Abstract: A collapsible utility cart includes an elongate frame having upper and lower ends. A handle is formed proximate the upper end of the frame. A pair of wheels are axially rotatably connected to the frame and are pivotable between an open condition wherein the wheels are axially aligned with one another and a folded condition wherein the wheels are axially parallel to one another. Upper and lower support element are interconnected pivotally to the frame and are alternatable between collapsed conditions folded against the frame and open conditions extending forwardly from the frame. A plurality of clips are carried by the upper support element for securing a collection bag to the upper support element.

Abstract: A method of tracking an entity includes generating data relevant to the entity at a first location, storing the data at a server, and accessing at least a portion of the data at the first location or at a second location. The data can include location information, time information, image data, text, and/or biometric data. The data can be encrypted, organized, categorized, updated, accumulated with other data, classified, and/or disseminated, and an automated search can include an image feature recognition and facial recognition search. The entity can be a person, an animal, or an object. A communications system includes a processing device and a server that includes an automated search engine. The server can be configured to perform data analysis, such as data grouping.

Abstract: The present invention comprises a novel mattress extension device that can be fixed or that is adjustable for depth and height, which is portable, and capable of conforming the device to the contours of any given mattress and box spring. In preferred embodiments, the various elements of the mattress extender device are each configured to meet the specifications of any or all applications.

Abstract: The present invention comprises a novel mattress extension device that can be fixed or that is adjustable for depth and height, which is portable, and capable of conforming the device to the contours of any given mattress and box spring. In preferred embodiments, the various elements of the mattress extender device are each configured to meet the specifications of any or all applications.

Abstract: A paddle for a watercraft or flotation device has a pair of shaft mounted blades connected by a core member. A right hand drive grip and a left hand drive grip are secured in spaced relation to opposite ends of the core. A right hand offset is mounted adjacent the right hand drive grip and a left hand offset is mounted adjacent the left hand drive grip for providing hand clearance for a user. The core is telescopically expandable and accommodates various size paddle shafts for propelling different watercraft.

Abstract: A paddle for a waterdraft or flotation device has a pair of shaft mounted blades connected by a core member. A right hand drive grip and a left hand drive grip are secured in spaced relation to opposite ends of the core. A right hand offset is mounted adjacent the right hand drive grip and a left hand offset is mounted adjacent the left hand drive grip for providing hand clearance for a user. The core is telescopically expandable and accommodates various size paddle shifts for propelling different watercraft.

Abstract: A method of tracking an entity includes generating data relevant to the entity at a first location, storing the data at a server, and accessing at least a portion of the data at the first location or at a second location. The data can include location information, time information, image data, text, and/or biometric data. The data an be encrypted, organized, categorized, updated, accumulated with other data, classified, and/or disseminated, and an automated search can include an image feature recognition and facial recognition search. The entity can be a person, an animal, or an object. A communications system includes a processing device and a server that includes an automated search engine. The server can be configured to perform data analysis, such as data grouping.

Abstract: The proliferation and activation of microglia is emerging as an important etiologic factor and target for therapeutic intervention in several CNS diseases, including Alzheimer's disease and multiple sclerosis. Here, we have discovered that retinoic acids dramatically inhibit microglial proliferation in an in vivo model including the widely-used animal model of multiple sclerosis, the experimental autoimmune encephalomyelitis (EAE) mouse model.

Abstract: An mGluR4 receptor positive allosteric modulator is useful, alone or in combination with a neuroleptic agent, for treating or preventing movement disorders such as Parkinson's disease, dyskinesia, tardive dyskinesia, drug-induced parkinsonism, postencephalitic parkinsonism, progressive supranuclear palsy, multiple system atrophy, corticobasal degeneration, parkinsonian-ALS dementia complex, basal ganglia calcification, akinesia, akinetic-rigid syndrome, bradykinesia, dystonia, medication-induced parkinsonian, Gilles de la Tourette syndrome, Huntington's disease, tremor, chorea, myoclonus, tick disorder, and dystonia.

Abstract: A system for suppressing ambient signals from a signal containing radiated emissions of a electronic device and ambient signals. The system comprises a first receiver operative to receive the ambient signals and the radiated emissions from the electronic device. The first receiver is operative to demodulate and digitize the ambient signals and the radiated emissions. The system further comprises a second receiver operative to receive primarily the ambient signals wherein the second receiver is time and frequency synchronized to the first receiver and operative to demodulate and digitize the ambient signals. A central computer is in electrical communication with the first and second receivers and is operative to store and process the ambient signals and the radiated emissions from respective ones of the first and second receivers. Accordingly, the central computer is configured as an adaptive filter operative to suppress the ambient signals correlated between the first and second receivers.

Abstract: Methods, compositions, and kits for detecting mutations in the entire human mitochondrial genome. A preferred method includes amplifying mtDNA from a biological sample by polymerase chain reaction of total DNA using a plurality of pre-selected primer pairs to generate overlapping amplicons; cleaving the amplicons using restriction enzymes to produce fragments suitable for analysis by denaturing high performance liquid chromatography (DHPLC); denaturing and re-annealing the amplicons; and fragment analysis by DHPLC to detect the presence or absence of heteroduplex molecules.

Abstract: Methods, systems, compositions and kits for improved detection of polynucleotides. In one aspect, there is provided a method for separating polynucleotides (such as DNA or RNA) using a liquid chromatographic separation device (such as a reverse phase column or an ion exchange column), contacting eluted polynucleotides with intercalating dye, and detecting (such as by fluorescence detection) dye bound to the eluted polynucleotides. The invention preferably uses a post-column reactor, such as a mixing tee, downstream of the separation column. Sensitivity of mutation detection by denaturing high performance liquid chromatography (DHPLC) is enhanced.

Abstract: A dual tamper evident container closure for a dispensing container, the cap portion being of a type intended to be held permanently captive on the container having a nozzle dispensing opening, multiple sealing flanges and dual locking engagement beads to retain the cap portion on the container. The closure portion is registerable over the dispensing opening and retained to the cap portion by a flexible web. Both the cap portion and the closure portion have depending interconnected frangible bands that engage and are retained on the respective container and nozzle to indicate prior opening or tampering with the container closure.

Abstract: The invention is a method of measuring transfer functions of a physical system using a wideband excitation signal by exciting the system with a low-power, wide band input signal that has a rich frequency content over a wide band and using a stochastic process to derive a system transfer function over the excitation signal bandwidth.

Abstract: A cap for use on containers to selectively dispense individual pre-moistened tissues from a web of perforated tissues. The cap is removably secured to a container body having a top portion with a depending annular flange on its peripheral edge and a dispensing recess centered within. An integral access lid extends from the top portion for sealing registration over the dispensing recess. A dispensing outlet is formed within the dispensing recess through which the tissues may be removed.

Abstract: An anti-creeping cap to prevent the self unscrewing of a cap from a container used for edible products. The cap has an internal screw thread and multiple spaced engagement ribs extending from a secondary depending annular flange that correspondingly engaged to a number of registering projections extending from the neck finish of the container. Moderate torsional rotation input force is required to disengage the registering projections from grooves formed between the ribs which is accomplished by the flexation of the flange for cap removal.

Abstract: A pour spout closure for use on containers comprising, a cap configuration having a pour spout and a return reservoir integrally joined to a closure by a live hinge. A secondary cap is formed on the closure that is registerable in the return reservoir when the closure is in closed position holding the secondary cap and closure in closed position.

Abstract: A container and cap assembly of the type comprising an integral molded container and hinge cap. The container having a neck surrounding an opening thereto with a rim extending thereabout. The cap is interconnected to the container by a living hinge, aligning the cap with the neck for sealing registration thereon. Engagement and release tabs extend from the respective container and cap portions for angularly aligned positioning to one another upon cap registration on the container.

Abstract: A tamper evident resealable cap for use on a bottle, the cap having an upstanding spout that is registerable with an opening in the center of the cap and a sealing plug of a smaller diameter positioned thereabove on multiple upstanding legs extending from the spout. An over cap extends over the spout, enclosing the spout with a tamper evident enclosure. The improvement is directed towards a detachable annular ring secured to the over cap by a plurality of frangible elements thereabout, the ring is arranged for restrictive registration with a locking shoulder that extends from the top of the cap body. The cap body has a tamper evident tear band extending from the cap with a frangible tear line therein. A tear tab extends from the tear band for selective engagement by the user to remove the tear band.

Abstract: A tamper evident resealable cap for use on a bottle, the cap having an upstanding spout that is registerable with an opening in the center of the cap and a sealing plug of a smaller diameter positioned thereabove on multiple upstanding legs extending from the spout. The improvement is directed towards a detachable annular ring secured to the cap by a plurality of frangible elements thereabout, the ring is arranged for restrictive registration with a locking shoulder that extends from the top of the cap body. The cap body has a tamper evident band secured to the cap by a plurality of circumferentially spaced frangible elements with a plurality of annularly spaced radially inwardly extending annular projections and is registerable with a neck portion of the bottle to prevent rotation in one direction without removal of the tamper evident ring.