Abstract: Described herein are compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies. In particular embodiments, the disclosure provides fully human anti-ST2 antibodies and deriviatives and variants thereof. Further provided are nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives. Also, provided are methods of making and using such antibodies including methods of treating and preventing autoimmune and inflammatory disorders.

Abstract: A connector for coiled tubing may include a main body configured for welding to a free end of the coiled tubing and having an internal stem extending distally therefrom. The stem may include a sleeve portion and the connector may include an alignment sleeve arranged on the sleeve portion of the stem and being free to rotate relative to the stem. The alignment sleeve may have a longitudinally extending groove on an outside surface thereof for receiving a longitudinal weld bead on an inside surface of the coiled tubing.

Abstract: A testing device includes a first member to be positioned on one surface of a part to be tested. A second member to be positioned on an opposed surface of the part to be tested. One of the first and second members have an ultrasonic transmitter and the other has an ultrasonic receiver. At least one of the first and second members have at least one magnetic element and the other of the first and second member have at least one magnetic or at least one ferromagnetic metallic element such that when one of the first and second members moves along the surface of the tested part the other of the first and second members will move along an opposed surface with the one of the members.

Abstract: A method of testing a part includes placing a first member on a part to be tested. A second member is placed on an opposed surface of the part. One of the members has an ultrasonic transmitter and the other has an ultrasonic receiver. At least one of the members has at least one magnetic element and the other has at least one of a magnetic element or a ferromagnetic metallic element which is attracted to magnets. One of the members moves along the surface of the part such that magnetic attraction causes the other to move along the opposed surface of the part with the one of the members. A controller causes an ultrasonic signal to be sent from the transmitter through the part to be tested which is received by the receiver and then analyzed by an ultrasonic testing machine.

Abstract: A composite drive shaft includes a web-based body defining a longitudinal axis. The web-based body has a first composite layup end section, a second composite layup end section that is opposite to the first composite layup end section, a first spiral composite element extending between the first composite end section and the second composite layup end section, and a second spiral composite element extending between the first composite end section and the second composite layup end section. The first spiral composite element and the second composite spiral element are embedded into the first composite layup end section, and the second composite layup end section. The first composite spiral element and the second composite spiral element are arranged in a bi-directional orientation relative to the longitudinal axis. The first spiral composite element and the second spiral composite element are arranged at pre-determined angles and possess a uni-directional fiber-reinforced polymer-matrix composite structure.

Abstract: The invention relates to direct-fed microbials for use in E. coli, Salmonella, and/or Campylobacter inhibition in animals. More particularly, the invention relates to isolated Bacillus strains A12, 54, 681, 101, 235, and 721, and strains having all of the identifying characteristics of these strains, for a use comprising the above-mentioned use. The invention also relates to the use of isolated Bacillus strains 681,721, A12, 54, 86, 300, 101, 102, 235, and 177, and strains having all of the identifying characteristics of these strains, to prevent or reduce prolapse in an animal.

Abstract: A flexible diaphragm coupler includes a flange having a central support and a flange element extending radially outwardly from the central support. The flange element includes a rim portion having an axially facing surface. The axially facing surface includes a plurality of interlock elements. A diaphragm member is disposed between the first flange and the second flange. The diaphragm member includes a diaphragm element. The diaphragm element includes a central support element and a disc member extending radially outwardly from the central support element. The disc member includes a rim element having an axially facing surface portion including a plurality of interlock members that connect with the plurality of interlock elements.

Abstract: Apparatus and methods for extracellular vesicle enrichment are described in which apparatus may be used to create plasma preparations that are enriched in EV-containing fluid sample. Generally, one variation of a method may generally comprise contacting the fluid sample with a plurality of absorbent chromatographic beads to concentrate EVs from the fluid sample, and separating the beads from the fluid sample.

Abstract: The invention relates to treatment of waste with one or more microorganisms for the purposes of, including but not limited to, degrading waste, bioremediation of waste, enhancing waste stabilization, reducing contaminants in waste, reducing odor in waste, reducing organics in waste, and combinations thereof. More particularly, the invention relates to isolated Bacillus strains, and strains having all of the identifying characteristics of these strains, and combinations thereof, for uses comprising the above-mentioned uses.

Abstract: The invention relates to direct-fed microbials for use in E. coli inhibition in animals in combination with enrofloxacin. More particularly, the invention relates to isolated Bacillus strains 9, 57, 71, and 126, and strains having all of the identifying characteristics of these strains, for a use comprising the above-mentioned use.

Abstract: The invention relates to direct-fed microbials for use in E. coli inhibition in animals in combination with antibiotics selected from the group consisting of ceftiofur, oxytetracycline, tulathromycin, and lincomycin. More particularly, the invention relates to isolated Bacillus strains 2, 3, 4, 5, 9, 57, 71, and 126, and strains having all of the identifying characteristics of these strains, for a use comprising the above-mentioned use.

Abstract: The invention relates to treatment of a plant with one or more microorganisms for inhibiting a plant pathogen. More particularly, the invention relates to isolated Bacillus strains, and strains having all of the identifying characteristics of these strains, and combinations thereof, for a use comprising the above-mentioned use.

Abstract: The invention relates to treatment of waste with one or more microorganisms for the purposes of, including but not limited to, degrading waste, bioremediation of waste, enhancing waste stabilization, reducing contaminants in waste, reducing odor in waste, reducing organics in waste, and combinations thereof. More particularly, the invention relates to isolated Bacillus strains, and strains having all of the identifying characteristics of these strains, and combinations thereof, for uses comprising the above-mentioned uses.

Abstract: The invention relates to treatment of a plant with one or more microorganisms for inhibiting a plant pathogen. More particularly, the invention relates to isolated Bacillus strains, and strains having all of the identifying characteristics of these strains, and combinations thereof, for a use comprising the above-mentioned use.

Abstract: The invention relates to direct-fed microbials for use in E. coli and/or Clostridium inhibition in animals in combination with antibiotics. More particularly, the invention relates to isolated Bacillus strains 2, 3, 4, 5, 6, 7, 9, 57, 71, and 126, and strains having all of the identifying characteristics of these strains, for a use comprising the above-mentioned use.

Abstract: The invention relates to compositions comprising microbial strains and methods for use of the compositions in removing pollutants in waste, water, or soil, such as remediating dye and lignin, reducing contaminants, degrading paper (such as flushable or disposable or non-flushable wipes), reducing odor, reducing chemical oxygen demand (COD), and combinations thereof, in the water, the soil, or the waste or for use in administration to animals in the feed or drinking water of the animals. More particularly, the invention relates to compositions of isolated Bacillus strains selected from the group consisting of isolated Bacillus strains Bacillus licheniformis MDG-1000 (NRRL No. B-67888), Bacillus licheniformis MDG-1001 (NRRL No. B-67889), Bacillus subtilis/amyloliquefaciens MDG-8001 (NRRL No. B-67890), Bacillus pumilus MDG-1047 (NRRL No. B-67891), Bacillus amyloliquefaciens MDG1607 (NRRL No. B-67666), Bacillus subtilis MDGV18 (NRRL No. B-67665), Bacillus pumilus MDGV17 (NRRL No.

Abstract: The invention relates to direct-fed microbials for use in E. coli inhibition in animals. More particularly, the invention relates to isolated Bacillus strains 101, 235, 77, 177, and 102 and strains having all of the identifying characteristics of these strains, for a use comprising the above-mentioned use. The invention can also be used for treatment of plants and in food processing.

Abstract: The invention relates to compositions comprising microbial strains for use in inhibiting viruses, and methods therefor. More particularly, the invention relates to compositions of isolated Bacillus strains selected from the group consisting of isolated Bacillus strains 300, 86, 101, 235, 102, 177, A12, 54, 681, 721, strains having all of the identifying characteristics of these strains, and combinations thereof, and methods for use of these strains for virus inhibition.

Abstract: The present invention is directed to direct-fed microbials for use in improving the performance of an animal, improving the health of an animal, improving the environment of an animal, and combinations thereof. More particularly, the invention relates to isolated Bacillus strains 86 and 300, and strains having all of the identifying characteristics of these strains, for uses comprising the above-mentioned uses.

Abstract: The present disclosure describes engineering of cells to co-express TNF-Related Apoptosis-Inducing Ligand (TRAIL) and Decoy Receptor 1 (DcR1). The expression of DcR1 results in competition for TRAIL binding to Death Receptors 4 and 5, thereby protecting the engineered cells from TRAIL-induced apoptosis. Such cells will exhibit longer survival such as when used in cell-based therapies for cancer.