Abstract: The present invention relates to innovative, nanoparticle-modified polyisocyanates, a process for their preparation and to their use in coating compositions and adhesives. The process comprises the steps of 1) reacting A) polyisocyanates with B) alkoxysilanes, and subsequently 2) incorporating by dispersion inorganic particles, optionally surface modified, having an average particle size of less than 200 nm as determined by means of dynamic light scattering in dispersion, where the alkoxysilanes are according to formula (I) Q-Z-SiXaY3-a??(I) in which Q is an isocyanate-reactive group, X is a hydrolysable group, Y is identical or different alkyl groups, Z is a C1-C12 alkylene group and a is an integer from 1 to 3.

Abstract: The invention concerns novel hydrogels, a process for the preparation of these hydrogels and would contact materials comprising these hydrogels. These polyurethane hydrogels are obtained by the reaction of aliphatic isocyanate prepolymers with polyols comprising tertiary nitrogen in water.

Abstract: Embodiments of the invention provide a system for temperature control of the human body. The system includes an indwelling catheter with a tip-mounted heat transfer element. The catheter is fluidically coupled to a console that provides a heated or cooled heat transfer working fluid to exchange heat with the heat transfer element, thereby heating or cooling blood. The heated or cooled blood then heats or cools the patient's body or a selected portion thereof. In particular, strategies for optimizing the rewarming of patients for various medical procedures are provided, including stroke, neurosurgery, and myocardial infarction.

Abstract: The invention relates to polyurethane foam forming compositions which produce hydrophilicized polyurethane foams, in particular foams which are suitable as wound dressing foams. These compositions comprise (I) a polyurethane dispersion and (II) specific additives including one or more alkylpolyglycoside. The process of producing these foams comprises frothing and drying these polyurethane foam forming compositions.

Abstract: The present invention relates to dispersions of nanoureas comprising biologically active compounds, a process for their preparation, and their use.

Abstract: The invention relates to a process for producing polyurethane foams for wound management. These polyurethane wound dressing foams are prepared by a process comprising frothing and drying of a foam foaming composition, which comprises a polyurethane dispersion and specific coagulants.

Abstract: The invention relates to a process for producing polyurethane wound dressing foams comprising frothing and drying polyurethane foam compositions which comprise anionically hydrophilicized aqueous polyurethane dispersions.

Abstract: A method and apparatus is provided for determining an effective thermal mass of a patient. The effective thermal mass is employed to determine a gain factor used in a feedback control system controlling patient temperature. The method begins by inducing hypothermia or hyperthermia in at least a selected portion of the patient with a device having a heat transfer surface. Next, power is transferred between the device and the patient. A change in temperature over time, which arises in the selected portion of the patient, is measured while performing the step of inducing hypothermia or hyperthermia. Finally, an effective thermal mass is calculated based on the measured power and the measured temperature change over time.

Abstract: The present invention relates to two-component coating systems for producing flexible coatings. The coating systems comprise polyurethane prepolymers with allophanate structures and also amino-functional polyaspartic esters as curing agents.

Abstract: The invention relates to innovative compositions containing polyisocyanates containing allophanate groups and polyamines, preferably aromatic diamines, and optionally further polyisocyanates, preferably polyisocyanates containing uretdione groups, and also their use for producing quick-curing polyurea coatings.

Abstract: Embodiments of the invention provide a system for temperature control of the human body. The system includes an indwelling catheter with a tip-mounted heat transfer element. The catheter is fluidically coupled to a console that provides a heated or cooled heat transfer working fluid to exchange heat with the heat transfer element, thereby heating or cooling blood. The heated or cooled blood then heats or cools the patient's body or a selected portion thereof. In particular, strategies for optimizing the rewarming of patients for various medical procedures are provided, including stroke, neurosurgery, and myocardial infarction.

Abstract: Polyamines having primary amino groups, preferably aromatic amino groups, are prepared in a one-stage process by hydrolyzing compounds containing terminal isocyanate groups. The polyamines produced are useful for preparing polyurethane ureas, which can be used in turn for producing coatings or porous (foams) or non-porous moldings.

Abstract: A device and method for providing body cooling for treating fever. The cooling device applies cooling to blood flowing in a vein or artery, e.g., the vena cavae, that is then distributed throughout the body.

Abstract: The present invention relates to novel polyurethane prepolymers (PU prepolymers) of low viscosity containing NCO groups blocked with compounds containing phenol groups and to their use for producing polyurethane polymers. The PU prepolymers are prepared by reacting one or more diisocyanates or polyisocyanates with at least one isocyanate-reactive compound with a functionality of at least 1.5 to form an NCO-functional polyurethane prepolymer and subsequently blocking the free NCO groups with at least one hydrocarbon resin containing phenolic OH groups and/or one optionally substituted phenol in the presence of a catalyst which comprises at least one triorganoamine.

Abstract: A device and method for providing body cooling for treating fever. The cooling device applies cooling to blood flowing in a vein or artery, e.g., the vena cavae, that is then distributed throughout the body.

Abstract: The invention relates to novel blocked polyurethane prepolymers, to a process for their preparation, to reactive systems prepared therefrom that cure at room temperature, and to their use.

Abstract: The present invention relates to a process for preparing blocked polyisocyanates wherein at least 50 mole % of the NCO groups have been blocked with sterically hindered phenols by reacting a) one or more organic polyisocyanates with b) one or more sterically hindered phenols in the presence of c) at least one catalyst selected from i) heterocyclic amines in which at least one nitrogen atom is part of an aliphatic, olefinic or aromatic ring, ii) tetraorganoammonium and tetraorganophosphonium salts of weak acids (pka?2.0), with nitrogen- and/or phosphorus-attached aliphatic, cycloaliphatic, araliphatic and/or aromatic radicals, and iii) zinc(II) compounds. The present invention also relates to the resulting blocked polyisocyanates and to their use for producing coatings, adhesives or sealants suitable for contact with foods and/or drinking water.

Abstract: Embodiments of the invention provide a system for temperature control of the human body. The system includes an indwelling catheter with a tip-mounted heat transfer element. The catheter is fluidically coupled to a console that provides a heated or cooled heat transfer working fluid to exchange heat with the heat transfer element, thereby heating or cooling blood. The heated or cooled blood then heats or cools the patient's body or a selected portion thereof. In particular, methods and devices, including software, are provided for administering cooling or rewarming and controlling the same based on a projected control temperature measured by a temperature sensor within the catheter.

Abstract: A process for preparing polyisocyanate prepolymers containing allophanate structural units that includes reacting a) one or more polyisocyanates with b) one or more polyetherpolyols containing less than or equal to 0.02 milliequivalent of unsaturated end groups per gram of polyol and having a polydispersity of from 1.0 to 1.5 and/or an OH functionality of greater than or equal to 1.9 ?to provide an NCO-functional polyurethane prepolymer containing urethane groups that are partly or fully allophanatized by further reaction with c) polyisocyanates, which may be different from those from a), and d) catalysts and optionally adding e) acidic additives before, during and/or after the allophanatization. The polyisocyanate prepolymers can be used to produce coatings, adhesive bonds and/or seals. The coatings include one or more of the polyisocyanate prepolymers, and at least one diol or polyol and/or at least one linear and/or cyclic, aliphatic, araliphatic and/or aromatic diamine or polyamine.

Abstract: The present invention relates to a process for preparing amino-functional polyurethane prepolymers by a) preparing an NCO-functional polyurethane prepolymer by reacting an excess of one or more di- and/or polyisocyanates with at least one isocyanate-reactive compound having a functionality of at least 1.5, b) reacting the free NCO groups of the resulting polyurethane prepolymer with at least one compound containing one or more silanol groups to obtain the corresponding silylurethanes, and then c) converting the silylurethanes to amino-functional polyurethane prepolymers by hydrolysis and/or alcoholysis with decarboxylation. The present invention also relates coatings, adhesives, sealants, casting compounds or moldings obtained from these amino-functional polyurethene prepolymers.