Abstract: A folding knife is provided with a deflectable pivot that provides a varying bias force as the blade is rotated between the closed and open positions. Specifically, the pivot secures the blade to bias members of a handle, and the bias members deform relative to other parts of the handle to allow the pivot to move and to provide the varying bias force. A cam surface on the tang of the blade operatively engages a pin of the handle to control the deflection of the pivot and the bias members. The cam surface and the resulting bias force are arranged to locate and keep the blade in the open or closed positions like a detent mechanism to reduce the likelihood of an unintentional opening or closing of the blade and to improve the safety of the folding knife.

Abstract: Phenotyping of cells involves loading a biological sample into a microfluidic device (1, 100) comprising cell compartments (20, 120) to capture biological material, including target cells, in the sample in the cell compartments (20, 120). A subset (20A) of the cell compartments (20, 120) is identified as comprising target cells exhibiting target phenotype characteristic(s) as determined based on monitoring biological material in the cell compartments (20, 120) prior to addition of a test agent. The biological material is exposed to a test agent and a phenotypic response of the target cells to the test agent is determined based on monitoring target cells in the identified subset (20A) of the cell compartments (20, 120). The phenotyping of the target cells is thereby not overshadowed by the response of other cells and non-cell material present in the biological sample.

Abstract: An apparatus and method of analysis including at least one microscope means operable to characterize the surface of a sample in use, at least a first conduit to convey one or more solvents to the sample and a further conduit to convey at least part of the solution from the sample. At least one pump means delivers solvent to the sample and/or removes solution from the same.

Abstract: A method for delivering a benefit agent to the surface of the eye, the method comprising applying an ocular benefit composition to a lid margin of the eye wherein the ocular benefit composition comprises at least 5 wt % of one or more lipid and/or lipid derived compounds.

Abstract: A coupled cavity traveling wave tube has periodic permanent magnet (PPM) RF cavity structures, each of which has a plurality of permanent magnets placed substantially equidistant from a central axis, and which are outside the extent of a plurality of electron beam tunnels arranged substantially equidistant from the central axis and within the extents of the plurality of permanent magnets. Each coupled cavity RF structure is formed by adjacent ferrous polepieces and a cylindrical wall which is beyond the extent of one or more coupling apertures which couple RF energy from one coupled cavity structure to an adjacent RF cavity.

Abstract: Phenotyping of cells involves loading a biological sample into a microfluidic device (1, 100) comprising cell compartments (20, 120) to capture biological material, including target cells, in the sample in the cell compartments (20, 120). A subset (20A) of the cell compartments (20, 120) is identified as comprising target cells exhibiting target phenotype characteristic(s) as determined based on monitoring biological material in the cell compartments (20, 120) prior to addition of a test agent. The biological material is exposed to a test agent and a phenotypic response of the target cells to the test agent is determined based on monitoring target cells in the identified subset (20A) of the cell compartments (20, 120). The phenotyping of the target cells is thereby not overshadowed by the response of other cells and non-cell material present in the biological sample.

Abstract: An apparatus and method of analysis including at least one microscope means operable to characterize the surface of a sample in use, at least a first conduit to convey one or more solvents to the sample and a further conduit to convey at least part of the solution from the sample. At least one pump means delivers solvent to the sample and/or removes solution from the same.

Abstract: A compact wheel loader having a hydrostatic transmission and two modes of operation. In a normal mode, a demand lever is used to set the engine speed, and displacement of the swash plate of the hydraulic pump of the transmission is set by a hydraulic pilot pressure (Ps) that increases with engine speed, so that the transmission ratio automatically decreases as the engine speed increased. In a creeper mode, the engine is set to operate at a high speed to meet the demand of powered implements of the loader, and the wheel speed is controlled by the demand lever setting the transmission ratio by varying the hydraulic pilot pressure (Ps).

Abstract: An apparatus and method of analysis including at least one microscope means operable to characterize the surface of a sample in use, at least a first conduit to convey one or more solvents to the sample and a further conduit to convey at least part of the solution from the sample. At least one pump means delivers solvent to the sample and/or removes solution from the same.

Abstract: A method for delivering a benefit agent to the surface of the eye, the method comprising applying an ocular benefit composition to a lid margin of the eye wherein the ocular benefit composition comprises at least 5 wt % of one or more lipid and/or lipid derived compounds.

Abstract: A compact wheel loader having a hydrostatic transmission and two modes of operation. In a normal mode, a demand lever is used to set the engine speed, and displacement of the swash plate of the hydraulic pump of the transmission is set by a hydraulic pilot pressure (Ps) that increases with engine speed, so that the transmission ratio automatically decreases as the engine speed increased. In a creeper mode, the engine is set to operate at a high speed to meet the demand of powered implements of the loader, and the wheel speed is controlled by the demand lever setting the transmission ratio by varying the hydraulic pilot pressure (Ps).

Abstract: An apparatus and method of analysis including at least one microscope means operable to characterize the surface of a sample in use, at least a first conduit to convey one or more solvents to the sample and a further conduit to convey at least part of the solution from the sample. At least one pump means delivers solvent to the sample and/or removes solution from the same.

Abstract: A system for controlling a defrost cycle of an evaporator having a sensor module and a control module. The sensor module includes a light source configured to emit light toward the evaporator when activated and to deactivate in response to a lockout signal. The sensor module also includes a light sensor configured to determine an amount of the emitted light reflected by the evaporator and to generate a detected light signal that corresponds to the amount of the emitted light reflected by the evaporator. The control module is configured to receive the detected light signal from the light sensor and to compare the detected light signal to a preset threshold. The control module is also configured to generate a termination signal when the detected light signal is less than the preset threshold and to generate the lockout signal when the detected light signal is greater than the preset threshold.

Abstract: A refrigeration system includes a normal refrigerant path arranged between a condenser and an evaporator, and an assist refrigerant path arranged between the condenser and the evaporator, wherein the assist refrigerant path is activated during low ambient conditions. The assist refrigerant path may include a solenoid valve and an expansion valve arranged between the condenser and the evaporator. The assist refrigerant path may be adapted to regulate the evaporator temperature.

Abstract: A periodic permanent magnet (PPM) klystron has beam transport structures and RF cavity structures, each of which has permanent magnets placed substantially equidistant from a beam tunnel formed about the central axis, and which are also outside the extent of a cooling chamber. The RF cavity sections also have permanent magnets which are placed substantially equidistant from the beam tunnel, but which include an RF cavity coupling to the beam tunnel for enhancement of RF carried by an electron beam in the beam tunnel.

Abstract: In one or more embodiments, the present disclosure provides for a process for preparing a dispersion of starch particles in an aqueous liquid. In one or more embodiments, the process includes introducing a feed starch and the aqueous liquid into a rotor stator mixer, maintaining the feed starch and the aqueous liquid in the rotor stator mixer at a temperature ranging from a gelation temperature to less than a solubilization temperature, and shearing the feed starch into starch particles with the rotor stator mixer to form the dispersion of starch particles in the aqueous liquid. In one or more embodiments, the starch particles produced by this process have an average particle size diameter of no larger than 2 micrometers and the dispersion has 20 to 65 weight percent of the starch particles based on a total weight of the dispersion.

Abstract: An AFM based technique has been demonstrated for performing highly localized IR spectroscopy on a sample surface. Such a technique implemented in a commercially viable analytical instrument would be extremely useful. Various aspects of the experimental set-up have to be changed to create a commercial version. The invention addresses many of these issues thereby producing a version of the analytical technique that can be made generally available to the scientific community.

Abstract: A multi-beam electron gun provides a plurality N of cathode assemblies comprising a cathode, anode, and focus electrode, each cathode assembly having a local cathode axis and also a central cathode point defined by the intersection of the local cathode axis with the emitting surface of the cathode. Each cathode is arranged with its central point positioned in a plane orthogonal to a device central axis, with each cathode central point an equal distance from the device axis and with an included angle of 360/N between each cathode central point.

Abstract: The present invention relates to a communications system (1) for making multimedia calls. The system comprises two multimedia terminals (10,12) and communication means for making a multimedia call over a shared communications network (20), including a firewall (26) through which the multimedia call must pass, and which restricts certain types of communication. Each terminal (10,12) has a number of logical communication ports for the multimedia call, including at least one dynamically assigned port. In the course of setting up the multimedia call, at least one of the terminals (10,12) is adapted to send a request to the other of the terminals to open up one or more of the dynamic ports in the other terminal. The system includes a proxy server (40) between the terminals (10,12) that acts for each terminal as a proxy for the other terminal during the course of the call. The proxy server (40) has logical communication ports for communication with the terminals including one or more pre-assigned ports.