Patents by Inventor Michael Michaelides

Michael Michaelides has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOINDOLINONE KINASE INHIBITORS
    Publication number: 20100076051
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: November 25, 2009
    Publication date: March 25, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Michael L. Curtin, Steven K. Davidsen, Robin R. Frey, Howard R. Heyman, James H. Holms, Michael Michaelides, Douglas H. Steinman
  • INDAZOLE, BENZISOXAZOLE, AND BENZISOTHIAZOLE KINASE INHIBITORS
    Publication number: 20080076767
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: October 5, 2007
    Publication date: March 27, 2008
    Inventors: Yujia Dai, Steven Davidsen, Anna Ericsson, Kresna Hartandi, Zhiqin Ji, Michael Michaelides
  • THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS
    Publication number: 20070155776
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: February 15, 2007
    Publication date: July 5, 2007
    Inventors: Patrick Betschmann, Andrew Burchat, David Calderwood, Michael Curtin, Steven Davidsen, Heather Davis, Robin Frey, Howard Heyman, Gavin Hirst, Peter Hrnciar, Michael Michaelides, Melanie Muckey, Kelly Mullen, Paul Rafferty, Carol Wada
  • Inhibitors of protein kinases
    Publication number: 20070135387
    Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
    Type: Application
    Filed: December 8, 2006
    Publication date: June 14, 2007
    Inventors: Michael Michaelides, William McClellan, Robin Frey, Michael Curtin, Douglas Steinman, Yujia Dai, James Holms
  • Isoindolinone kinase inhibitors
    Publication number: 20060287370
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: August 25, 2006
    Publication date: December 21, 2006
    Inventors: Michael Curtin, Steven Davidsen, Robin Frey, Howard Heyman, James Holms, Michael Michaelides, Douglas Steinman
  • Thiopyrimidine and isothiazolopyrimidine Kinase Inhibitors
    Publication number: 20060276490
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: August 16, 2006
    Publication date: December 7, 2006
    Inventors: Michael Michaelides, Lee Arnold, Michael Curtin, Yujia Dai, Steven Davidsen, Robin Frey, Yan Guo, Zhiqin Ji, Neil Wishart
  • Substituted 7,8-dihydro-1H-pyrimido[4,5-b][1,4]diazepin-4-amines are novel kinase inhibitors
    Publication number: 20060270663
    Abstract: Compounds having the Formula (I) are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: May 12, 2006
    Publication date: November 30, 2006
    Inventors: Vijaya Gracias, Celerino Abad-Zapatero, Stevan Djuric, Zhiqin Ji, Michael Michaelides, Kent Stewart, Irini Zanze
  • Isoindolinone kinase inhibitors
    Patent number: 7129260
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: October 31, 2006
    Assignee: Abbott Laboratories
    Inventors: Michael L. Curtin, Steven K. Davidsen, Robin R. Frey, Howard R. Heyman, James H. Holms, Michael Michaelides, Douglas H. Steinman
  • Novel kinase inhibitors
    Publication number: 20060178378
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: October 28, 2005
    Publication date: August 10, 2006
    Inventors: Yujia Dai, Kresna Hartandi, Michael Michaelides
  • Aminobenzoxazoles as therapeutic agents
    Publication number: 20060025383
    Abstract: A compound of Formula (I), wherein the substituents are as defined herein, which are useful as kinase inhibitors.
    Type: Application
    Filed: February 3, 2005
    Publication date: February 2, 2006
    Inventors: Neil Wishart, Michael Friedman, Lee Arnold, Bryant Yang, Shannon Fix-Stenzel, Anna Ericsson, Michael Michaelides, Xiao-Dong Qian, James Holms, Douglas Steinman, Zhengping Tian, Steven Wittenberger
  • Tricyclic pyrazole kinase inhibitors
    Publication number: 20060014816
    Abstract: Compounds of the present invention are useful for inhibiting protein tyrosine kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: March 24, 2005
    Publication date: January 19, 2006
    Inventors: Lee Arnold, Jurgen Dinges, Richard Dixon, Stevan Djuric, Anna Ericsson, Kimba Fischer, Alan Gasiecki, Vijaya Gracias, James Holms, Makoto Takeshita, Michael Michaelides, Melanie Muckey, Paul Rafferty, Douglas Steinman, Carol Wada, Zhiren Xia, Irini Akritopoulou-Zanze, Henry Zhang
  • Thienopyridine and furopyridine kinase inhibitors
    Publication number: 20050043347
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: July 26, 2004
    Publication date: February 24, 2005
    Inventors: Patrick Betschmann, Andrew Burchat, David Calderwood, Michael Curtin, Steven Davidsen, Heather Davis, Robin Frey, Howard Heyman, Gavin Hirst, Peter Hrnciar, Michael Michaelides, Melanie Muckey, Paul Rafferty, Carol Wada
  • Thienopyridine and furopyridine kinase inhibitors
    Publication number: 20050026944
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: May 3, 2004
    Publication date: February 3, 2005
    Inventors: Patrick Betschmann, Andrew Burchat, David Calderwood, Michael Curtin, Steven Davidsen, Heather Davis, Robin Frey, Howard Heyman, Gavin Hirst, Peter Hrnciar, Michael Michaelides, Melanie Muckey, Paul Rafferty, Carol Wada
  • Isoindolinone kinase inhibitors
    Publication number: 20050026976
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: June 2, 2004
    Publication date: February 3, 2005
    Inventors: Michael Curtin, Steven Davidsen, Robin Frey, Howard Heyman, James Holms, Michael Michaelides, Douglas Steinman
  • Thienopyridine kinase inhibitors
    Publication number: 20050020619
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: July 24, 2003
    Publication date: January 27, 2005
    Inventors: Patrick Betschmann, Andrew Burchat, David Calderwood, Michael Curtin, Steven Davidsen, Heather Davis, Robin Frey, Howard Heyman, Gavin Hirst, Peter Hrnciar, Michael Michaelides, Paul Rafferty
  • Indazole, benzisoxazole, and benzisothiazole kinase inhibitors
    Publication number: 20050020603
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: May 10, 2004
    Publication date: January 27, 2005
    Inventors: Yujia Dai, Steven Davidsen, Anna Ericsson, Kresna Hartandi, Zhiqin Ji, Michael Michaelides
  • 3-substituted indole antiproliferative angiogenesis inhibitors
    Publication number: 20020091148
    Abstract: 3-Substituted indole carbohydrazides having the formula 1
    Type: Application
    Filed: September 14, 2001
    Publication date: July 11, 2002
    Inventors: Nwe Y. BaMaung, Richard A. Craig, Megumi Kawai, Jieyi Wang, Yujia Dai, Yan Guo, George Sheppard, Mary K. Verzal, Anil Vasudevan, Michael Michaelides
  • Trans-2,6-,3,6-and 4,6-diaza-5,6,6a,7,8,12b-hexahydrobenzo[c]phenanthrene compounds as dopamine agonists
    Patent number: 5668141
    Abstract: A tetracyclic compound of the formula: ##STR1## wherein A and the atoms to which it is attached comprise a pyridine ring selected from: ##STR2## wherein R.sup.1, R.sup.2, and R.sup.3 are specifically defined, which compounds are useful in the treatment of dopamine-related neurological, psychological and cardiovascular disorders as well as in the treatment of substance abuse and other addictive behavior disorders, cognitive impairment and attention deficit disorder, and methods for the preparation thereof.
    Type: Grant
    Filed: April 2, 1996
    Date of Patent: September 16, 1997
    Assignee: Abbott Laboratories
    Inventors: Kazumi Shiosaki, Yu Gui Gu, Michael Michaelides