Abstract: A device and method for providing body cooling for treating fever. The cooling device applies cooling to blood flowing in a vein or artery, e.g., the vena cavae, that is then distributed throughout the body.

Abstract: Various embodiments include methods and systems provide a distributed settings registry with access protection definable by application developers. Distributed settings registry may be implemented across different technologies with customizable privileges and the dynamic ability to plug different nodes into the registry tree. The settings registry may exist under a registry interface so the applications invoking the registry need not be concerned with where or how the settings data is stored. Each node in the tree of the registry may define its own privilege requirements and storage technology. Nodes may be “native” (i.e., fully supported within the setting registry system software) or “non-native” (i.e., defined by developers for specific applications).

Abstract: The present invention relates to dispersions of nanoureas comprising biologically active compounds, a process for their preparation, and their use.

Abstract: The invention relates to innovative compositions containing polyisocyanates containing allophanate groups and polyamines, preferably aromatic diamines, and optionally further polyisocyanates, preferably polyisocyanates containing uretdione groups, and also their use for producing quick-curing polyurea coatings.

Abstract: Methods and apparatus are provided for heating or cooling a patient's whole body or a selected portion of a patient's body. In one embodiment, the method begins by inserting a catheter having a dual balloon system into the large intestine of a patient. A heated or chilled liquid is conducted through a supply tube of the catheter and into the inner balloon. The liquid is evacuated from the inner balloon through a return lumen of the catheter. The outer balloon conducts heat transfer between the patient's tissues and the inner balloon, and further provides a degree of safety against rupture of the inner balloon.

Abstract: The invention relates to a process for producing polyurethane foams for wound management wherein a composition containing a polyurethane dispersion and specific coagulants is frothed and dried.

Abstract: The invention relates to a process for producing polyurethane foams, by frothing and drying specific polyurethane dispersions.

Abstract: The present invention relates to biomedical foam articles for the wound sector which are formed by spraying a polymeric dispersion onto a wound. The polymeric dispersion being sprayed onto a wound surface forms a three-dimensional body which conforms to the spatial shape of the wound and which, as well as covering the wound surface, ensures a complete and accurately fitted packing of the wound in the depth dimension as well as the other dimensions. The biomedical foam articles of the present invention are particularly useful for treating chronic wounds.

Abstract: The present invention relates to aqueous binder dispersions based on silane-modified polymeric binders and inorganic nanoparticles, a process for the preparation thereof and the use thereof for the production of high quality coatings, in particular clear lacquers.

Abstract: The present invention relates to biomedical foam articles for the wound sector which are formed by spraying a polymeric dispersion onto a wound. The polymeric dispersion being sprayed onto a wound surface forms a three-dimensional body which conforms to the spatial shape of the wound and which, as well as covering the wound surface, ensures a complete and accurately fitted packing of the wound in the depth dimension as well as the other dimensions. The biomedical foam articles of the present invention are particularly useful for treating chronic wounds.

Abstract: The present invention relates to nanoparticle-modified polyisocyanates which have been modified by a special siloxane unit and consequently have improved performance properties and also storage stabilities.

Abstract: The invention relates to a process for producing polyurethane foams, by frothing and drying mixtures of specific polyurethane dispersions and crosslinkers.

Abstract: The invention relates to a process for producing polyurethane foams for wound management wherein a composition containing a polyurethane dispersion and inorganic, cationic coagulants is frothed and dried.

Abstract: Processes comprising: (a) providing a composition comprising at least one silane-terminated polyurethane preploymer prepared by a process comprising: reacting (A) at least one polyether having a number average molecular weight (Mn) of 2000 to 8000 g/mol, and comprising 10 to 30 wt % ethylene oxide units based on all alkylene oxide units in the polyether; with (B) at least one isocyanate and alkoxysilane group-containing compound of the formula (I): wherein each of X, Y, and Z independently represents a C1-C8 alkyl or a C1-C8 alkoxy residue, with the proviso that at least one of X, Y, and Z represents a C1-C8 alkoxy group; and wherein R is an at least bifunctional, organic residue; (b) foaming the composition, and (c) curing the foamed composition in the presence of water; and uses of polyurethane foams prepared thereby.

Abstract: The present invention provides novel polyurethane-based wound dressing foams, obtained by foaming and curing silane-terminated polyurethanes.

Abstract: Embodiments of the invention provide a system for temperature control of the human body. The system includes an indwelling catheter with a tip-mounted heat transfer element. The catheter is fluidically coupled to a console that provides a heated or cooled heat transfer working fluid to exchange heat with the heat transfer element, thereby heating or cooling blood. The heated or cooled blood then heats or cools the patient's body or a selected portion thereof. In particular, strategies for optimizing the rewarming of patients for various medical procedures are provided, including stroke, neurosurgery, and myocardial infarction.

Abstract: The present invention relates to a process for preparing amino-functional polyurethane prepolymers by a) preparing an NCO-functional polyurethane prepolymer by reacting an excess of one or more di- and/or polyisocyanates with at least one isocyanate-reactive compound having a functionality of at least 1.5, b) reacting the free NCO groups of the resulting polyurethane prepolymer with at least one compound containing one or more silanol groups to obtain the corresponding silylurethanes, and then c) converting the silylurethanes to amino-functional polyurethane prepolymers by hydrolysis and/or alcoholysis with decarboxylation. The present invention also relates coatings, adhesives, sealants, casting compounds or moldings obtained from these amino-functional polyurethene prepolymers.

Abstract: Embodiments of the invention provide a system for temperature control of the human body. The system includes an indwelling catheter with a tip-mounted heat transfer element. The catheter is fluidically coupled to a console that provides a heated or cooled heat transfer working fluid to exchange heat with the heat transfer element, thereby heating or cooling blood. The heated or cooled blood then heats or cools the patient's body or a selected portion thereof. In particular, methods and devices, including software, are provided for administering cooling or rewarming and controlling the same based on a projected control temperature measured by a temperature sensor within the catheter.

Abstract: The present invention provides hydrogels formed from polyurethane (meth)acrylates in water using water-soluble redox initiators.

Abstract: A fluid level detector system, which may measure the amount of fluid in a reservoir, and may further trigger an alarm when the fluid level in the cassette reaches a low level condition. The cassette's reservoir may contain a transient sterile solution, which is moving through the cassette to be either cooled or heated in the heat exchanger area. The detection scheme includes a ring magnet housed in a float assembly located in the fluid reservoir of the cassette and, e.g., two magnetic sensors, such as may form a Hall effect integrated circuit, which may be fixed within the console.