Abstract: An AFM based technique has been demonstrated for performing highly localized IR spectroscopy on a sample surface. Significant issues as to size, cost of implementation, and repeatability/robustness of results exist in commercializing the technique. The invention addresses many of these issues thereby producing a version of the analytical technique that can be made generally available to the scientific community.

Abstract: An AFM based technique has been demonstrated for performing highly localized IR spectroscopy on a sample surface. Significant issues as to size, cost of implementation, and repeatability/robustness of results exist in commercializing the technique. The invention addresses many of these issues thereby producing a version of the analytical technique that can be made generally available to the scientific community.

Abstract: A method of performing a multimedia communication session over a communication link using Transmission Control Protocol (TCP) and over a communication link using User Datagram Protocol (UDP), including the acts of: receiving a request, over the TCP link, to register from a client terminal located within a private network; a probe data packet to the client terminal, over the TCP link, requesting to send a data packet over the UDP link; and receiving a data packet from the client terminal that contains information relating to an address of the client terminal and a dynamic port over which the multimedia communication session is to be established.

Abstract: A system and method for automatic analysis of temperature transition data over an area of a sample surface. The system relies on the use of a microfabricated probe, which can be rapidly heated and cooled and has a sharp tip to provide high spatial resolution. The system also has fast x-y-z positioners, data collection, and algorithms that allow automatic analysis of and visualization of temperature transition data.

Abstract: An AFM based technique has been demonstrated for performing highly localized IR spectroscopy on a sample surface. Such a technique implemented in a commercially viable analytical instrument would be extremely useful. Various aspects of the experimental set-up have to be changed to create a commercial version. The invention addresses many of these issues thereby producing a version of the analytical technique that cab be made generally available to the scientific community.

Abstract: An AFM based technique has been demonstrated for performing highly localized IR spectroscopy on a sample surface. Such a technique implemented in a commercially viable analytical instrument would be extremely useful. Various aspects of the experimental set-up have to be changed to create a commercial version. The invention addresses many of these issues thereby producing a version of the analytical technique that cab be made generally available to the scientific community.

Abstract: Manufacturing of miniaturised three-dimensional electric components are presented, as well as components manufactured by the methods. The manufacturing methods comprise micro-replication of at least one master structure, e.g. via a mould structure, in at least one polymer layer onto which layer at least one conductive path is provided.

Abstract: A process for assembling molecules on a surface, the process comprising: providing a probe having a variable-temperature tip; providing a first material, which is optionally on a first surface of a substrate; bringing the tip of the probe into contact with the first material, whereby molecules of the first material are transferred to the tip; and moving the tip of the probe to a position above a surface of a second material (the second surface); then heating the tip of the probe to a temperature T2, at which the first material will transfer from the tip to the surface of the second material. Analytical process using this method are also disclosed.

Abstract: A system and method for automatic analysis of temperature transition data over an area of a sample surface. The system relies on the use of a microfabricated probe, which can be rapidly heated and cooled and has a sharp tip to provide high spatial resolution. The system also has fast x-y-z positioners, data collection, and algorithms that allow automatic analysis of and visualization of temperature transition data.

Abstract: A modulated differential scanning calorimeter that accounts for heat flow due to evaporative solvent loss. The calorimeter modulates the temperature applied to a sample and a reference to determine the amount of heat flow that is due to evaporation. By calculating the amount of heat flow due to evaporation, the user can determine how much of the heat flow of any given well is due to the process of interest as opposed to evaporation.

Abstract: A method of performing a multimedia communication session over a communication link using Transmission Control Protocol (TCP) and over a communication link using User Datagram Protocol (UDP), including the acts of: receiving a request, over the TCP link, to register from a client terminal located within a private network; a probe data packet to the client terminal, over the TCP link, requesting to send a data packet over the UDP link; and receiving a data packet from the client terminal that contains information relating to an address of the client terminal and a dynamic port over which the multimedia communication session is to be established.

Abstract: The present invention relates to a communications system (1) for handling communications sessions, for example multimedia calls or voice calls. The communications system (1) comprises a local terminal (10), an external server (40), a proxy interface agent (PIA) (11) between the terminal (10) and a shared network (20). The communication means includes a NAT function (32) through which the communications session must pass. The communications session is carried over the network (20) over one or more logical channels between the terminal (10) and the external server (40), during which the first NAT function (32) applies network address mappings on the terminal's transport addresses (14). The PIA (11) acts on behalf of the terminal (10) in communications with the external server (40), and establishes a logical channel on an outbound connection to the server that serves as a control channel between the PIA (11) and the server (40).

Abstract: A method for using a neural network to deconvolute the effects due to surface topography from the effects due to the other physical property being measured in a scanning probe microscopy (SPM) or atomic force microscopy (AFM) image. In the case of a thermal SPM, the SPM probe is scanned across the surface of a sample having known uniform thermal properties, measuring both the surface topography and thermal properties of the sample. The data thus collected forms a training data set. Several training data sets can be collected, preferably on samples having different surface topographies. A neural network is applied to the training data sets, such that the neural network learns how to deconvolute the effects dues to surface topography from the effects dues to the variations in thermal properties of a sample.

Abstract: Manufacturing of miniaturised three-dimensional electric components are presented, as well as components manufactured by the methods. The manufacturing methods comprise micro-replication of at least one master structure, e.g. via a mould structure, in at least one polymer layer onto which layer at least one conductive path is provided.

Abstract: A nozzle chip (3) for ejecting a liquid such as in an electrospray device is built from a substrate chip having grooves (5, 7) on a top surface. A lid (25) is attached to the top surface closing the grooves to form channels one of which has an open outlet end (9). At the outlet end a nozzle is formed at or attached and it has an outlet opening from which the liquid is to be ejected. Alignment recesses (13, 15) are made at edges of the substrate chip and they are accurately positioned in relation to the outlet opening, the alignment recesses allowing an accurate mounting of nozzle chip giving the outlet opening of the nozzle a reproducible position in the device where it is to be used. At the outlet end a recess (17) in the substrate chip can be provided and the nozzle can then be located in the recess to mechanically protect it.

Abstract: A method and a system for generating a high spatial resolution multi-dimensional image representing the chemical composition of a sample. Highly localized IR light is used to cause the heating and thermal expansion of the sample. Modulating this IR light will cause this effect to take place at various depths of the material. The method and system of the present invention are used to generate a chemical profile of the sample using a combination of: (i) measurements of the thermal expansion and temperature change caused by absorbing IR radiation together; and (ii) measurements of the thermal expansion properties and thermal properties (such as thermal diffusivity and conductivity) of sites on the surface of the sample and the material surrounding it.

Abstract: The invention provides novel lipid soluble forms of tricyclic antineoplastic compounds. These forms include salts, co-crystals, and solvates of the tricyclic antineoplastic compounds. The invention also provides novel pharmaceutical compositions comprising these novel lipid soluble forms and related methods of treatment. Compositions and methods of the invention are useful in the treatment of neoplasms, including MRP-1-related resistant neoplasms.

Abstract: Engine speed data (N) and engine fueling data (MFDES) are processed to develop rate-of change data values for both engine fueling (FUELING_DIFFERENCE_FILTERED) and engine speed (ENGINE SPEED_DIFFERENCE_FILTERED). The latter are processed according to a look-up table (30) to select a data value for an adder (ENGINE SPEED/FUELING_ROC_ADDER). The adder data value is added to the data value of a control parameter, such as engine fueling (MFDES), to compensate for engine transients.

Abstract: The invention relates to polymers derived from macrocyclic oligomers containing organo clay fillers. The invention also relates to processes for preparing such compositions. Furthermore, the invention relates to articles prepared from organoclay filled polymer compositions.

Abstract: Manufacturing of miniaturised three-dimensional electric components are presented, as well as components manufactured by the methods. The manufacturing methods comprise micro-replication of at least one master structure, e.g. via a mould structure, in at least one polymer layer onto which layer at least one conductive path is provided.