Patents by Inventor Michael Major
Michael Major has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20060098833Abstract: A soft-solid ear piece is formed to fit the typical human ear canal and will self form to fill the ear cavity by having an internal structure, endoskeleton, or bladder to expand to precisely fit the ear piece securely and comfortably in the ear canal. This self forming ear piece will enable ready-ware and custom molded hearing aids, hearing protectors, audio ear pieces, cell phone ear pieces and assistive listening devices to fit comfortably, securely, and free of acoustic feedback in the external ear canal. It creates an acoustic seal to optimally reduce peripheral leakage and intermodulation distortion delivering excellent acoustic performance while keeping environmental sounds blocked out.Type: ApplicationFiled: May 26, 2005Publication date: May 11, 2006Inventors: Roger Juneau, Brian Tanner, Edward Desporte, Michael Major, Gregory Siegle
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Publication number: 20060014688Abstract: The invention provides methods for inhibiting tumor cell proliferation by inhibiting FoxM1B activity, expression, or nuclear localization in a tumor cell. The invention also provides methods for preventing tumor progression in an animal comprising inhibiting FoxM1B activity, expression, or nuclear localization. Furthermore, the invention provides methods for inhibiting tumor cell growth in an animal comprising inhibiting FoxM1B activity, expression, or nuclear localization in tumor cells in the animal.Type: ApplicationFiled: June 10, 2005Publication date: January 19, 2006Inventors: Robert Costa, Pradip Raychaudhuri, I-Ching Wang, Vladimir Kalinichenko, Michael Major, Xinhe Wang
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Publication number: 20050277686Abstract: This invention relates to a family of phenylbenzimidazole analogs, which are inhibitors of the IgE response to allergens. These compounds are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic.Type: ApplicationFiled: June 28, 2005Publication date: December 15, 2005Inventors: Jagadish Sircar, Mark Richards, Michael Campbell, Michael Major
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Publication number: 20050141739Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a plate member with electronic hearing aid components mounted thereto. The plate member is preferably of a harder material such as hard plastic. A soft polymeric body is bonded to the plate member and encapsulates preferably a plurality of the electronic hearing aid components. The body is soft and is shaped to conform to the ear canal of the user. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal. This combination of soft compliant structure and encapsulated electronic hearing aid components addresses problems of peripheral leakage, poor fit, pivotal displacement that occurs with jaw motion and internal cross talk of components housed in prior art hollow type hearing aids.Type: ApplicationFiled: March 1, 2004Publication date: June 30, 2005Applicant: SOFTEAR TECHNOLOGIES, L.L.C. (a Louisiana Limited Liability Company)Inventors: Roger Juneau, Edward Desporte, Michael Major, Gregory Siegle
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Publication number: 20050075343Abstract: This invention relates to a family of benzimidazole analogs, which are inhibitors of the IgE response to allergens. These compounds are useful in the treatment of allergy, asthma, or any diseases where IgE is pathogenic.Type: ApplicationFiled: September 28, 2004Publication date: April 7, 2005Inventors: Jagadish Sircar, Mark Richards, Michael Campbell, Michael Major
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Publication number: 20050032692Abstract: The invention provides methods for inhibiting tumor cell proliferation by inhibiting FoxM1B activity, expression, or nuclear localization in a tumor cell. The invention also provides methods for preventing tumor progression in an animal comprising inhibiting FoxM1B activity, expression, or nuclear localization. Furthermore, the invention provides methods for inhibiting tumor cell growth in an animal comprising inhibiting FoxM1B activity, expression, or nuclear localization in tumor cells in the animal.Type: ApplicationFiled: March 25, 2004Publication date: February 10, 2005Inventors: Robert Costa, Pradip Raychaudhuri, I-Ching Wang, Vladimir Kalinichenko, Michael Major, Xinhe Wang
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Publication number: 20040252854Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a plate member with electronic hearing aid components mounted thereto. The plate member is preferably of a harder material such as hard plastic. A soft polymeric body is bonded to the plate member and encapsulates preferably a plurality of the electronic hearing aid components. The body is soft and is shaped to conform to the ear canal of the user. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal. This combination of soft compliant structure and encapsulated electronic hearing aid components addresses problems of peripheral leakage, poor fit, pivotal displacement that occurs with jaw motion and internal cross talk of components housed in prior art hollow type hearing aids.Type: ApplicationFiled: February 23, 2004Publication date: December 16, 2004Applicant: SOFTEAR TECHNOLOGIES, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Patent number: 6761789Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a receptacle with electronic hearing aid components mounted thereto. The receptacle has a cavity for holding electronic components (eg. battery, microphone, amplifier). A soft polymeric body is preliminarily formed by encapsulating a plurality of the electronic hearing aid component shaped inserts. The body is soft and is shaped to conform to the ear canal of the user. After forming, the insert is removed to provide an insert cavity that can carry electronic components. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal.Type: GrantFiled: March 11, 2002Date of Patent: July 13, 2004Assignee: Softear Technologies, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Publication number: 20040109844Abstract: The invention provides a method of preventing or amelioriating age-related proliferation defects or age-related diseases in a patient by stimulating FoxM1B protein expression, nuclear localization, or both protein expression and nuclear localization of FoxM1B or by introducing a recombinant nucleic acid construct that comprises a truncated FoxM1B gene into target cells, thereby restoring proliferative potential of the target cells. The invention also provides a method of treating diseases or disorders associated with premature aging. The invention further provides a method of treating or ameliorating lung damage. Specifically, the methods of the invention comprise inducing expression and nuclear localization of FoxM1B protein in a target cell by contacting the cell with a growth factor or a cytokine.Type: ApplicationFiled: August 28, 2003Publication date: June 10, 2004Applicant: The Board of Trustees of the University of IllinoisInventors: Robert H. Costa, Xinhe Wang, Yongjun Tan, Vladimir Kalinichenko, Katherine Krupczak-Hollis, I-Ching Wang, Michael Major
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Patent number: 6728383Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a plate member with electronic hearing aid components mounted thereto. The plate member is preferably of a harder material such as hard plastic. A soft polymeric body is bonded to the plate member and encapsulates preferably a plurality of the electronic hearing aid components. The body is soft and is shaped to conform to the ear canal of the user. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal. This combination of soft compliant structure and encapsulated electronic hearing aid components addresses problems of peripheral leakage, poor fit, pivotal displacement that occurs with jaw motion and internal cross talk of components housed in prior art hollow type hearing aids.Type: GrantFiled: October 28, 1998Date of Patent: April 27, 2004Assignee: Softear Technologies, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Patent number: 6695943Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a plate member with electronic hearing aid components mounted thereto. The plate member is preferably of a harder material such as hard plastic. A soft polymeric body is bonded to the plate member and encapsulates preferably a plurality of the electronic hearing aid components. The body is soft and is shaped to conform to the ear canal of the user. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal. This combination of soft compliant structure and encapsulated electronic hearing aid components addresses problems of peripheral leakage, poor fit, pivotal displacement that occurs with jaw motion and internal cross talk of components housed in prior art hollow type hearing aids.Type: GrantFiled: May 14, 2001Date of Patent: February 24, 2004Assignee: Softear Technologies, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Publication number: 20020198437Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a receptacle with electronic hearing aid components mounted thereto. The receptacle has a cavity for holding electronic components (eg. battery, microphone, amplifier). A soft polymeric body is preliminarily formed by encapsulating a plurality of the electronic hearing aid component shaped inserts. The body is soft and is shaped to conform to the ear canal of the user. After forming, the insert is removed to provide an insert cavity that can carry electronic components. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal.Type: ApplicationFiled: March 11, 2002Publication date: December 26, 2002Applicant: SOFTEAR TECHNOLOGIES, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Patent number: 6473512Abstract: An apparatus and method of manufacturing a soft-solid elastomer custom ear device into which electronics are embedded provides a completely in-the-ear hearing aid with a soft body. This technology replaces hard acrylic ear molding. This hearing aid by virtue of its soft-solid design, meets the needs of the dynamic human ear canal which cannot be met with conventional hard acrylic molding. This hearing aid provides improved comfort and sound quality by better adapting to the dynamic changes in the ear canal which occur during everyday activities. This soft custom body also provides for ear-worn configurations of all subminiature electronic devices requiring discrete coupling to the human ear. These devices include digital telephones, cellular telephones, pagers, two-way communication systems, clocks, recorders, and many other subminiature technologies.Type: GrantFiled: October 28, 1998Date of Patent: October 29, 2002Assignee: Softear Technologies, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Patent number: 6438244Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a plate member with electronic hearing aid components mounted thereto. The plate member is preferably of a harder material such as hard plastic. A soft polymeric body is bonded to the plate member and encapsulates preferably a plurality of the electronic hearing aid components. The body is soft and is shaped to conform to the ear canal of the user. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal. This combination of soft compliant structure and encapsulated electronic hearing aid components addresses problems of peripheral leakage, poor fit, pivotal displacement that occurs with jaw motion and internal cross talk of components housed in prior art hollow type hearing aids.Type: GrantFiled: October 28, 1998Date of Patent: August 20, 2002Assignee: Softear TechnologiesInventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Patent number: 6434248Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a plate member with electronic hearing aid components mounted thereto. The plate member is preferably of a harder material such as hard plastic. A soft polymeric body is bonded to the plate member and encapsulates preferably a plurality of the electronic hearing aid components. The body is soft and is shaped to conform to the ear canal of the user. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal. This combination of soft compliant structure and encapsulated electronic hearing aid components addresses problems of peripheral leakage, poor fit, pivotal displacement that occurs with jaw motion and internal cross talk of components housed in prior art hollow type hearing aids.Type: GrantFiled: October 28, 1998Date of Patent: August 13, 2002Assignee: Softear Technologies, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Patent number: 6432247Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a plate member with electronic hearing aid components mounted thereto. The plate member is preferably of a harder material such as hard plastic. A soft polymeric body is bonded to the plate member and encapsulates preferably a plurality of the electronic hearing aid components. The body is soft and is shaped to conform to the ear canal of the user. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal. This combination of soft compliant structure and encapsulated electronic hearing aid components addresses problems of peripheral leakage, poor fit, pivotal displacement that occurs with jaw motion and internal cross talk of components housed in prior art hollow type hearing aids.Type: GrantFiled: October 28, 1998Date of Patent: August 13, 2002Assignee: Softear Technologies, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Publication number: 20020032362Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a plate member with electronic hearing aid components mounted thereto. The plate member is preferably of a harder material such as hard plastic. A soft polymeric body is bonded to the plate member and encapsulates preferably a plurality of the electronic hearing aid components. The body is soft and is shaped to conform to the ear canal of the user. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal. This combination of soft compliant structure and encapsulated electronic hearing aid components addresses problems of peripheral leakage, poor fit, pivotal displacement that occurs with jaw motion and internal cross talk of components housed in prior art hollow type hearing aids.Type: ApplicationFiled: May 14, 2001Publication date: March 14, 2002Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Patent number: 6354990Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a receptacle with electronic hearing aid components mounted thereto. The receptacle has a cavity for holding electronic components (eg. battery, microphone, amplifier). A soft polymeric body is preliminarily formed by encapsulating a plurality of the electronic hearing aid component shaped inserts. The body is soft and is shaped to conform to the ear canal of the user. After forming, the insert is removed to provide an insert cavity that can carry electronic components. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal.Type: GrantFiled: May 13, 1999Date of Patent: March 12, 2002Assignee: Softear Technology, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Patent number: 6254526Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a plate member with electronic hearing aid components mounted thereto. The plate member is preferably of a harder material such as hard plastic. A soft polymeric body is bonded to the plate member and encapsulates preferably a plurality of the electronic hearing aid components. The body is soft and is shaped to conform to the ear canal of the user. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal. This combination of soft compliant structure and encapsulated electronic hearing aid components addresses problems of peripheral leakage, poor fit, pivotal displacement that occurs with jaw motion and internal cross talk of components housed in prior art hollow type hearing aids.Type: GrantFiled: October 28, 1998Date of Patent: July 3, 2001Assignee: Softear Technologies, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler
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Patent number: 6228020Abstract: A hearing aid instrument of the in-the-ear type (and preferably CIC) provides a plate member with electronic hearing aid components mounted thereto. The plate member is preferably of a harder material such as hard plastic. A soft polymeric body is bonded to the plate member and encapsulates preferably a plurality of the electronic hearing aid components. The body is soft and is shaped to conform to the ear canal of the user. The soft polymeric body and encapsulated electronic hearing aid components define a soft structure compliant to the ear canal during use and that is substantially solid and free of void spaces between at least some of the components and the ear canal. This combination of soft compliant structure and encapsulated electronic hearing aid components addresses problems of peripheral leakage, poor fit, pivotal displacement that occurs with jaw motion and internal cross talk of components housed in prior art hollow type hearing aids.Type: GrantFiled: October 28, 1998Date of Patent: May 8, 2001Assignee: Softear Technologies, L.L.C.Inventors: Roger P. Juneau, Lynn P. Creel, Edward J. Desporte, Michael Major, Gregory R. Siegle, Kelly M. Kinler