Abstract: Compounds of formula (I), formula (I), processes for their production and their use as pharmaceuticals.

Abstract: The invention provides a chemical entity of Formula (I), and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies, detection and imaging techniques, and radioactive treatments; and therapies, including inhibiting PDE4, enhancing neuronal plasticity, treating neurological disorders, providing neuroprotection, treating a cognitive impairment associated with a CNS disorder, enhancing the efficiency of cognitive and motor training, providing neurorecovery and neurorehabilitation, enhancing the efficiency of non-human animal training protocols, and treating treating peripheral disorders, including inflammatory and renal disorders.

Abstract: Various aspects of the subject technology relate to systems, methods, and machine-readable media for bridging native tokens. Various aspects may include initializing a first blockchain by allocating a plurality of native tokens. Aspects may also include transferring, using a bridge, one or more transactions from a second blockchain to the first blockchain using locked tokens on the second blockchain as collateral. Aspects may also include minting new native tokens at the first blockchain when a value of transactions sum to the plurality of native tokens and the plurality of native tokens are backed by the locked tokens. Aspects may also include reporting, to the second blockchain, the amount of tokens used for the transaction fees in the one or more transactions. Aspects may also include burning, at the second blockchain, tokens corresponding to the amount of tokens used for paying transaction fees.

Abstract: This application relates generally to aerial mycelium and methods of making aerial mycelium suitable for use as a food or textile product or ingredient. The aerial mycelium can be grown using a growth matrix provided into a growth environment and introducing aqueous mist into the growth environment. The aqueous mist has a mean mist deposition rate to allow for aerial mycelial growth from the growth matrix.

Abstract: There is set forth herein obtaining data traffic monitoring data, the data traffic monitoring data being in dependence on monitoring of traffic received by a container of a protected computing environment; obtaining data traffic monitoring data, the data traffic monitoring data being in dependence on monitoring of traffic received by a processing resource of a computing environment; obtaining a state of the processing resource and provisioning a utility processing resource to include the state of the processing resource; and configuring the computing environment to route data traffic to the utility processing resource.

Abstract: Various aspects of the subject technology relate to systems, methods, and machine-readable media for providing an application trusted execution environment. Various aspects may include performing attestation of each application enclave of a plurality of application enclaves for a plurality of applications. Aspects may also include receiving a request from a client. Aspects may also include selecting a load balancer to forward the request to the application enclaves. Aspects may also include determining a sensitivity level of the request that is associated with a secured environment parameter. Aspects may include routing, by an enclave server of the load balancer, the request to an application enclave according to the sensitivity level for execution of an application of the plurality of applications in the application trusted execution environment.

Abstract: The disclosed device is a wheelchair that is capable of being converted into a bed and visa versa. The device is also able to transfer patients from it unto another surface, such as a bed or an examination table. The device may be used as a rescue apparatus to lift patients that fell on the ground. The mobility device may additionally have hygienic openings to enable a rider to relieve him or herself without needing to be lifted or transferred off the mobility device. The device is fully motorized, with all functions capable of being performed at the touch of a button.

Abstract: A latch assembly includes a latch body having a longitudinal wall portion extending from a front wall portion to a rear hinge portion, first and second latch members assembled with the longitudinal wall portion and laterally movable between an extended position and a retracted position, and a hinge bracket. The hinge bracket defines a mounting surface and is hingedly attached to the rear hinge portion of the latch body for angular adjustment of the latch body with respect to the mounting surface. When the latch body is oriented at a first angle, first and second mounting apertures in the front wall portion align with first and second mounting apertures in the hinge bracket, such that installation of mounting fasteners through the corresponding first and second mounting apertures of the front wall portion and the hinge bracket secures the latch body at the first angle.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods that provide and apply dynamic image filters to modify digital images over time to simulate a dynamical system. Such dynamic image filters can modify a digital image to progress through different frames depicting visual effects mimicking natural and/or artificial qualities of a fluid, gas, chemical, cloud formation, fractal, or various physical matters or phenomena according to a dynamic-simulation function. Upon detecting a selection of a dynamic image filter, the disclosed systems can identify a dynamic-simulation function corresponding to the dynamical system. Based on selecting a portion of the (or entire) digital image at which to apply the dynamic image filter, the disclosed systems incrementally modify the digital image across time steps to simulate the dynamical system according to the dynamic-simulation function.

Abstract: There is set forth herein obtaining data traffic monitoring data, the data traffic monitoring data being in dependence on monitoring of traffic received by a container of a protected computing environment; obtaining data traffic monitoring data, the data traffic monitoring data being in dependence on monitoring of traffic received by a processing resource of a computing environment; obtaining a state of the processing resource and provisioning a utility processing resource to include the state of the processing resource; and configuring the computing environment to route data traffic to the utility processing resource.

Abstract: A golf club head with a face component having a polymer-microsphere mixture is disclosed herein, as are methods of making face inserts with a polymer-microsphere mixture.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods that provide and apply dynamic image filters to modify digital images over time to simulate a dynamical system. Such dynamic image filters can modify a digital image to progress through different frames depicting visual effects mimicking natural and/or artificial qualities of a fluid, gas, chemical, cloud formation, fractal, or various physical matters or phenomena according to a dynamic-simulation function. Upon detecting a selection of a dynamic image filter, the disclosed systems can identify a dynamic-simulation function corresponding to the dynamical system. Based on selecting a portion of the (or entire) digital image at which to apply the dynamic image filter, the disclosed systems incrementally modify the digital image across time steps to simulate the dynamical system according to the dynamic-simulation function.

Abstract: There is set forth herein obtaining data traffic monitoring data, the data traffic monitoring data being in dependence on monitoring of traffic received by a container of a protected computing environment; obtaining data traffic monitoring data, the data traffic monitoring data being in dependence on monitoring of traffic received by a processing resource of a computing environment; obtaining a state of the processing resource and provisioning a utility processing resource to include the state of the processing resource; and configuring the computing environment to route data traffic to the utility processing resource.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods that provide and apply dynamic image filters to modify digital images over time to simulate a dynamical system. Such dynamic image filters can modify a digital image to progress through different frames depicting visual effects mimicking natural and/or artificial qualities of a fluid, gas, chemical, cloud formation, fractal, or various physical matters or phenomena according to a dynamic-simulation function. Upon detecting a selection of a dynamic image filter, the disclosed systems can identify a dynamic-simulation function corresponding to the dynamical system. Based on selecting a portion of the (or entire) digital image at which to apply the dynamic image filter, the disclosed systems incrementally modify the digital image across time steps to simulate the dynamical system according to the dynamic-simulation function.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods that provide and apply dynamic image filters to modify digital images over time to simulate a dynamical system. Such dynamic image filters can modify a digital image to progress through different frames depicting visual effects mimicking natural and/or artificial qualities of a fluid, gas, chemical, cloud formation, fractal, or various physical matters or phenomena according to a dynamic-simulation function. Upon detecting a selection of a dynamic image filter, the disclosed systems can identify a dynamic-simulation function corresponding to the dynamical system. Based on selecting a portion of the (or entire) digital image at which to apply the dynamic image filter, the disclosed systems incrementally modify the digital image across time steps to simulate the dynamical system according to the dynamic-simulation function.

Abstract: A latch assembly includes a latch body having a longitudinal wall portion extending from a front wall portion to a rear hinge portion, first and second latch members assembled with the longitudinal wall portion and laterally movable between an extended position and a retracted position, and a hinge bracket. The hinge bracket defines a mounting surface and is hingedly attached to the rear hinge portion of the latch body for angular adjustment of the latch body with respect to the mounting surface. When the latch body is oriented at a first angle, first and second mounting apertures in the front wall portion align with first and second mounting apertures in the hinge bracket, such that installation of mounting fasteners through the corresponding first and second mounting apertures of the front wall portion and the hinge bracket secures the latch body at the first angle.

Abstract: The present disclosure is directed toward systems and methods for tracking objects in videos. For example, one or more embodiments described herein utilize various tracking methods in combination with an image search index made up of still video frames indexed from a video. One or more embodiments described herein utilize a backward and forward tracking method that is anchored by one or more key frames in order to accurately track an object through the frames of a video, even when the video is long and may include challenging conditions.

Abstract: The Learner Interaction Monitoring Systems (LiMS) is a web-based application that can interface with any web-based course delivery platform to transform the online learning environment into an active observer of learner engagement. The LiMS ‘event capture model’ collects detailed real-time data on learner behavior in self-directed online learning environments, and interprets these data by drawing on behavioral research. The LiMS offers education and training managers in corporate contexts a valuable tool for the evaluation of learner performance and course design. By allowing more detailed demonstration of ROI in education and training, LiMS allows managers to make the case for web based courseware that reflects appropriate and evidence-based instructional design, rather than budgetary constraints.

Abstract: The present disclosure is directed toward systems and methods for tracking objects in videos. For example, one or more embodiments described herein utilize various tracking methods in combination with an image search index made up of still video frames indexed from a video. One or more embodiments described herein utilize a backward and forward tracking method that is anchored by one or more key frames in order to accurately track an object through the frames of a video, even when the video is long and may include challenging conditions.