Abstract: Provided herein are low impurity compositions comprising a compound represented by Formula (I): which are useful in the treatment of disorders related to the activity of the c-KIT and PDGFR? kinases, and oncogenic forms thereof.

Abstract: Provided herein are low impurity compositions comprising a compound represented by Formula (I): which are useful in the treatment of disorders related to the activity of the c-KIT and PDGFR? kinases, and oncogenic forms thereof.

Abstract: Provided herein are low impurity compositions comprising a compound represented by Formula (I): which are useful in the treatment of disorders related to the activity of the c-KIT and PDGFR? kinases, and oncogenic forms thereof.

Abstract: A system for an attraction includes a sensor configured to capture imagery of a real world environment and a control system communicatively coupled to the sensor. The control system is configured to receive the imagery captured by the sensor, identify a real world element of the imagery, generate image data that includes a virtual element that corresponds to the real world element, and transmit the image data for presentation in the attraction.

Abstract: A device for detecting freshness of a perishable item is provided. The device includes at least one sensor for detecting an analyte of interest in the perishable item. The device further includes an integrated circuit for converting information detected by the sensor into a signal. The device also includes an antenna portion for receiving and transmitting the signal from the integrated circuit. The at least one sensor, integrated circuit and antenna portion are printed on a single sheet such that the device is unitary.

Abstract: An autonomous vehicle locker comprises a controller including a memory storing instructions and a processor configured to execute the instructions. The instructions are configured to cause the controller to associate an autonomous vehicle locker with a guest at a first location, receive an indication that guest items are within a storage compartment, secure the storage compartment based on the indication, instruct the autonomous vehicle locker to travel to a second location, identify the guest from a plurality of guests at the second location, and instruct the autonomous vehicle locker to unlock the storage compartment in response to identifying the guest.

Abstract: A variable effect activation system includes one or more sensors that generate data. The data can be assessed to determine if the data is indicative of a valid input to an interactive effect. Valid inputs may be assessed based on a lenient or relatively non-stringent threshold to permit a wide variety of guest actions to be considered valid inputs. While many of these guest actions may not be recognized as part of preprogrammed interactions with an interactive environment, the system nonetheless assesses characteristics of these inputs to provide an appropriate response, e.g., via activation of an interactive effect in a manner that aligns with the characteristics.

Abstract: An interactive portrait system includes a camera configured to capture imagery of an environment and a controller. The controller is configured to analyze the imagery to identify a guest in the environment, instruct an output device to provide an initial output to attempt to interact with the guest, and analyze the imagery to identify a behavior of the guest during the initial output, after the initial output, or both. The controller is also configured to evaluate the behavior of the guest using one or more artificial intelligence algorithms to determine whether the guest responded to the initial output. The controller is further configured to, in response to determining that the guest responded to the initial output, instruct the output device to provide an additional output to continue to attempt to interact with the guest.

Abstract: A delivery system may include one or more processors and memory storing instructions executable by the one or more processors to cause the one or more processors to identify one or more attributes of a user in one or more images and associate the one or more attributes of the user with an order placed by the user. The delivery system may also track the one or more attributes of the user in the one or more images over time to identify movement of the user within an environment and in response to the one or more attributes of the user in the one or more images remaining at a location for more than a threshold time, create an association between the one or more attributes of the user and the location. The delivery system may then provide an instruction to deliver items in the order to the location.

Abstract: Systems and methods presented herein include one or more guest activity recognition devices configured to recognize activity of one or more guests within a physical environment of an amusement park. The system also includes one or more ride vehicles of a ride of the amusement park, each ride vehicle including an artificial intelligence entity management system configured to maintain one or more ride vehicle artificial intelligence entities of the ride vehicle based at least in part on the recognized activity of the one or more guests; and one or more features disposed on the ride vehicle and configured to be activated by the artificial intelligence entity management system to simulate the existence of the one or more ride vehicle artificial intelligence entities in accordance with one or more properties of the one or more ride vehicle artificial intelligence entities.

Abstract: Techniques for remote monitoring of a patient and corresponding medical device(s) are described. The remote monitoring comprises providing an interactive session configured to allow a user to navigate a plurality of subsessions, determining a first set of data items in accordance with a first subsession, the first set of data items including the image data, determining a second set of data items in accordance with a second subs ession of the interactive session, determining, based at least in part on the first set of data items and the second set of data items, an abnormality, and outputting a post-implant report of the interactive session.

Abstract: An interactive system for an amusement park attraction includes one or more processors configured to identify a non-fungible token (NFT) possessed by a user within the amusement park attraction. The one or more processors are also configured to transform the NFT into a derivative of the NFT based on context data for the amusement park attraction. The one or more processors are further configured to instruct display of the derivative of the NFT on a display screen within the amusement park attraction.

Abstract: An interactive system includes one or more processors and memory storing instructions executable by the one or more processors to cause the one or more processors to identify one or more non-fungible tokens (NFTs) possessed by a user and to provide control signals to one or more output devices of a portable object based on the one or more NFTs. The one or more output devices include an actuator configured to drive movement of at least a portion of the portable object, a speaker configured to output sounds, a light emitter configured to emit light, or any combination thereof.

Abstract: A ride system may include a ride vehicle that supports a passenger and an attention tracker to determine a current direction of attention of the passenger. The ride system may also include a control system for maintaining an environment of the passenger. Maintaining the environment may include determining a set of content to be incorporated into the environment based at least in part on the current direction of attention.

Abstract: The present invention relates to compounds of Formula I that function as inhibitors of RET (rearranged during transfection) kinase enzyme activity: wherein HET, bonds a, b, c and d, X1, X2, X3, X4, R2, and R3 are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which RET kinase activity is implicated.

Abstract: A variable effect activation system includes one or more sensors that generate data. The data can be assessed to determine if the data is indicative of a valid input to an interactive effect. Valid inputs may be assessed based on a lenient or relatively non-stringent threshold to permit a wide variety of guest actions to be considered valid inputs. While many of these guest actions may not be recognized as part of preprogrammed interactions with an interactive environment, the system nonetheless assesses characteristics of these inputs to provide an appropriate response, e.g., via activation of an interactive effect in a manner that aligns with the characteristics.

Abstract: Systems and methods presented herein include ride vehicles configured to locally store player state caches. For example, ride vehicles may include an on-board ride and game control sub-system configured to control local features of a ride and game control system associated with an amusement park ride system (e.g., that occur locally on the ride vehicles), to locally cache player state data for riders of the ride vehicles during ride cycles of the ride vehicles, and to synchronize the locally-cached player state data with global player state data maintained by an off-board ride and game control sub-system after the ride cycles of the ride vehicles.

Abstract: A device for detecting freshness of a perishable item is provided. The device includes at least one sensor for detecting an analyte of interest in the perishable item. The device further includes an integrated circuit for converting information detected by the sensor into a signal. The device also includes an antenna portion for receiving and transmitting the signal from the integrated circuit. The at least one sensor, integrated circuit and antenna portion are printed on a single sheet such that the device is unitary.

Abstract: A system includes a gimbal, a shotgun microphone coupled to the gimbal, a camera, and at least one processor. The at least one processor is configured to receive data indicative of an image or video feed from the camera. The at least one processor is also configured to determine, based on the data indicative of the image or video feed, a primary human speaker among a group of humans and a location of the primary human speaker. The at least one processor is also configured to control the gimbal to point the shotgun microphone at the location of the primary human speaker.

Abstract: A device for detecting freshness of a perishable item is provided. The device includes at least one sensor for detecting an analyte of interest in the perishable item. The device further includes an integrated circuit for converting information detected by the sensor into a signal. The device also includes an antenna portion for receiving and transmitting the signal from the integrated circuit. The at least one sensor, integrated circuit and antenna portion are printed on a single sheet such that the device is unitary.