Abstract: Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.

Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.

Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.

Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Abstract: Dye labeled imidazonaphthyridine, imidazopyridine and imidazoquinoline compounds having immune response modulating activity are disclosed. The compounds are useful, inter alia, for determining the binding and/or receptor sites of the molecules.

Abstract: Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.

Abstract: Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.

Abstract: Dye labeled imidazonaphthyridine, imidazopyridine and imidazoquinoline compounds having immune response modulating activity are disclosed. The compounds are useful, inter alia, for determining the binding and/or receptor sites of the molecules.

Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain sulfonamide or sulfonamide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Abstract: Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.

Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.

Abstract: Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.

Abstract: A method of mixing colorants to achieve a target color includes combining individual colorants, detecting an output color of the combined colorants with a color sensing device and automatically adjusting the output color based on comparison between the detected output color and the target color. An apparatus for mixing colorants according to this method is also disclosed.

Abstract: An image quality control apparatus controls quality of xerographic images formed by a xerographic imaging system onto a recording medium when at least one sensor which is operative to provide signals to the xerographic imaging system for quality control malfunctions. The image quality control apparatus includes a controller device in communication with the xerographic imaging system. The controller includes a data collection device, a determining device and an input generating device. The data collection device collects and processes sensor data received from the at least one sensor while the at least one sensor is operative. The determining device determines whether the at least one sensor malfunctions.

Abstract: The present invention comprises a cap assembly that includes a cap with a single annular lug that has a retaining surface and an annular flange attachable to the cap by contact with the retaining surface.

Abstract: The present invention is a tamper evident container sealing system for sealing a cap to a container. The system includes a shrink band, shrinkable at a shrink temperature, positioned about the cap and container circumferentially, a colorant bonded to the shrink band and an adhesive bonded to the colorant. The adhesive is thermally activatable at the shrink temperature. The adhesive is in contact with the container.

Abstract: A multiple compartment package for use in the packaging of foodstuff articles includes a first compartment portion, a second compartment portion, and a retaining mechanism for retaining the first compartment portion in close relation to the second compartment portion.

Abstract: A drawing game board for non-competitive, socialized activity, has a base provided with a substantially flat upper surface for supporting drawing paper. Borders on the base extend upwardly from the upper surface thereof and define a paper location area. Within the border is a frame having a substantially rectangular shape provided by side sections and end sections. The frame has an upper surface and a lower surface. The lower surface of the frame is adapted to contact the drawing paper when the frame is moved downwardly within the border to hold the paper in place on the flat upper surface of the base. The frame is configured to provide a substantially rectangular drawing opening having a longitudinal dimension and a lateral dimension and is bordered by the side and end sections. A plurality of substantially rectangular shutters are placed between the side sections of the frame.

Abstract: An easy-open, spiral wound container for packaging refrigerated dough products includes a spirally wound fibrous core layer, forming an unbonded spiral butt joint. The container also includes an inner liner layer and an outer label layer, each having a seam. The outer label layer is weakened along the butt joint to facilitate opening of the container. An end closure member seals an end of the container.

Abstract: An easy-open, spiral wound container for packaging refrigerated dough products includes a spirally wound fibrous core layer, forming an unbonded spiral butt joint. The container also includes an inner liner layer and an outer label layer, each having a seam. The outer label layer is weakened along the butt joint to facilitate opening of the container. An end closure member seals an end of the container.