Greco, Bruce E. Maryanoff, Michael J. Hawkins, Robert E. Boyd
  • Substituted heterocyclic acyl-tripeptides useful as thrombin receptor modulators
    Patent number: 6747127
    Abstract: The invention is directed to substituted heterocyclic acyl-tripeptides useful as thrombin receptor modulators, their use in wound healing and preventing platelet aggregation. Pharmaceutical compositions comprising the substituted heterocyclic acyl-tripeptides of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: June 8, 2004
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: David F. McComsey, Bruce E. Maryanoff, Michael J. Hawkins
  • Novel phosphonic acid compounds as inhibitors of serine proteases
    Publication number: 20040082544
    Abstract: The present invention is directed to phosphonic acid compounds useful as serine protease inhibitors, compositions thereof and methods for treating inflammatory and serine protease mediated disorders.
    Type: Application
    Filed: April 16, 2003
    Publication date: April 29, 2004
    Inventors: Michael N. Greco, Harold R. Almond, Lawrence de Garavilla, Michael J. Hawkins, Michael J. Humora, Yun Qian, Donald Gilmore Walker, Sergio Cesco-Cancian, Christopher Norman Nilsen, Mitul N. Patel, Kirk Leonard Sorgi, Eugene Powell
  • Substituted heterocyclic acyl-tripeptides useful as thrombin receptor modulators
    Publication number: 20040063903
    Abstract: The invention is directed to substituted heterocyclic acyl-tripeptides useful as thrombin receptor modulators, their use in wound healing and preventing platelet aggregation. Pharmaceutical compositions comprising the substituted heterocyclic acyl-tripeptides of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.
    Type: Application
    Filed: June 26, 2003
    Publication date: April 1, 2004
    Inventors: David F. McComsey, Bruce E. Maryanoff, Michael J. Hawkins
  • Aminopyrrolidine sulfonamides as serine protease inhibitors
    Patent number: 6710061
    Abstract: The present invention is directed to compounds useful as selective serine protease or dual-serine protease inhibitors, compositions thereof and methods for treating serine protease or dual-serine protease mediated disorders.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: March 23, 2004
    Assignee: Ortho-McNeil Pharamceutical, Inc.
    Inventors: Michael N. Greco, Bruce E. Maryanoff, Michael J. Hawkins, Robert E. Boyd
  • Aminopyrrolidine sulfonamides as serine protease inhibitors
    Publication number: 20030203936
    Abstract: The present invention is directed to compounds useful as selective serine protease or dual-serine protease inhibitors, compositions thereof and methods for treating serine protease or dual-serine protease mediated disorders.
    Type: Application
    Filed: May 16, 2003
    Publication date: October 30, 2003
    Inventors: Michael N. Greco, Bruce E. Maryanoff, Michael J. Hawkins, Robert E. Boyd
  • Novel phosphonic acid compounds as inhibitors of serine proteases
    Publication number: 20030195172
    Abstract: The present invention is directed to phosphonic acid compounds useful as serine protease inhibitors, compositions thereof and methods for treating inflammatory and serine protease mediated disorders.
    Type: Application
    Filed: October 17, 2002
    Publication date: October 16, 2003
    Inventors: Michael N. Greco, Harold R. Almond, Lawrence de Garavilla, Michael J. Hawkins, Michael J. Humora, Yun Qian, Donald Gilmore Walker, Sergio Cesco-Cancian, Christopher Norman Nilsen, Mitul N. Patel
  • Aminopyrrolidine sulfonamides as serine protease inhibitors
    Patent number: 6630505
    Abstract: The present invention is directed to compounds useful as selective serine protease or dual-serine protease inhibitors, compositions thereof and methods for treating serine protease or dual-serine protease mediated disorders.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: October 7, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Michael N. Greco, Bruce E. Maryanoff, Michael J. Hawkins, Robert E. Boyd
  • AMINOPYRROLIDINE SULFONAMIDES AS SERINE PROTEASE INHIBITORS
    Publication number: 20030166680
    Abstract: The present invention is directed to compounds useful as selective serine protease or dual-serine protease inhibitors, compositions thereof and methods for treating serine protease or dual-serine protease mediated disorders.
    Type: Application
    Filed: November 25, 2002
    Publication date: September 4, 2003
    Inventors: Michael N. Greco, Bruce E. Maryanoff, Michael J. Hawkins, Robert E. Boyd
  • Aminopyrrolidine sulfonamides as serine protease inhibitors
    Publication number: 20030166681
    Abstract: The present invention is directed to compounds useful as selective serine protease or dual-serine protease inhibitors, compositions thereof and methods for treating serine protease or dual-serine protease mediated disorders.
    Type: Application
    Filed: November 25, 2002
    Publication date: September 4, 2003
    Inventors: Michael N. Greco, Bruce E. Maryanoff, Michael J. Hawkins, Robert E. Boyd
  • Aminopyrrolidine sulfonamides as serine protease inhibitors
    Patent number: 6538017
    Abstract: The present invention is directed to compounds useful as selective serine protease or dual-serine protease inhibitors, compositions thereof and methods for treating serine protease or dual-serine protease mediated disorders.
    Type: Grant
    Filed: March 5, 2002
    Date of Patent: March 25, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Michael N. Greco, Bruce E. Maryanoff, Michael J. Hawkins, Robert E. Boyd
  • Aminopyrrolidine sulfonamides as serine protease inhibitors
    Publication number: 20030004186
    Abstract: The present invention is directed to compounds useful as selective serine protease or dual-serine protease inhibitors, compositions thereof and methods for treating serine protease or dual-serine protease mediated disorders.
    Type: Application
    Filed: March 5, 2002
    Publication date: January 2, 2003
    Inventors: Michael N. Greco, Bruce E. Maryanoff, Michael J. Hawkins, Robert E. Boyd
  • Shelf-stable rice products and processes for their production
    Patent number: 5312639
    Abstract: A process for preparing a preserved rice product is disclosed. Here rice is treated at a pH of 4.5 or below with a polymeric acid food acceptable acid and placed in a microorganism-impermeable container.
    Type: Grant
    Filed: June 5, 1991
    Date of Patent: May 17, 1994
    Assignee: Mars Incorporated
    Inventors: John G. Howard, John Atherton, Eric S. Field, Michael J. Hawkins
  • Shelf-stable rice products
    Patent number: 5308632
    Abstract: A stable rice product is disclosed which is acid-pasteurized. The rice is treated with a polymeric food acceptable acid to a pH of 4.5 and lacks an acid flavor. Alginic acid, pectic acid, carageenic acid and carboxymethylcellulose acid are indicated to be suitable acids.
    Type: Grant
    Filed: August 10, 1992
    Date of Patent: May 3, 1994
    Assignee: Mars Incorporated
    Inventors: John G. Howard, John Atherton, Eric S. Field, Michael J. Hawkins
  • Removable side molding to protect the side of a vehicle
    Patent number: 5184857
    Abstract: The present invention is a removable side bumper which is designed to be placed on the vehicle in a removable fashion when the vehicle is parked so that the vehicle is protected when people in neighboring vehicles open their doors. The present invention provides a shielding, by means of cushioned segments with an inner core tubing for support and a foam outer tubing for a cushioning, connected by a flexible cord which anchors to the wheel wells or the door wells of a vehicle and will prevent the side of the vehicle from being scratched or dented.
    Type: Grant
    Filed: May 7, 1992
    Date of Patent: February 9, 1993
    Inventor: Michael J. Hawkins