Patents by Inventor Michael Mark

Michael Mark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12631525
    Abstract: A method of operation is provided. During this method, a first power system of an aircraft powerplant is operated to direct a first quantity of fuel into a flowpath of the aircraft powerplant for combustion. A second power system of the aircraft powerplant is tested during the operating of the first power system. The testing of the second power system includes: signaling the second power system to direct a second quantity of fuel into the flowpath for combustion; determining an operational parameter of the aircraft powerplant following the signaling; and evaluating operability of the second power system by comparing the operational parameter to a threshold.
    Type: Grant
    Filed: June 26, 2023
    Date of Patent: May 19, 2026
    Assignee: Pratt & Whitney Canada Corp.
    Inventors: Michael Mark, Michael Hanna
  • Publication number: 20260097058
    Abstract: The invention relates to the treatment or prevention of one or more conditions selected from type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance and hyperglycemia using a SGLT-2 inhibitor. In addition the present invention relates to methods for preventing or treating of metabolic disorders and related conditions.
    Type: Application
    Filed: December 11, 2025
    Publication date: April 9, 2026
    Inventors: Peter EICKELMANN, Michael Mark, Leo John Seman, Leo Thomas, Uli Christian Broedl, Rolf Grempler
  • Patent number: 12527810
    Abstract: The invention relates to the treatment or prevention of one or more conditions selected from type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance and hyperglycemia using a SGLT-2 inhibitor. In addition the present invention relates to methods for preventing or treating of metabolic disorders and related conditions.
    Type: Grant
    Filed: June 3, 2022
    Date of Patent: January 20, 2026
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Peter Eickelmann, Michael Mark, Leo John Seman, Leo Thomas, Uli Christian Broedl, Rolf Grempler
  • Patent number: 12312352
    Abstract: The present invention relates to methods for treating and/or preventing SIRS and/or sepsis comprising the administration of an effective amount of a certain DPP-4 inhibitor, as well as to the use of a certain DPP-4 inhibitor for treating and/or preventing a metabolic disease in a patient with or at risk of SIRS and/or sepsis.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: May 27, 2025
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thomas Klein, Andreas Daiber, Klaus Dugi, Michael Mark, Thomas Muenzel
  • Patent number: 12291347
    Abstract: A hybrid powerplant is provided for an aircraft. This hybrid powerplant includes a housing, an electric machine, a machine fluid circuit, a heat engine and a geartrain. The housing includes a machine containment zone and an engine compartment outside of the machine containment zone. The electric machine is arranged within the machine containment zone. The machine fluid circuit services the electric machine. The machine fluid circuit extends in the machine containment zone and is arranged outside of the engine compartment. The heat engine is arranged within the engine compartment. The geartrain is operatively connected to the electric machine and the heat engine.
    Type: Grant
    Filed: July 31, 2023
    Date of Patent: May 6, 2025
    Assignee: PRATT & WHITNEY CANADA CORP.
    Inventors: Michael Mark, Ion Dinu
  • Publication number: 20250082642
    Abstract: The present invention relates to the finding that certain DPP-4 inhibitors are particularly suitable for treating and/or preventing metabolic diseases, particularly diabetes, in patients with insufficient glycemic control despite a therapy with an oral and/or a non-oral antidiabetic drug.
    Type: Application
    Filed: November 27, 2024
    Publication date: March 13, 2025
    Inventors: Eva Ulrike GRAEFE-MODY, Thomas KLEIN, Michael MARK, Hans-Juergen WOERLE
  • Publication number: 20250064819
    Abstract: The specification describes the use of selected DPP IV inhibitors for the treatment of physiological functional disorders and for reducing the risk of the occurrence of such functional disorders in at-risk patient groups. In addition, the use of the above-mentioned DPP IV inhibitors in conjunction with other active substances is described, by means of which improved treatment outcomes can be achieved. These applications may be used to prepare corresponding medicaments.
    Type: Application
    Filed: November 13, 2024
    Publication date: February 27, 2025
    Inventors: Klaus DUGI, Frank HIMMELSBACH, Michael MARK
  • Publication number: 20250042567
    Abstract: A hybrid powerplant is provided for an aircraft. This hybrid powerplant includes a housing, an electric machine, a machine fluid circuit, a heat engine and a geartrain. The housing includes a machine containment zone and an engine compartment outside of the machine containment zone. The electric machine is arranged within the machine containment zone. The machine fluid circuit services the electric machine. The machine fluid circuit extends in the machine containment zone and is arranged outside of the engine compartment. The heat engine is arranged within the engine compartment. The geartrain is operatively connected to the electric machine and the heat engine.
    Type: Application
    Filed: July 31, 2023
    Publication date: February 6, 2025
    Inventors: Michael Mark, Ion Dinu
  • Publication number: 20240426708
    Abstract: A method of operation is provided. During this method, a first power system of an aircraft powerplant is operated to direct a first quantity of fuel into a flowpath of the aircraft powerplant for combustion. A second power system of the aircraft powerplant is tested during the operating of the first power system. The testing of the second power system includes: signaling the second power system to direct a second quantity of fuel into the flowpath for combustion; determining an operational parameter of the aircraft powerplant following the signaling; and evaluating operability of the second power system by comparing the operational parameter to a threshold.
    Type: Application
    Filed: June 26, 2023
    Publication date: December 26, 2024
    Inventors: Michael Mark, Michael Hanna
  • Publication number: 20240426253
    Abstract: A system is provided for an aircraft. This aircraft system includes a propulsor rotor and a powerplant configured to drive rotation of the propulsor rotor. The powerplant includes a turbine section, a flowpath, a first fuel system and a second fuel system fluidly independent of the first fuel system. The turbine section includes a turbine rotor. The flowpath extends through the turbine section from an inlet into the flowpath to an exhaust from the flowpath. The first fuel system is configured to direct first fuel into the flowpath between the inlet and the turbine rotor. The second fuel system is configured to direct second fuel into the flowpath between the inlet and the turbine rotor.
    Type: Application
    Filed: June 26, 2023
    Publication date: December 26, 2024
    Inventors: Michael Mark, Michael Hanna
  • Publication number: 20240425188
    Abstract: A method of operation is provided. During this method, a first power system of an aircraft powerplant is operated to provide a first quantity of power and/or torque to drive rotation of a propulsor rotor. A second power system of the aircraft powerplant is tested during the operating of the first power system. The second power system is configured as or otherwise includes an electric machine. The testing of the second power system includes: signaling the second power system to use the electric machine to provide a second quantity of power and/or torque to further drive the rotation of the propulsor rotor; determining an operational parameter of the aircraft powerplant following the signaling; and evaluating operability of the second power system by comparing the operational parameter to a threshold.
    Type: Application
    Filed: June 26, 2023
    Publication date: December 26, 2024
    Inventors: Michael Mark, Michael Hanna
  • Patent number: 12171767
    Abstract: The specification describes the use of selected DPP IV inhibitors for the treatment of physiological functional disorders and for reducing the risk of the occurrence of such functional disorders in at-risk patient groups. In addition, the use of the above-mentioned DPP IV inhibitors in conjunction with other active substances is described, by means of which improved treatment outcomes can be achieved. These applications may be used to prepare corresponding medicaments.
    Type: Grant
    Filed: February 28, 2022
    Date of Patent: December 24, 2024
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Klaus Dugi, Frank Himmelsbach, Michael Mark
  • Patent number: 12115179
    Abstract: The invention relates to a pharmaceutical composition comprising an SGLT2 inhibitor, a DPPIV inhibitor and a third antidiabetic agent which is suitable in the treatment or prevention of one or more conditions selected from type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance and hyperglycemia. In addition the present invention relates to methods for preventing or treating of metabolic disorders and related conditions.
    Type: Grant
    Filed: May 19, 2023
    Date of Patent: October 15, 2024
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Peter Eickelmann, Michael Mark, Leo John Seman, Leo Thomas, Uli Christian Broedl, Rolf Grempler
  • Publication number: 20240335514
    Abstract: The invention relates to a pharmaceutical composition according to the claim 1 comprising an SGLT2 inhibitor and an insulin which is suitable in the treatment or prevention of one or more conditions selected from type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance and hyperglycemia.
    Type: Application
    Filed: June 18, 2024
    Publication date: October 10, 2024
    Inventors: Rolf GREMPLER, Odd-Erik JOHANSEN, Thomas KLEIN, Gerd Roland LUIPPOLD, Michael MARK
  • Patent number: 12110125
    Abstract: A hybrid electric propulsion (HEP) system can include a heat engine torque sensor connected between a heat engine and a combining gear box to sense a heat motor input torque input to the combining gear box, an electric motor torque sensor connected between an electric motor and the combining gear box to sense an electric motor input torque input to the combining gear box, and a combining gear box torque sensor connected to an output of the combining gearbox. The system can include a HEP controller operatively connected to each of the heat engine torque sensor, the electric motor torque sensor, and the combining gear box torque sensor to receive one or more torque signals therefrom. The controller can be configured to output one or more output signals as a function of the signals from each of the heat engine torque sensor, the electric motor torque sensor, and the combining gear box torque sensor.
    Type: Grant
    Filed: December 18, 2023
    Date of Patent: October 8, 2024
    Assignee: PRATT & WHITNEY CANADA CORP.
    Inventors: Michael Mark, Paul C. Imel, Leonid Guerchkovitch
  • Publication number: 20240309922
    Abstract: A brake disc, also referred to as a rotor, for a disc brake has the function of interacting with a brake lining as a friction partner in the disc brake. The brake disc is formed at least in part of a material having a molybdenum content of ?50 wt. %.
    Type: Application
    Filed: February 3, 2022
    Publication date: September 19, 2024
    Inventors: Walter Hammerle, Michael Eidenberger-Schober, Michael Mark, Peter Loidolt
  • Publication number: 20240299399
    Abstract: The present invention relates to methods for treating and/or preventing podocytes related disorders and/or nephrotic syndrome comprising the administration of an effective amount of a certain DPP-4 inhibitor, as well as to the use of a certain DPP-4 inhibitor for treating and/or preventing a metabolic disease in a patient with or at risk of podocytes related disorders and/or nephrotic syndrome.
    Type: Application
    Filed: May 23, 2024
    Publication date: September 12, 2024
    Inventors: Thomas KLEIN, Maximilian von EYNATTEN, Michael MARK
  • Publication number: 20240156823
    Abstract: The present invention relates to certain DPP-4 inhibitors for treating and/or preventing oxidative stress, vascular stress and/or endothelial dysfunction as well as to the use of such DPP-4 inhibitors in treatment and/or prevention of diabetic or non-diabetic patients, including patient groups at risk of cardiovascular and/or renal disease.
    Type: Application
    Filed: January 10, 2024
    Publication date: May 16, 2024
    Inventors: Thomas KLEIN, Andreas DAIBER, Odd-Erik JOHANSEN, Michael MARK, Sanjaykumar PATEL, Hans-Juergen WOERLE
  • Publication number: 20240148737
    Abstract: The present invention relates to the finding that certain DPP-4 inhibitors are particularly suitable for treating and/or preventing metabolic diseases, particularly diabetes, in patients with insufficient glycemic control despite a therapy with an oral and/or a non-oral antidiabetic drug.
    Type: Application
    Filed: January 16, 2024
    Publication date: May 9, 2024
    Inventors: Eva Ulrike GRAEFE-MODY, Thomas KLEIN, Michael MARK, Hans-Juergen WOERLE
  • Publication number: 20240117496
    Abstract: A component formed of a refractory metal has a surface that is at least partially coated with a layer of yttria. There is also described a method of manufacturing a coated component, and the application of Y2O3 as a release agent in high temperature applications.
    Type: Application
    Filed: November 25, 2021
    Publication date: April 11, 2024
    Inventors: Robert Schiftner, Katrin Knittl, Thomas Huber, Michael Mark