Abstract: The present disclosure provides an electrophysiology system to facilitate visualizing a proximity of at least one catheter electrode to a 3D geometry of a biological tissue. The system includes a computing device including at least one processor in communication with a memory, wherein the processor is configured to determine the proximity between the at least one catheter electrode and the biological tissue using at least one measurement. The system further includes a display device configured to display the 3D geometry of the biological tissue and a visual effect illustrating the proximity between the at least one catheter electrode and the biological tissue.

Abstract: The disclosure provides driver components, systems and drive methods that facilitate improved dose setting, correcting, and/or dispensing in a multiple use pen-type injection device. In particular, various novel braking systems are disclosed that can be implemented within the pen-type injection devices to help achieve the improved dose setting, correcting, and/or dispensing.

Abstract: An injection method using an injection device having a housing, a dose set knob and a driver, where during dose setting and said dose correcting, the driver is prevented from rotating with the dose set knob while moving axially with said dose set knob, and during dose injecting the driver is engaged with the dose set knob thereby forcing the driver to rotate with the dose set knob. A clicker operatively engaged between the dose set knob and said driver provides audible or tactile indicia during dose setting or dose correcting. A dose stop member prevents further rotational movement of the dose set knob in a dose setting direction when the dose set knob is rotated to a last dose setting position.

Abstract: The present disclosure provides an electrophysiology system to facilitate visualizing a proximity of at least one catheter electrode to a 3D geometry of a biological tissue. The system includes a computing device including at least one processor in communication with a memory, wherein the processor is configured to determine the proximity between the at least one catheter electrode and the biological tissue using at least one measurement. The system further includes a display device configured to display the 3D geometry of the biological tissue and a visual effect illustrating the proximity between the at least one catheter electrode and the biological tissue.

Abstract: The disclosure provides driver components, systems and drive methods that facilitate improved dose setting, correcting, and/or dispensing in a multiple use pen-type injection device. In particular, various novel braking systems are disclosed that can be implemented within the pen-type injection devices to help achieve the improved dose setting, correcting, and/or dispensing.

Abstract: A medication injection pen, including a housing, a dose set knob (DSK) comprising an internal key, and a dose stop member engaging the dose set knob. Rotation of the dose set knob to set a medication dose causes rotation of the dose stop member with respect to the dose set knob, and when the dose set knob is rotated to a last dose setting position, the dose stop member rotationally abuts the internal key thereby preventing further rotational movement of the dose set knob in a dose setting direction.

Abstract: Molded latex foam blocks having dual densities and methods for the same are disclosed herein. The method may include preparing a latex composition including one or more rubber materials, disposing the latex composition into a mold, foaming the latex composition inside the mold, and curing the latex composition to produce a solid block of foam having dual densities. The solid block of foam may be a monolithic structure have a first side having a first density and a second side having a second density, where the first density is relatively greater than the second density.

Abstract: A medication injection method where a medication injection pen comprises a dose set knob rotatable with respect to a housing to set a desired injection dose. The dose set knob comprises at least one internal thread. A leadscrew includes a thread element for advancing in a first direction via a corresponding thread engagement. A driver is rotationally fixed to the leadscrew and is rotatable in a first direction to rotate and advance the leadscrew in the first direction. The setback member is rotationally fixed to the driver. The dose stop member is rotationally coupled to the setback member and is axially movable relative to the dose set knob when the dose set knob is rotated relative to the setback member. Axial movement of the dose stop member limits the user from setting a dose that is greater than an injectable volume of medication remaining in a cartridge.

Abstract: A substance dispensing apparatus comprises a housing for handheld use and a mouthpiece coupled to the housing. The housing comprises a biometric sensor and a cavity sized to receive a reservoir. The mouthpiece comprises a recess and a capacitive sensor array. The apparatus further comprises a pump coupled to the mouthpiece and couplable to the reservoir and comprises a processor in communication with the biometric sensor, capacitive sensor array, and pump. The processor is configured to cause the pump to automatically dispense a substance from the reservoir to a mouth of an intended user via the mouthpiece in response to determining that: a unique biometric attribute of the intended user is detected by the biometric sensor based on biometric data from the biometric sensor; and a unique dentition of the intended user is positioned within the recess of the mouthpiece based on dentition data from the capacitive sensor array.

Abstract: A photovoltaic (PV) module for solar power generation. The PV module comprises at least one PV element retained in a support tray. The support tray is formed of a rigid material and may not require the use of glass to provide structure stability to the PV module. The PV module may provide improved reliability and performance and may be produced by a more economical and less environmentally damaging manufacturing process. A method of forming such a PV module, a support tray for use in a PV module and a junction box for use with the PV module are also disclosed.

Abstract: A medication injection pen comprises a dose set knob rotatable with respect to a housing to set a desired injection dose. The dose set knob comprises at least one internal thread. A leadscrew includes a thread element for advancing in a first direction via a corresponding thread engagement. A driver is rotationally fixed to the leadscrew and is rotatable in a first direction to rotate and advance the leadscrew in the first direction. The setback member is rotationally fixed to the driver. The dose stop member is rotationally coupled to the setback member and is axially movable relative to the dose set knob when the dose set knob is rotated relative to the setback member. Axial movement of the dose stop member limits the user from setting a dose that is greater than an injectable volume of medication remaining in a cartridge.

Abstract: A medication injection pen comprises a dose set knob rotatable with respect to a housing to set a desired injection dose. The dose set knob comprises at least one internal thread. A leadscrew includes a thread element for advancing in a first direction via a corresponding thread engagement. A driver is rotationally fixed to the leadscrew and is rotatable in a first direction to rotate and advance the leadscrew in the first direction. The setback member is rotationally fixed to the driver. The dose stop member is rotationally coupled to the setback member and is axially movable relative to the dose set knob when the dose set knob is rotated relative to the setback member. Axial movement of the dose stop member limits the user from setting a dose that is greater than an injectable volume of medication remaining in a cartridge.

Abstract: An injection pen, comprising a housing, a lead screw axially moveable in the housing, a dose set member for dose setting and dose correcting, threadably connected to the housing and having a first mating feature, a setback member having a second mating feature for engaging the first mating feature, a clicker that generates an audible or tactile indication during operation, the clicker being operatively connected to the dose set member, and a push button operatively connected to the setback member to cause the second mating feature to engage the first mating feature during an injection, the push button receiving the clicker, wherein the first mating feature is disengaged from the second mating feature during dose setting and dose correcting and engaged with the second mating feature during an injection.

Abstract: An injection method is provided for using an injection pen, the injection pen comprising a housing, a lead screw axially moveable in the housing, a dose set member for dose setting and dose correcting, threadably connected to the housing and having a first mating feature, a setback member having a second mating feature for engaging the first mating feature, a clicker that generates an audible or tactile indication during operation, the clicker being operatively connected to the dose set member, and a push button operatively connected to the setback member to cause the second mating feature to engage the first mating feature during an injection, the push button receiving the clicker, wherein the first mating feature is disengaged from the second mating feature during the dose setting and the dose correcting and engaged with the second mating feature during the injection.

Abstract: A system for locating a leak site in an underground water pipeline comprises a leak detection element, means for introducing the leak detection element into the pipeline through an outlet of a hydrant, and means for detecting the location of the leak detection element from above the ground. The means for introducing the leak detection element into the pipeline includes capping means adapted for attachment to, and sealing of, the outlet of the hydrant. The capping means has at least one opening therethrough to allow passage of an elongate rod or hose through the capping means and into the outlet of the hydrant. The capping means is provided with a substantially waterproof membrane to provide a seal between the capping means and the outlet of the hydrant, and the at least one opening is provided with a substantially waterproof membrane to provide a seal between the rod or hose and the at least one opening. A method for locating a leak site in an underground water pipeline is also provided.

Abstract: A medication injection method where a dose set knob of a medication injection pen is rotated with respect to the housing of the medication injection pen during dose setting and dose correcting, a driver is selectively engages with the dose set knob, the driver being rotatably fixed with respect to the housing during dose setting and dose correcting, the driver is moved axially with the dose set knob during the dose setting and the dose correcting, and the driver is rotated with the dose set knob during an injection.

Abstract: A proportional valve is provided that comprises an input port (3) and an output port (5), with a diaphragm (19) therebetween. A diaphragm plate (21) with a pilot orifice (31) formed therethrough is mounted to the diaphragm (19). The valve has a solenoid (7) comprising an armature (15) and a field winding (17), with the armature being movable in an opening direction in response to a magnetic field generated by the field winding. A spring assembly (13) is arranged to provide a biassing force to the armature (15) in its closing direction. In its closed position, the diaphragm plate (21) sits in a main orifice (20) between the input and output ports to block flow of fluid therebetween, with the armature (15) blocking the pilot orifice (31). Opening movement of the armature (15) opens the pilot orifice (31) to allow fluid to flow therethrough, in turn allowing the diaphragm plate (21) to move out of the main orifice (20) to create a gap allowing flow of fluid from the input port (3) to the output port (5).

Abstract: A reduced profile syringe assembly is provided that includes an overall profile that is substantially similar to a profile of a syringe barrel. The syringe assembly includes a plunger rod that is significantly disposed within the syringe barrel when filled for use, with the plunger rod adapted to be retracted from the syringe barrel during dispensing of contents of the syringe barrel.

Abstract: A medication injection method where a dose set knob of a medication injection pen is rotated with respect to the housing of the medication injection pen during dose setting and dose correcting, a driver is selectively engages with the dose set knob, the driver being rotatably fixed with respect to the housing during dose setting and dose correcting, the driver is moved axially with the dose set knob during the dose setting and the dose correcting, and the driver is rotated with the dose set knob during an injection.

Abstract: A medication injection pen, including a housing, a dose set knob (DSK) comprising an internal key, and a dose stop member engaging the dose set knob. Rotation of the dose set knob to set a medication dose causes rotation of the dose stop member with respect to the dose set knob, and when the dose set knob is rotated to a last dose setting position, the dose stop member rotationally abuts the internal key thereby preventing further rotational movement of the dose set knob in a dose setting direction.